3H70


Conserved Protein Domain Family
menC_lowGC/arch

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TIGR01928: menC_lowGC/arch 
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o-succinylbenzoate synthase
This model describes the enzyme o-succinylbenzoic acid synthetase (menC) that is involved in one of the steps of the menaquinone biosynthesis pathway. It takes SHCHC and makes it into 2-succinylbenzoate. Included in this model are low GC gram positive bacteria and archaea. Also included in the seed and in the model are enzymes with the com-name of N-acylamino acid racemase (or the more general term, racemase / racemase family), which refers to the enzyme's industrial application as racemases, and not to its biological function as o-succinylbenzoic acid synthetase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Statistics
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PSSM-Id: 213667
Aligned: 5 rows
Threshold Bit Score: 473.943
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3H70_A        11 YKYSEPFKSQIVTPKVTLTHRDCLFIELIDDkGNAYFGECNAFQTDWYDHETIASVKHVIEQWFEDNRNk-SFETYEAAL 89  Staphylococcus ...
WP_010900678   6 YRVRIPFLRPFTTSFGTENYREALLFRLVHD-GIEAYSEAVTSPIPDYGYEDNATAMHIIGDFAAKYIS--DLPDPSVFM 82  Thermoplasma ac...
WP_010905532   9 FHVQLPMKFNFKTAKGSLNLRDTIIIKVESPdGLSGFGEVVAFTTPFYTSETFADSWKILEETYLPEILqkEFSHPFEIH 88  Lactococcus lactis
ENN11744       9 YKYSEPFKSQIVTPKVTLTHRDCLFIELIDDkGNAYFGECNAFQTDWYDHETIASVKHVIEQWFEDNRNk-SFETYEAAL 87  Staphylococcus ...
O34514        10 YHLSMNLKKPFKNSIETLQERKFLIVEAIDTsGVTGWGEVSAFSSPWYTEETIGTCLHMLKDFFIPNVVgrEFNHPSEVP 89  Bacillus subtil...
3H70_A        90 KLVDSLENTPAARATIVMALYQMFHVLPSFSVAY--G-------ATA---SGLSN-----KQLESLKATKPTRIKLKWTP 152 Staphylococcus ...
WP_010900678  83 ERARGIKGHNMAKAALEMLLWDYHSKVNDQPLYR--YigksrgyANVgisIGMAKieemlEQIEKAVSMGYKRIKIKIAR 160 Thermoplasma ac...
WP_010905532  89 EFFRNPL--PMALAGLENALLDLYFKERNKNLIAglFqekladkIPRgavLGQMSdeqtiKEIDQLINSGVKRIKLKISP 166 Lactococcus lactis
ENN11744      88 KLVDSLENTPAARATIVMALYQMFHVLPSFSVAY--G-------ATA---SGLSN-----KQLESLKATKPTRIKLKWTP 150 Staphylococcus ...
O34514        90 DSLARYKGNRMAKAGLESAVWDIYAKKKGVSLAE--AlggtrdkVPAgvvVGLAPlddmlKEIESYQKEGYQRIKIKIQP 167 Bacillus subtil...
3H70_A       153 QIMhQIRVLRELDFH-FQLVIDANESLDRQDFTQLQLLAREQVLYIEEPFK--DISMLDEVADGTIPPIALDEKATSLLD 229 Staphylococcus ...
WP_010900678 161 GRE-GLVREVRDAFPdIPLSVDANGDYTPSDMPRLKDLDRYDLEYIEQPFPgdDLIYHSRLKKEISTPVCLDESITSADK 239 Thermoplasma ac...
WP_010905532 167 QIGtDLIKKLVKRYPqITFALDANQSFQLTDWPVIKELDELGLACIEEPFDikDLSELKLLTENFLTPICFDESVQDLES 246 Lactococcus lactis
ENN11744     151 QIMhQIRVLRELDFH-FQLVIDANESLDRQDFTQLQLLAREQVLYIEEPFK--DISMLDEVADGTIPPIALDEKATSLLD 227 Staphylococcus ...
O34514       168 GQDvELVKAIRSRFPtIPLMADANSSYELKDISRLKELDDYHLMMIEQPLQadDIVDHRHLQKHLKTAICLDESICSVDD 247 Bacillus subtil...
3H70_A       230 IINLIELYNVKVVVLKPFRLGGIDKVQTAIDTLKSHGAKVVIGGMYEYGLSRYFTAMLARKG--DYPGDVTPAGYYFEQD 307 Staphylococcus ...
WP_010900678 240 ARKAFDIGAADVINIKPGRIGGFTESLKVAEIARENGGHVWVGGMLETGIGRAFNIAFASLDlvDYPGDTSPNEKYFSRD 319 Thermoplasma ac...
WP_010905532 247 LKILTELPFQTMLNVKIGRLGGLYQTQKAIEFCRQHQIGFWIGSMVESGISKILHVQLAALSgnAMAGDLSDSKHYFDLD 326 Lactococcus lactis
ENN11744     228 IINLIELYNVKVVVLKPFRLGGIDKVQTAIDTLKSHGAKVVIGGMYEYGLSRYFTAMLARKG--DYPGDVTPAGYYFEQD 305 Staphylococcus ...
O34514       248 ARRAIELGSCKIINIKPSRVGGLTEALKIHDLCKEHHMQVWCGGMLETGISRAQNVALASLPqfTIPGDISSSSRYWDED 327 Bacillus subtil...
3H70_A       308 VVAHSGI 314 Staphylococcus aureus
WP_010900678 320 IVKNPFR 326 Thermoplasma acidophilum
WP_010905532 327 LVQPEIA 333 Lactococcus lactis
ENN11744     306 VVAHSGI 312 Staphylococcus aureus M1462
O34514       328 IVTPDIR 334 Bacillus subtilis subsp. subtilis str. 168
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