Conserved Protein Domain Family
egtB_TIGR03440

?
TIGR03440: egtB_TIGR03440 
ergothioneine biosynthesis protein EgtB
Members of this family include EgtB, and enzyme of the ergothioneine biosynthesis, as found in numerous Actinobacteria. Characterized homologs to this family include a formylglycine-generating enzyme that serves as a maturase for an aerobic sulfatase (cf. the radical SAM enzymes that serve as anaerobic sulfatase maturases). [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]
Statistics
?
PSSM-Id: 274581
Aligned: 28 rows
Threshold Bit Score: 381.291
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_011563675  13 ISRELEEARERTRWLISPLSEEQ--LTAQHDPIMSPLIWDYGHIGNYEELWLLNR------------------AFGRS-L 71  Rubrobacter xyl...
WP_011119788  26 MLDAYRRVREHSRKICAPLETED--YVIQSMPDVSPTRWHLAHTTWFFETFCLKN------------------LPDYE-P 84  Rhodopirellula ...
WP_015951629  32 WIAAFRTVREETERRAAPLSPED--QQIQSMEDASPTKWHRAHTTWFFEQFLLGDh-----------------QPGYR-L 91  Methylobacteriu...
WP_011597827   7 IETVLTRARERTAGLTDCVDGED--LVAQHSPLMSPLVWDLAHIGNQEELWLVRD------------------VGGRE-P 65  Rhodococcus jostii
WP_010988735  17 ALDALTTARERTALLTTCVDEPD--LTAQHSPLMSPLVWDLAHIGNQEELWLLRA------------------VAGRD-A 75  Streptomyces av...
WP_010996864  19 IAFALEECRTKTLSLFVGMDAAT--FCCQPHADFSPVGWHLGHIAYIESLWVL-Eh-----------------SADLP-C 77  Nostoc sp. PCC ...
WP_011557378  26 AWTELETARARVLAMLGGLPEDE--LRRQHSPLMSPLIWDVAHVANYEEQWLLRA------------------LGAPA-I 84  Myxococcus xanthus
WP_011562257   7 LADELGRARDRTLRLVD-FDDME--LRRQYDPLMSPLVWDLAHIGQQEEFWLLRDg-----------------NADRPgM 66  Mycobacterium
WP_011000903  30 IAHSLVDARNRTLALLAAFGDTQrgWQIERVLHHAPPLWTLGQLAWFAEFWCLREprrvgedavedgggtewaLPRWQ-A 108 Ralstonia solan...
WP_011141636  16 LPQRLFATREATFAMLAGVEREH--FCRQAHPDYSPVGWHLGHIAFTEGLWILER------------------CAGLP-R 74  Gloeobacter vio...
WP_011563675  72 ADRELYDIYDAS------ITPRSERPSLNMLGRADADRYLDAVRRAALEELR----KA-DlggddplL-GEGFVYRMVLQ 139 Rubrobacter xyl...
WP_011119788  85 EQPAFEVLFNSYynsvgeQFPRDRRGLLSRPTVAEVWRYRDQVDEAMFELLA----RS-Dr-----dSiVTDEVLRTGMN 154 Rhodopirellula ...
WP_015951629  92 FDERLHYLFNSYyvqagpRQPRFMRGMITRPTAQETAGYRAHVDRAVSVWLR----EA-Sde---alA-RALPILEIGLY 162 Methylobacteriu...
WP_011597827  66 VRRDIDELYDAF------KHSRNSRPSLPLLNPDEAREYVRTVRDKSWDVLD----RS-Tfrg-rplE-ENGFAFGMIAQ 132 Rhodococcus jostii
WP_010988735  76 MRPEIDGLYDAF------EHPRAERPSLPLLPPDEARRYASEVRGRALDVLEstafRG-Tp-----lT-EAGFAFGMIAQ 142 Streptomyces av...
WP_010996864  78 LFPQYRQLFAAD------GLPKKQRGQL--PEIAEIVYYLDTVRAKVLEYLE----VA-Di------Q-QQERLWRFLIQ 137 Nostoc sp. PCC ...
WP_011557378  85 TDPAFDAIYDAF------RHPRSTRAELPLLPPEAAFAYARRVREAVREHLH----RL-PedstaplL-AGGYVFGMVAQ 152 Myxococcus xanthus
WP_011562257  67 LAPGVERLYDAFvn------sRATRVNLPLLPPTDARAYCRTVRDKVLDSLD----AL-Pd-----dDaENAFRFALVIS 130 Mycobacterium
WP_011000903 109 TLPAGLDGADSFfd--mdRMPPDACWALTLPGIATIKQYAHDVLDRVLRKLA----TLgTd-----eD-AALEPFRWAVF 176 Ralstonia solan...
WP_011141636  75 PAPEFGRIFAVD------ALPKAQRTSL--PATAEIYGYVRQVREQVLACLD----RE-Pg-----lS-AEARLWHFLVQ 135 Gloeobacter vio...
WP_011563675 140 HEAQHNETMLQtL-QLMRGEGYRPRRMA-PLPP-GNPGGEEMVLVPGGAFI-MG-TDD--RA---RALDNERPAHEVELP 209 Rubrobacter xyl...
WP_011119788 155 HEQQHQELMLTdLlHVFSCNPLHPVYCDdAVTDcDPVEEVRWIESPVERIEpVG-FDE--SShglFCFDNELPRHRALLS 231 Rhodopirellula ...
WP_015951629 163 HEQQHQELMLTdIlHAFAQNPLDPVYDA-RWSLpAAQASAGQSALKRGITQ-IG-YDG--HG---FAFDNESPRHDVLML 234 Methylobacteriu...
WP_011597827 133 HEQQHAETMLAt--HQLRTGPAVLAAES--APRvGGAIDEDEVVIPSGEFT-MG-TSD--DP---WALDNERSAHRVHVP 201 Rhodococcus jostii
WP_010988735 143 HEQQHDETML--ItHQLRKGPAALTAPD-PAPApPFTGPAE-VLVPGGPFT-MG-TSA--EP---WALDNERPAHERLVP 211 Streptomyces av...
WP_010996864 138 HESQHCEIITMvLeLLNCQLPTVNCQLS-TVNHqQLNSVGEMVEIPAGEFE-LG-NDS--ID----ALDNERPAHRVYLD 208 Nostoc sp. PCC ...
WP_011557378 153 HEQQHAETLAAtLqLMTSPEYHVPSARP-R--PrPGAVPQAEVFIPGGEAR-LG--ST--SP---WAYDNERPTFSQHVA 221 Myxococcus xanthus
WP_011562257 131 HENQHDETMLQaL-NLRTGAPLLEAGAA-L-PAgRSGVAGTAVSVPGGPFV-LG-VDAvtEP---HSLDNERPAHIVDVP 202 Mycobacterium
WP_011000903 177 HEDLRAEH----LhGLLQVLGLQPAGQP-P-LAaVVVPAARTLSLPGGRFQ-MGwPDA--DG---FVFDNECPPHRTYVP 244 Ralstonia solan...
WP_011141636 136 HESQHAETMRW-LlQLLTPTPAGEAIFS-G------ADTDEMIRVEPGEAL-MG-SDA--TE----ALDNERPARQVHLE 199 Gloeobacter vio...
WP_011563675 210 PFYIDRLPVTNREYLGFVEDGGYRREELWDPEGWEWIREERISAPKHWYQkE--PHDWWTECFGFDQPLRPDAPVMHVSW 287 Rubrobacter xyl...
WP_011119788 232 PHAIANRLVTNGEYLEFIEDGGYDDPSYWLSAGWATVQSEGWRAPMYWHL-G--EEGWHQFTLAGLRPVDEKAPVCHVSY 308 Rhodopirellula ...
WP_015951629 235 EARIDRGLVTNRDWLAFMEDGGYARPELWLNDGWVALQREGWEAPGYWRR-E--ADGWSTMSLAGRKPVDPAAPAAHVSY 311 Methylobacteriu...
WP_011597827 202 AFVIDAVPVTNGRYLEFMDDGGYARPEFWSERGWAHRLEAGLDAPQFWEN-Dg-CGTWWRRRFGVTEPIHLQEPVVHVCY 279 Rhodococcus jostii
WP_010988735 212 SFYLDTTPVTNAAYQAFIEDGGYGDERWWTAEGWDHIRSHSIEAPLYWRR-E--QGQWLRRRFGVTEPVPPNEPVLHVCW 288 Streptomyces av...
WP_010996864 209 TYWIDRYPVTCGEYGVFIEAGGYQNPEWWSVAGWKWLQTEQVIQPLYWNR---------------LSSTTENHPVYGVSW 273 Nostoc sp. PCC ...
WP_011557378 222 PFLMDAHPVTNGDYLVFVEAGGYEDPRWWHPKGWEVIQAEGLKYPGFWLP-Qg-NHTWLRRRFGQVEPLPKDEPVQHVCW 299 Myxococcus xanthus
WP_011562257 203 GFRIGRVPVTNGEWQQFVDDGGYSQRQWWSAAGWAHRQEAGLTAPQFW------NGDGTRTRFGHVEQIPADEPVQHVTF 276 Mycobacterium
WP_011000903 245 AFEIDAQPVTNGQYLEFVEDGGYDHPQWWSAAGMEWLMMQERSAPLGWRR-DpaSRTWQVVRYGQPRTLNRDEPARHVSL 323 Ralstonia solan...
WP_011141636 200 GYWIDRYPVTQRQFQAFIDTGGYGEPHFWSASGRRWLSQHPVHRPLYW-------------------SAPDDRPVMGVSY 260 Gloeobacter vio...
WP_011563675 288 YEADAYARWAGKRLPTEAEWEKAASwdpeegtkrlfpWGDEPPTPERANLDqla----frpAEVGAYPAG--AspCGALG 361 Rubrobacter xyl...
WP_011119788 309 FEADAFARWSGCRLPTEFEWEIAVR------------DS---------------------------------R--ESMID 341 Rhodopirellula ...
WP_015951629 312 YEADAYARWAGRDLPTEAEWEVAAR------------DG-------------------------------------LIDD 342 Methylobacteriu...
WP_011597827 280 FEAEAFARWDGKRLPTEAEWEKAARwdpftgrsrrfpWGDAEPDSSLANLGqrh----lgpAVVGAYPSG--AspLGVHQ 353 Rhodococcus jostii
WP_010988735 289 YEADAYARWAGRRLPTEAEWEKAARhdpvtgrstrypWGDADPTPEHANLGqrh----lrpAPAGSYPAG--AspLGVRQ 362 Streptomyces av...
WP_010996864 274 YEAEAYARFVGKRLPTEVEWEKAASwnvkadcrhtypWGEDMPTPQNCNCDglrrglgektTPVNAYPAGqsA--YGIYD 351 Nostoc sp. PCC ...
WP_011557378 300 YEADAYARWAGKRLPTEAEWEKAARgsdgr--preypWGDTPPTRARANLDgst----wgpAPVGSYPQGvsQ--DGVWG 371 Myxococcus xanthus
WP_011562257 277 FEAEAYARWAGARLPTEIEWEKACAwdpaagqrrrypWGSSAPTAHLANLGgda----lrpAPVGAYPAGasA--YGAEQ 350 Mycobacterium
WP_011000903 324 YEAQAWCRWAGRRLPTEDEWEMAAV------------LG-------------------------------------RAGF 354 Ralstonia solan...
WP_011141636 261 YEAEAYARFACKRLPTEAEWEKAARydptrgtfrtypWGEVPPEAGRTGTGr---------AAVGIHPAGrsA--LGLDD 329 Gloeobacter vio...
WP_011563675 362 MVGDVWEWTATEFSGYPGFES--FP--YREYSEVFF-DeG-----YMVLRGGSFATRPCAIRNTFRNWDFPIRRQLFVGF 431 Rubrobacter xyl...
WP_011119788 342 AFGTRWQWTASDYAPYPKYAA--PEgaIGEYNGKFM-C-G-----QKVLRGSSVATPEGHARLTYRNFFPPSMRWQFCGI 412 Rhodopirellula ...
WP_015951629 343 AFGLVWQWTRSAYGPYPGYRP--VPgaLGEYNGKFM-S-N-----QYVLRGSSVATAQGHARVGYRNFFYPHQRWQFTGL 413 Methylobacteriu...
WP_011597827 354 LIGDVWEWTSSPFEPYPGFSA--FP--YREYSEVFY-G-Gd----YRVLRGGSFGTDPVACRGTFRNWDHPIRRQIFSGF 423 Rhodococcus jostii
WP_010988735 363 LIGDVWEWTSSDLEPYPGFTA--FP--YKEYSEVFF-GpE-----HKVLRGGSFAVDPVACRGTFRNWDYPIRRQIFSGF 432 Streptomyces av...
WP_010996864 352 TLGNVWEWTASWFDGYKGFQS--YP--YKGYAQVYF-DqK-----HRVLKGGSWATRPWVLRPSFRNWYHPQVRQIFAGF 421 Nostoc sp. PCC ...
WP_011557378 372 LLGDVWEWTASDFRPYAGFSA--FP--YPEYSEVFF-GeS-----YKVLRGGAWASAPVAMRNGFRNWDFPNRRQIFAGF 441 Myxococcus xanthus
WP_011562257 351 MLGDVWEWTTSTLRPWPGFTP--MI--YDRYSQPFF-D-GtgsgdYRVLRGGSWAVAPEILRPSFRNWDHPIRRQIFSGV 424 Mycobacterium
WP_011000903 355 HWGQVWEWTSSPFEPYPDFVPgaPRgrVATLSAPHF-M-T-----MQTVRGAAAHTPQRVRHPRFRGFLLPERDDVFVGF 427 Ralstonia solan...
WP_011141636 330 LLGNVWEWTATWFHPYPGFVS--YP--YTGYSAAYFdD-G-----HRVLKGGSWASGPAVLRPSFRNWYEPAQRVPFAGF 399 Gloeobacter vio...
WP_011563675 432 RCA 434 Rubrobacter xylanophilus
WP_011119788 413 RLA 415 Rhodopirellula baltica
WP_015951629 414 RLA 416 Methylobacterium extorquens
WP_011597827 424 RCA 426 Rhodococcus jostii
WP_010988735 433 RTA 435 Streptomyces avermitilis
WP_010996864 422 RCA 424 Nostoc sp. PCC 7120
WP_011557378 442 RCA 444 Myxococcus xanthus
WP_011562257 425 RLA 427 Mycobacterium
WP_011000903 428 RTC 430 Ralstonia solanacearum
WP_011141636 400 RCA 402 Gloeobacter violaceus
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap