Conserved Protein Domain Family
RNF220

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pfam15926: RNF220 
E3 ubiquitin-protein ligase RNF220
This family represents the central region of the E3 ubiquitin-protein ligase RNF220.
Statistics
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PSSM-Id: 464946
Aligned: 7 rows
Threshold Bit Score: 289.868
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q170U5        25 PRSDPLCCPICGVTLRTNEIDQHFALEVERLDKILKPRRNLhcptggypmgtdmasvgpgTSTSRATATSSG----AGMA 100 yellow fever mo...
EEB14588     216 FSLDPTSCPICGIMVLLGEAEAHFFKELEKLTHLTTINRDK-------------------KYAIEKYRDVQScfptFGNS 276
ETN60597      47 TRLDPMCCPICGITLRPQEIDQHFAVEVDRLERILKPKRHLgggsgdgg----sgvagpsSSTAGSGSSNGNgetrSHSS 122
XP_001862905  19 QTSDPLCCPICGVTLRSSEIDQHFALEVDRLDKILKPKQNLtgqcf---------gggpsSSAAAVPGTSSG----S--S 83 
EFN86969       7 FPSDPSCCPVCGVTVRPQELEQHFAQELDRLYKV--------------------------SSATSRPRPSRStlppTHPQ 60 
XP_011443070 184 ldGQSPCCPICGLTLRNGEVDAHFALEMDRLERIVRSGR---------------------RSRDATPQGRKTltspSGHR 242
XP_015210807 222 YDSQAPICPICQVLLRPGELQDHMEQEMDRLTQLHISKNPA-------------------HKDCVTPGTPKSillsVHIK 282 spotted gar
Q170U5       101 NGNRSLEDNGEPGPGSNPDECWGTYQKIKNNRQARLKMK---------------------------------TR-----K 142 yellow fever mo...
EEB14588     277 SSSSSSDDNGSLTDSGVPRGRWETYQRIKSNRLSRLRIK---------------------------------NR-----K 318
ETN60597     123 NGHD--EQR---GSVVAPDECWGTYQKIKNNRQARLKLK---------------------------------SR-----K 159
XP_001862905  84 NGH---AENGESSTVVNPDECWGTYQKIKNNRQARLKMK---------------------------------SR-----K 122
EFN86969      61 DHPHGSMLHAPSAADGTPQGRWETYKRIKANRQVTIRVK---------------------------------NR-----K 102
XP_011443070 243 QRKDSPSIEAAS------QSRYDTYMRIKCNRQSRLSAR---------------------------------SRn---rK 280
XP_015210807 283 REGESPTASPLSSEDIHHSDRYQTFLRVRANRQTRLNVDdlcwcrryaresgktvplrphngapfvpccprhARigkmkR 362 spotted gar
Q170U5       143 RKTED-NVCPVCNKSVS---EEITTHveaclrks--etngsgsnGRINDSDDDDASIDVE-G--ESYEVYEWAGQTRIRT 213 yellow fever mo...
EEB14588     319 KKNGD-PVCPVCNEKIQgsvENINLH------------------HTDEAEEDEDENIDVEgDs-EVYGEYEWTGRHLIRA 378
ETN60597     160 RKPED-NVCPICNKVTL---EDITLHvesclrkse-gqrngiedADDDDDDDDDASIDVE-E--VTYETYEWAGQKRIRS 231
XP_001862905 123 RKTED-NICPICNKTVL---EELTVHvdaclrksetngsnggttSRGTDSDDDDASIDVEgG--ENFEVYEWAGQTRVRT 196
EFN86969     103 RKADE-TSCPVCSERLSgtpEELNQHvdrcln------kqnngnPAGQNATLDEEEVDVEgDa-ETFDEYEWAGQRRVRA 174
XP_011443070 281 KRPDE-TVCPVCNDRVVgspEELTAHvevcl----------------krksEEDEPVDVEgD--EQCEEYTWAGQTRIRA 341
XP_015210807 363 RKPEDgQRDGACGA--------------------------------------EEDSAEMEgEngNRFEEYEWCGQKRVRA 404 spotted gar
Q170U5       214 TTMVhqSGAFPsTAVRVTNAE------------DTDDELN--VDGDETQIYGPPQYSERDVVYPVAEQRCKDS----YLR 275 yellow fever mo...
EEB14588     379 TTFL--VGGFT-AGLLTSDTSsssnnhhhqqplEKNERIPnlIEGEDSNCVTPAQFSDTDTSYNADDDNVKDKggkhREK 455
ETN60597     232 TTLLs-PTALAgVAVRVTNAD------------DTDDELN--VDGDESQVYGPPQYSERDVIVSSDGSASG------ALR 290
XP_001862905 197 TSSLhqSGSFAsTTVRVTNAD------------DTDDELN--VDGDETQIYGPPQYSERDIIYPIADNRYKDS----YLR 258
EFN86969     175 TSML--VGGFSaAGLATSSSNrsgpgggpgnqeDEDVDLV--VDGDDAAEFGPAQYSEADVVAPRIDGTLREQkerdALR 250
XP_011443070 342 TTLL--QGGLGgSGFQTYSSKrh---------iEEDIDLD--VDGDDSKQYGEPQFSEADII-PCSSEEPGEDkeraALR 407
XP_015210807 405 TSLL--EGGFRgSGFVTCNSKen---------hDSDADLD--VDGDDTLEYGKAQYTEADII-PCSGEEPGEAkereALR 470 spotted gar
Q170U5       276 GLVMA-NEPITV 286 yellow fever mosquito
EEB14588     456 NSIQTiNESDYE 467
ETN60597     291 QLVMA-NEPHTI 301
XP_001862905 259 GLVMA-NEPATl 269
EFN86969     251 EAVISpNAPHTP 262
XP_011443070 408 GAILGsSASSST 419
XP_015210807 471 GAVLNgGTPSNR 482 spotted gar
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