Conserved Protein Domain Family
prpD

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PRK09425: prpD 
bifunctional 2-methylcitrate dehydratase/aconitate hydratase
Links
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Statistics
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PSSM-Id: 181845
Aligned: 175 rows
Threshold Bit Score: 727.825
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
93006130    1 MSTVESNVRPEYDSEIEKIADYVLNYSIDndspnSADAWNTARYCLMDTLGCGLLALRFPECTKHLGPDCADQITPNGAR 80 
305675061   1 --------MLKTDHVIEEITDYVLEKEIT-----SSEAYTTAGHVLLDTLGCGILALRYPECTKLLGPIVPETIVPNGSK 67 
56963571    1 --MDLKTDTRKTDLLLEEIAEYVLKKEIT-----SEEALETAAHVLVDTIGCGILALRYPECVKMLGPVVPGTIVPNGVK 73 
154686672   1 -----MTEPRRMDAVIEEISDYVLHQEID-----SSEAFTTAGHVLLDTIGCGILALSYPECTKLLGPIVPGTAVPNGSR 70 
52082382    1 -MKTESQTLQNCDQLLEEIADYTVNAKIS-----SEEAIETARYVLMDTLGCGILALKYPECAKHLGPIAPGTVVPNGTR 74 
52787772    1 -MKTESQTLQNCDQLLEEIADYTVNAKIS-----SEEAIETARYVLMDTLGCGILALKYPECAKHLGPIAPGTVVPNGTR 74 
157692616   1 --MNKTAVANQTDQLLEEIAAYAVDGEIT-----SKEAIETARYVLIDTLGCGMLALNFPECTKHLGPIVPGTVVPNGAR 73 
258510797   2 SSTVDRQGGRPFDDVIVQMTDYVMKPEVA-----SDEALHIARHVLMDTIGVGLLALSFPECAKHIGPYVPGAVMPGGVR 76 
108805205   1 ----------MADRVIERISEYVCTYEPQ-----SPLARETARYCLMDSIGCALLALRYPECAKLLGPAVPGTVVPHGSR 65 
297621694   1 ---MDPLVKPLADEVIAKIANYTINYNPD-----SSEAFRTASLCLADSIGCAILSLRFPACTKLLGPVIPETVVPKGVP 72 
93006130   81 VPGTSYRLDPIKAAFDIGCIVRWLDYNDTWLAAEWGHPSDNLGAILAVADYISQQNVSQGHAPLIMKDVLEAMIMAHEIQ 160
305675061  68 VPGTSYVLDPVRAAFNIGCMIRWLDYNDTWLAAEWGHPSDNLGGILATADYVSRVGLSEGKDPLTVRDVLEMMIKAHEIQ 147
56963571   74 VPGTSHVLDPVRGAFNIGTMIRWLDYNDTWLAAEWGHPSDNLGGILATADYISRKNIAEGKAPLTIHDVLIAMVKAHEIQ 153
154686672  71 VPGTPFVLDPVTAAFNIGCINRWLDYNDTWLAAEWGHPSDNLGGILACADYISRVRISEGKEPLTVRDVLCAMIKAHEIQ 150
52082382   75 VPGTQFELDPVHGAFNIGCMIRWLDYNDTWLAAEWGHPSDNLGAILACADYVSRQLLAAGKEPLTINDVLTAIVKAHEIQ 154
52787772   75 VPGTQFELDPVHGAFNIGCMIRWLDYNDTWLAAEWGHPSDNLGAILACADYVSRQLLAAGKEPLTINDVLTAIVKAHEIQ 154
157692616  74 VPGTSFVLDPVQAAFDIGCMIRWLDYNDTWLAAEWGHPSDNLGGILAVSDYISRTRLANGEEPLSMNDVLHAIVKAHEIQ 153
258510797  77 VPGTKYELDPVQTAFNIGVMIRWLDYNDTWLAMEWGHPSDNLGGILAVADYVSREARRRGQKPLTVRQLLERMVQAHEIQ 156
108805205  66 VPGTPYELDPVKAAFDIGSAIRWLDYNDTWLAAEWGHPSDNLGAILAVSDHLSRSRRARGEEPLYVRDVLSAAIEAHEIQ 145
297621694  73 IPGTDYVLDPISAAFDIGTMIRWLDYNDTWLALEWGHPSDNLGGILAVADYLDRNG-----ERLTVRDVLAAMIQAHEIQ 147
93006130  161 GVLALDNSFNRVGLDHVFLVKLASTAVVAKLYKLPHERIMAAISQAIVDGQALRTYRHAPNAGSRKSWAAGDATSRAVRL 240
305675061 148 GVLALENSLNRVGLDHVLFVKVATTAVAAKLLGGGRVEIKNALSNAWIDNAALRTYRHSPNTGSRKSWAAGDATSRGVHL 227
56963571  154 GVLALENSFNRVGLDHVLLVKVATTAVVAGMLGGTKEEVVNAVSHAWIDNSSLRTYRHAPNTGSRKSWAAGDATSRGVFL 233
154686672 151 GILALENSLNRVGLDHVLFVKVATAAVCAQMLGGSKEEINNAVSHAWIDNSSLRTYRHAPNTGSRKSWAAGDATSRGVYL 230
52082382  155 GVLALDNSLNRNGLDHVLFVKVASTAVACSLLGGTKQDVINAVSQAWVDNSSLRTYRHAPNTGSRKSWAAGDATSRGVRL 234
52787772  155 GVLALDNSLNRNGLDHVLFVKVASTAVACSLLGGTKQDVINAVSQAWVDNSSLRTYRHAPNTGSRKSWAAGDATSRGVRL 234
157692616 154 GVLALENCLNRNGLDHVLFVKVATSAVVCALLGGTKEDVQHVLSQAFVDNSPLRTYRHAPNTGSRKSWAAGDATSRGVRL 233
258510797 157 GVLALENSLNRRGLDHVLFVKVASTAVTTAMLGGSREQIQNAVSNAWIDNAPLRTYRHAPNTGSRKSWAAGDATSRAVWL 236
108805205 146 GVLALENAFNRVGLDHVLLVRVASAAVATRLLGGGREEVESAVSGAFIDGGPLRTYRHAPNVGSRKSWAAGDATSRGVRL 225
297621694 148 GCLSLENSFNRVGLDHVLLVKVATAALATKLLGGDEKQIQDALSQAWIDIGPLRTYRHAPNTGSRKSWAAGDAARRGVQL 227
93006130  241 VDITRRGEMGIPSALTAPQWGFYDVLFShtnkdlalkpenERCFTFQREFGSYVMENILFKISFPAEFHAQTACEAAVIL 320
305675061 228 ALMALKGEMGYPTALSAPGWGFQDVLFN------------KQEIKLARSLDAYVMENVLFKVSYPAEFHAQTAAECAVIL 295
56963571  234 AMTALTGEMGYKTALSAPGWGFQDVLFN------------KKEVVLARKLDSYVMENVLFKVSYPAEFHAQTAAEAAVTL 301
154686672 231 ALMAHKGEMGYPTALTASGWGFQDVLFN------------RREIKLARPLGSYVMENVLFKVSYPAEFHAQTAAECAVRL 298
52082382  235 AMMTLKGEMGYKTALSAPMWGFQDVLFG------------GKELTLARPLDSYVIENVLFKISYPAEFHAQTAAEAAIRL 302
52787772  235 AMMTLKGEMGYKTALSAPMWGFQDVLFG------------GKELTLARPLDSYVIENVLFKISYPAEFHAQTAAEAAIRL 302
157692616 234 AMMTLKGEMGYQTPLSAEKWGFEDVLMK------------GKSLTLAQPLGSYVIENVLFKIAYPAEFHAQTAAEAAMIL 301
258510797 237 AFMALRDEMGYPSALTAPQWGFSDVVMG------------GKPIVLARPLGSYVMENVLLKISFPAEFHAQTAVECAFQL 304
108805205 226 AMMAVSGEMSYPKALSAEGWGFQDALFG------------GKEIELARPFGSYVMENVLFKISFPAEFHAQTAAEAALRL 293
297621694 228 AWITLQGEEGYSTPLTAPYWGLNDVLMK------------ENPIQLKGNLGSYVMENVLFKIAFPAEFHAQTAVEAAIQL 295
93006130  321 HPRIDDRMEDIEKIILTTHESAIRIISKEGTLANPADRDHCLQYMVAVALLTGDLMAENYEDDYhAEHHiLIDGLRHKMV 400
305675061 296 HPQVKCRIDEIDRVVIRTHESAIRIIDKKGPLHNPADRDHCLQYITAIGLLFGDITAQHYEAET-ASDP-RIDKLRDKME 373
56963571  302 HESVRDRLDEIDRIEIHTHESAIRIIDKKGPLYNPADRDHCLQYITAIGLLKGAIVADDYEDEM-AQDP-RVDQLRDLMV 379
154686672 299 HPEVKDRIEDIDRITIMTHESAIRIIDKKGPLHNPADRDHCLQYITAIGLLFGDITADHYEEET-ASDP-RIDTLRSKME 376
52082382  303 HPEVKDRLDDIGQIVITTHESAIRIIDKTGELHNPADRDHCLQYITAIGLIYGDITADHYEDET-AQNP-EIDRLREKMT 380
52787772  303 HPEVKDRLDDIGQIVITTHESAIRIIDKTGELHNPADRDHCLQYITAIGLIYGDITADHYEDET-AQNP-EIDRLREKMT 380
157692616 302 HDAVKDRLDEIDRVEITTHESAIRIIDKKGPLYNPADRDHCLQYITAIGLIYGELTADHYEEET-AQNP-AIDRLRDQMV 379
258510797 305 HPLVKDRLDEIERIVITTHESAIRIIDKKGPLHNPADRDHCIQYMVAVGLIYGDLRAEHYEDET-ASDP-RIDALREKME 382
108805205 294 HPEVRDRLGEIERVEITTQEPAMRIIAKEGPLNNPADRDHCIQYITAVGLIFGEITADSYEDSF-AKDP-RIDELRAKTT 371
297621694 296 YPDVKKKWDQIEKIEIHTHESAIRIIDKKGPLRGPADRDHCLQYIVAIGLLFGELTADHYEDKI-AQDP-RINALREKMT 373
93006130  401 VEEDAGYSKDYHDPSKRSIANAIQVFFKDGSSTDKVAIEYPIGHKRRRTEGLPILEAKFRASLATRFIDSRCTEIFALCS 480
305675061 374 VTENKTYTEDYLKPDKRSISNAVQVHFKDGTSTEMVECEFPLGHRFRRDEAVPKLLEKFSANLKTHYADKQHKHIYERCT 453
56963571  380 VTENKQFSIDYLDPEKRSIANAVQVFFKDGTKTDQVTIEYPLGHRFRREEAVPAIQEKFAANIASHYPQKQEKAILEACT 459
154686672 377 VTEHKAYSKDYLDPNKRSISNAVQVHFTDGTATGRIECEYPLGHRFRRKEAVPKILAKFSANISTHFSLKQQRKIEEACE 456
52082382  381 TVENKQYSVDYLDPEKRSIANAVQVFYKDGTHSEKIAVEYPIGHRRRRNEGIPLLKDKFINNLKTRFPAGQAERINALLN 460
52787772  381 TVENKQYSVDYLDPEKRSIANAVQVFYKDGTHSEKIAVEYPIGHRRRRNEGIPLLKDKFINNLKTRFPAGQAERINALLN 460
157692616 380 VKEDTQYTADYLDPKKRSIANSVQIFFKDGTMTDRIEIEYPLGHRRRRQEGIPLLEKKWIYHLKTRFPQKQVDHIVSLCQ 459
258510797 383 VVEDPRYSKDYLDPDKRSIANAVQIFFRDGSHTDKVEVEYPIGHRRRRAEGLPKVIEKFRANLLTRFPEKRAERILDLCL 462
108805205 372 VAEDERYSRDYLDPDKRSIANAVQVFFRDGSSTEKVEVEYPIGHRRRREEGIPLLEEKFRANAATRLPKKKLSALKELFS 451
297621694 374 VIEKPRYSKEYLDPRLRSIANALTIYMKDGKSLGPVEVEYPLGHRKRREEGTPLLYKKCEQNLSTCFKKGKVQELMQLFH 453
93006130  481 DQQRLEQTPVNEFMDLFVA 499
305675061 454 SYETLQTMRVNEFVDMFCM 472
56963571  460 NKD-LGNMSVPAFTDLLAL 477
154686672 457 HSGRMQKLSVSEFMDLFLV 475
52082382  461 DPHRLSGAPVPDFMELFVI 479
52787772  461 DPHRLSGAPVPDFMELFVI 479
157692616 460 NPNQLKTTTVPAFMDLFVI 478
258510797 463 DAERLHETPVDEFMELFVI 481
108805205 452 EQGRLEETPVDELMGLLAM 470
297621694 454 DQESFEGLRISELMNRLAG 472
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