Conserved Protein Domain Family
Lipocalin_5

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pfam13924: Lipocalin_5 
Lipocalin-like domain
This family includes domains distantly related to lipocalins. However, they do contain the important GXW motif in the first strand. The protein in this family include aln5, which is involved in biosynthesis of alnumycin. The family also includes the ZFK protein from Trypanosoma brucei which is a protein kinase. This domain is at the C-terminus of that protein. The domain is also found as the C-terminal domain in StiJ a protein involved in producing stigmatellin. This domain has been assumed to catalyze a final cyclization reaction.
Statistics
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PSSM-Id: 464043
Aligned: 24 rows
Threshold Bit Score: 120.893
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q4Q898                  1066 HGTWRVVS---IEVHAVDDGR--VIFPWGGDVSGVLVYTTGGRFSLQLTSSARRPvg---pVQRVTQLSKEDLCD--TYC 1135 Le...
PRJNA326509:BAY22_03225    7 IGSWSLIS---QHFILPDNS---IHYPMGQNMLGRINYEKQGTMAAQLYRGDRAKf----tTEDWLQGSDSEIKN--AFL 74  
EEA24144                   9 YGVWKLVGynlYHAEDPSGKS--ILQPLGESPLGRIMFLPSKYMHVSMTSPGRAEnm---aSPAWYLATEAELAY--AAK 81  
Q0UF46                    40 IGTWHLLS---LHFCLNEDATeiIGEPAGPNPLGRITFTREGYMSALI--------------TDPRIAHPIDKPW--IAM 100  Pa...
WP_020460574             105 LGVWELLA----FQRLMDGQV--IGDALGPSPVGRLTYESGGYVSALLMMHDRPWr----eGRAFLNAPEAERGA--AAL 172  Fr...
Q0UA57                    40 AGTYTLIN---TTSALNGVSI--PDAAYGTAPIGILIYTSTGWMSATITATEPELrppqliFPFQANDTDADWAL--VGK 112  Pa...
XP_001934995              37 AGTYSLMN---TSSTFNNVPV--PDSTYGKNPVGLLIYTAAGFMSATITATEPEFrpn-vsFPFKPNETDAQWAQ--VGR 108 
Q2JEB1                    49 VGAWKLVS---FIVTDRNGII--LSMPMGTQPSGLVIYAADGHMSAHLRDPQRRTss--asVSEFMNSSQVDAESiaMNH 121  Fr...
EED47650                  12 IGTWVLLE---YRTESLKSKQ--VKWPFGSSPKGILIYSPAGYMSAQVMRPGTPQh----eGQEFLSGTDEELAV--AMR 80  
Q0CAL3                    76 IGSWKLVK---FVSEPVNGTEpcNYFPFARGAQGFIIYTSDGHMPVHLMRPGAPRc----tSAGFLEGSKDKLAL--SMK 146  As...
Q4Q898                  1136 SYVASFGRFhlfpsSMDDGc-------gVVRHFSEGNLCPNLMLATTVFQYCMH-TeplhpSA---TKGESayKDSGKHA 1204 Le...
PRJNA326509:BAY22_03225   75 TALTYFGRY-----HIDEEq-------gIVTHTVEGCLFPNWVGNQQIRHYQFE-E-----DR---LTL----RTPPLQM 129 
EEA24144                  82 YVTMYCGPF-----QIYEEdg-----etRVDTHVEVSLDQTWIGTHQVRRVELSyE-----NEksiLTLTPlqEFSLASF 146 
Q0UF46                   101 ALSAYCGKY-----KVSEKng-----elQIATQVEISLDPNWIGSKQVRNVRLG-EvkdgkQT---LVIT---PTESFTL 163  Pa...
WP_020460574             173 RFIGYSGRY-----GLRGR---------TVVHHVDISLYPDHVGTDLVREVDWS-G-----ED---LVLL---TEERRTP 226  Fr...
Q0UA57                   113 HSIGYAGPL-----RLSDAipanlthgqVFHGPLTVANVPSWKGQNQRRNFTV-------------IEEGGetL---LRI 171  Pa...
XP_001934995             109 HSIGYAGPL-----SVNMElpangtsgqVFHGPLTVANVPTMVGDRQRRNYTVI------------DRMEEgkVVKYLRI 171 
Q2JEB1                   122 PYIGYCGTY-----CLEDD---------QVIHHVQVASVPEWIGGNQVRNFALR-E-----NV---LTL----CCPAKWD 174  Fr...
EED47650                  81 HYLAYSGRF-----TVPDMaste-nstrRVIHEVEMSSYPNWIGTTQERVVHIK-G-----DI---LELS---TVHPLVI 142 
Q0CAL3                   147 HYLAYAGRF-----DVRETdg-----gaLLRHHILVSSYPDWLGTVQERRALLE-G-----DV---LRLE---TVNILEK 204  As...
Q4Q898                  1205 GTASSTa----AAATSARR 1219 Leishmania major
PRJNA326509:BAY22_03225  130 NNSSLV-----GVLIWQKV 143 
EEA24144                 147 SNKCQDgtmtiARLVWEKI 165 
Q0UF46                   164 ANGISGw----AVLTWVKM 178  Parastagonospora nodorum SN15
WP_020460574             227 SGRLMR-----ERLVWCRA 240  Frankia sp. EAN1pec
Q0UA57                   172 GSERGGgy--tGVLWWRRV 188  Parastagonospora nodorum SN15
XP_001934995             172 GSERGGgn--rGFLWWKKI 188 
Q2JEB1                   175 GSGIRL-----PYLTWERI 188  Frankia casuarinae
EED47650                 143 SGIEQR-----SFLTWRKL 156 
Q0CAL3                   205 EGFQQR-----WVLTWKKT 218  Aspergillus terreus NIH2624
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