Conserved Protein Domain Family
NleF_casp_inhib
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pfam16809: NleF_casp_inhib 
NleF caspase inhibitor
Binds to and inhibits caspase-9, caspase-8 and caspase-4. therefore preventing caspase-induced apoptosis in the host cell.
Links
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Statistics
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PSSM-Id: 293414
Aligned: 4 rows
Threshold Bit Score: 163.094
Created: 22-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4_pfamImport   1 NKNIINAETQHTINDIKQKLSLIQERYNASTTAEFYFVE---------NQLTDMHESISQRKEDLYEP-EDYSLSGVQER 70 
3_pfamImport   1 NKDIKTEETEQFLEEIDAQMKVICAWEMDSTTVDQCIKEl-------cDKIGALYNDVLTTRSQVYEMvLNYGTESGQMV 73 
1_pfamImport   1 DKNRLTLEQEKGLKDIKSSIDDCYHNGISTSTGRKKIKEl-------rNKVTQYINSVESYRDKIYDViIDKRTGRGEKI 73 
2_pfamImport   1 KYNKIDQDTQETLKNINDKLHRAF-----LLTSPEQIEEkqkiidavsDDLEKMKRNVLSERGDLYCG-EEVKLHGKMRT 74 

4_pfamImport  71 ELKKGKTAQDRNNLVKDLVALYQIKNAIKEMIpeDKTKTIDDYSTYYPKPIHNGKVldihhpfyslveesvkhklFSDLY 150
3_pfamImport  74 RLREGCNAADRDRYLEKLIAYNHIRQAVSDKV--AKIEKHTDSVKRMVDLHHYDYI-------------------CGDLK 132
1_pfamImport  74 ILKSGCDETHRNSYLKGIIYLSKLQDLIRNEIdnAPIK-YKKSLSKVFDVMGKGAV-------------------YGDIK 133
2_pfamImport  75 TLSEHITVERRDNFIKSLVNLYQIVRGVKATItnAPNNTISSLINSNANESYNGLVqvd-------------avlARDFN 141

4_pfamImport 151 AIENNRKVPYV 161
3_pfamImport 133 ALNKNGDVPKQ 143
1_pfamImport 134 ALNEDRKLPDF 144
2_pfamImport 142 AIEKNNRVPNV 152
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