4WJT,4WLK,4WLI


Conserved Protein Domain Family
DPBB_YuiC-like

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cd22786: DPBB_YuiC-like 
Click on image for an interactive view with Cn3D
double-psi beta-barrel fold of YuiC subfamily proteins
The YuiC subfamily includes a group of conserved double-psi beta-barrel (DPBB) fold proteins, such as Bacillus subtilis protein YuiC, cell wall shaping protein YabE, cell wall-binding protein YocH, as well as Clostridium tetani phosphatase-associated protein PapQ. YuiC is a Firmicute stationary phase survival (Sps) protein that closely resembles the Barwin-like endoglucanase beta barrel of MltA. It is a double-psi beta-barrel (DPBB) fold that consists of two interlocked "psi-structure" motifs related by a pseudo-2-fold axis and may be involved in substrate binding and catalysis.
Statistics
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PSSM-Id: 439263
Aligned: 44 rows
Threshold Bit Score: 61.4644
Created: 4-May-2019
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
 
homodimerchemical
Conserved site includes 45 residues -Click on image for an interactive view with Cn3D
Feature 1:homodimer interface [polypeptide binding site]
Evidence:
  • Structure:4WJT; Bacillus subtilis protein YuiC forms a swapped homodimer, contacts at 4A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1         ########## #                                                                    
4WJT_A         32 YPVQRVTATGYTagaestgk------------------------------------------------------------ 51   Bacillus subt...
BAG09226     2152 VTKVKVTATGIYptk----------------------------------------------------------------- 2166 Finegoldia ma...
PKP23653      162 YKAVTVTATSYSpcnsg--------------------------------------------------------------- 178  Bacteroidetes...
XP_003063898    5 PYTRTMEATAYSsdwrscgwtwglslgplpfyvplclgtrpsgtrewplvprprrdvadakadlalgglalacltalsva 84   Micromonas pu...
RLT52396      305 IRPREMTVTAYCl------------------------------------------------------------------- 317  Chloroflexi b...
XP_024533541    3 PSKKLIECTAYCscgyccnwewgiklpgfyylgispswvplrf------------------------------------- 45   Selaginella m...
XP_024386503    3 PYTLEIECTAYCrcgyccnwewglrlpsafpfylgfspslmpvr------------------------------------ 46   Physcomitrell...
ABK24377        3 PFQREIECTAYCscgyccnwewglmlpgpfylgfspswlpvhl------------------------------------- 45   Sitka spruce
TAH57125       35 PQTMLMEITAYCyt------------------------------------------------------------------ 48   Sphaerochaeta...
TFH13512       31 DVVRTLEVTGYCrcgkccswhrtwygk----------------------------------------------------- 57   Lentisphaeral...
Feature 1                                                                   # ## #                
4WJT_A         52 -----------------------------------------------npgdplyGLTYSGVKVKrd-------------- 70   Bacillus subt...
BAG09226     2167 ----------------------------------------------------enPNTPNGTPIK---------------- 2178 Finegoldia ma...
PKP23653      179 -------------------------------------------------tgtcyPKTALGTTVK---------------- 193  Bacteroidetes...
XP_003063898   85 sgalldgsflrrraaiaargrvaraaalgagvgatafpigrywaetdlaglpysGATASGKQPRamrppitrvnpltdp- 163  Micromonas pu...
RLT52396      318 -----------------------------------------------------rSNTSSGAPPT---------------- 328  Chloroflexi b...
XP_024533541   46 -----------------------rkrkrgyldeaalpliakfwtatslsgspyyGLTSNGTFPAqarppifsklsflqyh 102  Selaginella m...
XP_024386503   47 ----------------------lrtrkkgnrehqrlpffckfwtattqngqpyyGLTSNGSFPAqarpplfsklslmnyq 104  Physcomitrell...
ABK24377       46 ------------------------rhrkkgyienklpllarywtattltgspyyGLTSAGTVPAqarppilsklsllqyk 101  Sitka spruce
TAH57125       49 -----------------------------------------------------gNRTASGTWPK---------------- 59   Sphaerochaeta...
TFH13512       58 ---------------------------------------pvyssgpmkgkrkliGITASGKRAS---------------- 82   Lentisphaeral...
Feature 1                         # #       ###  ####### ##  #                  # #              #
4WJT_A         71 ---------------lYSTVAADPSvFPI--GTILFIPNYGLGVVADTGSAi-kGNRLDLYFETVkd----------vyN 122  Bacillus subt...
BAG09226     2179 ----------------KGIILADGSiIAK--GAKVEIPGYGNATVDGSTNDt-rGYNIKIAFNTKee-----------aI 2228 Finegoldia ma...
PKP23653      194 ----------------KGVLAVDLTwWPIlkNTKICVPGYGIGIVQDTGSYpgtHHWIDLGYTDAefaaagqktffnltS 257  Bacteroidetes...
XP_003063898  164 -iafasrvltlqwgpvDGSIAADTSvYPF--GTRMKIEGMGWGVVEDRGGGvvgGDRIDIYVRRRkr-----------aL 229  Micromonas pu...
RLT52396      329 ----------------PGTAAAGPM-VPI--GSRFSVPGYGEVVVRDRNANy-gPNQLDVWLADCnq-----------aI 377  Chloroflexi b...
XP_024533541  103 klparlllfpwrlfprHGTIAADTNyYPF--GTRMFVPGYGWGKVEDRGGAikgPARIDLYHQSHne-----------aI 169  Selaginella m...
XP_024386503  105 nlparllffpwkllprHGTIAADTNyYPF--GTRMFIPGYGWGEVEDRGGAikgPHRIDLYHRSHkt-----------aL 171  Physcomitrell...
ABK24377      102 -klpgrlllpwrifprQGTIAADTDfYPF--GTRMFIPGYGWGEVEDRGTAikgPRKIDLYHCSHte-----------aL 167  Sitka spruce
TAH57125       60 ----------------VGTVAADTKvLPF--GTKVYIPGYGIGTVEDRGGAi-kGNMLDVYLPSRsa-----------aI 109  Sphaerochaeta...
TFH13512       83 ----------------RGTIAADTSrYPF--GTVVNVPGYGFGRVEDRGGAi-kGDRIDLFFGSHrd-----------aE 132  Lentisphaeral...
Feature 1          ############
4WJT_A        123 EWGKKTLDVYVIK 135  Bacillus subtilis subsp. subtilis str. 168
BAG09226     2229 AFGKKSLEINVHT 2241 Finegoldia magna ATCC 29328
PKP23653      258 RFGKVNVNRNRMF 270  Bacteroidetes bacterium HGW-Bacteroidetes-22
XP_003063898  230 EFGRKRVEVTVHP 242  Micromonas pusilla CCMP1545
RLT52396      378 RWGRRTLEVTPEQ 390  Chloroflexi bacterium
XP_024533541  170 HWGRRKLQVLVVL 182  Selaginella moellendorffii
XP_024386503  172 QWGRRKVQVLVIK 184  Physcomitrella patens
ABK24377      168 KWGRRKLQVLVVL 180  Sitka spruce
TAH57125      110 EWGRKKNVEVTIV 122  Sphaerochaeta sp.
TFH13512      133 RWGRRRLKTQIWL 145  Lentisphaerales bacterium

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