4FW3


Conserved Protein Domain Family
LpxC

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COG0774: LpxC 
UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell wall/membrane/envelope biogenesis]
UDP-3-O-acyl-N-acetylglucosamine deacetylase is part of the Pathway/BioSystem: Lipid A biosynthesis
Statistics
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PSSM-Id: 440537
Aligned: 483 rows
Threshold Bit Score: 213.35
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4FW3_A         5 IKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLV-KG-DVKVDTVEHL 82 
NP_875809      9 EGAWTLGGAVRRRGVCLHSGQESEVTLLPYD-DIGFHLSWVNRSEKP-VRLNSNQVVHSELCTTLD-LA-FERLATVEHL 84 
NP_682580     13 TTQRTLAGTAQWSGVGLHSGQWVALTLQPAAANTGRQFVRLDLEGQPVIPARIEAVKSTQLATELV-AN-GASVRTVEHL 90 
NP_924811      1 MQQQTLAATVQLSGISLHKGASVAVRLCPAPPDSGRCFVRADLAGTPAIPALARGFRPSPLCTTLS-EN-GAAIQTVEHV 78 
WP_011130780   9 DRAWTLGGAVSRQGIGLHGGEVAEVRLQPSA-QVGFHVSWLDNSDSP-VTLGPHQVRDSQLCTTLE-LG-DRHLGTVEHL 84 
WP_011242925   5 IPRRTLAGPVDCAGVGLHSGAEVNVRLEPAVSGRDRIFVRTDLPGTPEIPVQLDRVRETLLSTELA-TD-QANIRTVEHL 82 
WP_014806208   3 MKRVTLQRPIEVEGLGLHSGKIGKVVMLPSDGGDGIMIGAVK--GQMPYPIGKCDIFSPGRSTCVVlPN-GHTIFTMEHL 79 
WP_015110629   9 RQAWTLRSSVERSGVGLHSGAVSRVRLGPSE-RPGYWLGWLDAPELPMQRLGPTQVSDTRLCTCLQ-VG-ERRLATVEHL 85 
WP_082726392  55 VRQVTIARPVEFEGKGIHSGQWSRVRLEPARSGGGIRFVRADLPGRPVIPTEPGRVVGTRRSTTLG-IG-EARVQTVEHL 132
WP_108614755   4 AQQYTLAQAISQSGVGLHSGEITTVKILPATRG-GRHFVRVDLPECPIITASCESVRSTTLSTELG-NSdSASIRTVEHL 81 
4FW3_A        83 LSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKK-FIRIKR---EVSVEE--GDKRAVFVPF---- 152
NP_875809     85 LAALVGCGLTHVHIVVSGNEVPLLDGSAMGWVEAISEVGMIPLKDSSSlWPVLKN---ALVIHK--GTSVITATPS---- 155
NP_682580     91 LAALAIAGIDNVTIQITGPEVPVLDGSAQPWLEGIQRVGVVPQEAPRP-AVILKE---PVTIYE--GEAFVSAIPA---- 160
NP_924811     79 LAALYGLGIDNCRIEVEGPELPILDGSARPYVEAVVRSGTVRQNAPRR-FYQIAE---PVAVYE--RDAFVVAMPT---- 148
WP_011130780  85 LAALAGCGLTHVEIQVGGEEIPLLDGSALGWVEAIAEVGLTPAATPRAdPLVLEH---ALVCHR--GSSVITATPA---- 155
WP_011242925  83 LAVLAGLGVTDVQIAIDGPELPLLDGSGAEWLAAIAAVGTVELLGAVS-VPVLTE---PLTVSE--GDAFVTAVPA---- 152
WP_014806208  80 LAALYGMGVDDIIVLVDGDEIPIFDGSAGQWVKLLEETGLREREGTEKtIYSVCS---PLCVEDesGDAWVACLPC---- 152
WP_015110629  86 LAALAGTGVSQAELWVEGEEIPLLDGSGLPWVEAIAEAGLSDRGERLE-PPLPPL---PLTLGQ--GLGFVAALPS---- 155
WP_082726392 133 LASLAGMGVWHADVLVWGEELPAGDGSLTTFTQMLEEAGRQEIEPDGR-AVPVRSvpvPVLVEE--GEATLVALPPvhgd 209
WP_108614755  82 LSALTAGGVSHARIEVNGPELPLLDGSAKPWSEAIAAAGLKEIEPQP--SAPLNQ---EISVRQ--GDAFVMAIPS---- 150
4FW3_A       153 D--GFKVSFEIDFDHPVFrgRTQQASVdFS-----STSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRV 225
NP_875809    156 D--RVTLIGIIDFPYPAI--GKQMFSLdLT-----PQSFLQDIAPARTFGFKDQIDHLREKGMIKGGGLDNSLVCDGKSW 226
NP_682580    161 P--ELRLTYGIDFPYRAI--GRQWCSFtPS-------ELATEVAPARTFGFAEQVDYLRSQGLIQGGSLENALVCSASGW 229
NP_924811    149 DtpALQVSYGIDFPHP-I--GRHWFSLeLT-----PENFAREVAPARTFTLQSQVEQLLACGLIQGGSLDCALVAGADDW 220
WP_011130780 156 E--RFNVVGVIDFPQAAI--GHQMLAIeLT-----PEGFTEQIAPARTFGFREQVDQLLAAGLIQGGALDNALVCDGDHW 226
WP_011242925 153 E--ETRLSYGIDFDLAPI--GNQWFSVrWR-----PDDWEREVVPARTFGLAPQIEALRQQGLIRGGSLENALVCDRDRW 223
WP_014806208 153 E--NLKVTYVISFDDVSI--GTQTFVAeVT-----RTRFVEEIAPSRTFVRLKDVEELKKEGLARGGSLHNALVFGNDGL 223
WP_015110629 156 E--RLRLAAAIEFPQAAI--GRQLYALdLT-----PERFVAEIAPARTFGFREQVEQLLAAGLIRGGALDNALVCDGDDW 226
WP_082726392 210 E--GLTLRYVFLSQHRGL--ASQQFRFaVQpgaedAATFAREVAPARTVAFLSEVEALRREGLAMGEP-GMAVLVGEEKV 284
WP_108614755 151 T--ETRFTYGIDFEVAAI--GNQWHSWsPD-----EQNFITEIAPARTFTLASQIEALQKAGLIKGGSLDNAIICSHSGW 221
4FW3_A       226 LNEdGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADK-D 282
NP_875809    227 INP-PLRFKDEPVRHKLLDLIGDLALVGLP-KAQVLVYKGSHALHVELAKSISREC-S 281
NP_682580    230 VNP-PLRFADEPVRHKLLDLWGDLALLGTPPIAHYVAYRASHHLHTQLARAIAQQR-V 285
NP_924811    221 LTP--PTWPDEPARHKLLDLLGDLSLAGVALSGHIVAYKAGHALHGRLARALAEKV-P 275
WP_011130780 227 LNP-PLRFADEPVRHKLLDLIGDLALVGFP-QAQVLVYRGSHGLHNDLANALLAVC-P 281
WP_011242925 224 LNP-PLRFSNEPVRHKLLDLAGDLSLLGALPQAHILAYKASHRLHVRFARELQARM-A 279
WP_014806208 224 LNDtQMRFANECARHKALDLLGDLALVGLPLQAHVIGYKAGHRLHLRLVDRLRRLCkG 281
WP_015110629 227 LNP-PLRFADEPVRHKLLDLLGDLALVGLP-RAHVFAYRGSHGLHTAMAAALAAQA-P 281
WP_082726392 285 LTA--LRFPNEVARHKLADLLGDLAVLG-PLAGTVIGVASGHALNQRLTQALSSVF-Q 338
WP_108614755 222 INP-PLRFANEPARHKILDLVGDLSLLGTIPLAHYLAYKAGHHLHVELVRRISQTP-T 277
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