Conserved Protein Domain Family
Cas6e

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COG5934: Cas6e 
CRISPR-Cas system endoribonuclease Cas6e, RAMP superfamily [Defense mechanisms]
CRISPR-Cas system endoribonuclease Cas6e, RAMP superfamily is part of the Pathway/BioSystem: CRISPR-Cas system
Statistics
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PSSM-Id: 444632
Aligned: 110 rows
Threshold Bit Score: 311.404
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_111331838   3 DAKFLQIHTLTSYPGTLLNRDDAGFAKRMPFGGATRTRVSSQCLKYHWRNFdgegaLYKMeFEePVRSIRSRTTFRDlVA 82 
WP_012226055   1 MSRFLQLHLLTFYPPSNVNRDDTGNPKTANVGGVTRLRISSQALKRAWRTSe---iFSSA-LA-GHMGQRTQRLGNE-IR 74 
WP_015931865   1 MTTFFQLHVLTAYPPANLNRDDTGRPKTARVGNVDRLRVSSQALKRAWRSSd---aFAEA-LA-GHLGQRTQRLGET-IE 74 
WP_012969876   3 TRNFVNFHVLISHSPSCLNRDDMNMQKTAIFGGKTRVRISSQSLKRAIRYSd---yYARY-F--ISKSQRTRRLFDK-MA 75 
WP_013170925   1 MSKNITIHCVANVPHSNLNRDDSGTPKRLMQGGALRAMHSSQSIKRGIRGK-----YEEAsL---DISVRSGKLVDE-VI 71 
WP_005223767   3 RPNFVNLHVLISHSPSCLNRDDMGQQKTAIFGGKTRVRISSQSLKRAFRFSd---tYRQA-F---SRSTRTRRLLDQ-LV 74 
WP_014415273   1 MTTFVQIHALTAYPAANLNRDDSGRPKTVTMGGVPRLRVSSQSLKRAWRTSd---aFQQA-LD-GHLGQRTKRLGDEvVL 75 
WP_041794690   1 --MKLDFHVLTVYPPHNVNRDEDGRPKTAMFGGTVRGRISSQAKKRAIRLSp---hFQDL-----QRATRTRKTGII-TW 69 
WP_015072150   1 MSRFLQLHLLTFFPPSNLNRDDLGRPKTAMVGGANRLRLSSQALKRAWRTSe---aFEAT-LE-HHLGKRTQRMGQE-IL 74 
WP_066819158   1 MTTFLQLHLLTTYPPSNPNRDDQGRPKSAMLGGAPRLRLSSQSVKRALRMSd---aFQQG-LA-GHLGQRTKLIGNV-VR 74 
WP_111331838  83 KPMIER-G---LPERLVVATVET-FVQRLm--Sd--DAP--------------SAAdykaslms------asspeepLID 133
WP_012226055  75 QHLLEK-G---LDEKRSLAIARD-IAGIY---G---KVKa------------eKD-----------------------AN 108
WP_015931865  75 GHLIDR-G---ADPATARTAARA-VAERF---G---KLKs------------eGD-----------------------KK 108
WP_012969876  76 DELSAS-AesaEQTTAIEKCALY-AAAIFe--G---KTKi------------dEIGkye----------------rdKKS 120
WP_013170925  72 DMISSL-Np-eADAKSYQKAAAKr----I---GeltKGS---------------------------------------SS 103
WP_005223767  75 ADLDPDsG---IDAAAFEQCALY-VAAIFe--G---KTKe------------aEIQry-----------------vrAKS 116
WP_014415273  76 PHLLDR-G---MTRERAEAVAKA-IADVF---G---KLEg------------dD------------------------KN 108
WP_041794690  70 RALGEA-G---VEDEKIRILAALsVNFALgggGk--KPQkktvaeflkaleekKSRdniariqaeqacdektarlyvLEE 143
WP_015072150  75 DHLIAA-G---QDVKKATKIARE-VAGIF---G---KLKk------------eE-------------------------T 106
WP_066819158  75 EHLEGQ-G---AKTEAARKVAET-VAAAF---G---KIEt------------aDKT---------------------RPD 110
WP_111331838 134 RLKTNQVTIFGEPELRYIIKASAELIaemkpelgelwENPamKLSKEqvkvvtdtlgklkkgdlkKN--IKGMKl--ASG 209
WP_012226055 109 STYTEQLVFISPAEREAAFAMADRLA-----------AGE--KIDLA------------------KEk-DALLYr-tDTA 155
WP_015931865 109 PTHIEQLAFISADERKAAFALAERLA-----------AGE--TVDVDk---------------------APLLRr-aDGA 153
WP_012969876 121 DHIETQIIPFSCAEIEGIKQILLEAA-----------GKP--EKGRIeymk-----------aeiQR--LEREQr-tRID 173
WP_013170925 104 EAESDRSAWLSVEECTTLAQSLLDGD---------------------------------------EN--ATFIHngkTGS 142
WP_005223767 117 GHIETQIIPFSSHEIEAIGGLLREAAa----------LAT--EKARIthlk-----------qavKE--LEQRLr-hQLD 170
WP_014415273 109 PLHLRQLAFISPEERAAALALADRAL-----------AGE--AVEKE------------------KIpaDAVLRr-aDTA 156
WP_041794690 144 ELRSAQALVISTKEMVKLDAWTKTLA-----------AAC--REAGQnawkkaet---lcaelceKK---SLLSk-eDLD 203
WP_015072150 107 STAIEQLAFISPREKAAALELADRMA-----------GGE--KIDPK------------------KEa-ASVLLr-aDTA 153
WP_066819158 111 WVQGTTLAFISPQERSFALELADRLA-----------AGE--PAPNG------------------KElaKAVLRt-aDGA 158
WP_111331838 210 LDAALFGRMVTSDVLSRGDAAIHVAHAFTVHEEA-SESDYFAAIDELRR--DSGELGGGHINSSELTSGLYYGYTVIDVP 286
WP_012226055 156 ADIALFGRMLASEPSYNREAAVQVAHAITTHRVT-VEDDYYTAIDDLKR--PEEDAGAGFLSEAGFGSGVFYLYLCVNRE 232
WP_015931865 154 VDVAMFGRMLADSPEFNREAAVQVAHAFTTHRAP-VEDDYYTAVDDLKG--PQEDAGAGFVGEAGFGSGLFYLYVCIDRD 230
WP_012969876 174 LDVALSGRMANSELIYPVDGALAVAHAITTHTVEpQDIDWFTAVDDLTL--DAGETGAGHLNTQQFSAGVFYRYASLNLR 251
WP_013170925 143 LAIAAFGRMFANAQEKNTEAAIAVSPGVTTHAAT-IESDYFSTGDDVRE--RNNESGATYLGVARYVNGTFYRTISIDKD 219
WP_005223767 171 LDVALSGRMANSELIHGVDGALAVAHALTTHTVEpQDIDWFTAVDDLTQ--DAGESGAGHLNVQQFSAGVFYRYASLNLR 248
WP_014415273 157 ADIAMFGRMLADDPRYNREAAVQVAHAITTHRVV-VEDDYFTAVDDLKAegDADDTGAGHVGVQEFGSGLFYLYACINRD 235
WP_041794690 204 EDTVLFGRMVAADAKHNVEATSMVSHAITTHRFS-IEGDYFSAAEELKD---LGETGAAHTSYAFFGSGVYYQHAVLDVG 279
WP_015072150 154 ADIALFGRMLADNPSFNREAAAQVAHAITTHKVS-IEDDYYTAVDDLKT--SSEDAGAGFLGEAGFGSGVFYLYLCINRD 230
WP_066819158 159 VDIAMFGRMLADNPDFNRDAAVQVSHAITTHAAQ-IEDDFFTAVDDLKK--RDEDAGGAHLGEHAFGSGVFYLYACVNCD 235
WP_111331838 287 LLISNL--EGcared---wksaDRTLAAQVVERFVKLQATVSPGAKLGSTAPYAWAECVLVEAGSAQPRTLANAFRRPVR 361
WP_012226055 233 LLRKNLgdAD------------ESGVMETALGALVEAAATVAPSGKQNSFAALARAQYVLAERGNAQPRTLAGAFARPVA 300
WP_015931865 231 LLVRNL--AG------------DEDLARAGLSAVVRAVTTVAPRGKQASFASRARASFGLLERGSEMPRTLAAAFLKPVG 296
WP_012969876 252 QLQFNL---GllaninaeqtteSRARALDIARHVLHLLATVVPSAKQQSFAAHNLADFVIVSLA-DQPVSLANAFEEPIE 327
WP_013170925 220 QLKKSW--AGy-----------GVEGCRENLREFIRACVYGMPRGKENSTAPYTLPSLVLVE---EQRYRSAYTFEKPVK 283
WP_005223767 249 QLQYNL---GlldtidapetaaGRARALAIAAHVLQLMTTVVPEAKQQSFAAHNIADCALVSLA-DQPISLANAFESPVP 324
WP_014415273 236 LLRANL--KG------------DTGLADTAEQALVRAMATVVPKGKINAFAHHTRASLVLVEHGHFQPRGLSTAFLKPVR 301
WP_041794690 280 ALCQSL---Gk-------------DRARQAALAFVNGLLAAQPGGKRNSYASDVLAAYLLCSRGTAPSFNAALAFLEPVV 343
WP_015072150 231 LLKTNLgeED------------DGTLAAATLGALTRAAATVAPSGKQNSFAAHARAHYILAEKGNQQPRTLAGAFAQPVT 298
WP_066819158 236 LLVENL--GG------------DAALAAKGAEALVRALATATPSGKQSSHAHRPRAGYIRAEVGQDAPRDLSGAFFTAVT 301
WP_111331838 362 e---QPDVLENAYQALGSYVHGIDQMYGHSGe-RRLsVS--SdaagladaLGVea-pVS------LPNSAQWAAE 423
WP_012226055 301 ----GTDLMAGSIAALRTFRGELARVYGAGId-AECeLEtaR--------KDS----AT------LADIAAFCRS 352
WP_015931865 297 ----GEDVLETSIARLLSLRESFARAYGDEAe-TAI-MNv-P--------AGE----GS------LADLIALAVR 346
WP_012969876 328 rerkIGGFLQPSITALADYWSRVNSAYGLDEqaRAF--Al-Rgg----ikLGDqevlTS------IADLEQWLAN 389
WP_013170925 284 vg-aEGGYEEETIKELDRQFGR-ARSFDPGNfgPLEiVSgtAdlad-eafAGVq--rAS------LDAMIDSVVD 347
WP_005223767 325 kd-rEGGYLRPSIETMLDYWRRLNRAYGLNEtaRVF--Tl-Dda----taETPph-lDT------LPALQTWLRE 384
WP_014415273 302 ----GETIMSESIQALKAQRHAFDTAYGETPa-HAV-LDt-Tgvw--derSATv---TS------LEALLAFVKE 358
WP_041794690 344 pe-kGQDLLAVSAKRLREYYDTVRTAYDLSLepLIFaAA--Psl-----rEGNa---PTapevwtVDAVHRFVAE 407
WP_015072150 299 ----GTDIVGASIAQLKTFRDQLENAYGPGSd-AQAeLv--L--------GGG----GT------LEEIVTFAQK 348
WP_066819158 302 ----GGDLLAASVERLETMAAQIDRAYGPACe-AAEvMNv-A--------AGQ----GT------LAALMAFAGA 352
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