Conserved Protein Domain Family
RDD

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pfam06271: RDD 
RDD family
This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).
Statistics
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PSSM-Id: 428859
Aligned: 49 rows
Threshold Bit Score: 63.5079
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q44230                   24 PLATRRLAAWAT-EITLLATTGLVPFGLGVYInsrsdinreplnpalvvteraiarplalpadYGIRNVAWPTNYLWMLA 102  Nos...
Q21KZ2                   13 APLWRRFVALIY-DAFILLAISMIYGAITLGVyvv-------------------------atgITSNDDYQPTVGGPLFQ 66   Sac...
Q02D83                  129 ATTLHRAVAAAL-DWSMVLIGYGIFLTAFHM---------------------------------FGGEFTLTKSNLGIFG 174  Can...
Q7UMX0                  358 ATLGSRTLAAVL-DYLVLAIVLTPISLFLFSSq-----------------------------aSVAQGEPFPGFSAVIAS 407  Pir...
jgilanl:CHU3357          28 ATFWKRVGATLL-DGLILSPVNYGLIFLSMV-----------------------------------------YYKIYVLA 65  
Q5KW61                   25 GGFWLRFWAYCL-DVIVVSSLNRLIVWPLFRL---------------------------------FDWPLAQDGLFAPAA 70   Geo...
USDA:Abu_1180            11 ASMRSRAFAYIIdDLIITIIVMAIFWDRIMS--------------------------------VSHDSEAMIYLMQTELV 58  
jgi:Haur_4654            84 ASWGIRFGAYFL-DVLILLIPSVIINLITGIGvtan------------------------fnlTGSTSSASSLGMYIIGS 138 
PRJNA261003:LJ00_26050   57 TPWFDRVIAFVI-DQLPIAVVTVIGYLVVFGIlag-------------------------asqGSSDGEITTGVGIVAAV 110 
Q6A750                   95 AGWWWRVLSTII-DAVLVWIVVGLTMHETVASivdgyqtfl-------------atsmravnaGASPSDVVTMQSLMKAG 160  Cut...
Q44230                  103 LLAPT---------ALSWWQLYLLAK--TGSTLPKRWFGVKVLN----EEGTPPGLATVVVREGIGRWTvpmsvayilw- 166  Nos...
Q21KZ2                   67 LGWFC---------SLALFYSYFWHK--GGQTAGMKAWKIRVVAq---QENAPLTFKACIIRSL---------------- 116  Sac...
Q02D83                  175 AMFLM---------VGFAYGLLFSLA--GAETPGMHWTQLRLTT----FDGFPPERRQRLVRF----------------- 222  Can...
Q7UMX0                  408 VFGIS---------TQFFYFALSEWR--YGKTLGKRLLGLQVVQ-----AGGRPTLATAAMRSLLFTIPpvlpghigrya 471  Pir...
jgilanl:CHU3357          66 VLSGM---------VHLVYKLYMEKK--YGQTLGKMVVRIKVTG----DAFQPLDYAQTLKRNYYYVLSmifsaiicmnl 130 
Q5KW61                   71 VAAAV---------VFYAYFVLMTKA--FGQTLGKMVFGLKVVD----ERGEPLTWLTVLFREVV--------------- 120  Geo...
USDA:Abu_1180            59 TPLFI---------LKIVYQTFFVWY--YGATIGKIIVKIRVIDa---NHWGRVSMFAALLRAV---------------- 108 
jgi:Haur_4654           139 LLNLI---------INIGYFAYFHGT--TGQTIGKKIVKIRVIR----RTNQPMDFVVAVKRLAITIAStvinlvigmis 203 
PRJNA261003:LJ00_26050  111 LIFVLsl-----apIAYGVWNMGYRQgtTGQSIGKSVMKFKVVSe---QTGQPIGFLMSLVRQV---------------- 166 
Q6A750                  161 FVSDLsnlvgaviiSQAIYQFIMLAA--CAGSVGQLICGLRVVTlnkgKEHRRLVWWRALIRATVWACVe---------- 228  Cut...
Q44230                  167 ------------------rysfafpnlgLFTSLAVLMVIGEALALParr-grKALHDWLAG 208  Nostoc sp. PCC 7120
Q21KZ2                  117 ----------------------------VGPFAFFIAGLGYIWKWFdk--dgHCLHDKLSG 147  Saccharophagus degrada...
Q02D83                  223 ----------------------------FSASLTRCTMLGLLWSLAde--esLAWQDHISR 253  Candidatus Solibacter ...
Q7UMX0                  472 lgdv----------lfnpvtsfgtfavaLLLGWAHYLILAGMFLTArarngnAAIHDLITG 522  Pirellula sp.
jgilanl:CHU3357         131 fsteafqhadtymelmkaqqmqapvykyLQYAFSGVFFIDILFMLNdd--rkKTVHDRWGN 189 
Q5KW61                  121 ----------------------------GKFIAKKLLFIGFLFVAFse--kkKGMHDQFAd 151  Geobacillus kaustophilus
USDA:Abu_1180           109 ----------------------------GRVFSEMFFYIGFLIGFFnd--grKTFHDFTGK 139 
jgi:Haur_4654           204 fnsiddi----aagnlsaatasfgflgiISFVIGIATLLDYLWPLWdg--qkQALHDKIAD 258 
PRJNA261003:LJ00_26050  167 ----------------------------AHIVDGLICYVGYLFPLWda--krQTLADKIMT 197 
Q6A750                  229 ---------------------------iGNQAIVLLTPFSYLMPLWqr--srQTIHDAVAG 260  Cutibacterium acnes
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