Conserved Protein Domain Family
Trep_Strep

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TIGR02185: Trep_Strep 
putative ECF transporter S component, Trep_Strep family
This family consists of strongly hydrophobic proteins about 190 amino acids in length with a strongly basic motif near the C-terminus. If is found in rather few species, but in paralogous families of 12 members in the oral pathogenic spirochaete Treponema denticola and 2 in Streptococcus pneumoniae R6. [Transport and binding proteins, Unknown substrate]
Statistics
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PSSM-Id: 274019
Aligned: 11 rows
Threshold Bit Score: 125.471
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAS12679   7 FKTKDFVFIGIMTVVYIAVFMVIGFVTAAINPF-LHAFSPAITGLVVGTIYLFLAIKVPKFGVFTISQLLLIMIVLILGM 85  Treponema denticola...
AAS11398   8 WKISHFVLIGLMAAIYAAVIYGVGMLTAVTIPV-MHVFAPGMTGFLMGPIVLFVVKTVRRFGVLTLLAGLGVALFTLTGM 86  Treponema denticola...
AAS10779   9 LQTKDFISIGVFSLVYFAAAFIIGGVAQMTPVT--FPFMPMIVALFAGSIFMLYTAKIPKRGAISILGILAGLLLFITGM 86  Treponema denticola...
AAK34523   4 LTIKDIMITGAFAALYFICVGLGTFINIFFDRSgNMLYAPAFAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGH 83  Streptococcus pyoge...
AAS13141   7 LKGRDLINIGIYSAIYFVILFAVAMLGMIPIFL---PLLSVFVPIIGGIPFMLFLTKVKKPGMIFIMAMIMGILMLLTGM 83  Treponema denticola...
AAS12113   7 FQIKDLIITALMVLCSQILYRILSFLFMSPYTM---LLTMPIWAIIGAIAYFLVPAKTKNPWMILLFCILTSIIGFYP-- 81  Treponema denticola...
AAM75303   1 MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFg-HSISPGIFGLLSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGG 79  Enterococcus faecalis
AAS10753   7 WTIKDVITTVLLSALLVVMQFIVNMVCMANHFVs-MTLSVGFSVFICAPVYFLMVQRVGKRGVSFIYMTLLGIIFLIMGN 85  Treponema denticola...
AAS10738   8 LNARDFIFIGIFAAVALLIFFITGALAALTLFG--TIANIPITLFFVSIAFMLAVSKVRKTGVFFIMGIIIVLPGFMAAN 85  Treponema denticola...
AAS11389   5 IGLKDIVLITLLTAIMIGIQTVVLMPFITNLKF-VIWFVGGIDGVLCGIIYCLMIAKAPKLGTAFIFSFIFAVYYFFVNS 83  Treponema denticola...
AAS12122   1 MKLKDIVRIAVLTVIGFAIGMAISMLTGTLGAIa-LYASAGFAAFAVGPVFVITAKKVKHRWTAFLFWLIYGLLYTLMG- 78  Treponema denticola...
AAS12679  86 gYLPWLIGMFIGAL--LGDIAANTSKYKnKYTIAIASGFICLGSASGGVIPVLFFVEHyKKFCFERMQMn-EAQVEQSIA 162 Treponema denticola...
AAS11398  87 gSINCLIFVVIAGL--IADVIIAKTGFK-TLSVGIGHGLTQAAYFTGGVFPFLFFLER-ELAKWQEMGMs-REEILEYVK 161 Treponema denticola...
AAS10779  87 -FWMMSVFFIIFGF--IADGIASFGEFK-SFKKNLTAYCIFALAPMGAYIPMAVMPAQfDAFMRKKGDF---SSFAEVIN 159 Treponema denticola...
AAK34523  84 -FFAAMFPSIIFGL--IADIIASLGKYK-SRFFNDLSYMVFAFVNSGPILLMWLLKDAyVESLLARGKS---MTYVNRIM 156 Streptococcus pyoge...
AAS13141  84 gPWPLLICAIAGG---LAELCFKSGEYK-NAKKAVLSYGLFSVWIFGNYLPLFTDYEG---YFAQRADYg-QAYIDAVSK 155 Treponema denticola...
AAS12113  82 ---PYIISCIIGGV--LAMLIARIKGIEnYKGLTIGYILFCVLASFGGMYVPFLFYAEqTLNAYKEMFG--AEYLETLTK 154 Treponema denticola...
AAM75303  80 aYLPWFISSISMAI--LADIILYVFGYDrAIPQVVSWVLMQLGSAAGQWIPIWFFTDRfRQDWIDRGQS--AATMDAMIH 155 Enterococcus faecalis
AAS10753  86 -WYLLPYYIIIGLI--CEAVLWKHGAYQnPRRLMAAWTVSSLLFNGTNLLPIWFFWDAyYAFAVSSGMS--QEYIDSYVR 160 Treponema denticola...
AAS10738  86 g--IGVGLSIIGWF--IAETLASTMKYKdKKAIILSYVLGSTLQTALFTLPMYLSHGEyFVQRKEILHLt-DEALQQYLQ 160 Treponema denticola...
AAS11389  84 ---MIIISAMIAGAglVMELILWNNGYKnKIKATIAYVLFGLTIMLAPNVLIFLQKDAmIAGLQANGLT--QEYIDSIFA 158 Treponema denticola...
AAS12122  79 -YWIMIPICLVSAV--LAEIIIG--DYSsNVKVSIAFSAAMFIVAMHPIIFVKVLGAEgITKFAPSISSeqAQWMIQFYT 153 Treponema denticola...
AAS12679 163 AS-AGYLGVIILIATFVLG-----FAGVLIGSKILGKHFKN 197 Treponema denticola ATCC 35405
AAS11398 162 YF-TGTFAVIGIVSAIVFG-----IAGVYIGKLILKRHFKD 196 Treponema denticola ATCC 35405
AAS10779 160 ----AIGANRWVVPAMIAGtvvcaIIGGMIGKKLLKKHFEK 196 Treponema denticola ATCC 35405
AAK34523 157 YD-FSLGHVIWFVGIVLAGa----LLGSVFAHYLLKKHFIK 192 Streptococcus pyogenes M1 GAS
AAS13141 156 LM-PLWMAPVLLAVCLVCG-----ILGGLLGKALLKKHFEK 190 Treponema denticola ATCC 35405
AAS12113 155 LV-SPTITVIMLIITALCG-----CIGALISKKLLKKHFEK 189 Treponema denticola ATCC 35405
AAM75303 156 YA-VGIWGIISVLVVASLS-----MIGVLIGRKVLKKYKK- 189 Enterococcus faecalis
AAS10753 161 YFtVPYWIIFIVAFTTVCG-----FAGSLIASRLIKKHFEK 196 Treponema denticola ATCC 35405
AAS10738 161 VVgSWQMYGSMIALTVITS-----FAGAWISMRILKKHFEK 196 Treponema denticola ATCC 35405
AAS11389 159 VY-SAENIGIGMLLTAIGS-----IAGTQIGYRLLNRYFIS 193 Treponema denticola ATCC 35405
AAS12122 154 GKaIAIAVACNIVLESLAG-----LFGTYINKKFFEKSSKK 189 Treponema denticola ATCC 35405
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