Conserved Protein Domain Family
PRK05500

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PRK05500: PRK05500 
bifunctional orotidine-5'-phosphate decarboxylase/orotate phosphoribosyltransferase
Statistics
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PSSM-Id: 180119
Aligned: 12 rows
Threshold Bit Score: 812.376
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
113474256   1 MNFFDKLLTSIEKNQSLLYLELDPNPESLPkqaeGKNipakylllkhpekDNQELIQDWWEWLHFLITQTEKYVCAYKLS 80 
17230437   24 MIFFDKLHQNISQNQSLLFVGLDPNPEMMP----GRY-------------SSQDIIDGLWDWLQFIIAETADFVCAYKPT 86 
37520648    1 MNFFDKLDKAIAQQGSLLFVGLDPNPEMLP----ERY-------------GRTASIAALRDWMRALVEQTAASICAFKPT 63 
75907180    1 MIFSDKLHQKISQNQSLLFVGLDPNPEMMP----GRY-------------SSEDIIDGLWNWLQFIIAETADFVCAYKPT 63 
113952716   1 ------MLRSWADLRGL---------------------------------NGRSLLSQARSWCKSVIEETADHVCAYKPS 41 
166365579   1 MNFFQKLNHAISQNQTLLVLGLDANPEMMP------S-------------TPGELIVNLEQWLKFIIDETAPFVCAYKPT 61 
170077235   6 ATFTEKLTGAIAAQKTLLVAGLDPNPEMLP----DSL-------------RTGDLIQNLKTWLLGIIDQTQDLVCAYKPT 68 
186683720   1 MNFFDKLNRSILQNQSLLFVGLDPNPEMMP----VRY-------------ESEELIAGLEKWLQFIIAETADYVCAYKPT 63 
172035418   1 MNFFEKLTQRITNYNTLLILGLDPNPEMMPqdedSYQ-------------GQQSLIIALESWLKWIIEQTSGLVCAYKPT 67 
218247100   1 MSFFEKLTQAITYHETLLVVGLDPNPEMMLqyhyNDC-------------SPDSLKKQWSTWLKSIISETMGSVCAYKPT 67 
218438647   1 MSFFEKLETAIAHNQSLLVVGLDPNPEMMPfseeIGD-------------NSDVLIPRLWEWLNLIIEETSDLVCAYKPT 67 
257060170   1 MSFFEKLTQAITYHETLLVVGLDPNPEMMLqyhyNDC-------------SPDSLKKQWSTWLKSIISETMGSVCAYKPT 67 
113474256  81 LGYYQSFGIPGLQLLQQTLKTIPSEIPIILDAKHSDLKTSTVFAQSIFADLQVDACTILPYTGFDLVVPFLLYPGKAVFL 160
17230437   87 LGFYEALGVPGLELLQKTLAAIPSHIPIILDAKHSDLNTSTIFAKTVFTQWGVDAITLSPYTGQDHVAPFLVYPDKAVFI 166
37520648   64 LGFYQALGPAGIDLLLEVLEWIPPHLPVILDAKHGDLNTGTQLARTFFEDWGVDAVTINPFAGQDAVAPFLLYPRKGVFV 143
75907180   64 LGFYEALGVPGLELLQKTLGAIPSHIPIILDAKHSDLNTSTIFAKTVFTEWGVDAITLSPYTGQDHVAPFLVYPDKAVFI 143
113952716  42 LGFYQAMGSAGVELLLEVRELLPPDLPLIIDIKHGDLNSSSAIAAYLFQSLHADAVTLNPFAGQDIAAPFLLYPGKGVFI 121
166365579  62 LGFYQALGSAGLELLQRILTAIPPHIPVILDAKHGDINTSSVLAETIFKTWQVDAVTLNPYSGQDHVAPFLVYPEHGAFI 141
170077235  69 LGFYQALGVPGLQLLETVLAHIPPDIPIILDAKHADLNTSSLFAQAIFEAWQVDAVTLSAYPGQDHVAPFLLYPDKGVFL 148
186683720  64 LGFYEALGIPGLELLYKTLAAIPAHIPVILDAKHSDLNTSTIFAQTVFTEWQVDAITLSPYTGQDHVAPFLVYPEKAVFI 143
172035418  68 LGFYEALGSEGLDLLLKVIQAIPDDIPIILDAKHGDINTSTIFAKTIFEQWNVDAVTVSPYAGQDHIAPFLVYPDRGVFV 147
218247100  68 LGFYQVLGALGLELLSEIIAEIPPDIPIILDAKHGDLNTSTIFAKAIFEQWKVDAVTVSPYSGHDQVAPFLVYPDKGVFV 147
218438647  68 LGFYQALGIKGLELLLKVLDAIPKTIPIILDAKHGDLNTSTVFARTIFEQWQVDAVTLTPYAGLDHVASFLVYPDKGVFI 147
257060170  68 LGFYQVLGALGLELLSEIIAEIPPDIPIILDAKHGDLNTSTIFAKAIFEQWKVDAVTVSPYSGHDQVAPFLVYPDKGVFV 147
113474256 161 LCATANASAGVLQQYPNQEQPLYLKLVVEAQRWATPEKLGFEVGIM-PDILGKIRQVAPERLILIQGDIAEENDinnpqk 239
17230437  167 LCSTSNPGAEALQQYPTRESPLYLQVVQESKNWGTPEQLGLEVGTTnAEVLARIRQVAPERMIMVRSIWAEGGN------ 240
37520648  144 LCHTANPAAQAMQAHPGQQPPLYQQVVREARGWGLPEQLGLEVGTVrPEILARVRAAAPERLIMVRSLWAAPPGa----- 218
75907180  144 LCSTSNPGAEALQQYPTRESPLYLQVVQESKNWGTPEQLGLEVGTTnAEVLARIRQVAPERIIMARSIWAEGGN------ 217
113952716 122 NCHSSNPAAHDLQHHPNDHNPFYLKVVRESQSWGTPEQLLLEVGTSdPAILADVRQAAPERFVMLRSLWGEEGN------ 195
166365579 142 LCHTSNQGAINLQEFPSCDNPFYLQVVKEACTWGTPEQVFLEVGTTqPEILKKIRNFAPERLILLRSIWEDKSK------ 215
170077235 149 QCRTSNPGAFPLQNYPDPQRPFYLHLIQEIKQWGTPEQLFLEIGGDrPAVFRQVRAIAPERWILARSIWQRSEN------ 222
186683720 144 LCCTSNPGAEALQQYPTNESPLYLQVVKESKTWGTPEQLGLEVGTTnAEVLALIRAIAPERIIMARSIWAKGGN------ 217
172035418 148 LCHTSNPSAVILQEYPTDEAPFYLEVIKEARTWATPEQLFLELGTTnLAVIKKTRSLAPERLLLLRSIWSKGND------ 221
218247100 148 LCHSSNPGAIALQEYPTPETPFYLQVVKEAKMWGTIEQVLLEVGTTdVEVIKKIRSIAPERFILMRSIWSQKNQ------ 221
218438647 148 LCHTSNPGATNLQEYPTADNPFYLQVVREAQTWGANEQIFLEVGTTkPEVINNIRNCATERIILLRSIWEQKHN------ 221
257060170 148 LCHSSNPGAIALQEYPTPETPFYLQVVKEAKMWGTIEQVLLEVGTTdVEVIKKIRSIAPERFILMRSIWSQKNQ------ 221
113474256 240 LNQLLAAGLNINGEGLLLPIPPKLLGTAEPKTAIKSLISTINEQRLKMVKGSPTCELWLPDICFLQHQPHR--------- 310
17230437  241 LNRILEVGLNTDGNGLLIPVPQDMLASANLSKEIQSLRAEINQVRDITVRDVASCSVWLPDVFTVKQHPLH--------- 311
37520648  219 LASMLAAGLDAAGAGLLVPVPQECLGADTPGLSVAALRCEIEAIRTVPGDVPSSCTLWQPDVCLIETDRLL--------- 289
75907180  218 LNRILEVGLDTDGNGLLIPVPQDMLASANLSKEIQSLRAEINQVRDITVRDVSSCSVWLPDVSTVNQHPLH--------- 288
113952716 196 LQCLLKNGLNKMGDGLLIPLPQNLLNGNNINEQTSTLKGRINRIRDQHLQERAHTDAIHPEQCRIWPHSDQsnqddsitt 275
166365579 216 FSELITVGLNSHGEGLLIPVPQDFLSQPDLGAKVKDLREEVNKIQQNHQQESSGDDTWTANVCLLKQHPHQ--------- 286
170077235 223 LEEIVHQGLNSNGSGLLIPIPNDDLSQTDCRQPVAQLRQKIEDIRQRYTPSNARCDLLQVPTNFPAAHPQA--------- 293
186683720 218 LRQILEAGLNDNGDGLLIPVPQDMLGNTQLSEEVESLRAEINQLKTEIIHENSTCSVWFPDVCFLNQHPYQ--------- 288
172035418 222 INDILKAALTPMGDGVLIPIPQDFLKSSDLQEQVKNLNEDINQYRQTIIQNPQNCDLWSPNVCLLNSHPHQ--------- 292
218247100 222 LETILTAGLNSNGDGLLIPIPQDFLKADHLKEQVKTLNQEINRTRNQIMSQQNSCQLWTSDVCLFNPHPYQ--------- 292
218438647 222 FKQILTAGLTVEGNGLLIPVPQDLLSHPNIKQEINALREDINQIRTGVKKEELREQLWTPNLCFLEQHPHQ--------- 292
257060170 222 LETILTAGLNSNGDGLLIPIPQDFLKADHLKEQVKTLNQEINRTRNQIMSQQNSCQLWTSDVCLFNPHPYQ--------- 292
113474256 311 --------------DLILQLYNLGCIIFGDHVQASGAIFPYYIDLRKIISIPQIFHKIVTAYAEIIQNLEFDRIAGIPYG 376
17230437  312 --------------DLILQLYDIDCIMFGNFVQASGAVFPYYIDLRKIISNPQVFNQVLSGYENIVKNLTFDRLAGIPYG 377
37520648  290 --------------DLALQLFDTGCILFGEYVQASGAVFPYYIDLRRIISNPQLFQQVLLAYAEILSTLSFDRIAGIPYG 355
75907180  289 --------------DLILQLYDIDCIMFGNFVQASGAVFPYYIDLRKIISNPQVFNQVLSGYENIVKNLTFDRLAGIPYG 354
113952716 276 vredgvkpidqdlwDLVIDLYDIRCLLFGEFKQASGEIFNYYIDLRQIISDPALFHRVLDCYAQVLRPLRFDRIAGIPYG 355
166365579 287 --------------DLILQLFDIGCLMFGDYVQASGETFSYYIDLRKIISNPNIFQQVIEAYGEILKTLTFDRIAGIPYG 352
170077235 294 --------------ELIVQLFDLGCLLFGEYVQASGATFSYYIDLRKIISNPQVFNQVLNAYGAIAKNLKFDRIAGIPYG 359
186683720 289 --------------DLILQLYDIDCIMFGSFVQASGAIFPYYIDLRKIISNPQVFNQVLTAYEDILKNLNFDRLAGIPYG 354
172035418 293 --------------DLILQLYDIGCLLFGEYVQASGATFSYYIDLRKIISKPQLFHQVLSAYADILKSLNFDRIAGIPYG 358
218247100 293 --------------DLILQLYDIGCLLFGEYVQASGATFSYYIDLRQIISNPQIFHQVLRAYADILDQLEFDRIAGIPYG 358
218438647 293 --------------NLILQLFDIGCILFGEYVQASGATFSYYIDLRPIISNPQLFHQVLQAYAEILETLTFDRIAGIPYG 358
257060170 293 --------------DLILQLYDIGCLLFGEYVQASGATFSYYIDLRQIISNPQIFHQVLRAYADILDQLEFDRIAGIPYG 358
113474256 377 SLPTATGLALHLERPMIFPRKEVKAYGTGRLIEGHFQPGEKIVVVDDIMITGNSVMEGAEKLKSVGLKVEDIVVFIDHER 456
17230437  378 SLPTATGLALRLNCPMIFPRKEVKAHGTRRLIEGNFRTGEVVVVVDDILISGKSVMEGADKLKSAGLNVHDIVVFIDHEQ 457
37520648  356 SLPTATGLALHLNRPLIFPRKEVKAHGTRRAIEGTFYPGETVVVIDDILITGNSAVEGARKLQSVGLVVRDIVVLIEHGP 435
75907180  355 SLPTATGLALRLNCPMIFPRKEVKAHGTRRLIEGNFHPGELVVVVDDILISGKSVMEGADKLKSAGLNVHDIVVFIDHEQ 434
113952716 356 SLPTATGLSLQLHKPLIYPRKEVKAHGTRRMVEGEFKKGETVAVVDDILITGGSVMEGISKLESSGLNVRDVVVFLDHGG 435
166365579 353 SLPTATGLSLLLNHPMIFPRKEVKAHGTRRVIEGNFQVGETVVVVDDILISGKSAIEGAAKIKSAGLLVNDIVVFIDHGG 432
170077235 360 SLPTATGLALKLNYPMIFPRKEVKAHGTRRVIEGHFEPGETILVVDDVLITGKSIVEGAKKLESAGLTVQEMVVLIDHEA 439
186683720 355 SLPTATGLALRLHCPMIFPRKEVKAHGTRRVIEGNFHPGETVVVVDDILISGKSVMEGAGKLESAGLNVNDIVVLIDHEQ 434
172035418 359 SLPTATGLSLMLHHPMIYPRKEVKAHGTRRLIEGNFKAGEKVVIVDDILITGKSVKEGAEKLTSSGLVVKDIVVFIDHEQ 438
218247100 359 SLPTATGLSLMLHHPMIYPRKEIKAHGTRRLIEGEFNPGEKVVLIDDILITGKSVIEGAEKLQSSGLIVKDIVVFIDHEE 438
218438647 359 SLPTATGLSLLLHHPMIYPRKEVKAHGTRRPVEGTFHPGEKVVVVDDILITGKSAMEGAEKLKSVGLNVEDIVVFIDHEE 438
257060170 359 SLPTATGLSLMLHHPMIYPRKEIKAHGTRRLIEGEFNPGEKVVLIDDILITGKSVIEGAEKLQSSGLIVKDIVVFIDHEE 438
113474256 457 ----GVKDKLQDHGYLGHSVLTLTEIAQTLYESNKINYEQFNILKNH 499
17230437  458 ----GVKDKLQANGYRGHAVLTISEITSVLHQAGRINDEQFLALTAE 500
37520648  436 ----EASAFLQSQGYNAYAVLPFERIARTLHQAGRIDDSQYAALGED 478
75907180  435 ----GVKDKLQANGYRGHAVLTISEITSVLHQAGRINDEQFLALTAE 477
113952716 436 ihdlRAKQRLQSHGVKLQAVLTLDTISHVLETSDRISPDQAQELRHT 482
166365579 433 ----PVKDKLRSHGYQAYSVLTLAEITDTLYEAGRLTEAEYSCFLNR 475
170077235 440 ----GVKDRLQAQGYQAHAILTISEITETLFQAGRINQSQYDCLVSH 482
186683720 435 ----GVKDRLQQNGYRSHSVLTISEITNTLYQAGRINEEQFLAFAES 477
172035418 439 ----GVKDKLKKEGYQAYSVLTISEITETLYEAGRINEQQYKSFFKH 481
218247100 439 ----NVKDKIESYGYTAYSVLKISEITETLYAAGRINQEQYQRLS-- 479
218438647 439 ----GVKDKLKNNGYNAYSVLSISEITQTLYEAGRINEQQYHSLTEK 481
257060170 439 ----NVKDKIESYGYTAYSVLKISEITETLYAAGRINQEQYQRLS-- 479
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