225620277 1 MRKQDEGNETMKEIASHVRSGAIAYLKQQYKVIAFFFAGAFIIFail-----syaLKVQNPFIPIGFLTGGFFSTLSGFL 75 302864951 43 VLAAGKGTTNMQEISGAVQEGASAYLLRQFRTLAIFVVIAVVLLfllpvhdtdgnETLVKAGRSAFFVVGALFSAFIGGA 122 271962068 45 VLAAGQGTERMQNIARAVQEGASAYLARQFRTLAVFVILIPFLLyll-----paeSTGVAIGRSVFFVVGAVFSALTGFI 119 297564247 45 VLAAGQGTERMRGIALAVQEGAAAYLKRQFRTLAVFVVLIPLLLlll-----padSWAIAIGRSVFFALGALLSAATGFI 119 269129011 46 VLAAGQGTEKMRNIARAVQIGAGAYLKRQFRTVAIFVVLIPLLLlll-----padDMAVRIGRSVFFVIGALFSAITGFA 120 72160538 73 VLAASQGTERMQNIARAVQEGAAAYLKRQFRTLAVFVIIIPLLLlll-----padTEAVRWGRSIFFAIGALFSAMTGFL 147 145596541 43 VLAAGRGTTNMQEISGAVQEGASAYLLRQFRTLAIFVVVAVLLLfllpvhetdgsETAVKIGRSAFFVIGALFSAFIGGA 122 159039926 43 VLAAGRGTTNMQEISGAVQEGASAYLFRQFRTLAIFVVVAVLLLfllpvhdtdgsETAVKIGRSAFFVVGALFSAFIGGA 122 291298029 42 VLATGKGTKKMQEIAGAVQEGASAYLKRQFRTLAIFVVIAMVLLwflpvhdvgdsETMVKAGRSAFFVVGAGFSAFIGWA 121 296268216 44 VLSAGQGTERMQNIARAVQEGAAAYLARQFRTLVVFVVVIPLLLlll-----papSTSVQIGRSVFFVVGALFSALTGFM 118
225620277 76 GMKTATYASARTANAA--SK--SLNEGLTIAFRSGAVMGLTVVGLALFDISLWFIVLNvwldnslfgtdflnlaatgiak 151 302864951 123 GMWLATRANLRVAAAAreREg-GREAAMKIAFRTGGVVGFLTVGLGLFGAALVVLIFR---------------------- 179 271962068 120 GMWLAVRGNVRVAAAAreS---GEKVAMRIAFRTGGVAGMITVGLGLLGAAIVVIVYG---------------------- 174 297564247 120 GMWLAVRGNVRVAAAArgGDdaSNRTAMRIAFRTGGVAGMITVGLGLFGAALVVLLYR---------------------- 177 269129011 121 GMWLAVRGNVRVAAAArdGDaaAERRAMRLAFRTGGVAGMFTVGLGLFGAAVVVLSYQ---------------------- 178 72160538 148 GMWLAVRGNLRVAAAAraG---EARAAMRIAFRTGGVAGMFTVGLGLLGAALVVLIYR---------------------- 202 145596541 123 GMWLATRANLRVAAAAreRVg-GRETAMRIAFRTGGVVGFLTVGLGLLGAALVVLFYR---------------------- 179 159039926 123 GMWLATRANLRVAAAAreRAg-GREAAMRIAFRTGGVVGFLTVGLGLLGAALVVLFYR---------------------- 179 291298029 122 GMGLATRANLRVASAArdG---SRTGAMAIAFRTGGVVGFLTVGLGLLGAAVVVMVFK---------------------- 176 296268216 119 GMWLAVRGNLRVAAAAkdQ---GEKAALRIAFRTGGVAGMFTVGLGLLGAAIVVLVYK---------------------- 173
225620277 152 gtaeytaakmHFVTTTMLSFGVGASFQALFARVGGGIFTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAG 231 302864951 180 ----------GDAPTVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQGIPEDDPRNAATIADNVGDNVGDCAG 249 271962068 175 ----------GDAPAVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQGIPEDDPRNAATIADNVGDNVGDCAG 244 297564247 178 ----------GDAPIVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQGIPEDDPRNAATIADNVGDNVGDCAG 247 269129011 179 ----------GGAPGVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQGIPEDDPRNPATIADNVGDNVGDCAG 248 72160538 203 ----------ADAPIVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEHHIPEDDPRNAATIADNVGDNVGDCAG 272 145596541 180 ----------GDAPTVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQGIPEDDPRNAATIADNVGDNVGDCAG 249 159039926 180 ----------GDAPTVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQGIPEDDPRNAATIADNVGDNVGDCAG 249 291298029 177 ----------GNAATVLEGFGFGAAMLAMFMRVGGGIFTKAADVGADLVGKVEQGIPEDDPRNAATIADNVGDNVGDCAG 246 296268216 174 ----------GDAPNVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQGIPEDDPRNAATIADNVGDNVGDCAG 243
225620277 232 MGADLYESYAGSILAAMSLGSaafgyinpDVSPIFAVSLPMILAAIGTLSSIIGVFFVKTKEGatmGELLKSLRVGVYVS 311 302864951 250 MAADLFESYAVTLVAALILGR--------AAFGETGLVFPLIISTIGVLVAIVGVFITRLRASd--RNGLTAINRAFYLS 319 271962068 245 MAADLFESYAVMLVASLILGK--------VAFGTEGLVFPLIVPMVGVITAIIGIFTTSPRKGd--RNGMAAINRGFFIS 314 297564247 248 MAADLFESYAVVLVASLILGR--------VAFGTEGLVFPLLVPMIGVLTAIVGIFLVAPRARd--KTAMSAINRGFFIS 317 269129011 249 MAADLFESYAVTLVAALILGT--------VAFGTHGLVFPLIVPMIGVITAMIGIFAVAPRARd--RSGMTAINRGFFIS 318 72160538 273 MAADLFESYAVVLVASLVLGR--------VAFGTEGLVFPLLVPMIGVITAIIGIFVVSPRARd--ANAMAAINRGFFIS 342 145596541 250 MAADLFESYAVTLVAALILGR--------AAFGEQGLVFPLIVSGIGVIVAIIGVFITRLRTSd--RSGLTAINRAFYAS 319 159039926 250 MAADLFESYAVTLVAALILGR--------AAFGEEGLVFPLIVSGIGAIVAIIGVFITRLRASd--RSGLTAINRAFYAS 319 291298029 247 MAADLFESYAVTLVASLILGQ--------IAFGDTGLVLPLIIGAVGIVTAIFGVFITKLRASd--KNGLTAINRAFFIS 316 296268216 244 MAADLFESYAVTLVASLILGK--------AAFGTEGLVFPLLVPMIGVLTAIIGIFAVRTRSGd--RSGMAAINRGFFIS 313
225620277 312 SAIIIIVAFLLVKALLP-------------------------NNLGL----------FVSIIVGLIAGNVVGFFTEYYTA 356 302864951 320 ALIAAVLVAIAAFAYLPatf-------------------aelEGGLTdvdrnprlvaIGAVVIGIVLAAAIQALTGYFTE 380 271962068 315 AVISAVLVGVAVFLYLPssfag----------------ltgvSPEIAaitsdprliaIGAVLIGLVLASAIQILTGYFTE 378 297564247 318 AAISAVLVVGTAFWYLPssfdqlsgvspqvlaeieeagtnpdPRILA----------VAAVLIGLVLAAAIQLLTGYFTE 387 269129011 319 AIISALLVAVAAYGYLPssfael--------------ggvtdPQITAleadp-rlvaLGAVLIGIVLASAIQLLTGYFTE 383 72160538 343 AVISAVLVVGAALLYLPdtfael--------------egvpaDIAALdgnp--qliaIGAVLIGLLLAAAIQLLTGYFTE 406 145596541 320 ALISAVLVAIAAWTYLPasf-------------------aelTQGLAdvdqnprvvaIGAVVIGIVLAAAIQALTGYFTE 380 159039926 320 ALISAVLVAIATWAYLPatf-------------------gelAGGLTgvnenprvvaLGAVVIGIVLAAAIQALTGYFTE 380 291298029 317 AVLAAVLSAGAILATVPntwaalgvee------avhkgvpfsPQVTA----------IVAVVIGIVLAAAIMALTGYYTE 380 296268216 314 AVISAILVAVAAFAYLPssfael--------------sgvseEIRALtadp--rliaLGAVLIGLVLASLIQLLTGYFTE 377
225620277 357 AEYRPTQWVAEQSKTGPATVIIGGLAVGMQSTLIPVVTVVISIILAFGFaggfgaeasafsQGLYGIALASVGMLSTLGI 436 302864951 381 TNRRPVQDIGKSSQTGPATVILAGISVGLESAVYSALLIGAGVFGAFLLggs------sitLSLFAVALAGTGLLTTVGV 454 271962068 379 TNRRPVKDIGESARTGPATVILSGISVGLESAVYSALIIGAAVYGAFLLgfg------nvtIALFAVALAGTGLLTTVGV 452 297564247 388 TDRRPVREIGDSSETGAATVILSGISVGLESAVYSALLIAGAVYAAFLLggg------sitLSLFAVALAGTGLLTTVGI 461 269129011 384 TTRRPVREVTASARTGPATVVLSGISLGLESAVYSALVIGAAVYGAFLLgfg------nttVALFAVAMAGTGLLTTVGV 457 72160538 407 TNRPPVREIGESSRSGPATVVLAGVSVGLESAVYSALLIAGAVYAAFLLggg------nitVSLFAVALAGTGLLTTVGV 480 145596541 381 TDRRPVQDIGRSSQTGPATVILAGIGVGLESAVYSALLIGAGVFGAFLLggs------sitLSLFAVALAGTGLLTTVGV 454 159039926 381 TNRRPVQDIGRSSQTGPATVILAGIGVGLESAVYSALLIGAGVFGAFLLggs------sitLSLFAVALAGTGLLTTVGV 454 291298029 381 TEKRPVSDVAKTSLTGPATVILSGVSLGFESAVFSALVIGAGVYGAFLLggat-----amfVSLFAIALAGCGLLTTVGV 455 296268216 378 TNRRPVREIGESALTGPATVILSGVAVGLESAVYSALLIGAAVYGAFLLgfg------nvtVALFAVALAGTGLLTTVGV 451
225620277 437 TLATDAYGPIADNAGGNAEMS-GLPESVRERT-DALDSLGNTTAATGKGFAICSAALTAMALIAAYIEEIktslgrmint 514 302864951 455 IVAMDTFGPISDNAQGVAEMS-GDIDEHGARTlTELDAVGNTTKAITKGIAIATAVLAATALFGSYTDTLrsay------ 527 271962068 453 IVSMDTFGPVSDNAQGIAEMSgDVDGEGARVL-TSLDAVGNTTKAITKGIAIATAVLAATALFGAFRTAIetqlan---- 527 297564247 462 IVAMDTFGPVSDNAQGIAEMSgDVEGPGAEIL-TGLDAVGNTTKAITKGIAIATAVLAATALFGAFRTSVq--------- 531 269129011 458 IVSMDTFGPVSDNAQGIAEMSgDVHGEGAKVL-ERLDAVGNTTKAITKGIAIATAVLAATALFGAYRTTVetalag---- 532 72160538 481 IVAMDTFGPVADNAQGIAEMSgDVEGSGAEVL-NSLDAVGNTTKAITKGIAIATAVLAATALFGAFRTAV---------- 549 145596541 455 IVAMDTFGPISDNAQGVAEMSgDIDADGARTL-TELDAVGNTTKAITKGIAIATAVLAATALFGSYTDTLriay------ 527 159039926 455 IVAMDTFGPISDNAQGVAEMSgDIEADGARTL-TELDAVGNTTKAITKGIAIATAVLAATALFGSYTDTLrtay------ 527 291298029 456 IVAMDTFGPISDNAQGIAEMSgDIDEEAARTL-TDLDAVGNTTKAITKGIAIATAVLAATALFGSYTSAInval------ 528 296268216 452 IVSMDTFGPVSDNAQGIAEMSgDVDGEGAQVL-TSLDAVGNTTKAITKGIAIATAVLAATALFGSFRTAVetelaa---- 526
225620277 515 gnltsidigtvqytansakelydkvvysLGMNEFMNAFNIHLMNPKVLIGIFIGAMLVFFFCALTMKAVGRAAAGVVEEV 594 302864951 528 ------------------------edagVGDVGTEILNSLNVSNPRNLVGLIIGAAVVFLFSGLAINAVSRSAGAVVMEV 583 271962068 528 -----------------------asqgvKDVLGSFGTFSLSVDSPNVLVGLIIGAAVVFMFSGLAIMAVGRAAGRVVFEV 584 297564247 532 ----------------------------AQLGDADEAFSLSLDQPDVLVGVIIGASVVFFFSGLAIMAVGRAAGRVVMEV 583 269129011 533 -----------------------asagvRDALGTYADFSLSIDSPNVLIGLIVGAAVVFLFSGLAIMAVSRAAGRVVIEV 589 72160538 550 -----------------------------EAELGATEFSLSVDQPDVLVGVIIGAAVVFLFSGLAIMAVGRAAGRVVHEV 600 145596541 528 ------------------------adagITDVGGEILNSLNVANPRNLVGLIIGAAVVFLFSGLAINAVSRSAGAVVMEV 583 159039926 528 ------------------------adagIADVGGEILNSLNVANPRNLVGLIIGAAVVFLFSGLAINAVSRSAGAVVMEV 583 291298029 529 -------------------------aegGKLADGGIDVLLNIANPANIVGVIVGAAVVFLFSGLAVNAVSRSAGAVVFEV 583 296268216 527 -----------------------atqgvKDVLGSFASFSLSVDAPNVLVGLVIGASVVFLFSGLAINAVGRAAGRVVIEV 583
225620277 595 RRQFREIKGLLAGEkgVKADYEKAVQICTKSAQKEMIVPSVLAIIVPVVVGFLFGVPAVIGMLVGGLTAGFAMAVMMSNA 674 302864951 584 RRQFRELPGIMDRT--QRPEYGKVVDICTRDAQRELMTPGLLAILAPIAVGFGLGPGALAAYLAGAIGAGTLMAVFLANS 661 271962068 585 REQFRTKPGIMAGT--ELPDYGRVVDICTRDSLRELATPGLLAVLTPIAVGFALGYAPLGAFLAGAIACGTLMAVFLANS 662 297564247 584 RDQFRTRPGIMDGT--EKPEYARVVDICTKDSLRELVTPGLLAVLAPIAVGFALGYAPLGAFLGGAIAAGVLMAVFLSNS 661 269129011 590 REQFRSKPGIMNHT--QEPDYDRVVDICTRDSQRELATPGLLAIMTPIAVGFGLGYAPLGAFLGGAIAAGVLMAVFLANS 667 72160538 601 REQFRTRPGIMDGT--EKPEYGRVVDICTRDSLRELITPGLLAVLTPIALGFALGYAPLGAFLGGGIAAGALMAVFLANS 678 145596541 584 RRQFRELPGIMDRT--QRPEYGKVVDICTRDAQRELLTPGLLAIMAPIAVGFGLGPGALASYLAGAIGAGTLMAVFLANS 661 159039926 584 RRQFRELPGIMDRT--QRPEYGKVVDICTRDAQRELMTPGLLAILAPIAVGFGLGPGALASYLAGAIGAGTLMAVFLANS 661 291298029 584 RRQFREFPGIMDGT--QRPEYGRVVDICTRDAQRELMTPGLLAILAPIAVGFGLGAGALAAYLAGAIACGVLMAIFLANS 661 296268216 584 RDQFRNKPGIMDGT--EKPDYGRVVDICTRDSLRELATPGLLAVLTPIAVGFALGYAPLGAYLAGAIAAGTLMAVFLANS 661
225620277 675 GGAWDNAKKYIEAGNLGGKkiidektgekiTNPNHAAAVIGDTVGDPFKDTSGPSINILIKLMSLISVVFAGAIVA 750 302864951 662 GGAWDNAKKLVEDGAYGGK-----------GSDAHSATVIGDTVGDPFKDTAGPAINPLIKVMNLVSLLIAPAVVA 726 271962068 663 GGAWDNAKKLVEDGHHGGK-----------GSSAHEATIIGDTVGDPFKDTAGPAINPLLKVMNLVALLIAPAVVT 727 297564247 662 GGAWDNAKKLVEDGHHGGK-----------GSEAHAATVIGDTVGDPFKDTAGPAINPLLKVMNLVALIVAPSVVI 726 269129011 668 GGAWDNAKKLVEDGKLGGK-----------GSEAHAATVIGDTVGDPFKDTAGPAINPLIKVMNLVSLLIADAIVT 732 72160538 679 GGAWDNAKKLVEDGHYGGK-----------GSEAHEATVIGDTIGDPFKDTAGPAINPLLKVMNLVALLIAPSVVI 743 145596541 662 GGAWDNSKKMVEDGAYGGK-----------GSEAHAATVIGDTVGDPFKDTAGPAINPLIKVMNLVSLLIAPAVVA 726 159039926 662 GGAWDNGKKMVEDGAFGGK-----------GSEAHAATVIGDTVGDPFKDTAGPAINPLIKVMNLVSLLIAPAVVA 726 291298029 662 GGAWDNAKKAVEDGAHGGK-----------GSEAHDATVIGDTVGDPFKDTAGPAINPLIKVMNLVSLLIAPAVIM 726 296268216 662 GGAWDNAKKLVEDGHHGGK-----------GSEAHAATVIGDTVGDPFKDTAGPAINPLIKVMNLVALLIAPAVVA 726