3GGG,7MQV,3DZB,3KTD


Conserved Protein Domain Family
TyrA

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COG0287: TyrA 
Prephenate dehydrogenase [Amino acid transport and metabolism]
Prephenate dehydrogenase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Statistics
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PSSM-Id: 440056
Aligned: 713 rows
Threshold Bit Score: 145.654
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3GGG_A        34 QNVLIVGVGFMGGSFAKSLRrsgFKGKIYGYDINPESI-SKAVDLgiidEGTtSIAK-VEDfsPDFVMLSSPVRTFREIA 111
WP_013446199   1 MKILVLGAGKMGTFLTDVLC---INHEVALFDTDPKRLrFVFNTL----RMT-EYEEiWAFe-PELVINCVTLKYTIDAF 71 
WP_005856360   1 MKILILGAGKMGSFFTDLLS---FDHEVAVLEKDPKRMrFIYNAL----RLQ-SPEEvKDFn-PELVINCVTLSYTIEAF 71 
NP_812844      1 MRILILGAGKMGSFFTDILS---FQHETAVFDVNPHQLrFVYNTY----RFT-TLEEiKEFe-PELVINAVTVKYTLDAF 71 
WP_079558014   1 MKICVLGAGKMGTWLTDALC---LQHEVAIYDVDKERLrYVFNTQ----RLT-TLEEiREFa-PELLINSVNLKYTIKAF 71 
WP_014225023   1 MKILILGAGKMGSFFTDLLS---FDHEVAVLEQDPKRMrFIYNAL----RMQ-SVDEiDAFa-PEMVINCVTLTHTLDAF 71 
WP_045090394   1 MRILILGAGKMGSFFADVLS---FDHEVAVLDTDPKKMrFIYNTQ----RMT-DPADvKEFa-PELVINAATLKFTIEAF 71 
WP_013063524   1 MKILVMGAGKMGSFFIDLLS---FDHEVAVFERDAKRMrFTYNCQ----RFT-TYDEiKAFe-PELLINAVTLKYTIPVF 71 
WP_025279522   1 MKIVILGAGKMGSFFADVLS---FDHEVALYDVDPNRLrFAFNTL----RMT-RPEEiGEFa-PDLVINAATVKYTIEAF 71 
WP_012573197   1 MKIQIVGAGKMGAFFADVLS---FDHEVAIFDVDPERLrFTYNCI----RIS-HIEEiAHFk-PEILINAATVQYTVRAF 71 
3GGG_A       112 KKLSYILSEDATVTDQGSVKGKLVYDLEnilgK--RFVGGHPIAGTEKsgveySLDNLYEGKKVILTPTKktDKkRLKLV 189
WP_013446199  72 EKVLPYLPKNCIISDIASVKTGIQAYYEg---TgmRYVSTHPMFGPTF-----ATLDNLSTQSAIIISES--DHmGKAFF 141
WP_005856360  72 KAVMPYLQPYCIISDIASVKTYLKEFYEt---CgfPYVSTHPMFGPTF-----ANLGQLEKENTIIISEG--DHlGKIFF 141
NP_812844     72 RKVLPVLPKDCIISDIASVKTGLKKFYEe---SgfRYVSSHPMFGPTF-----ASLSNLSSENAIIISEG--DHlGKIFF 141
WP_079558014  72 EEVLPYLPDGCILSDIASVKTGFQEFYKq---TgrRFVSTHPMFGPTF-----ANLKDLSAHHAIIITES--DHmGKAFF 141
WP_014225023  72 RSVLPHLRPYCIISDIASVKTNLLEFYKd---CgfPYVSTHPMFGPTF-----ANLGNLMQENAIIISEG--DHlGKIFF 141
WP_045090394  72 NNVLEYLPKNCILSDIASVKTGLEEFYKk---CdhPYVSTHPMFGPTF-----ASLSDLSTQSAIIITES--SHlGKVFF 141
WP_013063524  72 KEVIPYLPKECIISDIASVKTDLKDFYEq---TgmRFVSTHPMFGPTF-----ANLQQLSEENAIIIQEG--DCmGRCFF 141
WP_025279522  72 ESVLPYLPDRTILSDIASVKTGLPEFYAr---AghPFVSTHPMFGPTF-----ANLSDLSTQHVIIITEG--DHlGKVFF 141
WP_012573197  72 EQILPYLTDSCIISDIASVKTGLKEFYEn---SghPFVSTHPMFGPTF-----ANLSNLSSENAIIISES--GHlGKVFF 141
3GGG_A       190 KRVWEDVGGVVEYMSPELHDYVFGVVSHLPHAVAFALVDTLIHmstpevdlFKYPGGGFKD----FTRIAKSDPIMWRDI 265
WP_013446199 142 KDLYGSLKLRIFEYSFDEHDETIAYSLSIPFASTLVFASVMVP--------QEAPGTTFKRhmdiAKGLLSEDDYLLTEI 213
WP_005856360 142 KDIYSSLRLHICEYTFEEHDKVVAYSLGIPFASTMVFAATMKH--------QDAPGTTFKRhmkiARGLLSEDDFLLTEI 213
NP_812844    142 KDLYQTLRLNIFEYTFDEHDETVAYSLSIPFVSTFVFAAVMKH--------QEAPGTTFKKhmaiAKGLLSEDDYLLQEI 213
WP_079558014 142 KDFFGSLGLNIHQYSFDEHDETIAYSLSIPFSSTLVFAACMKK--------QDAPGTTFRKhmdiAKGLLSEDDYLLTEI 213
WP_014225023 142 KDLYEKLKLNIFEYTFEEHDKVVAYSLGIPFASTFVFVATMVH--------QDAPGTTFRRhmkiARGVLSEDDYLLTEI 213
WP_045090394 142 RDLYKGLKLNVFEYTFKQHDETIAYSLSIPFASTLVFASVMKH--------QDAPGTTFKRhmniAQGLLSEDDFLLTEI 213
WP_013063524 142 KELYRKLGLNIYEYTFEEHDKTVAYSLSIPFVSTFVFAAVMKH--------QDAPGTTFKRhmriAKGVLNEDDYLLQEI 213
WP_025279522 142 KDIYQRLRLNIFEYSFREHDETIAYSLSIPFTSTLVFASIMKH--------QEAPGTTFKKhmeiARGLLSEDDYLLTEI 213
WP_012573197 142 RNLYNSLKLNICEYSFEEHDKTVAYSLSIPFASTLIFTSVMKR--------QEAPGTTFRKhmdiAHRLLSEDDYLLTEI 213
3GGG_A       266 FLeNKENvMKAIEGFEKSLNHLKELIVREAEEELVEYLKEVKIKR 310
WP_013446199 214 LF-NPYT-HNQVEKIRAELKTLLEIIDDKDTERMQDFLKMVRKNI 256
WP_005856360 214 LF-NPRT-PRQIERIQEELHILQEIIKDKDSEKMKEYLTKIRKNI 256
NP_812844    214 LF-NPRT-PGQVANIRTELKNLLEIIEKKDAEGMKAYLTKIREKI 256
WP_079558014 214 LF-NPYT-IGQVEQIRKELKELLELIGKRDSDGMQKFLGKVRKNL 256
WP_014225023 214 LF-NPRT-PGQIDRIQRELDELQKIIAERDTEAMRGYLARLRKKS 256
WP_045090394 214 LF-NPYT-SGQVEQIREKLKELIDIIDNKDSQRMKSFLTEVRKNI 256
WP_013063524 214 LF-NPYT-HDQVAQIRTELKELLEIIDQKDAAGMKGYLTKIRNNV 256
WP_025279522 214 LF-NPNT-PQQVKQIQKQMSALLDIIEHKDTDRMKAYLTRVRKNI 256
WP_012573197 214 LF-NPHT-SKQLERIQKKLSFLFQIIENKDVQAMKTFLNEVRGRL 256
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