Conserved Protein Domain Family
DUF6194

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pfam19694: DUF6194 
Family of unknown function (DUF6194)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001597) is described by MIBiG as an example of the following biosynthetic class, polyketide. It includes a member from the fluvirucin B2 biosynthetic gene cluster from Actinomadura fulva subsp. indica. This family appears to be predominantly found in bacteria.
Statistics
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PSSM-Id: 466148
Aligned: 151 rows
Threshold Bit Score: 139.284
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
PJJ55188                  1 MS------------MghrgaelkgvermdidaaqtnrDRLLETIR-SFDGILELapgeggEFPRLAWGDFFFYYAPDGVI 67 
OQO90668                  1 MN------------L----------------------NTVVRHLVdTFDATTTV----------EHEGDTFFYYAPDGRP 36 
EID54348                  1 MNsvapvtpvapvtA----------------------ESVVRHIAeSFDGVHVV----------EHDGDTFCFYGPGGDV 48 
WP_010310471              1 MD------------A----------------------TAMTRYIEeNFDGVRAV----------ENSGDKFFSYDPDGDL 36  Sacc...
SDW06664                  1 ME------------A----------------------TAAKRYIEeTFDGVRAV----------EHAGDTFFAHDPDGDL 36 
SEF92089                  1 MD------------A----------------------AAMTRHITeTFDRIQAV----------ESSGDTFFSYDAPGD- 35 
PRJNA326530:BAY61_14430   1 MNdaw-----------------------------kgpDAARRYIAaTLPGVVAE------NGEGDSAGDTFFSFCPDGVL 45 
WP_067998822              1 MN------------A----------------------DEIKQHIAtKFDGLRVA----------DHLGDTFFIYDPDGDL 36  Noca...
RJO77090                  1 MK------------A----------------------DQVRTYIVeRFPDLMVA----------ENFGDIFFIYDPHGDL 36 
KXK60777                  1 ME------------I----------------------SEISRYVGdTFAGVRAV----------EAAGDTFFLYDPDGDL 36 
PJJ55188                 68 PT-AVQPYATIVTKDypD-DRLSELD-PaGRWRVNIHVGSASFTELVGESPRDVGARGldapgRDFSEPDVFLPHPVYGS 144
OQO90668                 37 DIaRTMPFATIITGD--DtDTVSRLDsP-GAFRLNIGLTKATYVSLLGPAPTRRDDRGvldtgVDYAARDVLLPHPFYAS 113
EID54348                 49 DIaRTLPFATVVTGD--HhEAVSRLDaD-GAYRLNIGLTKASYVERFGPAPTERDEDGvlvtdADYTARDVLMPHPFYAS 125
WP_010310471             37 PDdRWFPFATIVTGD--NyDSVSDLSrQ-GAYRINIGLTKSAYTERFGAAPTRRDGRGvldtgFDYSVRDQVVPHPHYAS 113 Sacc...
SDW06664                 37 PDdRWLPFATIVTGD--HyDAVSDLDhP-GAYRINIGLTKDSYVERFGPAPTTRDESGvlvteFDYAARDQVMPHPHYAS 113
SEF92089                 36 ---QWLLFATVVTGD--TyDSVSRLSrA-GAYRLNIGLTKATYVSRFGPAPTLRDEHGvletgFDHAVPDVVMPHPHYAS 109
PRJNA326530:BAY61_14430  46 RKdRWTPFATIVTGD--TyDSVSGLSeE-GAYRLNIGLPKAVYTGRFGAPPAERDAEGvldtgWDYSVRDAVMPHPHYAS 122
WP_067998822             37 PPqWQMPFATIVTAD--NyDRVSALSdP-DSYRLNIGLTRNRYTELFGPAPSRRDADGvydtgSDYAARDLLMPHPSYAA 113 Noca...
RJO77090                 37 PPkRQMPFATIVVGD--TyDSTSALAtD-GAFRLNIGLTKDTYLSLFGPVPTIRDENGvyatdYDYTVRDQLMPHPIYAG 113
KXK60777                 37 PPqRQQPFATIVTTD--RyDSASRLDaP-GRYRLNVGLTRAGYTGLFGPVPTRRDAAGlpatgPDATVPDRIVPHPVYAG 113
PJJ55188                145 LGWIAVVNPGARTMAAIVELLRAAHEQERRRVIRRAQ 181
OQO90668                114 QYWVCVVEPSEATLRRVHDLLVEAHGFAVRRHENRAA 150
EID54348                126 QYWVGVVNPSASTFDTVRPLLAGAYEFAVRKYDNRTA 162
WP_010310471            114 QHWVCVVNPGPETTDAVRGMLDDAYDFAVRKHENQQA 150 Saccharopolyspora spinosa
SDW06664                114 QYWVCVVNPGPGTADEVRRLLDEAHRFAARKHVNRKA 150
SEF92089                110 QYWVCVVNPAAGTLDDVRVLLDEAYRFAARKHANRSA 146
PRJNA326530:BAY61_14430 123 QYWVCVVNPGPETWADIRELLDEAYRFAERKHANTVA 159
WP_067998822            114 QNWVCVVNPGAATLDTALALVDEAYAFAVRKYANRQA 150 Nocardia pseudobrasiliensis
RJO77090                114 QHWACVVAPGVETFEALTPLLAEAYGFAARKDANWRA 150
KXK60777                114 QHWVCVVNP-DATWPTVRDLLAEAYGFAVRRHANHRA 149
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