Conserved Protein Domain Family
PRK06556

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PRK06556: PRK06556 
vitamin B12-dependent ribonucleotide reductase; Validated
Statistics
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PSSM-Id: 235828
Aligned: 42 rows
Threshold Bit Score: 1433.22
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
28210310     1 MKLLNNLDNTDFLNKIIRRKFTkelekNKNLTVYDLFNWKLVDVFLKDhKTGKVLVDMKDLEFPEHYSQNSCDIIASKYF 80  
296123412   29 FPMGTSRPLPEAAPMRIRPEFC-----PEGVDPFSTSEWELRSAFIKD-ENGKVLFEQKDCEIPAHWSPLATNVVVSKYF 102 
283778372   16 GMKKIDAIRELQKGLRVEPTFCp----ADLADPFDSVNWELRSAQIKD-ENGKLMFEQTDVEIPAGWTQLATNVIVSKYF 90  
15894334     1 ---------MEDLKILFKRFYTkelesSKTKTVYDLFKWKKVDVKIIDhKTGKVLTDMKDLEFPYDYSQNACDIIASKYF 71  
300853872    1 ---------MDCVKDLFKRYFTkslkqNNNKTVYDLFKWKKVDVFLKDhKTGKVLVDMKNLEFPENYSQNACDIIASKYF 71  
225873206   14 AQPQAQPHTASTPALRFGRLFS-----RPGVSPYDEVQWESRTAAITD-AAGKTIFEQKDVEIPVDWSMTATNIVASKYL 87  
86158038    11 PRASKSAKKVAKKGLSVERYFT-----TPGVDPAEELAWETRTAAITG-EGGATIFEQKDVEVPKSWSLLATNVVASKYF 84  
262198687   19 QAESKRARAQDRPGFEVSRYFT-----SEGVDPYSEVEWELRDATITG-ANGKVYFEQKQVEFPKAWSQTATNVVVQKYF 92  
32477697    34 REKFGTALRGDRAGLKFESKFCp----DDGRTPFATTAWDLRSAAIKD-ESGNALFEQTDCEVPASWSQLATNVVVSKYF 108 
116620784   13 ESLKTRTPKKNKTGISFPRHFTak--lESGKTPYDEIQWETRTASIGN-DKGSVIFEQRDVEVPVDWSQTATNIVASKYF 89  
28210310    81 RKA--GVPNKygyENSMKMVAHRMVNFWASALHEQGLLKTKDEKQIFYDEMVYALLSQMYAPNSPQWFNTGLcMeygikg 158 
296123412  103 YGEh-GTSER---ETSVRQVINRVARTIADWGIADGYFASREDGENFYNELAWLCLHQYGSFNSPVWFNVGL-Yhqygva 177 
283778372   91 YGEn-GTAER---ERSVKQLIHRVTRTIADWGIEDGYFASAEDGEQFYRELTWLCLNQHGAFNSPVWFNVGL-Fnqygvt 165 
15894334    72 KKS--GIPNEcgyENSMKMVAHRLVSFWCEALKDEGIIKTENEASIFYDELVYALLNQMYAPNSPQWFNTGLsLiyging 149 
300853872   72 RKA--GVPGEngyENSMKSVTHRMVNFWCESLKDEGLIKTEDESSIFYDECAYALLNQMCAPNSPQWFNTGLkLsydicg 149 
225873206   88 HGPl-NTPER---ESGVRQLVSRVAETVRDWGIKGGYFASEEDAAIFHDELAHLLITQKAAFNSPVWFNVGC-Drlepks 162 
86158038    85 RGQl-GTPAR---ERSVRQLVSRVVETIGAWGRKDGYFTTEADAATFEAELAHLIYRQKMSFNSPVWFNVGV-E------ 153 
262198687   93 RGTv-GTPER---ERSVKQMIGRVADTIFGWGRKDGYFRSDKDAWRFRDELVHLLVNQKMAFNSPVWFNVGV-E------ 161 
32477697   109 YGDpkNTDER---ERSVRQLIHRVTRTISDWGLADGYFDTPEDGERFYRDLTWLSLHQHGAFNSPVWFNVGL-Haqydve 184 
116620784   90 YGKl-GSPDR---ETSVQQLVQRVVDTITDWGKKDGYFKTEQDGENFRMELAHLMLTQKACFNSPVWFNVGVkEtrgygw 165 
28210310   159 spngnyyydenlkqvvesvdsySRTQASACFILSIEDKLlgsHSISDQYVNETKLFKGGSGTGTNFSTIRAKGEKLSGGG 238 
296123412  178 gskgnyrfdlktqevvraetsyEFPQASACFIQSVDDNM---EDIMRLATSEAMLFKFGSGTGTDLSSIRSAKEKLSGGG 254 
283778372  166 gakcnwrwnpetgtteqpenpyEYPQGSACFIQSVDDNM---EAIMRLATSEAMLFKFGSGTGTDLSTLRSHREKLSGGG 242 
15894334   150 eaqghfyydskekkvlqskdsyTRTQASACFIISIEDKLlgsHSISEQYVTETKLFKGGSGTGTNFSTIRAKGEKLSGGG 229 
300853872  150 akqgnyyfdenlnkvveskdnyTRTQASACFILSIEDKLlgsHSISNQFVTETKLFKGGSGTGTNFSTIRAKGEKLSGGG 229 
225873206  163 daqnwhwn-phtcavefsvtgyRNPQCSACFINAVDDSL---DSILTLAKTEGMLFKWGSGTGTNLSPIRGSMEQLSGGG 238 
86158038   154 ----------------------EHPQCSACFINAVGDSM---DSILKLAHTEGMLFKYGSGTGSNLSKIRSSKERLSGGG 208 
262198687  162 ----------------------TEPQCSACFINSVDDSM---SSILTLARTEGMLFKYGSGTGSNLSSLRSSAENLHGGG 216 
32477697   185 gdmcnwhwdrtenttaqpdnpyEYPQGSACFIQSVDDNM---EDIMRLACSEAMLFKFGSGTGTDLSTIRSQREKLSGGG 261 
116620784  166 nyder------vgkvtkletgvMRPQCSACFIVSVKDSL---ESILDLAKTEGMLFKWGSGTGSNLSALREEDAVLSGGG 236 
28210310   239 VSSGLMSFLKGLDRNAGAIKSGGTTRRAAKMVCLDIDHPEILDFITWKAREEDKVRALG-KMGYDMDID--GEAYETVSG 315 
296123412  255 TPSGPLSFMRVYDQIAAVVKSGGKTRRAAKMQSLKDWHPDILEFIQCKLKEEKKARVLIeSGEYDSNFN--GEAYGSIMY 332 
283778372  243 KPSGPLSFMRVYDQIAAVVKSGGKTRRAAKMQSLKVWHPDILEFVECKWKEERKAHVLIeKGGYEANFN--GEAYSSILF 320 
15894334   230 ISSGLMSFLKGLDRNAGAIKSGGTTRRAAKMLCLNVDHPEIMDYITWKAKEEDKVKALG-KMGYDASFE--GEAYETVSG 306 
300853872  230 SSSGLMSFLKALDKNAGAIKSGGTTRRAAKMVCLDVDHPEIMDFINWKSKEEDKVRALG-KMGYDTDID--GEAYETVSG 306 
225873206  239 TASGPLSFMRGFDAFAGVIKSGGKTRRAAKMVILNVDHPDIVDFIECKMKEEAKAWALM-REGYDGSSGpdSEAYSSIFF 317 
86158038   209 EASGPVSFMRGFDAFAGVIKSGGKTRRAAKMVILDVDHPDVVEFVNCKADEEKKAWALI-EAGYDGGFNvrGGAYDSVFF 287 
262198687  217 TASGPVSFMRGFDAFAGAIKSGGKTRRAAKMVILDAEHPDIVDFVECKAKEEQKAWALI-DAGYDGGFNepGGAYDSVNY 295 
32477697   262 TPSGPLSFMRVYDSIAGVVKSGGKTRRAAKMQSLKVWHPDILEFIECKWAEEKKAHALI-REGYDSNFN--GEAYASVCF 338 
116620784  237 RASGPLSFMKGFDAFAGVIKSGGKTRRAAKMVILNVDHPDVDKFIWCKAKEEKKAYTLV-EAGYDSSLD--GEAYSSIFF 313 
28210310   316 QNSNNSIRFSDFFMEKVKNldsmpDDTIELEGRVD-SSVNQ--KVKVKDLWDSFAKSTWMCADPAPQFSDTFNAWHTCPa 392 
296123412  333 QNANLSVRLSDEFMRAYEE-----NKKWVTHWVTDaTKPGP--AYEARYVMRQMAEGAWHCGDPGVQFDTIINRWHTCP- 404 
283778372  321 QNANLSVRLTDEFMQAHEK-----NEKWATHWITDaSKEGP--VYEARWLLNRMAECAWQCGDPGVQYDTTINKWHTCP- 392 
15894334   307 QNANNSVMLSDEFMKKVCNlknnpDETIELKGRVD-SSVNK--VEKISNLWEAFNKSSWRCADPSPLFSDTLNAWHTCPg 383 
300853872  307 QNSNNSVRFSDEFMNKVSKleqnpDDTIELIGRTD-PKLNR--IEKIKNIWDAFNNSAWKCADPAPQFSTTFNAWHTCPa 383 
225873206  318 QNANNSVRVNDEFMRAVEK-----DGEFTTRTVKD-GAAVK--TYKAREIMHKIAEATWQCGDPGMQYDSTINRWHTSK- 388 
86158038   288 QNANHSVRVTDAFMRAVLE-----DREWKLTARTD-GEALE--TIRARDLMRQITEAAWLCGDPGMQFDTTINAWHPCP- 358 
262198687  296 QNANHSVRVSDSFMQAVVD-----DSSWTTHAVLD-GRDIH--TMPARELMRKIADAAHLCGDPGMQFDSTINDWNPCI- 366 
32477697   339 QNANLSVRLTDDYMEAVRK-----NENFQTRWITD-KPTTEppSYVAKELLNKMAECAWHCGDPGVQYDTTINKWHTCP- 411 
116620784  314 QNANNSVRASDEFMDAAMR-----DDDWWTKGVFT-GQPVK--RYKAKDLMRQIAEATHQCGDPGMQFDTTVNRWHPCK- 384 
28210310   393 gedgnvnaKHNKINSTNPCGEYAFLDNSSCNLASINIYKFYDGKEkNIDLESYLHVVGLVQLALEASIYWGQFPTKDIAQ 472 
296123412  405 --------NDGRINASNPCSEYMFLDDTACNLASLNLRKFQREDG-RFDVERYRSAINIFLTAQEILVDHASYPTPQIAA 475 
283778372  393 --------NSGRINASNPCSEYMFLDDTACNLSSINLMKFREADG-SFNVDRFKTACRLFFIAQEILVDHASYPTEQIAR 463 
15894334   384 gedgnfnaDYNKINSTNPCGEYAFLDDTSCNLASINLYKFYDTENkTFDLEGYKHVIGLVQLLLEASIHWGQFPTEDVAR 463 
300853872  384 gedgklnaPYNRINSTNPCGEYAFLDDTSCNLASINIYKFYNITNnTFDIEGYLHIIDLVQLILESSIHWGQFPTEDIAR 463 
225873206  389 --------NSGRINASNPCSEYMFLDNSACNLASFNLLKFMTPAG-TFDIRAYRHAIDVLITAMEILVDNSGYPTENIAR 459 
86158038   359 --------NTDRINASNPCSEYMFLDDSACNLASLNLMHFRSIEG-GFDVESFKRAVDLTILAQEILVSNAKYPTPAIGK 429 
262198687  367 --------GTARINASNPCSEYMFLDDSACNLASLNLRRFQSEDG-NFDVEAYKHAIEITTLAMEIIVDNASYPTPKIGE 437 
32477697   412 --------NSGAINASNPCSEYMFLDDTACNLASINLMKFVQQDG-SFDHERFRAACRTFFIAQEILVDHASYPTEPIAR 482 
116620784  385 --------NTARINASNPCSEYMFLDDSACNLSSLNLMKYVGPDG-QFDVEAFRHAVDTMILAQEIIVDNASYPTEKIGQ 455 
28210310   473 KTYMFRATGLGITNLASLLMVLGYPYNSTEARNISSALVGLLTGYSYYISSLM-AKEIGTFE-----------------K 534 
296123412  476 NSHKYRPLGLGYANLGSLLMSMGIPYDSAAGRGICGALTSLLTGQAYLTSSRI-AAFAGPFE-----------------G 537 
283778372  464 NSHAFRPLGLGYSNLGSLIMSNGLPYDSEAAYGLCGSVTALLHGAANLASAEM-AAVVGPFE-----------------G 525 
15894334   464 KTHMFRTTGLGISNLAALLMVMGYPYDSEEGRAISSSLIGVLTGYSYYISSLM-AKEVGAFE-----------------K 525 
300853872  464 KTYLFRTTGLGISNIASLFMVMGYPYDSDEARTLAASLVGILTGESYYVSSLM-AKEIGPFK-----------------K 525 
225873206  460 NSHDYRPLGLGYANLGALLMALGLPYDSDAGRDFAATLTAIMCGEAYLQSSRI-AEKCPPLAsatpltasvernggacpG 538 
86158038   430 NSEEYRPLGLGYANLGALLMASGLPYDSDGGRACAAAITALMTGEAYAMSARI-ADRMGPFA-----------------G 491 
262198687  438 NSHRFRPLGLGYANLGALLMSRGLPYDSEPGRAYAAALTAILCGQAYRTSARIaADATGPFA-----------------G 500 
32477697   483 NSHKFRPLGLGYSNLGSVIMTAGLPYDSDAARGMCGSLTALLHGEANRTSAEL-ASVVGTFD-----------------G 544 
116620784  456 NSHDFRPLGLGFANLGALLMSMGVPYDSDHGRDFAGAITAVMCGQAYLTSSRV-AEAVGPFE-----------------G 517 
28210310   535 FSINKPHMLKVIRNHAKVA------------GSINGlYEdlnynpvkVDHNLLENIgfsdlsnllKKSWLKALNSGEEHG 602 
296123412  538 YRNNADPMLRVMRMHRDAV------------DRIDSs----------CPEELRKAA---------EEVWDDVVDSGRRFG 586 
283778372  526 YEANREPFLRVMQMHRDAV------------EDINPaGP----------ADLQEAA---------RATWDQVLALGRRTG 574 
15894334   526 YNINKEHMLKVLRNSARAA------------GSIDTpFEkigykplvVNHSILEKEdlryisselKNSWNSALESGEKYG 593 
300853872  526 FEINKPYMMRVLRNHARAAsvdieslqailgNNFSNeFEdlnyvplkVKHSVLKKEglsyigktlKDCWINALKSGIKFG 605 
225873206  539 FYVNREPFLDVIRMHRAEV------------NKIGKsKTssepfkvpELDALITAS---------KECWDQALAHGEKYG 597 
86158038   492 YEKNRDPFLGVIRKHAQHV------------DLVDP-TL--------VEPGLLSAA---------RDAWGDALRQGMESG 541 
262198687  501 YDENREPFLRVMNKHRKAV------------ADIDA-AL--------VPYDLMEAA---------RGAWNDVVELGEKHG 550 
32477697   545 YVENEAPMLRVMQMHRDAC------------DQINDdGP----------AELKEAA---------RELWDGVLEIGEKYG 593 
116620784  518 YAANEDPFLEVIRMHRDSV------------KRING-NH--------LPTALMSGA---------QECWDYAYESGRRSG 567 
28210310   603 YRNAQVSVIAPTGTISFAMDCGATSIEPFFSHVVYKKLSGGGMMTVTNPVIELSLKNLGYSKEQIKDILQYVLEkevvqt 682 
296123412  587 FRNSQATVLAPTGTIAFMMDCDTTGIEPDIALVKYKQLAGGGLMKIVNRTVPLALKTLGYDSPEVERIVKAIEE------ 660 
283778372  575 FRNAQATVLAPTGTISFMMDCDTTGIEPDIALVKYKQLAGGGMLKIVNGTVPMALGKLGYDDPQIKGILKYVNE------ 648 
15894334   594 FRNAQVSVMAPTGTISFAMDCASTSVEPFFSHVIYKKLSGGGYMTLTNPLIQESLKHLGYSENEIEDITNYILRkkkvkt 673 
300853872  606 YRNAQVSVIAPTGTISFAMDCGATSIEPFFSHIVYKKLSGGGFMTIINPVITIALKNLGYTSEQIEDILSYVLEkenvse 685 
225873206  598 YRNSQVTVLAPTGTIGFMMDCDTTGIEPDLALVKYKKLVGGGMIKIVNNTVPAALFKLGYKNEDVDAIVSYIDA------ 671 
86158038   542 YRNGQVTVLAPTGTIGFMMDCDTTGIEPDIALVKYKKLVGGGMLKIVNNTVPLALQKLGYSSEEITSVLQFIDE------ 615 
262198687  551 FRNAQTTVLAPTGTIAFLMDCDTTGVEPDIALVKYKRLVGGGMLKMVNQTVPEALRRLGYSEQQLEGIINHIDT------ 624 
32477697   594 FRNAQATVLAPTGTISFMMDCDTTGIEPDIALVKYKQLAGGGMLKIVNQTVKLGLKTLGYDADTIDEILKYVDA------ 667 
116620784  568 YRNAQVTVIAPTGTIGFMMDCDTTGIEPDLALIKYKKLVGGGVIKIVNNTVPAALVKLGYTPEQAEKIVTHIDS------ 641 
28210310   683 kegfkyekvlDGKIEGAPHLKKEHYAIFDTANKCGSGKRYIEPMGHVKMVAALTPLISGAISKTVNLPNNATIEDFKKVI 762 
296123412  661 ----------HDTIEAATDLSPDHLAVFDCAFKPASGTRSIQWRAHIKMMAAAQPFLSGAISKTVNMPADSTVEDIEKAY 730 
283778372  649 ----------NDTIEGAPELADEHLAVFDCAFKPANGVRSINWRAHIRMMAAAQPFLSGAISKTVNMPTDVTPADIGDAY 718 
15894334   674 ddgteyetilDGKIEGAPHLKKEHLAIFDTANKCGSGNRFISPMGHILMVASIVPLISGSVSKTVNLPKDASVEDFKNVI 753 
300853872  686 nd-ytyekilDGKIEGAPHLKDEHLSIFDTSNKCGSGERYIDPMGHVKMVASLTPLISGSVSKTVNLPKTASVQDFKDVV 764 
225873206  672 ----------TGTIEGAPGIKPEHLAVFDCSFKPAKGTRSIHYLGHIKMMAATQPFLSGAISKTVNMPHDSNIDDIAEAY 741 
86158038   616 ----------VETIEGAPGLRPEHAPVFDCAFKARNGTRSIHYMGHIRMMGAVQPFLSGAISKTVNMPTSATPQDIENAY 685 
262198687  625 ----------QESIEGTSVLKEEHLPVFDCAFRSPSGTRSIHYMGHIRMMSAVQPFLSGAISKTVNLPSDCTVGDIEDAY 694 
32477697   668 ----------NDTIEGAPGLQDEHLAVFDCAFKPANGVRSIGWRAHITMMAAAQPFLSGAISKTVNMPTDVTPQDIADAY 737 
116620784  642 ----------TGTIEGAPDLKPEHLAVFDCSFRPQNGSRSIHYMGHVRMMAAVQPFISGAISKTINMPEECTVEEIMSAY 711 
28210310   763 LNSWELGVKGIALYRDGCKASQPLNVSLSSEKDFELEDLDYKSLLEKSKELQrklq------------------------ 818 
296123412  731 AEGWRLGLKALAVYRDGSKQSQPLNVKKGGDGNKEVAP------------------------------------------ 768 
283778372  719 TWGWQLGLKALAIYRDGSKQSQPLNTKNDASKEKEAAAPAEKAV------------------------------------ 762 
15894334   754 INSWKLGVKGITLYRDSSKESQPLNTSLDEASKTAPEDMTYAQLLNMVKNINtt-------------------------- 807 
300853872  765 LTSWKLGVKGITLYRDSSKAAQPLNTTLSDSNDINIEDFTYNQLLSKVKELQkg-------------------------- 818 
225873206  742 LESWRQGLKAVAIYRDGSKGAQPLNVSDGKGAKEIKGATADATLLAAADRVLtalatgkaaaesdvktlatkvsekievs 821 
86158038   686 LESWKLGLKAVAIYRDGCKRSQPLNTGKEQEERKDVAE------------------------------------------ 723 
262198687  695 LQAWKLGLKAIAVYRDGCKRTQPLSTSKQQATSNGAIAKTLSESDVLELLAPderamiedlr------------------ 756 
32477697   738 FWGWELGLKAIAIYRDGSKQSQPLNTKSDEQKATDAAEAAKVETVEKIV------------------------------- 786 
116620784  712 TESWKLGLKAVAIYRDNSKRVQPLSSGSGKGEKKNAGAVAIAAAAAAAPIERv--------------------------- 764 
28210310   819 ------------------------------egvNYSSREKAIGIRNGTTHPAQINDVKIYTTINRRQNGEISEIYITTDR 868 
296123412  769 ---------------------------------GQPVRRRLPTTRHSLTHKFSVGGHEGYITVGLFEDATPGELFISMAK 815 
283778372  763 ---------------------------------AKPRRERLPDTRQSVTHKFNVGGHEGYINVGLYPDGRPGELFITMAK 809 
15894334   808 --------------------------------qKYIKRERAVGIRNGKTHPAQIGDIKIYTTVNRRDNGEISEVYITTDR 855 
300853872  819 --------------------------------iKYSKRDKIIGIRKGTTHPAQIDDVKIYTTVNRNSNDEISEIYITTDR 866 
225873206  822 agqvataasafaatltalaaggvrmedqdlnapPRAVRHRLPEERASLTHKFALAGHEGYITVGLYPNGQPGEIFIKMAK 901 
86158038   724 ---------------------------------PRLARRRLPDERRSITHKFSIGGHEGYMTVGMYDDGTPGEVFITMAK 770 
262198687  757 ------------------------vrkagpagpPAAVRYKLPPERQSFTHKFSVGGHEGYITVGLYEDGQPGEIFVRMAK 812 
32477697   787 ---------------------------------YKPRRERLPDTRQSLTHKFSIAGHEGYLCVGLYPDGRPGEMFITMAK 833 
116620784  765 --------------------------------vYRPVRRKLPDERRSITHKFSIGGHEGYITVGMYEDGAPGEIFITMAK 812 
28210310   869 EGTIIMGLLNSLSKALSIMLQYHVPPQDISKMLRGQKYEPYGFVQKhPYIKYVSSISDLISKIIDIEVGDF--------- 939 
296123412  816 EGSTIGGLMDVIGTETSMCLQYGVPLEVLVEKFSHSRFEPSGWTQN-PDIPNAKSVVDYIFRWMAIQFMPGfreanvprr 894 
283778372  810 EGSTIGGLMDAFGTAVSMSLQYGVPLEVLVNKFSHTRFEPMGHTTN-PDIRIAKSVVDYIFRWLGINFLDGyre------ 882 
15894334   856 EGTLIMGLLNSLSKSISVMLQYHVPPKDISEMLRGQKYEPYGFVQKhPYIKYVTSISDLISKIIDIELNDF--------- 926 
300853872  867 EGTIIMGLLNSLSKAISVMLQYHVPPQDISRMLRGQKYEPYGFVQKhPYIKYVSSISDLISKVIDIELGDF--------- 937 
225873206  902 EGSTVSGLMDSFATAISLALQHGVPLKVLCEKFAHSRFEPSGWTGN-EQIGYAKSIMDYIFRWLQIRFLSGqql------ 974 
86158038   771 EGSVVSGLMDSFATGISMALQYGVPLKVLCDKFSHTRYEPSGFTGN-PDIPIAKSVTDYIFRWLALKFLPSeeg------ 843 
262198687  813 EGSVIAGLMDSFATAASLALQHGVPLAVLCDKFKGTRFEPSGFTGN-PDIPIATSIMDYLFRWVHLRFLDGevhpa---- 887 
32477697   834 EGSTIGGIMDSFGTALSIAMQYGVPLEVIVNKFSHTRFEPMGHTSN-KDIRIAKSVVDYIARWLGITFMSGndys----p 908 
116620784  813 EGSTISGLMDAFATAVSFNLQYGVPIKFLVDKFAHVRFEPSGWTGN-QQIPYAKSIMDYIFRWLGNKFLGA--------- 882 
28210310   940 ---SRCQVKPENydlntnarnvfntnd-----------------------------------iikdqfatnspnyiSNQS 981 
296123412  895 aeaASAEEGESAeshrvagaapatpagkahglngslkpeikgsdklpaslekrihaplptsgtngshttnghtsngHANH 974 
283778372  883 aslGYAATATTSddqrspaatkaggptaagstataslpaapqpa-gkeattsstpaaaatsaitrsaaaaveaarpTGKP 961 
15894334       --------------------------------------------------------------------------------     
300853872  938 ----------SRcqvkp-------------------------------------------------------enydKDSL 952 
225873206  975 slfAGLAAPASGegieals---------------------------------------------------taalspEQHT 1003
86158038   844 svvSPPPLMTPG----------------------------------------------------------------QAPA 859 
262198687  888 -----------------------------------------------------------------------aqgrgVGQL 896 
32477697   909 saeGAAKTGGNGpdlttapagatannnspvmaelrad---------------agaavalveratllaslqngvsngSATN 973 
116620784  883 ----------------------------------------------------------------------------EYAT 886 
28210310   982 KDSNNNDNSASDNDLASNNTyktvdg---------------kavagERLYCSTCPTCsSTRMVRNGTCLVCLDCGSTTGC 1046
296123412  975 GKTNGSTHAELHVLDQSRSQqf----------------------srFQTDAPACSNC-GSITVRNGACYLCHNCGTSLGC 1031
283778372  962 AAAKVEVASLSSKNGVDTDLleragvamkvdnngapigsrseqfakFQSDAPSCGYC-GNITVRNGNCYLCHNCGNSMGC 1040
15894334   927 -TRCQVKPEGIKDITPQKEIkekl-------------------sqgERLYDITCPNCsSTRMVRNGTCYVCLDCGTTTGC 986 
300853872  953 VLGNSSPELNTIKTNGNETKikk--------------------idgEKVYGTVCPTCsSTRMVRNGTCMVCLDCGSTTGC 1012
225873206 1004 PTRGMGATGAPQGGLLSELHataeagdlkmedrgvfhaadamkdlyDMGDAPSCHTC-GAIMVRNGSCYRCMSCGSTSGC 1082
86158038   860 RHGSSEQTVVVKSLPATNGAmngsng--------------vngahvTDTDAPPCPTC-GSITVRNGACYKCVNCGSTTGC 924 
262198687  897 DLPSVPLTPGERGAAQAGHIvieqage-------------mpstwvRESDAPPCHEC-GTLMVRNGACYKCANCGATSGC 962 
32477697   974 GHSNGQSAGGSSDGAVAERAvdglggq-------------adqfsrFQTDAPSCDNC-GSITVRNGNCYLCHNCGNSMGC 1039
116620784  887 TEAGETMTLRPTEADPQQSLpf----------------------npMTADAPLCAEC-GSIMTRNGSCYKCGNCGGTSGC 943 
28210310  1047 S 1047
296123412 1032 S 1032
283778372 1041 S 1041
15894334   987 S 987 
300853872 1013 S 1013
225873206 1083 S 1083
86158038   925 S 925 
262198687  963 S 963 
32477697  1040 S 1040
116620784  944 S 944 
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