2XMX


Conserved Protein Domain Family
Colicin_M
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pfam14859: Colicin_M 
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Colicin M
Colicin M is a toxin produced by, and active against, Escherichia coli. It catalyzes the hydrolysis of lipid I and lipid II peptidoglycan intermediates, therefore inhibiting peptidoglycan biosynthesis and leading to lysis of the bacterial cells.
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Statistics
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PSSM-Id: 258996
Aligned: 3 rows
Threshold Bit Score: 429.085
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2XMX_A     3 TLTVhapsPSTNLPSYGNGAFSLSAPHVPGAGPLLVQVV------YSFFQSPNMCLQALTQLEDYIKKHGASNpltlqII 76 
ACO91757   3 TLTVhapsPSTNLPSYGNGAFSLSAPHVPGAGPLLVQVV------YSFFQSPNMCLQALTQLEDYIKKHGASNpltlqII 76 
ACH86130   2 EFEL----PATYVYPDEYGTSRSTGFTVPSPGAIVNRMVqersaaYARGDWAPMLERHLHAMHSNKPAYGLDG-----FI 72 

2XMX_A    77 STNIGYFCNADRNLVLHPGISVYDAYH--FAKPAPSQYDYRSMNMKQMSGNVTTPIVALAHYLWGNGAERSVNIANIGLK 154
ACO91757  77 STNIGYFCNADRNLVLHPGISVYDAYH--FSKPAPSQYDYRSMNMKQMSGNVTTPIVALAHYLWGNGAERSVNIANIGLK 154
ACH86130  73 MGDLKVAHGADLLLLKNPKLSTADAWNqgIKEGSKIQNNAQLAVPTEFSGGTFTPFKAIQHWLLGNGNTASVQISRIGIN 152

2XMX_A   155 ISPMKINQIKDIIKSGVVGTFPVSTKFTHATGDYNVITGAYLGNITLKTEGTLTISANGSWTYNGVVRSYDDKYDFNAST 234
ACO91757 155 ISPMKINQIKDIIKSGVVGTFPVSTKFTHATGDYNVITGAYLGNITLKTEGTLTISANGSWTYNGVVRSYDDKYDFNAST 234
ACH86130 153 PTPEKIPDLMAIINTARIGETTVNFNTSYYTGQDSVIPRIYLGTITLNITGKITRNTSGTVSFSGVVKAFSDRYDANASS 232

2XMX_A   235 HRGIIGESLT----RLGAMFSGKEYQILLPGEIHIkeSGKR 271
ACO91757 235 HRGVIGESLT----RLGAMFSGKEYQILLPGEIHIkeSGKR 271
ACH86130 233 HRTGFDEAATtalrEVGRVANAKDYAIQINGELPI--SYAR 271
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