6GAU,4I3H


Conserved Protein Domain Family
GyrB

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COG0187: GyrB 
DNA gyrase/topoisomerase IV, subunit B [Replication, recombination and repair]
Statistics
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PSSM-Id: 439957
Aligned: 659 rows
Threshold Bit Score: 751.475
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6GAU_A          8 KAQDE--YGAASITILEGLEAVRKRPGMYIGS--TGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGR 83  
WP_103081602    5 VKNTG--YGNDSISSLKGADRVRLRPAVIFGS--DGIEGCQHSVFEILSNSIDEAREGYGNVIEVVRYKDKSISVRDEGR 80  
BAN02110        2 NTTNT--YEADQIQALSGLSHVRARPLMYLGSagVGVAGLHHLIWEIVDNSVDEAMAGHGDRIEATLHRDGSVSVTDNGR 79  
WP_014261906    4 EKKQNvdYGNNSISSLKGPDRVRLRPAVIFGS--DGIEGCQHAMFEILSNAIDEAREGNGTKINVIRHSDFSVTIEDFGR 81  
WP_012993333    2 ARQQQ--YDNASISSLKGAERVRLRPGVIFGS--DSLEGCEHAFFEILSNSIDEAREGYGDVINVHRYADNSIEVEDFGR 77  
WP_013657385    1 mREKT--YDNQSISALKGADRVRLRPGVIFGS--DGIEGCQHSVFEILANSIDEFKEGYGHTIKVTLHADHSITIEDFGR 76  
WP_003512494    7 NKAER--YGNTSIKSLKGAERVRLRPAVIFGS--DGIEGCQHSFFEILSNSIDEAREGFGKVIEVTRFKDRSIMVKDYGR 82  
WP_012064213    4 KKKQE--YGNESISSLTEIEKVRLRPQVIFGS--DGITGSRHTVDETVANSVDEAKEGFGKLIKVKRFKDRSISVQDFAR 79  
WP_015924898    5 DRKNE--YGNESISSLKGADRVRLRPGVIFGS--DGLDGCEHSFFEILSNSIDEAREGHGNIIEITRFADNSIMVQDWGR 80  
WP_069974271    2 VKKHN--YDNESLSTLVEKDKVRLRPGVIFGS--DGLEGCQHTLMEIVGNSRDEACEGWGNVIEVTRFKDHSIEVKDEGR 77  
6GAU_A         84 GIPVATH---A-SGIPTVDVVMTQLHAGGKFDS---DAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEK--- 153 
WP_103081602   81 GIPLDFN---PkEQRYNWELVFCELYAGGKYKNnsgENYEFSLGLNGLGSCATQYSSEYMDVTVYRDGYRYDLHFEK--- 154 
BAN02110       80 GVPVGKMgdgPhKGRSALEVVLCETNAGGKFDS---DSYKVSGGLHGVGASVVTALSSKVTAEVRRDGHVHRLVLEAtad 156 
WP_014261906   82 GAPLDFN---EkENRYNYELIFEELYAGGKYNTnqgKNYEYSLGLNGLGCCATQYSSEYMDVKVKRDGYLYQVHFEK--- 155 
WP_012993333   78 GIPLDFN---PkENRYNWELVYCELYAGGKYNTnngENYEFSLGLNGLGACATQYASEYFDVQVMRDGYKYSLHFEK--- 151 
WP_013657385   77 GIPVDYN---EaEARYNWELVFCELYAGGKYNNnegDNYEFSLGLNGLGSCATQYSSEFMDVEVKRDGYIYNLHFEK--- 150 
WP_003512494   83 GIPLDYN---EnEKRYNWELVFCELYAGGKYKNnsgENYEFSLGLNGLGSCATQYSSEYMDVTVFRDGMRYDLHFEK--- 156 
WP_012064213   80 GIPVEFN---SkENKYNWELVFCTLYAGGKYNTnsgESYEYSKGLNGLGTTATQFASEYMDVLVRRDGYEYTLRFEK--- 153 
WP_015924898   81 GLPVDYN---SkEERFNWELVYCELYAGGKYQNnsgENYEYSLGLNGLGACATQYSSEYFDVTVFRDGYRYDLHFEK--- 154 
WP_069974271   78 GIPLEWN---PkEQKYNWEIVFTILYGGGKYDNnsgNNYQFSIGLNGLGTAATQFASEYMDVTVFRDEYKYELHFAK--- 151 
6GAU_A        154 -------SEPLG-LK----QGA-PT--KKTGSTVRFWADPAVF--------ETTEYDFETVARRLQEMAFLNKGLTINLT 210 
WP_103081602  155 -------GENIGgLK----KVKcDY--ETTGTFIKWRPDLEVF--------TDIDIPLEYFQNTLKKQAVVNAGIIFKLH 213 
BAN02110      157 engvvepGVAVEpIH----TVK-KCpkSDTGTMIRFWPDLSLFhdenggsfDEPQWSMRIIADRFRHKSFVHPGVTFAVV 231 
WP_014261906  156 -------GYSIGgLK----KEKdSS--PGTYTKIKFKPDTEVF--------TDINITLEFYCDTLKRQAVINKGVSFHLF 214 
WP_012993333  152 -------GENVGgLS----KEPtRF--KRTGTIQHFLPDREVF--------TDIAIPTEYFTETLKRQAVVNNGVHFNFI 210 
WP_013657385  151 -------GENIGgLR----KTKaEY--KQTGSKIHWKPDHDVF--------TDVNVSSEYFYDVLKRQAVVNKNLEFIFT 209 
WP_003512494  157 -------GENVGgLK----KQKwDY--ESTGTIIKWRPDLEVF--------TDINIPLEYYTEVLRKQAVVNAGLKFILY 215 
WP_012064213  154 -------GENIGgLQ----KKKcDY--ESTGTTITWKPDLDVF--------TDINIPLEFYQELLKRQAIVNKGITFELY 212 
WP_015924898  155 -------GENIGgLK----KEKcKY--DRTSTIQKWRPDIDVF--------TDIDIPLEYYQTVLKKQAVVNAGLKFILK 213 
WP_069974271  152 -------GDNVTgTEegfiKTKcGY--EHSGTIIKWKPDLAVF--------NDINIPLDFFKTSLKRQAIVNKGITFKLY 214 
6GAU_A        211 DERvtqdevvdevvsdvAEapKSAseraaestaphkvksrTFHYPGGLVDFVKHI-NRTKnAIHsSIVDFSGKG------ 283 
WP_103081602  214 DEE--------------TG--TDY----------------EYCYQNGIVDYIKEI-NQDK-GFT-EIQFYESSArgrdre 258 
BAN02110      232 DDR--------------EGakEQF----------------EWCSNGGVADLVAEM-TEDTgLVA-PVVSFQGED------ 273 
WP_014261906  215 DEI--------------SN--SEF----------------SYCYENGIVDYVNEL-IGDN-YIS-SPHSVSLETkgrdre 259 
WP_012993333  211 DDI--------------TG--EKY----------------EFFYADGVRDYINELdAGRG-MLQ-NPIYFTASGqgqdra 256 
WP_013657385  210 DEI--------------SN--EKH----------------VYLYEDGILGYAKEV-AEEK-NFT-DVVFTEQETkgkdre 254 
WP_003512494  216 DEE--------------SD--RVF----------------EYCYENGIVDYIKEV-SGDK-AFT-DIQYYETSTrgrdre 260 
WP_012064213  213 DEA--------------SE--ENF----------------TYYYEKGIVDYIEEI-NGGK-ELS-SVQYIELETkgrdra 257 
WP_015924898  214 DEE--------------SG--ETY----------------IYMYENGIVDYIKEI-TKDT-GFT-EVQFYEGSArgrdra 258 
WP_069974271  215 DEE--------------SG--ETF----------------TYLYENGIKDHIRQL-SGEK-GFT-ELQYFELETkgrdre 259 
6GAU_A        284 T----GHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVI 359 
WP_103081602  259 DkpeyKVKMQIAFCFNNE-INLLEYYHNSSFLEYGGAPDKAVKNAFVTEIDKCLKARGKYNKDEAKITFADIQDSLILVT 337 
BAN02110      274 G----DITLDAAIAWTVDGRDTSIGFANGVATPEGGTHINGFRTAVTESVQKYLVERDMLKDKEAPPNTRDIFAAGLMVA 349 
WP_014261906  260 DkpfyKLKADICFAFSNE-ANRLEFYHNSSYLEHGGSPEKATKSAFVSAVDSYIKKLGKYYKNEKKISFSDIEDSLLLVI 338 
WP_012993333  257 DkpmyKVKATVALTFNNE-INGMEYYHNSSFLEHGGSPDKAVRSAITGEFDRQAKNMNKYKANESKLTFNDIQDSLLIII 335 
WP_013657385  255 DrpeyKLKFQVAFCFCNE-KNMLEYYHNSSYLEYGGSPDKAIKNAFVYAIDQYLKNENLYNKDEKKITFVDIQDSLILIS 333 
WP_003512494  261 DkpeyKLKMQIAFCFNNE-VNLLEYYHNSSFLEYGGAPDKAVKNAFVYVIDKFLKSQGKYNKDESRITFQDIQDSLILVS 339 
WP_012064213  258 DkpeyKVKAEVAFAFNNH-ASHIEYYHNSSYLEYGGAPDKAVKSAFLSAIEQYLKNNNLYKKDEKRAIFADIEDSLVLIS 336 
WP_015924898  259 DkpeyKVKMQIAFCFNNH-TNLLEYYHNSSFLEYGGAPDKAVKNAMIYEIDKSIKARGKYNKDESKITFADIEDSLILVV 337 
WP_069974271  260 DkpeyKVKLEIAFCFNNE-VNLLEYYHNSSFLEYGGSPDKAVRNAFVYALDQKLQKEGKYNKDEKKITFQDIGDSLLLIA 338 
6GAU_A        360 SVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVR---RKSATD- 435 
WP_103081602  338 NSFSTITSYENQTKKSITNKFIQEAMTDFLKQQLEVYFIENKVESEKILEQVLVNKRSRETAEKTRVNIKk-kLSGSLD- 415 
BAN02110      350 SVMLPGPQFAGNSKSKLMNPEATSRTRAIVMPAMSRWLEENPEPAKKIADLAIASMRSRTKSNAEQAAVRallGKGNKS- 428 
WP_014261906  339 NSFSTMTSYENQTKKAITNKFIQQALTDFLKEQLEIYFTENQQEGEKIIDQILVNKHSRESAEKTRMAIKr-nLKTTFD- 416 
WP_012993333  336 SSFSTSTSYENQTKKAINNKFIQDFLTEQLRSNLEIWFIERREEAERVLEQVLINKRSRENAEKQRLSIKk-kLMGSVD- 413 
WP_013657385  334 NSFSTVTSYENQTKKAITNKFIQEAIQEYLKEFLYIYFIENKDAAMLIAKQVLVNKRSREKAERTRINVRk-qLSGSID- 411 
WP_003512494  340 NSFSTITSYENQTKKSITNKFIQEAMTEFLKEKLEVYFIENKVECTKILEQVLVNKRSRETAEKTRVNIKk-kLSGNVD- 417 
WP_012064213  337 NSYSTLTSFENQTKRAISNVFIQSALTDFLKEKLQIYFIENKVEADKIANQIIINKRSRESAEKTRINVKk-kLESPSN- 414 
WP_015924898  338 NSFSTITSYENQTKKSITNKFIQETMTDFLKQQLEIYFIENKIESDKIIEQILVNKRSRETAEKTRINIKk-kLSGNLD- 415 
WP_069974271  339 NTYSTITSYENQTKKAITNVFIKDVMTDFLKEKLEIYFIENKLETEKILEQVLINKRSREKAEKTRIDVRk-qLSKKIDn 417 
6GAU_A        436 IGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIH 515 
WP_103081602  416 ISNRVKKFVDCRTKDVSRREIYIVEGDSALGSCKLGRDAEFQAIIPVRGKILNCLKAEYDSIFKNEIIVDLLRVLGCGVE 495 
BAN02110      429 RNGLPAKLRDCTFKTDRPTELLLVEGESAGGTAIDARDPSFQAILPLRGKPLNSYRESISRVVKS--MADLILSMGCGIG 506 
WP_014261906  417 PLTRIKKFVDCRTKNPDERELYIVEGDSALGSCKQGRNSDFQAIIPIRGKILNCLKSDSARIFANDIITDIISILGTGVE 496 
WP_012993333  414 ITNRIKKFVDCRTKDLNRRELYIVEGDSALGSCKLGRDAEFQAIIAVRGKILNCLKADLATIFKSEIITNLIKVLGCGVE 493 
WP_013657385  412 IGNRIKKFVDCRTKDVTRRELYIVEGDSALGSCKLGRDSEFQGIMPVRGKILNCLKADYDKIFKSDIIIDLLKVLGCGIE 491 
WP_003512494  418 ISNRVKKFVDCRSKDVNKREIYIVEGDSALGSCKLARDAEFQAIIPVRGKILNCLKADYDSIFKNEIIVDLLKVLGCGVE 497 
WP_012064213  415 FANKVAKFVDCKTKDKSKRELYIVEGDSAMGSTKQGRDSEFQAIMPVRGKILNCLKAKLDNIFNDSVIVDLLKVLSCGIE 494 
WP_015924898  416 ISNRVKKFVDCRTKDISRREIYIVEGDSALGACKLGRDAEFQAIMPVRGKILNCLKAQYDNIFKNEIIIDLLKVLGCGVE 495 
WP_069974271  418 ISNRVKKFVDCRSKDKNKRELFIVEGDSALGSTKMGRDAEFQAIMPVRGKILNCLKSDYDKIFKNDIIMDLLKVIGCGVE 497 
6GAU_A        516 ---------DEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLK-W----------- 574 
WP_103081602  496 iktkhnkefNTFDINNLRWDKVIICTDADVDGFQIRTLILAMLYRLVPTLIKAGKVYIAESPLFEIT-T----------- 563 
BAN02110      507 ---------DDFDLDKFRYDRIVVLADADDDGLHIRALILAFLYTWCPGLVESGRLFYALPPLWTTV-H----------- 565 
WP_014261906  497 mnskhlkdiADFNMDNLRWNKIIICTDADVDGFQIRTLLLTMFYMLTPTLIEKGYIYIAESPLYEIS-S----------- 564 
WP_012993333  494 ikskqnkelTAFDLNALRWDKIIICTDADVDGYQIRTLILTMFYRLLPTLLAEGRVYIAESPLFEIV-Atk--------- 563 
WP_013657385  492 itskhnkdlHTFELDNLRWNKVIICTDADVDGYQIRTLILTMLYALVPTLIKEGRVFIAETPLYEIN-T----------- 559 
WP_003512494  498 ikskhnrelSTFDLNNLRWSKIIICTDADVDGYQIRTLILAMLYRLVPTLIQVGKVFIAESPLFEIR-T----------- 565 
WP_012064213  495 iksknntdlYTFELDKLNWDKVIICTDADVDGYQIRTLILAMLYRLVPTLLREGKVYIAETPLFEII-Sttlpkltdkqk 573 
WP_015924898  496 ikskhnkdlNTFDLANLRWDKVIICTDADVDGFQIRTLILTMLYRLVPTLLSVGKVFIAESPLFEIT-C----------- 563 
WP_069974271  498 vrsrhlkdlTDFDLSNMSWNKLIICTDADVDGFQIRCLIITMLYVLTPTLIEEGYVYIAESPLYEISdE----------- 566 
6GAU_A        575 -----------QRsDPEFAYSDRERDGLLEAgLkA-GKKINkedgIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDA 642 
WP_103081602  564 -----------KN-KTYFAYSEKEKNQILSK-IsG---KYT----IQRSKGLGENDPDMMWETTMNPETRRLIKVMPDDV 623 
BAN02110      566 -----------RG-ERIYLEDDAAMREWRAD---NpTHKAH----MGRLKGLGEMDADELRSVMG--NDRKIGMVDIDDP 624 
WP_014261906  565 -----------KN-KTYFAYSEKEKEAILSK-IkG---SYH----VQRSKGLGENEPDMMWETTMNPETRRLIQVTEYNP 624 
WP_012993333  564 ---------grKE-VTHFAYNEKEKAEIIRN-LaG--YRLN----IQRSKGLGENEPEMMWETTMNPQTRRLIQVMPESE 626 
WP_013657385  560 -----------KD-KVYFAYSEYEKTEILSK-Ik---TKYT----IQRSKGLGENDPDMMWETTMCPESRRLIQVMPDNM 619 
WP_003512494  566 -----------KD-KTYFAYTDKEKNEIVSK-LkG---KYT----ILRSKGLGENDPDMMWQTTMNPETRRLIQVVPDDI 625 
WP_012064213  574 dgitfvenkgdKN-YSIFVYSDQQRDFVVSK-LkG---KYA----IQRSKGLGENEPEMMWQTTMNPQTRKLIQVTMSDA 644 
WP_015924898  564 -----------KN-KSYFAYTEKEKAEILAK-LeG--KKYT----IQRSKGLGENEPEMMWETTMNPATRRLIKVMPSDV 624 
WP_069974271  567 -----------KG-HSYFAYTEGEKAQILKK-IkG---KFK----IQRSKGLGENEPEMMWETTMNPDSRKLVQVTPAEA 626 
6GAU_A        643 AAADELFSILMGEDVDARRSFITRNAKD-VRFLDV 676 
WP_103081602  624 VRTEQVFDLLLGDNLQGRKEFIEENGYRyMDMIDV 658 
BAN02110      625 ARLARLAERLFGSKSELRRTWYLERSGE-S--LTV 656 
WP_014261906  625 EDTKIAFDTLLGDDLQSRKEYIENFGHLyLEQVDE 659 
WP_012993333  627 DTMQAKFDLLLGDNLTGRKEHIENNGHLyLDQLDI 661 
WP_013657385  620 EDTQTMFDVLLGDDLKGRKQFIADEGYRyLDLADM 654 
WP_003512494  626 KKTEEFFDLFLGDNLPGRKSYIEEHGHKyLDMIDV 660 
WP_012064213  645 QKADDVFDLLLGNNLEGRKVHIAENGHKyLEQIDV 679 
WP_015924898  625 EKTTMMFDVLLGDNLAGRKQFIEDNGNKyLDMIDV 659 
WP_069974271  627 KATQEAFELFLGDNLPGRKQFIEEHGHKyLDISDV 661 
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