2FCP,1XKW,1KMO,4EPA,1FEP,4AIP


Conserved Protein Domain Family
TonB-siderophor
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TIGR01783: TonB-siderophor 
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TonB-dependent siderophore receptor
This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Links
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Statistics
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PSSM-Id: 273805
Aligned: 24 rows
Threshold Bit Score: 410.65
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2FCP_A    45 KVPQSi------sVVTAEEMALHQPk--SVKEALSYtPGVSVGTRGASNTYD---H---LIIRGFAAe-gQS-----QNN 104 Escherichia coli K-12
P46359    48 NVSST--------VVSAPELSDAGV---TASDKLPRvLPGLNIENSGNMLFS---T---ISLRGVSSaqdFYnp--aVTL 108 Yersinia pestis
P13036   132 EHAGAr------dVIRREDFAKTGAt--TMREVLNRiPGVSAPENNGTGSHD---LamnFGIRGLNPrlaSR-----STV 195 Escherichia coli K-12
AAL35618  43 SSSES---------LTTDDLSLKQAd--HMSDLLRDiPGVDVGGTHSVNQR--------INIRGLGEt--N------LDI 95  Vibrio cholerae
AAK71635  45 EIAQTt------wVIENAELEQQIQggkELKDALAQlIPGLDVSSQSRTNYG-------MNMRGRPLv-vLI-----DGV 105 Shigella boydii
P14542    46 EMAQTt------wVIENAELEQQIQggkELKDALAQlIPGLDVSSRSRTNYG-------MNVRGRPLv-vLV-----DGV 106 Escherichia coli
CAA66129 157 DIERSgppdaaidVLERTELEELKTgsdSLATVLSKvIPGMADSSHTVTDFG-------QTLRGRGMl-vLL-----DGI 223 Cupriavidus metalli...
P05825    47 APGVS--------TITADEIRKNPVa-rDVSKIIRTmPGVNLTGNSTSGQRG---NnrqIDIRGMGPentLIlidgkPVS 114 Escherichia coli K-12
1KMO_A   132 EHAGAr------dVIRREDFAKTGAt--TMREVLNRiPGVSAPENNGTGSHDlamN---FGIRGLNPrlaSR-----STV 195 Escherichia coli K-12
4EPA_A    28 annvSs------tVVSAPELSDAGV---TASDKLPRvLPGLNIENSGNXLFS---T---ISLRGVSSa-qDFyn-paVTL 90  Yersinia pestis

2FCP_A   105 YLNGLKLQG------Nfy-----nDAVIDPYMLERAEIMRGPVSVLYGKSSPGGLLNMVSKRPTT------EP---LKEV 164 Escherichia coli K-12
P46359   109 YVDGVPQLS------Tn--------TIQALTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDS------TP---RGYI 165 Yersinia pestis
P13036   196 LMDGIPVPF------ApygqpqlsLAPVSLGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQdf---gIE---AGVE 263 Escherichia coli K-12
AAL35618  96 RLDGASQHA------Nmfh--higNLTLNPDILKSADVQVGNNSVTQSGLG--GSVYFETKNAKD------LL---VGGE 156 Vibrio cholerae
AAK71635 106 RLNSSRSDS------Rq-------LDSVDPFNIDHIEVISGATALYGGGSTG-GLINIVTKKG--------QP---ETMM 160 Shigella boydii
P14542   107 RLNSSRTDS------Rq-------LDSIDPFNMHHIEVIFGATSLYGGGSTG-GLINIVTKKG--------QP---ETMM 161 Escherichia coli
CAA66129 224 PLNTNRDSA------Rn-------LANIDPALVERVEVLRGSSAIYGGGPTG-GIVSITTRPAGG------EP---KADT 280 Cupriavidus metalli...
P05825   115 SRNSVRQGW------RgerdtrgdTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGewhgswDA---YFNA 185 Escherichia coli K-12
1KMO_A   196 LMDGIPVPFapygqpQl------sLAPVSLGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQ------DFgieAGVE 263 Escherichia coli K-12
4EPA_A    91 YVDGVPQLS------T--------NTIQALTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDS------TP---RGYI 147 Yersinia pestis

2FCP_A   165 QFKAGTDSLFQTGFDFSDSLD-----DDGVYSYRLTGLARSANAQQKGSEEQR-Y-AIAPAFTWRp-------------- 223 Escherichia coli K-12
P46359   166 EGGVSSRDSYRSKFNLSGPIQ------DGLLYGSVTLLRQVDDGDMINPATGSdD-LGGTRASIG--------------- 223 Yersinia pestis
P13036   264 GQLSPTSSQNNPKETHNLMVGg---tADNGFGTALLYSGTRGSDWREHSATRIdD-LMLKSKYAPd-------------- 325 Escherichia coli K-12
AAL35618 157 QFGARIFGGYASNDNQQGSLTvy-gqLSETVDAMVYGQGISRDNFEDGAGKETfG-VKGDTYNVLakv----------gf 224 Vibrio cholerae
AAK71635 161 EFEAGTKSGFNGSKDHDERIAgavsgGNDHISGRLSVAYQKFGGWFDGNGDAT-L-LDNTQTGLQhsnrldimgtgtlni 238 Shigella boydii
P14542   162 EFEAGTKSGFSSSKDHDERIAgavsgGNEHISGRLSVAYQKFGGWFDGNGDAT-L-LDNTQTGLQysdrldimgtgtlni 239 Escherichia coli
CAA66129 281 TVTMSTPLSRLRRGRLERQRAaalfgQQRDARLCVRPRRAPYRQSYDAKGHALrR-SQARATCSTrttttsaassasfap 359 Cupriavidus metalli...
P05825   186 PEHKEEGATKRTNFSLTGPLG-----DEFSFRLYGNLDKTQADAWDINQGHQSaR-AGTYATTLPag------------r 247 Escherichia coli K-12
1KMO_A   264 GQLSPTSSQNNPKETHNLMVGg---tADNGFGTALLYSGTRGSDWREHSATRI-D-DLMLKSKYAp-------------d 325 Escherichia coli K-12
4EPA_A   148 EGGVSSRDSYRSKFNLSGPI------QDGLLYGSVTLLRQVDDGDXINPATGS-DdLGGTRASI---------------- 204 Yersinia pestis

2FCP_A   224 DDKTNFTFLSYFQNEPETGYYg-----wLPKEGTveplpngKRLPTDFNEG--AKNnTYSRNEKMVGYSFDHEFNDTFTV 296 Escherichia coli K-12
P46359   224 N--VKLRLAPDDQPWEMG----------FAASREc------tRATQDAYVG----WnDIKGRKLSISDGSPDPYMRRCTD 281 Yersinia pestis
P13036   326 EVHTFNSLLQYYDGEADMPG---------GLSR--------ADYDADRWQS---TRpYDRFWGRRKLASLGYQFQPDSQH 385 Escherichia coli K-12
AAL35618 225 EPAVGHRFQVSYDVYRDQGDy-------SPR-P---------DMAGSANLGlsKNRlVPTHYDRDTITGSYELKQDKHRG 287 Vibrio cholerae
AAK71635 239 DESRQLQLITQYYKSQGDDNYglnlgkgFSAISGsstpyvsKGLNSDRIPGt-ERH-LISLQYSDSDFLGQELVGQVYYR 316 Shigella boydii
P14542   240 DESRQLQLITQYYKSQGDDDYglnlgkgFSAIRGtstpfvsNGLNSDRIPGt-DGH-LISLQYSDSAFLGQELVGQVYYR 317 Escherichia coli
CAA66129 360 DQRIQLASSAILTPSRTRAGRri---raWPNCRRaacprraLDGLQLADQNqiRNT-LVNLEYEHRDLLGSQLSAQFYYR 435 Cupriavidus metalli...
P05825   248 EGVINKDINGVVRWDFAPLQS-------LELEAG-------YSRQGNLYAGdtQNTnSDSYTRSKYGDETNRLYRQNYAL 313 Escherichia coli K-12
1KMO_A   326 EVHTFNSLLQYYDGEADMP-------------GGls----rADYDADRWQSt---RpYDRFWGRRKLASLGYQFQPDSQH 385 Escherichia coli K-12
4EPA_A   205 -GNVKLRLAPDDQPWEx----------gFAASREc------tRATQDAYVG----WnDIKGRKLSISDGSPDPYXRRCTD 263 Yersinia pestis

2FCP_A   297 RQNLRFAENKTSQnSVYGYGVCSDpanayskqcaalapadkGHYLARKYVVDDEK--LQNFSVDTQLQSKFATGDIDHTL 374 Escherichia coli K-12
P46359   282 SQTLSGKYTTDDWvFNLISAWQQQh---------------ySRTFPSGSLIVNMP--QRWNQDVQELRAATLGDARTVDM 344 Yersinia pestis
P13036   386 KFNIQGFYTQTLR-----SGYLEQ-----------------GKRITLSPRNYWVR----G--IEPRYSQIFMIGPSAHEV 437 Escherichia coli K-12
AAL35618 288 KVTLYSSQTEIDRdESVMAGVWPG-----------------NRLSRNTATNRNVG-------INALFQSDYELAAHRNQV 343 Vibrio cholerae
AAK71635 317 DESLRYYPFPTVNaNKQATAFSSSqq--------------dTDQYGMKLTLNSQL--MDGWQITWGLDAEHERFTSNQMF 380 Shigella boydii
P14542   318 DESLRFYPFPTVNaNKQVTAFSSSqq--------------dTDQYGMKLTLNSKP--MDGWQITWGLDADHERFTSNQMF 381 Escherichia coli
CAA66129 436 NYYSRFTPFDARAvPVRGGNVDQAmq--------------dSEVFGSRLTVKTPLgrDKRTRVIWGMDFEQETSDMPIDI 501 Cupriavidus metalli...
P05825   314 TWNGGWDNGVTTSnWVQYEHTRNSri--------------pEGLAGGTEGKFNEKatQDFVDIDLDDVMLHSEVNLPIDF 379 Escherichia coli K-12
1KMO_A   386 KFNIQGFYTQTLR-----SGYLEQ-----------------GKRITLSPRNYWVR------GIEPRYSQIFMIGPSAHEV 437 Escherichia coli K-12
4EPA_A   264 SQTLSGKYTTDDWvFNLISAWQQQh---------------ySRTFPSGSLIVNXP--QRWNQDVQELRAATLGDARTVDX 326 Yersinia pestis

2FCP_A   375 LTGv-----DFMRMRNDINA-WFG-YDDSVPLLNLYNPShhhhhhgsvNTDFDFNAKDPANSGPYRILNkqk-qtGVYVQ 446 Escherichia coli K-12
P46359   345 VFGl-----YRQNTREKLNSaYDM-PTMPYLSSTGYTTA---------ETLAAYSDLTWHLTDRFDIG--------GG-- 399 Yersinia pestis
P13036   438 GVG------------YRYLN---E-STHEMRYYTATSSG---------QLPSGSSPYDRDTRSGTEAH-------AWYLD 485 Escherichia coli K-12
AAL35618 344 SYG--------------------------MDYVDQTSKA---------TYGSTPFMEESAVSTAVFAEN----------- 377 Vibrio cholerae
AAK71635 381 FDLaqasasGGLNNHKIYTT-GRY-PSYDITXLAAFLQS---------SYDINDIFTVSGGVRYQYTENrvddfiDYTQQ 449 Shigella boydii
P14542   382 FDLaqasasGGLNNKKIYTT-GRY-PSYDITNLAAFLQS---------GYDINNLFTLNGGVRYQYTENkiddfiGYAQQ 450 Escherichia coli
CAA66129 502 FDLkay-daSGGRIFNKIGTlTYM-PPITTRSIGALPSC---------RHKFNEQWSTEGGLRYQYARa------SFSDF 564 Cupriavidus metalli...
P05825   380 LVNq-----TLTLGTEWNQQrMKD-LSSNTQALTGTNTG---------GAIDGVSTTDRSPYSKAEIFS------LFAEN 438 Escherichia coli K-12
1KMO_A   438 GVGy----rYLN-----------E-STHEMRYYTATSSG---------QLPSGSSPYDRDTRSGTEAH-------AWYLD 485 Escherichia coli K-12
4EPA_A   327 VFGl-----YRQNTREKLNS-AYDxPTXPYLSSTGYTTA---------ETLAAYSDLTWHLTDRFDIGG------GV--- 382 Yersinia pestis

2FCP_A   447 DQAQWDKVLVTLGGRYDWADQES---LNRVAGTTDKRDDKQFTWRGGVNYLFDNGVTPYFSYSESFEPSSQ--------- 514 Escherichia coli K-12
P46359   400 VRFSHDKSSTQYHGSMLGNPFGD----------QGKSNDDQVLGQLSAGYMLTDDWRVYTRVAQGYKPSGYniv----pt 465 Yersinia pestis
P13036   486 DKIDIGNWTITPGMRFEHIESYQn---NAITGTHEEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYsq-----ig 557 Escherichia coli K-12
AAL35618 378 KLYVNDVWSLTAGLRFDDFKRKA---------MTGTKDFDEVTWSLGTEWDVTSDWTLFANARSLFKGPELletfvryqd 448 Vibrio cholerae
AAK71635 450 QKIAAGKAISADAIPGGSVDYDNflfNAGLLMHITERQQAWFNFSQGVALPDPGKYYGRGIYGAAVNGHLSlt-----ks 524 Shigella boydii
P14542   451 RQIGAGKATSADAFWRLSR-LRHflfNAGLLMHITEPQQAWLNFSQGLELPDPGKYYGRGIYGAAVNGHLPlt-----ks 524 Escherichia coli
CAA66129 565 VPLSQSRVTNPATVSGGAVDYSAvlgNIGVAYKPVKDHEFYAAFSQGFNLPDIGLQVGNARAGFDIGS------------ 632 Cupriavidus metalli...
P05825   439 NMELTDSTIVTPGLRFDHHSIVGnnwSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCyasa--ggc 516 Escherichia coli K-12
1KMO_A   486 DKIDIGNWTITPGMRFEHIESYQ---NNAITGTHEEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYsq-----ig 557 Escherichia coli K-12
4EPA_A   383 -RFSHDKSSTQYHGSXLGNP----------FGDQGKSNDDQVLGQLSAGYXLTDDWRVYTRVAQGYKPSGYniv----pt 447 Yersinia pestis

2FCP_A   515 VGKDGNIFAPSKGKQYEVGVKYVP--EDrpIVVTGAVYNLTKTnNLMA-DPEGSFFSVEgGEIRARGVEIEAKAAL---- 587 Escherichia coli K-12
P46359   466 AGLDAKPFVAEKSINYELGTRYET--ADv-TLQAATFYTHTKDmQLYS-GPVRMQTLSNaGKADATGVELEAKWRF---- 537 Yersinia pestis
P13036   558 KAVQSGNVEPEKARTWELGTRYDD--GA--LTAEMGLFLINFNnQYDS-NQTNDTVTAR-GKTRHTGLETQARYDLgtlt 631 Escherichia coli K-12
AAL35618 449 QARLADNIKPETGLYTQGGVRFDKtyGDhfVGANFTLFKTQIDdHIRT---SNSYLISNvGDMEIKGFELSTTYAY---- 521 Vibrio cholerae
AAK71635 525 VNVSDSKLEGVKVDSYELGWRFTG--DNl-RTQIAAYYSLSNK--SVE-RNKDLTISVKdDRRRIYGVEG-AVDYL---- 593 Shigella boydii
P14542   525 VNVSDSKLEGVKVDSYELGWRFTG--NNl-RTQIAAYYSISDK--SVV-ANKDLTISVVdDKRRIYGVEG-AVDYL---- 593 Escherichia coli
CAA66129 633 -----SDLQPVKTNNYELGWRGAF--GN--TLGSLAIFYTTSDlGDVQ-SFNNGLILTR-TAEKIYGVEA-SADYL---- 696 Cupriavidus metalli...
P05825   517 YLQGNDDLKAETSINKEIGLEFKR--DG--WLAGVTWFRNDYRnKIEAgYVAVGQNAVGtDLYQWDNVPKAVVEGLe--- 589 Escherichia coli K-12
1KMO_A   558 KAVQSGNVEPEKARTWELGTRYDD--GA--LTAEMGLFLINFNnQYDS-NQTNDTVTAR-GKTRHTGLETQARYDLgtlt 631 Escherichia coli K-12
4EPA_A   448 AGLDAKPFVAEKSINYELGTRYET--ADv-TLQAATFYTHTKDxQLYS-GPVRXQTLSNaGKADATGVELEAKWRF---- 519 Yersinia pestis

2FCP_A   588 --SASVNVVGSYTYTDAEYTTDT--T-YKGNTPAQVPKHMASLWADYTFFDGPlsGL-TLGTGGRYTGSSY------GDP 655 Escherichia coli K-12
P46359   538 --APGWSWDINGNVIRSEFTNDSe--lYHGNRVPFVPRYGAGSSVNGVIDTRYg-AL-MPRLAVNLVGPHY------FDG 605 Yersinia pestis
P13036   632 ptLDNVSIYASYAYVNAEIREKGd---TYGNLVPFSPKHKGTLGVDYKPGNWTfnLN-SDFQSSQFADNANtv--keSAD 705 Escherichia coli K-12
AAL35618 522 -----QAASAKLSYAHSDANDVTngG-PMLNSVGNSADMGDSIALSLGYQADSidTL-FGWTSIVVLDEDN------VVA 588 Vibrio cholerae
AAK71635 594 --IPDTDWSTGVNFNVLKTESKVngQ-WQKYDVKESSPSKATAYINWAPEPWS---L-R----VQSTTSFD------VSD 656 Shigella boydii
P14542   594 --IPDTDWSTGVNFNVLKTESKVngT-WQKYDVKTASPSKATAYIGWAPDPWS---L-R----VQSTTSFD------VSD 656 Escherichia coli
CAA66129 697 --STDERWGAGGTFTWMQGRETPqgRdSQQMTGYRIPPLKLTGYVQYRPVPQWnnRL-QATFFAGYDYRLNg-----VTS 768 Cupriavidus metalli...
P05825   590 -gSLNVPVSETVMWTNNITYMLKseNkTTGDRLSIIPEYTLNSTLSWQAREDLsmQT-TFTWYGKQQPKKYnykgqpAVG 667 Escherichia coli K-12
1KMO_A   632 ptLDNVSIYASYAYVNAEIREKg--D-TYGNLVPFSPKHKGTLGVDYKPGNWTf-NLnSDFQSSQFADNANtv--keSAD 705 Escherichia coli K-12
4EPA_A   520 --APGWSWDINGNVIRSEFTNDSe-L-YHGNRVPFVPRYGAGSSVNGVIDTRYg-AL-XPRLAVNLVGPHY------FDG 587 Yersinia pestis

2FCP_A   656 ANSFKVGSYTVVDALVRYDLArvgmAGSNVALHVNNLFDREYVASCF---N------------TYGCFWGAERQVVATAT 720 Escherichia coli K-12
P46359   606 DNQLRQGTYATLDSSLGWQAT----ERMNISVYVDNLFDRRYRTYGYmngS------------SAVAQVNMGRTVGINTR 669 Yersinia pestis
P13036   706 GSTGRIPGFMLWGARVAYDFGpq-mADLNLAFGVKNIFDQDYFIRSYd-dN------------NKGIYAGQPRTLYMQGS 771 Escherichia coli K-12
AAL35618 589 G-AAKKEGYDVHNLYAQWTPYs--vPNLVLTFGVDNVFDELYVSHASrvgLak---------sFVADDYEPGRSYKLSAA 656 Vibrio cholerae
AAK71635 657 AEGNDINGYTTVDFISSWQLP-----VGTLSFSVENLFDRDYTTVWGqraPlyysp--gygpaSLYDYKGRGRTFGLNYS 729 Shigella boydii
P14542   657 AQGYKVDGYTTVDLLGSYQLP-----VGTLSFSIENLFDRDYTTVWGqraPlyysp--gygpaSLYDYKGRGRTFGLNYS 729 Escherichia coli
CAA66129 769 FGRRDVSSYTTLDLISSYQVTk----KDTVTVGIQNLLNRYYYPLYSqllRn-------------sNNTSHLRRPASRSP 831 Cupriavidus metalli...
P05825   668 PETKEISPYSIVGLSATWDVT----KNVSLTGGVDNLFDKRLWRAGNaqtTgdlaganyiagaGAYTYNEPGRTWYMSVN 743 Escherichia coli K-12
1KMO_A   706 GSTGRIPGFMLWGARVAYDFGpq-mADLNLAFGVKNIFDQDYFIRSYd-dN------------NKGIYAGQPRTLYMQGS 771 Escherichia coli K-12
4EPA_A   588 DNQLRQGTYATLDSSLGWQAT----ERXNISVYVDNLFDRRYRTYGYxngS------------SAVAQVNXGRTVGINTR 651 Yersinia pestis

2FCP_A   721 FRF 723 Escherichia coli K-12
P46359   670 IDF 672 Yersinia pestis
P13036   772 LKF 774 Escherichia coli K-12
AAL35618 657 YQF 659 Vibrio cholerae
AAK71635 730 VLF 732 Shigella boydii
P14542   730 VLF 732 Escherichia coli
CAA66129 832 PPT 834 Cupriavidus metallidurans CH34
P05825   744 THF 746 Escherichia coli K-12
1KMO_A   772 LKF 774 Escherichia coli K-12
4EPA_A   652 IDF 654 Yersinia pestis
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