Conserved Protein Domain Family
MIase

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pfam02426: MIase 
Muconolactone delta-isomerase
This small enzyme forms a homodecameric complex, that catalyzes the third step in the catabolism of catechol to succinate- and acetyl-coa in the beta-ketoadipate pathway EC:5.3.3.4. The protein has a ferredoxin-like fold according to SCOP.
Statistics
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PSSM-Id: 426768
Aligned: 69 rows
Threshold Bit Score: 77.6025
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q73Y30          110 EFLQAITIRVPADAPQRVVDDVLAREAERAGELGAQGCLQRLWWLhsgPGEPRVLALWRTADTESLAA-VLRSLPLHA-- 186 Mycobacteriu...
tigr:MSMEG_4045   4 EYLVRIDVERPATVPDAEWDAVMAREAERARGYRRAGVIVRIWRI---PGTRSNVGIWSAASASELHD-KLSALPAHP-- 77 
EHR51821         14 EFLVRADNNLPPDMPEQRRNELRAAERERAVRLREDGTLQRLWRV---PGRTGWIGLFEAPDATALHD-ALASLPLWP-- 87 
WP_014376357      2 EFLVRSENRLPADTPAERREELRAGERARAMELRAAGVLKRLWRV---PGRNATIGLYEAEDPAALHD-ALMSLPMAP-- 75  Blastococcus
WP_013675793      2 EFLVRAENRLPVETPDEERNRLKKGERARADELRAAGILKRLWRV---PGRNATIGLYEVGDATELHD-VLASLPMFP-- 75  Pseudonocard...
jgi:Cwoe_2367     2 EFLVDVRVSLPPEMAAEQRQQLLAAELKRGRELVAAGHIQGIWRI---PGAVRNVGIWNARDATELHQ-LIASLPLFP-- 75 
Q82MX8          120 EFLVEITTTIPEGTEPAEVDRRRAAEAVRAEELAATGNLFRLWRP---VGELRSIGVWRAADEDELHEkVLGTLPLRS-- 194 Streptomyces...
wustl:cce_4516    9 LYLLDFQVEYGPDMTQKDLFSVWSKEAEAALNAKKAGVVVDLWKC---VGERRVIAIVNVESPDILDQ-ILFSLPIMKam 84 
WP_015691816      8 EFEVPAEMQ-------SHVEARSAEHHAKVEELMAQGRIQSFSYS---ANALRSWAIVRASSAIEVMR-LIQELPLQD-- 74  Saprospira g...
WP_025436443      2 LFLVKTKVKEKYMPKLQELYGTIMEQMDMIVALQQQGKIVFSGKV---AEQIASVLIMDMESRQELDE-SIQAMPGAD-- 75  Peptoclostri...
Q73Y30          187 --WLQVDtTTPLHTHPDD 202 Mycobacterium avium subsp. paratuberculosis
tigr:MSMEG_4045  78 --YMKID-VQPLAQHYve 92 
EHR51821         88 --WLDVT-VEPLATHPQe 102
WP_014376357     76 --WLDVH-VEALATHPQe 90  Blastococcus
WP_013675793     76 --WMDIS-VEAVATHPQe 90  Pseudonocardia dioxanivorans
jgi:Cwoe_2367    76 --WLAAD-VTALATHPln 90 
Q82MX8          195 --WMTLT-VTPLESHPND 209 Streptomyces avermitilis
wustl:cce_4516   85 gqYVNVK-VTSLRRYedf 101
WP_015691816     75 --CMIPS-IISLESHHAa 89  Saprospira grandis
WP_025436443     76 --IFEIE-ITPLEDfqah 90  Peptoclostridium acidaminophilum
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