Conserved Protein Domain Family
Ly-6_related

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pfam06579: Ly-6_related 
Caenorhabditis elegans ly-6-related protein
This family consists of several Caenorhabditis elegans specific ly-6-related HOT and ODR proteins. These proteins are involved in the olfactory system. Odr-2 mutants are known to be defective in the ability to chemotax to odorants that are recognized by the two AWC olfactory neurons. Odr-2 encodes a membrane-associated protein related to the Ly-6 superfamily of GPI-linked signaling proteins.
Statistics
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PSSM-Id: 399524
Aligned: 14 rows
Threshold Bit Score: 127.458
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003375481  42 CASYELRAYWYH--LQAWYNTPKNFTDRCVTMNRRdcQHIALESCP--SQCITLRQQKTIAGHTVGYH-VIRGCLTSLFR 116
XP_020303091  35 CMSPLYEELFKDgvMSRYFYEPRNFTSQCNEPMRP--SNIGLVACK--SICLTLTQDFVVMGRNTGKKlTIRGCAVSISR 110
1_pfamImport   1 CMSTYYEQLFNGr-VQNIFNEPKNFTRHCDDPAAP--HLLEAVACR--TICLTITHDLVVFGQRTGQIvTMRGCAISIAK 75 
Q8T3D0        43 CASFVYLPLWSQ--LMHHYYPPKNFTDRCWQPD----SGIGLVPCS--SACFTLVER--IDDVSEQHG-VIRGCMDRLLL 111 Caenorhabditis ...
EGT34036      30 CMSKLYEAVWPS--LSHIYKKPRNFTDDCDDERISe-GRVPIVHCP--TICVSLFEQPNIAGVRIKG--YIRGCMSDVLI 102
NP_001256848  51 CMSLSYQTSWKY--LQTTYIYPKVFTDRCRDPNSE--RGMPTVMCG--SVCVSLMEPDVEAGVFIGFK-HIRGCLDRVLR 123
NP_001293772  37 CMSKYYGALWRFagYTRIYQEPGLFTDSCRDPQARg-SDVPSTICKekTNCVTMVEDLKIGTGAKG---YIRGCWGSVFL 112
NP_001024089  30 CMSPYLEDHYPY--ISHLYRKPLSFDTHCDKHSLEt-SYLYSKNCS--DMCVTLRINDVVGGRRRHG--YMRGCLSDL-- 100
3_pfamImport   1 CMSEDFLLHWPY--LDEVYYRPLNFTDHCFKMTPS--ANIGTMPCSh-SMCVTVIEPRILAGQHIGNN-IIRGCFSGVFK 74 
XP_001899418  39 CMSEAFQKHWSF--LSQIYFMPMNFTDYCYDMPPK--VHIGVTTCSh-SLCVTVIEPRILAGHHIGNN-VIRGCFSSVFK 112
XP_003375481 117 WNILdtsQISASLMKPRDFCYNLRLS--QILPSYgsgvkGESDQlVRLCVCHGDRCNS 172
XP_020303091 111 HGFF---NRTMVLFDRYDMCRDVKAS--DLFRYE-----SDSQT-IRVCSCFGDRCNV 157
1_pfamImport  76 KGIH---NHTLAMFDRYDICREMNAA--DLFRTEyg--rGESQR-IKVCSCLGDR--- 122
Q8T3D0       112 FGLDddvRNILSAYENQRVCRHTDRKllRLFPLSgq-------tdVTFCSCNGDFCNe 162 Caenorhabditis elegans
EGT34036     103 SGFNqtiVTWYRWMHRDS-CRPYRKK--ELFKLGge--sTDDST-IDVCTCYADHCNG 154
NP_001256848 124 HGFNqsaLRTHR-FHQNNHCRTLSRS--ALFNPArqtdpPALGD-VQLCSCYGDRCNS 177
NP_001293772 113 FGFNr--TGTVGALAEHSFCHTFNLT--QLVSgg----rPEESS-INVCSCRGPLCNG 161
NP_001024089 101 HGYN---HSLIRTLAERQGCLDTTAR--ELFLPTaqrqeLEPSR-LSLCACHNNLCNF 152
3_pfamImport  75 YGST---PKSQSQQVLDTSCSRMPAH--KLLPPRla-arSSNRT-VELCWCAGQLCNY 125
XP_001899418 113 YGPT---PSNDGFSTSDTSCSRMPAY--KLLPPHla-rrASNRT-VELCWCFGQLCNd 163
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