Conserved Protein Domain Family
Terminase_2

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pfam03592: Terminase_2 
Terminase small subunit
Packaging of double-stranded viral DNA concatemers requires interaction of the prohead with virus DNA. This process is mediated by a phage-encoded DNA recognition and terminase protein. The terminase enzymes described so far, which are hetero-oligomers composed of a small and a large subunit, do not have a significant level of sequence homology. The small terminase subunit is thought to form a nucleoprotein structure that helps to position the terminase large subunit at the packaging initiation site.
Statistics
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PSSM-Id: 427384
Aligned: 40 rows
Threshold Bit Score: 60.0574
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
PRJNA194094:J421_4674   8 LTPKQQRFVEEFIVD-LNATQAAIRAGYSARV---AANIGYENLQKPQIAAAIREAKAARSLRTQIEADDVLQRW---WD 80 
BAK60596                3 LTKKQQDFADYYIEL-GSAEEAAIKAGYSKNY---ARASAYKLLANVGIKKYIDKQITKMASERIMGAQEILERL---TL 75 
WP_011101755            5 LTPKQQKFADEYIKS-GNATQSAILAGYKKRS---ARSVGQENLTKPDIKKYIDEQMAEIESSKIADAKEVMEFY---TR 77  Lactip...
WP_011722253            3 LTPKQKAFADYYIQL-GNATEAAIKAGYNKKT---ARQIGSMNLTKVDIKNYIQERMTQLEDKRIAKAEEVLQYL---TR 75  Clostr...
WP_020457818            3 LTEKQKAFCDYYIET-LNATESYKKAGYKVKTdgaARVNASRLLTNANVRKYIEERMKQKESERIASQDEVLEFL---TR 78  Acetiv...
CDC21614                1 MTPKEKKFADEWLID-CNGTRAYMAAYPNVKNnksAGVLANKLLAKASVRQYVDGKLAELSSKKIASAEEVMEYL---TS 76 
Q3ABI3                  4 LTEKQKRFIDYYIET-GNAAEAARRAGYKGKN---LDVIGSQNLVKLRI--YIEEKMKQKDNERIASQDEVLEFL---TR 74  Carbox...
Q2FX50                  1 MNEKQKRFADEYIMNgCNGKKAAITAGYSKKT---AESLASRLLRNVNVSEYIKERLEQIQEERLMSITEALALS---AS 74  Staphy...
AAK33878               13 LTEKQQRFVDKYITT-FNATESAKQAGYSEKS---AYSQGQRLLKNVEIQKAMKERFLEAKDTKGDRIQDVAETLeqdTS 88 
Q65PP8                  4 LTPKQKKFCQEYLKD-FNASR-AYKAVYKVKSdnqARANGSRLIANDNVSEYLSETMHQTKVNDILDINGVLDNL---SQ 78  Lactob...
PRJNA194094:J421_4674  81 LANANPNELVEvqrrscrychgrggmyqrtavelqrdrakydleraawerkkkraadafpafdeqggigydprrdpnpkc 160
BAK60596               76 IAKAEITETVVvanad---------------------------------------------------------------- 91 
WP_011101755           78 VLRGEELETVVvgtad---------------------------------------------------------------- 93  Lactip...
WP_011722253           76 VVRGEENEPLAvqeqepvigedg--------------------------------------------------------- 98  Clostr...
WP_020457818           79 VMRGQEVEEVVgftey---------------------------------------------------------------- 94  Acetiv...
CDC21614               77 VLRGVSSAEVIvvegigdg------------------------------------------------------------- 95 
Q3ABI3                 75 VMRGLETEEVVvtenkgdy------------------------------------------------------------- 93  Carbox...
Q2FX50                 75 IARGEPQEAYS--------------------------------------------------------------------- 85  Staphy...
AAK33878               89 IARGEI-------------------------------------------------------------------------- 94 
Q65PP8                 79 LAIGKPREKVF--------------------------------------------------------------------- 89  Lactob...
PRJNA194094:J421_4674 161 qrcwgdgvARVLVKDTRRLSPAALRLYAGvkeTQh---------------GVDVRMRDQDGALLNVAKH---L------- 215
BAK60596               92 ---------------------------------------------gyaevEKPPDFKTQIQAMKELLKR---Ypgndkll 123
WP_011101755           94 ---------------------------------------------gaesiERPPTTKDKTAVAKEILKR---Ypgndklv 125 Lactip...
WP_011722253           99 --------------------------------------kkkgyrtvtkviNIGPNIKDRNKAAELLGKR---Y------- 130 Clostr...
WP_020457818           95 ---------------------------------------------gavkeKKTPSARDRVKAAELLGKR---Y------- 119 Acetiv...
CDC21614               96 -------------------------------------------ysearavQKKPDEKEKLKAAELLGKR---Y------- 122
Q3ABI3                 94 -------------------------------------------iseakiiKKQVSAKDRVKAAELLGKR---Y------- 120 Carbox...
Q2FX50                 86 -------------KKYDHLNDEVEKEVTY---------------------TITPTFEERQRSIDHILKVhgaYidkkeit 131 Staphy...
AAK33878               95 --------QISEFKETDMLTGQVVIHTKR---------------------EYTPSHEEQGRARDRIYKVngaYsekrele 145
Q65PP8                 90 --------------------------------KRisykgkkpkveydnvtTVTPEDQDQLKALELLGKY---Y------- 127 Lactob...
PRJNA194094:J421_4674 216 --GMlvERvetRDKTIE 230
BAK60596              124 eqTL-------RKLTAE 133
WP_011101755          126 eqQI-------RKLKAE 135 Lactiplantibacillus plantarum
WP_011722253          131 --RL-------FTEKVE 138 Clostridium
WP_020457818          120 --AL-------FTEKVN 127 Acetivibrio thermocellus
CDC21614              123 --GL-------FTDKLE 130
Q3ABI3                121 --AL-------FTEKVN 128 Carboxydothermus hydrogenoformans Z-2901
Q2FX50                132 qkNIeiNIgeyddes-- 146 Staphylococcus aureus subsp. aureus NCTC 8325
AAK33878              146 hsGTvvFAnednipd-- 160
Q65PP8                128 --KI--FT---DKV--E 135 Lactobacillus johnsonii
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