Conserved Protein Domain Family
LptD

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COG1452: LptD 
LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA) [Cell wall/membrane/envelope biogenesis]
Statistics
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PSSM-Id: 441061
Aligned: 473 rows
Threshold Bit Score: 158.612
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_064536588   97 SKDvKDvgryK-IIiESTDNLEnftYEiTGDETIIFKGRVSLVI-----EDikdnkkHNIKGDKIIFNKKTKKLFSSGNV 170 
WP_081434329   94 DEP--Q----S-WR-LLADKTA---AS-HDNQYLEAFGNVVLDR-----GN------DYIRADYARYYQSTKWVFLKGNV 150 
WP_015751527   36 TSP--E----TpWE-VEADSVS---AD-QDIQLLEAWGDVTLHK-----GE------NYLKADYVRYYWSTRWVYLRGNV 93  
WP_013164430   39 PAA--P----E-WE-LSADSLS---HQ-LDPSRVTAEGNVVLSRpqehgEP------LVIRADQMVYDPESGTVEARGRV 100 
WP_013375762   26 P-T-GE----T-VE-VTADLVV---SE-PERQLLIARGHTQLRT-----GQ------TVLRADEVTYDQGAQTVSATGGV 82  
WP_013513763   48 PDL--D----E-WT-FSADRVS---GD-HTSEYVEAFGNCTLAL-----GD------NQLRADFARYYQATGWVFLKGNV 104 
YP_010175      31 AET--V----T-WH-LTADNLS---TL-NESKILEATGQVALRR-----GN------EFFKADYARYYSTTNWVYLKGNV 87  
WP_015353660   47 QSQ--T----K-WN-LEADTLT---TL-SNNTIIEAKGNIILTK-----GQ------DVFKADFARYYQKTGWLFLKGHV 103 
WP_095975860   26 P-T-GQ----A-VE-LSADHVL---YD-PEQRVLTAHGHTRLSS-----GT------ALLRADEVVYDQANETAVAKGNV 82  
WP_095986079   26 P-T-GE----T-AQ-LAADDVS---YA-QEQRVLTARGHAVLSS-----GP------VVLRADEISYDQAHETAVARGNV 82  
WP_064536588  171 DYKfdlsASEKLyFYGSELFIDFDSQNfILKNGIVQkkmhRnlvdHi---------------------VSFGGKVLRRLD 229 
WP_081434329  151 EAR----FQGDF-LKAEEAEFDLNTNTgWLKNGQIFm--qDp---H----------------------MYFEGAVLKKTG 198 
WP_015751527   94 QGN----WGGDH-LQAEEAEFDLQSKVgWLNNGTIFv--qDp---H----------------------MYFQGRVLRKTG 141 
WP_013164430  101 RLE----STTEE-VEAEGVVLHLESQTgTLEQATIHl--vEs---G----------------------VYVRGAHIEKTG 148 
WP_013375762   83 MFV----SGLFA-AVADAVVVDLKSNEaTAE-GGLFm--qKr---NvtpealaaaetpqqlremgdtpMLFRGTRIRRTD 151 
WP_013513763  105 RAQ----WGGDF-LQADEGEFDLNTMTgWLKNGRLFm--aKp---H----------------------VYVEAERVAKTV 152 
YP_010175      88 EVF----TGTET-IRAEEAEFDLRSRTgWMQKGEIFm--eGp---H----------------------IYFTGERVTKKW 135 
WP_015353660  104 TVK----MDENE-INADEAEFNLNTKTgWLNNGNIFi--sSs---H----------------------VYFSGARITKHY 151 
WP_095975860   83 MLV----SGQMA-AVADEVTVDLKSSEaSAK-GGLFm--qKr---GvtpeqlraaqtpqelrdlgetpVLLSGSRIKRIG 151 
WP_095986079   83 MLV----NGLMA-AVADELSVDLESSEaVVQ-GGLFm--eKr---GvtpqqllqaqtpqelrdlgetpVLMSGRRIKRTG 151 
WP_064536588  230 NDANILEKAFITSS---KIPEPYYSIRASKIWILPSGDFGILNAVFYIGRVPIFYIPFFFKP---G-DSLFFNPSLGYSS 302 
WP_081434329  199 QDTYEFREATITVC---DGDRPAWSIKTSRGDITVDGYAHLWTPRFQILDQPVFAAPYAVIPvktKrQSGFLLPEIGTSD 275 
WP_015751527  142 TNTYAFEDATVTAC---DGQVPAWSLRSASGEITVNGYARLWHPRLQIKNRPLLYAPYLTIPvktKrQSGFLWPDLTVSS 218 
WP_013164430  149 PESYYLEDAWYSACrpeEDCRPAWSLKSSKVYLTVDGLAHFVHPRLQVKEVPVLYSPYLMAPanvHrQSGFLAPELSTSR 228 
WP_013375762  152 ANTFMVEDLVFNPCvc-gpGDPDWRMEARDASIITGERAILTWPVVYIASVPVLALPWLYLPl-sDrRTGLLMPRLTTSS 229 
WP_013513763  153 GDTYTFKNAKVTAC---DGEKPAWSVTSEEGEVQIDGRVKLYRSAFRIKDVPVFYWPYMSLPgrkArQSGFLPPSISSSD 229 
YP_010175     136 GDYYTFEKAKVTSC---PPDGEAWSMNAEQAVVEIDGYAQLFGATFDVADTSLAYSPYMILPakrTrQTGLLMPEYGMST 212 
WP_015353660  152 GDYYTFNNVKVTTC---DGPHPAWSISAKEAIVEVDGYAQLYDSTFKIKNIDVMYSPIFTIPakqTrQSGFLNPNYGISQ 228 
WP_095975860  152 DDSFQVEGIALAPClc-edGPPSWRVEASQGSVVLGERASLTLPVVYVHDVPVFALPWLYLPl-aErRSGLLIPKPTTSS 229 
WP_095986079  152 DNTYQVEGIALAPClc-geSVPSWRVEASSARVEMGRYASLTLPVVFVRSVPVLAVPWLYLPl-sErQSGLLFPRPTSSA 229 
WP_064536588  303 RKGLTLFNTVYLLGKKSVdidkvsflDFDFhsiynadkksyirngyltyffaedvvsrvnkdyvklIFDIYSNLG-F--- 378 
WP_081434329  276 RLGITYDQPYYQVIDEEQ--------DVTL------------------------------------YSHLMSNKG-L--- 307 
WP_015751527  219 EHGAGFNLPYYWAINEEQ--------DATF------------------------------------YLNPMDKTG-V--- 250 
WP_013164430  229 RRGDGLALPYFVNLSPSA--------DLTL------------------------------------YPKYMDRRG-L--- 260 
WP_013375762  230 IAGFGIEQPIFITLGRSY--------DLTV------------------------------------SPGYYTGASrEthd 265 
WP_013513763  230 KLGMQVNLPYYWVISDEA--------DATF------------------------------------YQNFMSRRG-Y--- 261 
YP_010175     213 RRGVYYNQPFYWAVDDRR--------DVTI------------------------------------NEYWMEKRG-F--- 244 
WP_015353660  229 RRGIYYTQPYFLNIDQSS--------DLTF------------------------------------YAGLMTKIG-P--- 260 
WP_095975860  230 LNGFSLEQPIFLTLGRSY--------DLTF------------------------------------SPGFYLGAS-Eqev 264 
WP_095986079  230 ISGFGLELPVFITLGRSY--------DLTL------------------------------------SPGFYLGGG-Evdv 264 
WP_064536588  379 ----------------------YSGIdfdvgstldFFktfkgsfgigltRTLYkh-lSGVYrpfknNS--INYS--Lf-- 429 
WP_081434329  308 ----------------------MLGA---------EY------------RMVPdihsKGIW-----KLdyLYDQqieges 339 
WP_015751527  251 ----------------------RAGV---------EY------------RHTPnlssQGMW-----LAdwLYDRstAtaa 282 
WP_013164430  261 ----------------------QSGV---------EF------------RYAAapgsLGMF-----QFtyLKDKhqDtad 292 
WP_013375762  266 lgggtlre----epryvgirgpRLLT---------EF------------RYVPseqtRGRW-----TLgfIYDLqpIrdp 315 
WP_013513763  262 ----------------------MQGF---------EF------------RHSEdsatKGVW-----QVdaLKDNirAvse 293 
YP_010175     245 ----------------------MHGV---------EY------------RSREasdtAMWM-----RFdwLDDLttVknd 276 
WP_015353660  261 ----------------------LGTV---------RY------------RSHKftnqKTWF-----AAsgIHDKnnIvtp 292 
WP_095975860  265 nrtlagetitreeprttgirgpRLLT---------EF------------RYMPsvgtEGRA-----TLglLYDLqpVrnp 318 
WP_095986079  265 trnignqditrkepqsygirgpRLLT---------EF------------RYAPavgtEGRV-----SLglLYDLrpVrnp 318 
WP_064536588  430 -------------------SfDNinkgdifgfevpfrylFTYKSEFSiSD--ALFSVVFEHYSDp-YVIidfK------- 480 
WP_081434329  340 ly---------sdnvgmsrE-NRnr------------wwGRGKFDGYvGEpdWNLKFDLDMVSDqdYLRe-fSrgysgfn 396 
WP_015751527  283 sdtey-------endgllrP-NHnr------------ywLRGKYDGKtFGnlFDLKVDVDYLSDqdYLNe-fDqgplgfe 341 
WP_013164430  293 dpyr---------ndgwlrD-SSqr------------ywLRGKADHDfGDd-LLLRLDLDLVSDqdYIMe-fDsglmgya 348 
WP_013375762  316 rtgafyrqgneplgeaitqA-RGlr------------geTSWQHTQEmGHg-FSNRVDAAFVSDgyFTRd-lTadvv--- 377 
WP_013513763  294 adewkd-----yrgdgmarP-NRsr------------wwVRSKYDGWlGStdLKVKLDLDVVSDqnYLRd-fQkgpngyd 354 
YP_010175     277 addpi-------akdglvrT-NSer------------fwLRGMTEGRlGDpdWRYKLDLDYVSDqnFLRe-fNsgmsgfg 335 
WP_015353660  293 gkdpv------ypssqlvrN-NHqr------------ywVRGMADGFiGNstWCYISNLDYVSDqdYLRe-fDqgitgfs 352 
WP_095975860  319 vtggfyl---deageliraR-RGir------------geASLQHRQDlGGg-WYDRIDAFAVSDgfYTRd-vTadiv--- 377 
WP_095986079  319 vtagffl---tdtgdllrtP-RGlr------------geASLQHRQDlGGg-WYDRIEAFAISDgfYTRd-lTadiv--- 377 
WP_064536588  481 -------------------DRLESATFFSvlspqKELsetEkmiKtfdWNLSSFynrtfdnnflvDYRlnNLgftfk--- 538 
WP_081434329  397 ksrrdflqyfgrdiedsdsNLRINRALLS-----RNW---G---Dl-gFQGLLE-----------YTQ--NLeygsnnn- 450 
WP_015751527  342 rsrqefldvfgrtiededdITRENRLYLS-----RNW---Q---Ds-gLRMRLE-----------YTQ--NLaftnd--- 393 
WP_013164430  349 rstsafesmfdrelqepslATRRSTLQLF-----RLR---P---Tt-lVAGELM-----------GQQ--DSrhtlnyqg 403 
WP_013375762  378 ---------------arenQYLRSTGAIS-----HRg---E---Eh-yLGLEVA-----------IRQ--DIrway---- 413 
WP_013513763  355 svsqefldtfgrdidkkdsATRTSVAYAS-----RSW---D---Rf-gATGALT-----------YVE--NLafmng--- 406 
YP_010175     336 ksrsql-felfgrdireldrNRISQGMVY-----REW---D---Ra-tVALSAR-----------YEQ--DPslghg--- 386 
WP_015353660  353 hsrsem-fqmfgrdiqeddqSRLNALLIR-----KDW---Q---Ri-gVVGNIR-----------YEQ--DPtlghg--- 403 
WP_095975860  378 ---------------arenQYLRSSGVLY-----RRs---E---Dq-wVGLEVG-----------LRQ--DIrwgy---- 413 
WP_095986079  378 ---------------araaQYLSSSGVIY-----RRg---E---Dq-wVGLEVG-----------LRQ--DIrwgy---- 413 
WP_064536588  539 --lanyD-Ni-----------------fGKTPKsIqdpTRKwfyLERiylPy---IDLNFKrdlYNNSWTSFSdskdKEi 595 
WP_081434329  451 ltnkskAdDpt----------------lQRLPE-L---NLHl--YQT---Qll-sTPLTAE---GSSQLASFW----R-- 495 
WP_015751527  394 --nrdsSlDdt----------------lQRLPQ-L---EYDi--YRT---Alg-tTPLEWS---AENELTYFW----R-- 436 
WP_013164430  404 qevdrnRrGtp----------------lQALPR-L---HASg---RS---Pmr-sQPYSLA---WSNEYVHYW----R-- 447 
WP_013375762  414 ---pffReDrvpaaadplrpvlhgprtlQKLPA-L---TLSl--PEQ---Rlg--gRWALG---MRMEFSRLS----PLt 472 
WP_013513763  407 --ngrdQdNtt----------------vQTLPE-L---NLFg--FQQ---Qip-gTPLEVS---ADAKYDYFT----R-- 449 
YP_010175     387 --nknySaDtt----------------vQRLPQ-L---DVFl--HKG---RafeeMPLEIE---AEAQTVYFH----R-- 430 
WP_015353660  404 --nhptSqSel----------------tQRIPQ-I---DMFl--YQG---KlfqpLSLEGA---IHLQSAYMY----R-- 447 
WP_095975860  414 ---sllGeHspptgavss-pipaaprtfQKLPA-I---SWVl--AER---Plf-dsRFIGG---ARVEFSRLS----PLf 472 
WP_095986079  414 ---dlfGrStvpagasgspaitaaprtfQKLPT-L---SWVl--AER---Plg-gsRLVGG---MRVEFTRLS----PLl 473 
WP_064536588  596 imvpkiknvEddv------------------------------------edGKGkSNtKKLEEQKDLTkdLylsPkpivf 639 
WP_081434329  496 ---------------------------------------------------EYG-TTgSRFDIHPIIG--L---Plhf-- 516 
WP_015751527  437 ---------------------------------------------------EYG-TTgSRLDLRPRLS--L---Ples-- 457 
WP_013164430  448 ---------------------------------------------------QEG-IGaHRLDLHPQLI--V---Plprg- 469 
WP_013375762  473 ---------GrfgdegedglfdasgarivtgpdglpqalldpaqsngrfdaSDR-EArDRLDLFPRLS--T---Sfgw-- 535 
WP_013513763  450 ---------------------------------------------------NMG-DTgHRVRLTPEVK--L---Pvkt-- 470 
YP_010175     431 ---------------------------------------------------RNG-TQgGRTEIAPRVT--L---Pmns-- 451 
WP_015353660  448 ---------------------------------------------------AKG-TKgWRTELYPKVT--L---Pidl-- 468 
WP_095975860  473 ---------Ssfgdegldgrfepga-----------dsvtdpaqgnglfdgADR-EArSRIDVNPRVS--T---Sfal-- 524 
WP_095986079  474 ---------Slfgdegldghfesdgqwvv---pggtvrepdvaqgngifdgADR-EArDRVDLLPRLS--S---Sfal-- 533 
WP_064536588  640 ndlnrpdsfyvrFGINPYFknsiffddfKFKspqEFkYDVKTylfdiKn----------------KM-NlNlhAdfyNRL 702 
WP_081434329  517 ----------eyGSIIPKA---------GVRs--TS-YFIQRfe-gdDsdv--------------dtdR-S--Tq--TRF 554 
WP_015751527  458 ----------ayGSLIPTL---------GLRq--TV-YGVERfe-stTaaq--------------etdS-A--Wm--SRT 495 
WP_013164430  470 ---------ggwTEGRATT---------GVRq--TM-YQVNEh---dEh---------------rWEyD-R--Yq--DRT 505 
WP_013375762  536 ---------gpyARVTPMV---------ALRq--DL-YGG-------E-----------------VS-G-R--Ta--QRG 564 
WP_013513763  471 ----------dyVTFIPSL---------SGDl--TS-YDLTRre-gyGnqtvvddggrtqyidtnATkS-G--Fq--ARN 522 
YP_010175     452 ----------ryGSVIASM---------GWRq--TM-YNTERak-glDgep-----------------apT--Gd--YRS 487 
WP_015353660  469 ----------kyGSVITTV---------GLRe--TY-YQTg-----iKshtspva---phvpdtkTPrQ-T--Gq--HRS 513 
WP_095975860  525 ---------gpwARLSPAL---------SLRq--DF-YLG-------E-----------------VS-G-R--Ta--QRG 553 
WP_095986079  534 ---------gsfARLSPAL---------SVRq--DF-YLG-------E-----------------VT-G-R--Ta--QRG 562 
WP_064536588  703 ItfEDVlylnTVEY-NPLDKDYnlvDkDkks----------------eySVINkinldllPFMMY---Pa-----fSRSS 757 
WP_081434329  555 L--PDF----STSAyTEFSKIF---TlNeessidkda---asatwlklkHALQ-------PRLEYdyiPy-----sEQEK 610 
WP_015751527  496 L--WDF----EATAnTEFGRVF---NlApppavsnata-gaasrwtklkHVVR-------PELSYeyqPy-----vDQSD 553 
WP_013164430  506 A--FDF----ETNLaTTLVRDF---RlApqgpsraafd--rpvtspgleHMVR-------PNLIYsyvSr-----sSESE 562 
WP_013375762  565 Y--PMV----DLQVdSELARSY---VgAest----------------yrHTLM-------PSVHLryvPgvwggvpPPGA 612 
WP_013513763  523 S--WGA----GFSAfSEMTRVF---TlSdevrpdpgla--gtskwtrlkHSVV-------PRVEYgytPti----tGQDE 580 
YP_010175     488 L--PDY----NVAAfTEVGRVW---DlEdgaldpatee-vgtrhwksvyHRVQ-------PRIEYrniAn-----vDQDR 545 
WP_015353660  514 L--FNL----QLESsTQAHRIW---RlKdkktinlhsqsigktfctalkHTIQ-------PRICYsfiPr-----eGQEK 572 
WP_095975860  554 Y--PLL----DLVVdSRLSRTF---DiAgvs----------------fqHSLE-------PSVSLryvPlvwgdlpSPGA 601 
WP_095986079  563 Y--PIL----DLVLdSRLGRTF---ElGgvs----------------llHSIE-------PSITLryvPivwgglpSPGA 610 
WP_064536588  758 Ik---------FDNkitlYSFDKkydRDsKMlngKsNtvfwkSpetfyQEVNFGLIydyrfftTSLSSilRS-------- 820 
WP_081434329  611 Yp---------------yF--DE---AD-RI---D-A-----K-----NELTYSIT-------NIFTM--KTgrwqpale 646 
WP_015751527  554 Yp---------------dF--DD---LD-RI---E-P-----R-----DELTYSLT-------QVFTG--RRdnrvpvaa 589 
WP_013164430  563 Lp---------------eL--DS---VD-RL---E-R-----K-----NWLTYELN-------NYFEV--FGyrasppps 598 
WP_013375762  613 SpglpaqrydeIDSal-pLGLd---gQD-E------G-----F-----LHAVVEVT-------QSLQL--KKeqa----- 657 
WP_013513763  581 Lp---------------yF--DR---FD-RI---Q-G-----R-----NEVTYSLT-------NVLDR--RRdtvvlspg 616 
YP_010175     546 Np---------------yY--DD---SD-RI---G-P-----R-----SELVYSVT-------NILTR--KRgtvvpard 581 
WP_015353660  573 Np---------------fY--TL---SD-RI---L-P-----Q-----NDLTYSIV-------NILTK--KNvtisvdnn 608 
WP_095975860  602 ApelpgqpydeIDSal-pITAp---gVA-R------R-----F-----LHAVVELN-------QTLRF--RKent----- 646 
WP_095986079  611 LpdspgqpydeIDSal-pSTSa---gVA-R------R-----F-----LHAVVELN-------QTLHT--RRgss----- 655 
WP_064536588  821 ----------------------------------TFeSIYASSELKFAvefpyllqevgvgiKydKKFkeeeqkSffkKT 866 
WP_081434329  647 eqg---------------------qpglqmdffeMA-RLRFEQSYSIReerrnd--dtdeypN--RPF------S---DV 691 
WP_015751527  590 angt------------------tqrfkrvpryteLA-RIRLEQSYDFReatrqd--dreqypR--RPF------S---DI 637 
WP_013164430  599 ppapddsalaingpaepeplalptsppgdfwsrpLA-FFKMMQTYDIDearrdl---eadesR--REL------S---DL 663 
WP_013375762  658 -------------------------------lrePL-RLRVGQGFDLTryaplwk---easnqeaPIL------R---DT 693 
WP_013513763  617 sgee-------------------pqvstvsdyldFL-LFRVEQSYDRKeatrnd--elavykR--RPY------S---DL 663 
YP_010175     582 pdse------------------eeyqkvaydyldVI-RWRLESGYDLRemdrnd--dledypR--RPF------M---DM 629 
WP_015353660  609 nnnnd----------------nsvtptlitsyydLL-YWNLSTGYDFEeerrkq--yvekypK--RPI------K---DI 658 
WP_095975860  647 -------------------------------rreLL-RLTVGQGFDLSrhaptfgqgsvlesD--PVT------R---DT 683 
WP_095986079  656 -------------------------------reeLL-RLSVGQGFDLSrfapspgggpsesdQ--PLA------R---DT 692 
WP_064536588  867 AINLEPlKPMSpYkNLEMNpALYykieprylDYLKfvflaayDpLiNRvSE--LSFKVn---AYDFKFEFaMKN 935 
WP_081434329  692 LTDLTT-RLSPwL-YLNNK-TWF--------SPYEg------Q-I-IE-HEhsLSAYYdslvYATFSLDF-LEE 744 
WP_015751527  638 LVDIET-GIAPwL-RLDNK-TWF--------SPYLg------T-I-TE-HEhlLRGTWpevgSCFFGLDY-HKQ 690 
WP_013164430  664 RFDLQA-SPLPsL-DLRYQ-TNL--------SMYGq------G-V-NR-YElqGTYRRfg-gsLTLNYRY-LKH 715 
WP_013375762  694 FARLLA-RVGI-F-SAGAL-VRY--------DTQNa------Q-I-SQ-LSaeAHVDNg---RGEALYAR-YDD 742 
WP_013513763  664 MTEVVV-KPENfI-DLVSR-VWF--------SPYKt------S-L-TQ-NEnyVRLHQdglgEITLGYDY-LVK 716 
YP_010175     630 ISDLRF-GVFDwL-SIYTR-SDW--------SPYLg------D-F-TR-HDqgVTFTSqrwgYISTGYSY-RPK 682 
WP_015353660  659 YSELEL-YILSwL-TYSGK-TFI--------SPYNg------N-I-TR-HDhnIIFKSdrfsW-KTGLSF-RDQ 710 
WP_095975860  684 FGRLSA-QLGS-I-SGGGT-LRY--------DPNSn------Q-I-AQ-LSadFRVDVp---NGD-IYAR-YDD 731 
WP_095986079  693 FGRLSA-RLGR-F-SGTGV-LRY--------DPNSr------Q-I-TQ-LSadFRVDVp---HAN-LYAR-YDD 740 
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