Conserved Protein Domain Family
PRK06241

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PRK06241: PRK06241 
phosphoenolpyruvate synthase; Validated
Statistics
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PSSM-Id: 235751
Aligned: 78 rows
Threshold Bit Score: 831.072
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
304309890  20 SLPLFLSQQDALFLPPESLGGKAMNLAWLSREGFPVPRWWVLTTEAFQQLLEANQLDGWIEGVLSDAQLLeDSALLEAAA 99  
42524538    1 ---MLVTPKSTLFFAKNEAGGKGFNLYLMSQAGLPVPEWVVFGKRYFHEFLQSADVKVRLEGILDRL-LR-QELTPALAE 75  
125717849   1 -------MKRIKQTGLDQVGGKAYHLLKMQAAGLPVPDFAVFAFDFFQNSTSSAD-----LERMEAAYRS-GELDLSQLS 67  
157151134   1 -------MKRIKQTGLDQVGGKAYHLLKMQAAGLPVPDFAVFAFDFFQTSASSA-----DLEQMEATYRS-GELDLFQLS 67  
37528329    7 NMKYLYTQDNAIELAEHSLGGKAANLLWLTQNGFPVPNYWVISSEVLNNLLINDTFASNIIEQLATVPHDiSQEKLDAIA 86  
253991484  14 NMKYLYTQDNAIKLAEHSLGGKAANLLWLTQNGFPVPNYWVISSEVLNSLLANDTFAINIVEQLAAVPHDiSQEKLDAIA 93  
295681466  36 SPHVILTAASPAETIERLAGNKGRSLHRLANLGVAVPHWAILGTDCFAEFRRDG----GLDQTIAALLSDfTPANAAAIA 111 
145596653   1 MSTVAI---ETDVTKWRAMGAKASNLAAMRNLGVHVPRWSAVSSDVFTAFLERVEGIDVLLTQ--------GTEEPERVA 69  
159038571   1 ---MSTVASETDVTKWRAMGAKASNLAAMRSLGVHVPRWSAVSSDVFTAFLEHVEGIDVLLTQ--------GTEEPERVA 69  
296393758   1 MSSALLRSGDVLAAGVDRVGGKAMGLARLESAGARVPHWAVLGVEAFQAHLCQAGLAEQAAELVCAGLRG---EASGAAA 77  
304309890 100 RAIRERVLSASIPESLIEIVTRHLA--GQeDCYFAVRSSVLGEDALGASFAGQMDSYLFQRGLPAILESILQVAASAFNA 177 
42524538   76 KEVLSLFESTPLPATVESSLEEALHslGS-DKVFSVRSSAADEDSLSHSFAGQLSSYLYVSGKADILKYIRQCWASAFSE 154 
125717849  68 QQLQTWAIKQFSQEDLSVAESWVRKefFQtDCRFAVRSSATIEDGKSSSFAGQFESQLNVK-PEGLKEAIQATLLSLYQE 146 
157151134  68 QQLQDWAREQFGQEDLTVAENWIRQefSQkDCRFAVRSSATIEDGKVSSFAGQFESQLNVK-TEGLKEAIQATLLSLYQE 146 
37528329   87 APLRQWLQSIPLPAKLEEELALLSEnhPD-EF-FAVRSSAIGEDAANASFAGQMDSYLFQRGKSALANSLRAVMASAFNT 164 
253991484  94 APLRQWLKSLPLPEELEEELALLSEnhP--DTFFAVRSSAIGEDAANASFAGQMDSYLFQRGKSALADSLRAVMASAFNT 171 
295681466 112 SQIREAVLTCDISATLRADIACARDtiG--DGPLAVRSSGVEEDSASFSFAGQFDTFLDVRGLDSTLEHVRRCWASAYSE 189 
145596653  70 AEVTRRMRATVLPDHLADPIQAAYQaaGG-GRV-AVRSSGLEEDGDRYSFAGQFDTFLNVSEADEVLDRVKDCWASAFSA 147 
159038571  70 AEVTRRMRATVIPDHLADPIHAAYQaaGG--GQVAVRSSGLEEDGDKYSFAGQFDTFLNVSEADEVLDRVKDCWASAFSA 147 
296393758  78 RALQQAICDYPLDPAVGEALRTFLDsaEP----LAVRSSATGEDGADHSFAGVYTSYLYRQGLDQVADAIRACWASAFSE 153 
304309890 178 RALQYRISKGIALAEIRAAVIVQEMVEGEISGVMFTAHPMSGSRRHALISATFGVGEGVVSGICNTDEYTVGlfDDSVV- 256 
42524538  155 RGLVYRLENKIDLKKISVSVVLQRMIDPDKSGVLFTCDPVAKKTDTFVVSSVYGVGEGLVSGALDADSFWLDakSGKMLr 234 
125717849 147 SALSYLFEQGLSLKQAQMICLVQIMQEGDLSGIYFTANPKGILNEHIIV-IGRGLGNKVVEDKIPTTMVTLH-------- 217 
157151134 147 SALSYLFEQGLSLKQAQMICLVQDMQEGDLSGIYFTANPKGILNEHIIV-IGRGLGNKVVEDKVPTTMVTLH-------- 217 
37528329  165 RALQYRLHKRLPMGNISSAVIIQNMVAGEVSGVMFTAHPVTGSRQHCLISSAWGTGEGVVSGECDTDEFSVHl-TSPEIe 243 
253991484 172 RALQYRLHKRLPMGNIRSAVIIQDMVAGEVSGVMFTAHPVTGSRQHYLISSAWGTGEGVVSGECDTDEFSVHltMPKIEh 251 
295681466 190 RSLRYRHQHGLDMAGAGMAVILQRLVQADTSGVVFTINPANGNRDELVLSAVYGLGEGLVSGAVDADTITVDrqTGQYKq 269 
145596653 148 RSLTYRLRNGLPLRATGMGVLIQQMVRSEVSGVLFTADPATGAGDRYVVSAVYGLGEGIVSGAVDADTATLEaaTGTVLa 227 
159038571 148 RSLTYRLRNGLPLRATGMGVLIQQMVRSEVSGVMFTADPATGAGDRYVVSAVYGLGEGIVSGAVDADTVTLEaaTGTVLe 227 
296393758 154 RALAYRRASGRNDDSVGVGVVVQHMATGDVSGVMFTRNPVTEAADEMLISACWGLGEGVVDGSCNTDEFLVSh-EGYEIs 232 
304309890 257 TTLGDKDLAlVFDHQRGrGTCEVSIEAARRKVACLDHRQLLALRDMGKKIAGLQKFPQDIEWTIRKGVVHILQTRPVTRL 336 
42524538  235 EELVEKKEM-MKKSASG-HCEMKPVSADKVNTASLNSEEMNGLYRLGQKIQEQYHRPQDIEWAVESGKIYILQTRPVTSL 312 
125717849 218 ------------------PKDQLFYTEQTEDSPDLSQEQLEELQALASQVSQLFGPYMDMEFTFANGWLYLLQARPITTL 279 
157151134 218 ------------------PKDQLFYTEQTENSPDLSQQQLEELQGLASQVSQLFGPYMDMEFTFANGQLYLLQARPITTL 279 
37528329  244 RHITQKETAtVFNTTNGsGTVTIPVAKEKQSEPTLLDNKIYALRDIGKEIAAARGCPQDIEWTIQNHQIFILQTRPITRL 323 
253991484 252 HITQKGTASiFDTANGS-GTVTVPVAEEKQWVPTLSDDEIYALRDIGKKIAAARGCPQDIEWTVQDHQIFILQTRPITRL 330 
295681466 270 VVIGEKRER------HD-GRHIREVPAALRDAAALSNDEIERVVAAARTLESKFGEPLDIEWCIAEHQLWILQARPVTT- 341 
145596653 228 TELGDKSER--YEPAAGgGVEAVEVPDADRAQLSLDRVDLGTLWEAGRAISDAFGAPQDIEWAVADGQLWILQSRPITTV 305 
159038571 228 TELGDKSER-YEPAAGG-GVEAIEVPDADRAQLSLDRIDLGTLWEAGRAISDAFGAPQDIEWAVADGQLWILQSRPITTV 305 
296393758 233 ATIADKDV--MVVRADGqGTKQVAVPAGRRDLRCLTPAQTEELARTGLAVASALGSPQDIEWTFRGDELVLLQTRPITTL 310 
304309890 337 ------PPL-SEsigevrvfdn--sniqesycgVTTPLTFSFASRAYETVYEQTMRLLGVSER-SVLAhrhmlENM---- 402 
42524538  313 dqdligYPNlwdnsni-----------iesyggLTSPLSFSFALRNYKAVYVQFCEVLGVPND-IIKDmdsylSYM---- 376 
125717849 280 ----------PEgqqiildns----nivesypgVSSPLTISFIQEAYASIFRSLAQRLVGKDApELATyeatfQNM---- 341 
157151134 280 ----------PEgqqiildns----nivesypgVSSPLTISFIQEAYASIFRSLAQRLVGKYApELAAyeatfQNM---- 341 
37528329  324 ------PRLdDKsehhiifdn---sniqesycgITTPLTFSFARAGYATVYEQTIRALGCSDK-QVNQhrsmlENM---- 389 
253991484 331 ------PRLdDKnehriifdn---sniqesycgITTPLTFSFARAGYATVYEQTIRALGCSDK-QVNQhrsmlENM---- 396 
295681466 342 -------PVaPAqsragdfqlwdnsnivenypgVTTQLTFTFAQHVYAQVFREFCRLLAIPHK-QRREmdgflGST---- 409 
145596653 306 ------PTA-SRpvgelriwdn--snivesfrgITSPLTFTFASTVYGAVYESYARSLHVPEK-QLAQmhewlPAL---- 371 
159038571 306 ------PTT-SRpvgelriwdn--snivesfrgITSPLTFTFASTVYGAVYESYARSLRVPEK-QLAQmhewlPAL---- 371 
296393758 311 ------RSA-PLgdwqtvwdn---sniqesfngVTLPLTFSWASAVYRAIFRETLRLLGVRAK-KIRD-----YEPmlrn 374 
304309890 403 -LGLVRGRVYYNINHwyqglllLPSFRSNKADMERMMGLTDPVDLVQDKNPGLSEKLRKLPQVLraLLRLLY----GFQR 477 
42524538  377 -LGSLNGRVYYNLFNwyklvgvLPGFKQNREFMETMMGVSEALSDEIANRIKPHPSWDTPVGRLrkAITGFNfi-kYHFT 454 
125717849 342 -LQPVNSRVYYQIQSwy----qLLQLLPFSKKIIPIW---QDMLGVRETEVPQMPVHMTAFKRLqiMLRIIRefwtGPKQ 413 
157151134 342 -LQPVNSRVYYQIQSwyqllqlLPFSKKIIPIWQDMLGVRETEVPQMPVHLSSFKRLQIMLRIIreFWTAPK----QMRQ 416 
37528329  390 -LGLVKGRIYYNINNwykglllLPSFQTNKKDMERMMGLEDPVDFIEDKTLSLGDKIKKLPKMGwaLLRLLY----AFRT 464 
253991484 397 -LGLIKGRIYYNINNwykglllLPSFQTNKKDMERMMGLEDPVDFIEDKELSLGDKIKRLPKMGwaLLRLLYa----FRT 471 
295681466 410 -LAFLNGRVYYNLLHwyklsglAPFQDLGRKMMEVQMGVDEPLDLASFAELIRPYKAGSRAGLAsiRAVSGTkfawHFAR 488 
145596653 372 -LGSFHGRVYYNLINwyrlqriAPFYDVNRKLLEVAMGV-DEALPDEIAEGLYPYEFDSAWQRRraRVVTYTtffwKYLR 449 
159038571 372 -LGNFHGRVYYNLINwyrlqriAPFYDVNRKLLEVAMGV-DEALPDEIAEGLYPYEFDSAWQRRraRVVTYTtffwKYLR 449 
296393758 375 mVGLVSGRVYYNINNwyrvlqlAPSFDRKKEDAEKMLGVQNPVEFISDQQLTKREKFRKAQSLLpvAVGWIW----RICV 450 
304309890 478 MNQDVQKFRAMFETVYCSVSRpLLHTLTPGELIAELRRLDRELLQRWTTPIVNDFYVMMMNGRVH--RALVAAGFEQPAV 555 
42524538  455 IQTVVDDFLTTFHKDYDRFRAmPLKRMRGDQLIRVYMDVERNMLGRWKAPIINDFLCMVHFGL----LRKLTTTWLKELD 530 
125717849 414 MRQLEEQFAQIQLEYEASFSP-DADAETLIALVSRLKKDILAHWDITLVNDLYAFVYTGLLKKSR--RGGVVQ------- 483 
157151134 417 LEEQFAQIQREYETSFSP----EADAETLIALVSKLKEDILAHWDITLVNDLYAFVYTGLLKKSS-------------RS 479 
37528329  465 MDQRVELFLEQFKWHAAAIKQsELHTCNSGQLIEKLKYLDEHLLRRWTTPILNDFYVMMFNGRVH--RGLVAAGIENSSA 542 
253991484 472 MDQRVELFLAQFKQHAAAIKRtELHTCNSGQLIEKLKYLDEYLLRRWTTPILNDFYVMMFNGRVH--RGLAAAGIENPTA 549 
295681466 489 LERNVERFRAFFYPVYDEFNAlDYRSLPADAVYAHYC----RFEQALLARWGMMIVLESAIGLSYgvLRRLIKRWIPDAP 564 
145596653 450 MDRDVTRFVAYFYEQYAIFDKrDYAAMPADEVYRAFQDLIRSLNRRWGPMQMLDSTI--LLSMGI--LTMLGRRWLPHAP 525 
159038571 450 MDRDVTRFVAYFYEQYAIFDKrDYAAMPADEVYRAFQDLIRSLNRRWGPMQMLDSTI--LLSMGI--LTMLGRRWLPHAP 525 
296393758 451 RRRSIRNFQRDANAGLLQLRE-RGENARDLAELLAIAEEALRLFDRWAIPMFNDFFLSIQAGRV-----RRMIGRSGAAN 524 
304309890 556 L---QNNLLSGEEGIESTEPTRRLLQMCDYVRKQPPLRNLLEDpstKNSRLLDRIQVLDPV--FYAQCEDFIERYGDRTI 630 
42524538  531 St-iQNDLLAGEGGLESAEPTKALLRLAAKANQNEGLRKLIEEtd--pKEGLEALNQSQYTe-FYKLVLDYLDRFGFRCM 606 
125717849 484 ----AEIAGIEQIESMRPALALQALTAQLKAEENAAIRQAMASes--pAVFLSRQHP------LVKEIVHFIHEFGDRAP 551 
157151134 480 GavqAEIAGIEQIESMRPALALQALTAQLKAEANEEIRQAMASes--pAVFLSRQHP------LIQEIVHFIHEFGDRAP 551 
37528329  543 L---LGDLLSGDEDIESTQPTKVLLKMCQYARQHPELCNLLTLgd--aRTLLTQVRPLDES--FHQQCIDYIKKYGDRTM 615 
253991484 550 L---LGDLLSGDEDIESTQPTKVLLRMCQYARQRPELCTLLTNgd--aRTLLTQVRQLDEP--FYQQCIDYIEKYGDRTM 622 
295681466 565 Dw-lEVAVIGGMNDIESIEPVRRLAALAEAVRSNPRVEALIRN---TPSAETYAALRACGApeIVADIERYLADFAYRSN 640 
145596653 526 Ew-lTWAAARPGADVESAEPARELAALAATVKADDELRHLVTE---TDPAAIPGALAAAGHttLLAAVDAYVEAHGYRSP 601 
159038571 526 Ew-lTWAAARPGADVESAEPARELAALAATVKADDELRRLVTE---TDPAAIPDALAAAGHttLLAAVDAYVEAHGYRSP 601 
296393758 525 TdetVAGLLAAHEAIESIEPTLQLMRIALQIQRDERWAATLNDae--pLSALEKLCELAPQ--IGAQLDVFVERYGDRCM 600 
304309890 631 GELKLESVTLRQDSSFLFAVLRNYLARTDLTPETLAANEARFRHEAE-AEAFNAVRKQL--GVRALKRFQKHLSKLRDAI 707 
42524538  607 SEMKLEEIDLLTDPSYLFVCLKNYLKSGQVEAHDDTHEKNLRQQAEAkVAGHLTGIKQ--------KIYFWVLKHARKAV 678 
125717849 552 EELKLETPTFRTHPERLLKLLLQMCQQEEKKLAPQKLEEEEQKSGWW-TN--------------------FLRKRAMTGV 610 
157151134 552 EELKLETPTFRTHPERLLKLLLQMCQQEEKKLAPQKLEEEEQKSGWW---------------------TNFLRKRAMTGV 610 
37528329  616 GELKLETITLKQDPSFLFLILKNYLAI--DTLTPETLSSRERKLRTQ-AENTAFQQIQQrlGSKRMNTFKKNLQKLRQAI 692 
253991484 623 GELKLETITLKQDPSFLFLIIKNYLAI--DNLTPETLSSRERKLRTQ-AENTAFQQIRErlGSKRMGTFKKNLQKLRQAI 699 
295681466 641 NELKLEEPDLREDPGVLFDMLKASLAHGAATIDRTA------------TETRIDALLHErlGPLQRWLFARARSRVRAAI 708 
145596653 602 DELKLEVPDLHEDPSSLYLMLRDALQAPPETTSGDSAQEYLDQHLRG-PRRWIYELTR---------------RKVSRSL 665 
159038571 602 DELKLEVPDLHEDPSSLYLMLRDALQAPPETASGDSAQEYLDQHLRG-PRRWIYELTR---------------RKVSRSL 665 
296393758 601 GEQKLETISLRQDRSFLAKILRNYIAD--PDLDPVAFEKSQHARQKKfEEQVLSGLPRF-----RRWRLGRVLASARDAV 673 
304309890 708 RNRENMRLARTRMFGLYRELFLELGQQWAMHGLLSEPRDIFWLSVEEIYALNDGRaVQTNllPLVAARKEEYAGWESRQv 787 
42524538  679 KNRENTRFARTRIYGIARTIFQTIGEDLASLGALENSRDIFWLTIEEVFGIYNGTlPSFDlkAFVELRKKDYARFTEET- 757 
125717849 611 KYRESSRLNRTRIYGMMRQIFRTLGQQLNEQGLLATPDDVFYLTKEELFDLTRKPrDVS---GLIAERREKLEADKELPt 687 
157151134 611 KYRESSRLNRTRIYGMMRQIFRTLGQQLNKQGLLATPDDVFYLTKEELFDLTRKPrDVS---GLIAERREKMEADKELSs 687 
37528329  693 RHRENMRFTRTRMFGLYRDIFLQLGQAYALEGILAEPRDIFYLTLEEIYSGYEGTaIQTQlePLVAMRKQEYANYETED- 771 
253991484 700 RHRENMRFTRTRMFGLYRDIFIQLGQAYALEGLLAEPRDIFYLTLEEIYSGYEGTtVQTQlkPLVAIRKQEYASYETED- 778 
295681466 709 RARETVRFCRSRAFGVARRMFRAIGEGLAADGVLATGRDIFHLRLDEIRGCFEGTvSHRElrPLIEQRKRDDASYRAMDd 788 
145596653 666 AARERLRFCRTKAFGSAKRMLRALGRHLQQVGAIERFEDVFLLRLDELAGAYEGKiAHDElrDIVAARRRTQDRQATMSa 745 
159038571 666 AARERLRFCRTKAFGSAKRMLRALGRHLQQVGAIERFEDVFLLRLDELTGAYEGKiAHDElrDIVAARRRTQERQATMSa 745 
296393758 674 RSRESMRFTRTRLIGVGRLLYTKVGQLLHAAGCLDDPRQVFYLSMDEISAFAEGRaVTTRlaELARLRAAEFAEYEDEE- 752 
304309890 788 pEPAHHFHThdtvsfFNDYTYPFAEPEsSD-----SA--ELIGTGCYPGIVDAKVRLIFSPDDELALDGQILCTVRTDPG 860 
42524538  758 -DPRVMTRG------AVYWNNTFIKEEdLSqvsseTGdwDLKGLPCCPGVLEGVVKVIINPSDNLDLNGEILVTARTDPG 830 
125717849 688 fSRYVFV--------GQVFEKYLKPQNrTSshntcNQ--ALQGIGCSPGCVKAQVLVVEDVQEIESAQDRIIVTKMTDPG 757 
157151134 688 fSRYVFA--------GQVFEKYLKPQNrTSshntgNQ--ALQGIGCSPGCVKAQVLVVEDVQEIESAQDRIIVTKMTDPG 757 
37528329  772 -EPAHHFFIrgslyqQQDYSYPYQEQQ-APt---dSS--MLQGIGCYPGQVETTIRLIKNPQDEMSLAGQILCTVRTDPG 844 
253991484 779 -EPAHHFFTrgslyqQQDYSYPYQEQQ-LPt---dSS--VLQGIGCYPGQVETTIRLIKNPQDEMSLAGQILCTVRTDPG 851 
295681466 789 lPPRFVTHGpvaawlGKPANLAALHAApAQa---aGA--TLRGTPCSPGFAEGRAKVVREANEF---DGGILVTYRTDPG 860 
145596653 746 -PPRFRTYGapy-weGNLEAAGWSVGR-ATrt--gVG--ELRGTPSSPGVTTGRVVVTTRPQDV---NGGIIVAYSTDPG 815 
159038571 746 -PPRFRTYGapy-weGNLEAAGWSVGR-ATrt--gVG--ELHGTPSSPGVTTGRVVVTTRPQDV---NGGIIVAYSTDPG 815 
296393758 753 -PQNQFVTF------GSPYTGRRSTPA-APrassdGQ--VLRGVGCCPGVVEGQTQVVLSPLDDLNVRGKILVTVRTDPG 822 
304309890 861 WAPLFPTAGGILVERGSTLSHSAVVARELGIPAIVGIPDITRRVRDGERVIMDGAKGTVRRV 922 
42524538  831 WVPLYPSISGLLVERGSLLSHSAIVAREMGIPAIVSIPGLTKKLKTGMRVRIDAKAGTIKIL 892 
125717849 758 WVYLLTQAKGVIAEQGSLLSHTAIISRELGIPSIVNVRGACSHLQNGDWIEMDGLAGKIRLI 819 
157151134 758 WVYLLTQAKGVIAEQGSLLSHTAIISRELGIPSIVNVRGACSLLQNGDWIEMDGLTGKIRLI 819 
37528329  845 WAPLFPTAGGLLIERGSTLSHSAVVARELGIPAIVGIPAVTQILKDGDRVRMDGATGTVVRL 906 
253991484 852 WAPLFPTAGGLLIERGSTLSHSAVVARELGIPAIVGIPAITQILKDGDRVRMDGATGSVIRL 913 
295681466 861 WVPVFASATGLLIERGSPLTHAAIVAREIGIPTVVQIPGLTTRVQSGMQLKVDGHSGVIELP 922 
145596653 816 WVAALPSATGLIIERGSPLTHVAIVARELGVPTIVKAKGATQELETGMTVRMDGGTGTITIL 877 
159038571 816 WVAALPSATGLIIERGSPLTHVAIVARELGVPTIVKAKGATQELETGMTVRMDGGTGTITIL 877 
296393758 823 WGPLFPGLAGLLVERGSTLSHSAVLARELGIPAVVGVPGLMRGITGGERVRLDGGTGTVWRL 884 
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