2BSH,2BHO,2BSJ


Conserved Protein Domain Family
T3SC_IA_SycT-like

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cd17032: T3SC_IA_SycT-like 
Click on image for an interactive view with Cn3D
Class IA type III secretion system chaperone protein, similar to Yersinia enterocolitica SycT
This family includes type III secretion system (T3SS) chaperone proteins similar to Yersinia enterocolitica SycT and similar proteins. In Y. enterocolitica, a food-borne pathogen causing gastroenteritis and mesenteric lymphadenitis, chaperone SycT promotes translocation of effector YopT (Yersinia outer protein T), a cysteine protease that inactivates the small GTPase RhoA of targeted host cells by cleaving its C-terminal, prenylated cysteine, thereby releasing the GTPase into the host cytosol.
Statistics
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PSSM-Id: 409316
Aligned: 6 rows
Threshold Bit Score: 183.854
Created: 4-Feb-2016
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
 
dimer interface
Conserved site includes 19 residues -Click on image for an interactive view with Cn3D
Feature 1:dimer interface [polypeptide binding site]
Evidence:
  • Structure:2BSH: Yersinia enterocolitica type III secretion system chaperone SycT homodimer; contacts at 4.0A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                 #   # # #               ####   ### # ##
2BSH_A         5 QTTFTELXQQLFLKLGLNHQVNENDVYTFEVDGHIQVLIACYHQQWVQLFSELG-----ADLPTNDNLFGEHWPAHVQGR 79  Yersinia entero...
2BHO_A         2 QTTFTELMQQLFLKLGLNHQVNENDVYTFEVDGHIQVLIACYHQQWVQLFSELG-----ADLPTNDNLFGEHWPAHVQGR 76  Yersinia entero...
Q7N0U0         2 THDYHQLIEALFSKLGVPASPTEDGIYTLEVDGRFQVLIGCYHDNWLQLFCELG-----SEISHANNLFGQHWPAHVQGD 76  Photorhabdus lu...
KIP68355       2 TTTFDHLVKHFFEKNGLENPTAQDGIYSLLIDQKYQLHFTHQNEEWMVLYAELGeanpiSELLAKSNIFGEYWPAHIVSH 81  Vibrio harveyi
WP_051228906   1 MSLFDDLLLRLHLRSGFAFDTCEETMVSLRCGDGLRVYLAAYQDRWLVLYHELDg---dCGPVTPDNLFGRHWPAHVLSP 77  Paludibacterium...
2BSJ_A         5 QTTFTELMQQLFLKLGLNHQVNENDVYTFEVDGHIQVLIACYHQQWVQLFSELG-----ADLPTNDNLFGEHWPAHVQGR 79  Yersinia entero...
Feature 1             # # ##  #                                
2BSH_A        80 LDGKSILWSQQSLVGLDIDEXQAWLERFIDDIEQRKEPQNTKFQPN 125 Yersinia enterocolitica
2BHO_A        77 LDGKPILWSQQSLVGLDIDEMQAWLERFIDDIEQRKEPQNTKFQPN 122 Yersinia enterocolitica
Q7N0U0        77 LDGQAILWSQRPLGEVDVAELQAWLERFIDDIEQRLTPNTTQQPKN 122 Photorhabdus luminescens subsp. laumondii
KIP68355      82 QENSAVLWSQQPMAMLNVAALEAWTECFIQDLIEKQAAISGVEPTP 127 Vibrio harveyi
WP_051228906  78 VDGIWILWSQQPLAGLSEHALECWVSDFAASVARYRSPAAATEKAR 123 Paludibacterium yongneupense
2BSJ_A        80 LDGKSILWSQQSLVGLDIDEMQAWLERFIDDIEQRKEPQNTKFQPN 125 Yersinia enterocolitica

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