Conserved Protein Domain Family
cpdB

?
PRK09420: cpdB 
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase
Links
?
Statistics
?
PSSM-Id: 236506
Aligned: 150 rows
Threshold Bit Score: 997.136
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
114563506   1 MLNKKLLAVVIA--GALGLGGCGsdnddq----tstvaaDIKLRVMETTDLHTNMMDYNYYSGKEDKTIGLVRTASLINA 74 
15888546    1 -MSSLLALHPITrrSLLGGIAASsalvllhpfaaraaanQAHLRIMETTDIHVHVFPYDYYADKPNDTMGLSRTASIIDK 79 
13470608    1 ---MSQLLHPVSrrGFLAGAAATgalivlhpfsaraqanQAHLRIMETTDIHVNVLPYDYYADKANDTMGLSRTASLIDA 77 
222148832   5 AHLRPTDLHPITrrSLLGGFAAAsalvvlhpfaaraaanQAHLRLMETTDIHVNLMPYDYYADKPNDTMGLTRTATLIDE 84 
159044732  10 FLGTAAGASLIAlhPYSARAAAN----------------QAHLRIMETTDLHVHVFPYDYYADRPRDTVGLARTAALIDD 73 
86357396    1 -MSSIFDVGLMSrrSLLGGLAATsalvllhpfsarasanQAHLRLMETTDIHVNVFPYDYYDDKPNDTMGLARTGTIIDN 79 
227822043   1 -MPSTTALHPISrrALLGGLAASsalavlhpfsvraaanQAHLRIMETTDLHVHVFPYDYYADKPNDTLGLARTASIIDA 79 
222085747  16 LQGLSATAALIVlhPFAARAAGN----------------QAHLRLMETTDIHVNVFPYDYYADKPNDTMGLSRTATIIDT 79 
99080877    8 RSFLAGSAGLIAlhPFSVAAASG----------------QVHLRLMETTDLHVHVFPYDYYGDKPVDTLGLARTASLIND 71 
15965379    1 ----MTALHPISrrTLIGGLAATsafvvlhpfstraaanQAHLRIMETTDLHVHVFPYDYYADKPNDTLGLARTASIVDA 76 
114563506  75 ARAEATNSVLVDNGDLLQGSPMGDYIANKfkteNNMLTDTHPVYKAMNTLDYEVGNIGNHEFNYGLSFLEQSLGGANFPY 154
15888546   80 IRAEAGNSMLVDNGDFLQGNPLGDYIAYEr---GMKAGDKHPVINAMNVLGYDCGTLGNHEFNYGLDYMSNTLAGAGFPY 156
13470608   78 VRKEAVNSMLIDNGDLLQGNPMGDYIAYEk---GLKDGDLHPVMKGMNLLGYECSTLGNHEFNYGLSFLDKVLAGANFPF 154
222148832  85 IRAEAGNSMLIDNGDLLQGSPMGDYMAYKk---GIKAGDQHPVMKAMNTLGYDCGTLGNHEFNYGLDFMFNTLAAAKYPI 161
159044732  74 IRAEATNALLVDNGDFLQGNPMGDYIAYEr---GMKEGDTHPVITAMNTVGFDASTLGNHEFNYGLDFLMKSLAGAEFPV 150
86357396   80 IRAEAVNSLLIDNGDVLQGNPMGDYMAYQh---GMKDGDVHPVIKAMNTLGYTVGTLGNHEFNYGLDFMFKVLSGANFPF 156
227822043  80 IRAEATNAILVDNGDFLQGNPMGDYIAYKr---GMKAGDIHPIIAAMNVLGYDCGTLGNHEFNYGLDFMFNVLDGANFPI 156
222085747  80 IRAEATNSLLIDNGDVLQGNPMGDYMAYQh---GMKEGDVHPVIKAMNTLGYEVGTLGNHEFNYGLDFMFKVLGGANFPF 156
99080877   72 IRAEATNSLLVDNGDFLQGNPMGDYIAYEr---GMKEGDQHPVITAMNTVGFDASTLGNHEFNYGISFLMKSLAGAGFPV 148
15965379   77 IRAEAANAVLVDNGDFLQGNPMGDYIAYKr---GMKEGDMHPVIAAMNVLGYDCGTLGNHEFNYGLDFMFNVINGANFPI 153
114563506 155 INANVIcadkdgcwdDVLFSENMFTPYIIKDKVVTDVDGNEHTIKIGYIGFVPPQILQWDRANLDGKVEVLGIVQAANKF 234
15888546  157 VCANLTkgq---lasDPKNDELFFKPYVILEKQIRDGGGVTSPVKVGIIGFVPPQIMMWDSKNLEGKAQTRDIVEAAKAW 233
13470608  155 VCANLIrgte--laaNPRDDKLYLKPYVILDRKIKDGSGAEQPIRIGIIGFVPPQIMVWDLKNLEGNVKTRDIVEAATAW 232
222148832 162 VCANLTkgq---lasDPKNDALFFKPFTIIEKTIKDGAGTESVIKVGFIGFVPPQIMLWDAKNLEGKAQTRDIVEAARAW 238
159044732 151 ISANVVkdm----gaGPRGDTTFIAPYVILDRMLTDGAGETHPIKIGLIGFVPPQIMNWDRKHLEGNVQARDILETARAY 226
86357396  157 VCANLTkgq---lasDPKQDDLFFKPYIIVEKQIKDGSGNESPVKIGFIGFVPPQIMLWDIKNLEGKAQTRDIVEAAKAW 233
227822043 157 VCANLTkga---laaGPRQDQLFLKPYVILDRKVKDGAGQKHPIRIGLIGFVPPQIMTWDAKNLEGKASARDIVKAAEAW 233
222085747 157 VCANLTkgq---lasDPKKDDLFFKPYLILEKKIKDGAGNESPIKIGFIGFVPPQIMLWDIKNLEGKAQTRDIVEAAKAW 233
99080877  149 VCANVAkkt----gaSPREDETLLPPYVILERELTDGAGKAHPIKIGLIGFVPPQVMNWDRKHLEGNVQARDIVECARAY 224
15965379  154 VCANLTkga---maaAPRQDELFLKPYVILDRKVKDGAGQEHPIRIGLIGFVPPQIMTWDAKNLEGKANARDIVKAAEAW 230
114563506 235 VPQMKAEGADIILAIPHSGIgsSENPGDPWAENATYALTNVDGIDAIFFGHSHSVFPSAT-YSDLPNTDVDKGLLNGVPA 313
15888546  234 VPVMKEEGADIIIALSHSGI--DGKGQTERMENASLYLAAVEGIDAIFTGHQHLVFPGPKtWDGIEGADAVKGTLMGKPA 311
13470608  233 VPQMKEEGADIVIALSHSGI---DVKQGDMMENASFFVAGVDGIDAVFTGHQHLVFPGKKdFQSLEGVDTQKGTLQGKPA 309
222148832 239 VPVMKEQGADIVIALSHSGI--DGSGQTERMENASLYLATVDGIDAIFTGHQHLVFPGPKtWDGVQGADPLRGTLMGKPA 316
159044732 227 IPQMREQGADIIIALSHSGI--GSAQETDGMENASVPLAGLDGIDAIATGHSHLVFPSAT-YADYAAVDAEAGTIHGKPA 303
86357396  234 VPAMKEAGADIVIALSHSGI--DGSAPSEKMENASLHLAAVEGIDAIFTGHQHLVFPGPKsWDGIANADPVKGTLHGKPA 311
227822043 234 VPQMREEGAEIVIALSHSGI--GQQAYAENLENASVPLAAINGIDAIVTGHSHLDFPGPK-FEATAGVDNKTGLISGKPG 310
222085747 234 VPVMKEEGADIIIALSHSGI--DGSAPSDKMENASLYVAAVPGIDAVFTGHQHLVFPGPKtWDGIKDADPVKGTLHGKPT 311
99080877  225 VPEMKEKGADIIIALSHSGI--GSADHSDGMENASVPLAAVEGIDAIMTGHSHLVFPSST-YADFAGVDADKGTIHGTPA 301
15965379  231 VPQMREEGADIVIALSHSGI--GQQAYAENLENASVPLAAIEGIDAIVTGHSHLDFPGPK-FDGTPGVDNAKGLISGKPG 307
114563506 314 VMPGRWGDNLGVVDLVVRQVEGKWTVIHeeSTAKARPIYDNANKVALVE---GEASLRDAIEIEHNGTIEYVSQPIGVAA 390
15888546  312 VMAGFWGSHMGLIDLLLEKDGKSWKIVD--FTSEARPIYHRDDSRKVVAdftDKPEVLAAAKTDHEAALAYVRRPVGKTS 389
13470608  310 VMGGFWGSHMGLIDLMLERDGSKWKVVS--ATSEARPIFERVDNKAKPTv-sDDKRIIAALEQDHQATLAYVRRPVGKTS 386
222148832 317 VMAGFWGSHMGLIDFMLEKDGNRWKIVD--FTAEARPIYHRDDAKKIIAdvrDNQDVVAAVKDEHEATLAYVRTPVGKTS 394
159044732 304 TMGGFWGSHMGLIDLMLEREGGAWRVVT--AETEARPISQRNEDRSITAlveSQDYVLASVQEDHDATLAYVRRAVGKTD 381
86357396  312 VMAGFWGSHLGLIDLLLEKDGNSWKIVD--FTSEARPIYHRDDKKKVIAdytDKKEVVEAARTEHEATLAYVRTPVGKTS 389
227822043 311 VMGGFWGSHLGLIDLLVERDGGAWRVVS--STSEARPIYRREEKKVIAEv-gDKAEVLAAAQKDHEATLAYVRTPVGKTS 387
222085747 312 VMAGFWGSHLGLIDLLLEKDGNSWKIVD--FTSEARPIYHRDDKKKVIAdvaDKKEVVEVAKAEHEATLAYVRTPVGKTS 389
99080877  302 VMGGYWGSHMGLIDLMLERDGNGWRVVG--HASEARPISKRNEDRSVTAlveSDQSVLEAVQADHDATLAYVRRAVGKTD 379
15965379  308 VMGGFWGSHLGLIDLLLERDGGQWRVIG--STSEARPIFRREEKKVIAEv-gDKPEVLAAAQKDHEATLAYVRTPVGKTS 384
114563506 391 ANMYSFLTLVQDDPTVQIVSNAQIARVKTLIT-DDLKDLPILSAAAPFKAGGRyaeGDASQYVQVDAGDLSYKNAADLYL 469
15888546  390 APLYSYFALVADDPSVQIVSNAQTWYIKDMLKeGQYKDLPVLSAAAPFKSGGR---GGADYYTDVPAGDIAIKNVADLYL 466
13470608  387 APLYSYFALVADDPSVQVVSQAQTWYLKDILKsTQWKDVPLLSAAAPFKAGGR---NGADYYTDVPAGDIAIKNVADLYL 463
222148832 395 APLYSYFALVADDPSVQIVSNAQTWYIKDMLKeTKYKDYPVLSAAAPFKAGGR---GGADYYTDVPAGDIAIKNVSDLYL 471
159044732 382 APLHSYFALVADDPSVQIVSIAQSWYIADMLKgTEYEGLPILSAAAPFKAGGR---GGPEYYTDVPAGDVAIKNVADLYL 458
86357396  390 APLYSYFALVADDPSVQVVSQAQTWYIKQMLAdTAYKDLPVLSAAAPFKAGGR---GGADYYTDVPAGDIAIKNVADLYL 466
227822043 388 APLYSYFALVADDPSVQIVSQAQTWYIRDMLKdTEHKDLPVLSAAAPFKAGGR---GGADYYTDVAAGDIAIKNVADLYL 464
222085747 390 APLYSYFALVADDPSVQIVSQAQIWYIKDMLKeTQYKDLSVLSAAAPFKCGGR---NGVDYYTDVPAGNIAIKNVADLYL 466
99080877  380 APLHSYFALVADDPSVQIVSIAQTWYISQMLKgTEYEALPILSAAAPFKAGGR---GGPEYYTDVPVGDVAIKNVADLYL 456
15965379  385 APLYSYFALVADDPSVQIVSQAQTWYIREMLKdTEHSDLPVLSAAAPFKAGGR---GGAEYYTDVPAGDIAIKNVADLYL 461
114563506 470 YPNTMVAVKATGAELKDWLECSANQFNQIDPSVSAPQNLINRAGHPTYNFDVIDGLTYKIDVTQPTKFDRSCAVVNADAN 549
15888546  467 YPNTVQAVLINGAQVKNWLEMSAGMFNTVEAGA-KDAPLLNAD-FPSYNFDVIDGVTYQIDISKPAKFDKDGKAVNPDSN 544
13470608  464 YPNTVRAVEITGAQVKEWLEMSAGIFNRIEAGKAD-QALINTD-FPSYNFDVIDGVSYKIDLSQPPKYDAKGGVANAGAN 541
222148832 472 YPNTVQAVLITGAQVKNWLEMSAGMFNQIKPGS-KDAALLNFD-FPSYNYDVIDGVTYEIDLSQPAKYDKDGKAINPDAN 549
159044732 459 YPNTARAVLVTGAQVKDWLERSAGMFNQVTPGA-QDAALLNPD-FPSYNFDVIDGVTYQIDLSQPSKFDAKGELLNPDAN 536
86357396  467 YPNTVQAVAITGAQVKNWLEMSAGMFNHIKAGSKDAPLLNT--DFPSYNFDVIDGVTYQIDLSQPPKYDSSGKAINPDSN 544
227822043 465 YPNTVQAVVIAGEQVRNWLEMSAGIFNQIAPGSTDA-NLINGD-FPSYNFDVIDGVTYQIDLSQPAKYDKDGNLVNATAS 542
222085747 467 YPNTVQAVVINGAQVKNWLEMSAAMFNQVQPGA-KDVALLN-DSFPSYNFDVIDGVTYQIDVSQPRRFSDDGKLLNADAN 544
99080877  457 YPNTVRAVKVTGQQVKDWLERSAGMFNQIEPG--KADQVLLNPSFPSYNFDVIDGVTYQIDLSQPPMFAPKGELINPDSN 534
15965379  462 YPNTVQAVVITGEEVRNWLEMSAGIFNRIAPGSVDA-SLINGD-FPSYNFDVIDGVTYQIVLSQPAKYDKDGNVANPEAS 539
114563506 550 RIVDLAYtapDGTVITgdelAAMSFVVASNNYRAF-GGSFAGTGSDHVVLELPDTNRDALSAYITEQsqpnatggydAMV 628
15888546  545 RIVNLQF---NGKPID----PEQKFVVATNNYRASgGGKFPDIAGDKVIFVAPDTNRDVIVRYIIDQ----------GTI 607
13470608  542 RIVDLMF---GGKPID----PNQKFVVATNNYRAGgGGNFPDINASKIIYEAPDTNRDVIVRYIVSQ----------GTI 604
222148832 550 RIKNLSF---NGKPID----LEQQFVVVTNNYRAGgGGKFPDIASDKVIFVGPDTNRDVIVRYIVAQ----------GTI 612
159044732 537 RIVDLRH---DGAPID----PDARFIIATNNYRASgGGSFPGTGDT-VIFEGPDTNRDVIVRYIVEQ----------GTI 598
86357396  545 RIQNLAF---DGKPID----PAQKFVVVTNNYRAGgGGSFPEIAADKVIFQAPDTNRDVIVRYVHDQ----------GTI 607
227822043 543 RIRDLKF---DGKAID----SAQKFVVATNNYRAGgGGHFPEIAADKVVFVAPDTNRDVIVRYIVEQ----------GTI 605
222085747 545 RIQNLQF---DGKSID----PTQKFVVVSNNYRAGgGGNFPEIAADKVIYKAPDTNRDVIVRYVHEQ----------GTI 607
99080877  535 RIVNLEF---NGAPID----PAQEFIIATNNYRASgGGSFPGAMGDTIVFEGPDTNRDVIVRYIVEQ----------GTI 597
15965379  540 RIRDLKF---DGRPID----PKQRFVVATNNYRAGgGGNFPGIAGDKVVFVAPDTNRDVIVRYIVEQ----------GTI 602
114563506 629 DPSADYNWDFKTIdnatVALDIRFETQDSDVadKFVADNQQRKMVKLPKtADVvaGFAIYSIDL 692
15888546  608 NPSADANWSFAPV----ANTTAIFETGPKGR--HYAAEIKGAKIEDAGD-GAE--GFAKFRLVL 662
13470608  605 NPSADGNWSFGPL----PGTSVVFETGVKAK--DFIADVKSLMIEPAGE-GEA--GFAKYRILL 659
222148832 613 NPSADGNWRFAAI----PDTTASFQTGPKGR--AFATEVKGAKIEDAGD-GAD--GFANYRLIL 667
159044732 599 SPRADGNWRFAPL----PGTTVLFETGPKAI--DYLGEVTSLTIAPAGA-APD--GFMQFRITL 653
86357396  608 NPSADANWTFKPL----PGTTVTFDSGPKAK--QFLAAVKSVKIEDAGD-GAD--GFSKFRLVL 662
227822043 606 NPSADANWKFAPL----KDTSVVFDSSPKAR--QFLAEVKAVTVEDAGD-GAD--GFARFRIRL 660
222085747 608 NPTADGNWTFKPL----PGTTVLFPSSPKAK--DFLAEVKSVKIEDAGE-GTD--GFNNFRLVL 662
99080877  598 SPKADGNWSFAPL----PDTSVLFDTGPKAA--AYAESVPGVTIAPAGD-GPD--GFARFKITL 652
15965379  603 NPSADANWTFAPQ----KDTSVLFDSGPRAR--QFLAEVKAVKIENAGD-GSD--GFARFRIKL 657
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap