2EOC


Conserved Protein Domain Family
WGR
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pfam05406: WGR 
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WGR domain
This domain is found in a variety of polyA polymerases as well as the E. coli molybdate metabolism regulator Swiss:P33345 and other proteins of unknown function. I have called this domain WGR after the most conserved central motif of the domain. The domain is found in isolation in proteins such as Swiss:Q9JN21 and is between 70 and 80 residues in length. I propose that this may be a nucleic acid binding domain.
Links
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Statistics
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PSSM-Id: 398851
Aligned: 106 rows
Threshold Bit Score: 45.3102
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2EOC_A          35 CTLNQTNieNNNNKFYIIQLlqdsnRFFTCWNRWGRVGEV--GQSKINHFTRLEDAKKDFEKKFREKTKNNWAER-DHFV 111 human
Q981N7           8 LWIERRDadRNMARFYALSIeetlfGQTCLVRRWGRRNHRphGTALLRYRGRSHRAFPRASARQADARLSAAIRL-PDAQ 86  Mesorhizobium...
Q3JF56          13 AYLEKRNpeKRQFRFYRIMItqtlfGSWAMIREWGRIGSP--GTVREVWFDSEQEALEAGEKLMNQKTRRGYQVIt---- 86  Nitrosococcus...
jgi:Dshi_3754    9 VDLERIDpaRNMARFYRLSVqptlfGEQSVIRSWGRIGTQ--GRSMMVTYASEGDAVKACKKLLCSKVARGYLCL-NDVE 85 
Q877R6           9 LHLRRIDttRNMRRFYLLSIqptlfGGVSLIRDWGRIGTT--GQTMVQTFDASAEAGEAFGRLERAKRRRGYTSA-EERV 85  Bradyrhizobiu...
jgi:Xaut_4993   33 LHLRRIDpaRNMRRFYTLAIqptlfGGATVIRNWGRIGTN--GQSMMETFDQPEQAERAFSRLARTKRRRGYGDAgVNGN 110
Q98P43           9 AHLHRIDgaRNMARFYSLTIqptlfGGASLVRNWGRIGTK--GQIKIETFDEPQDVDCAFTRLERAKRRRGYVDP-GNTV 85  Mesorhizobium...
Q9R6F6           9 VHLHRIDaaQNMRRYYRIAIqptlfGGASVVRNWGRIGSG--GQTMMETFDHPDDADTALFLIERTKRRRGYRDA-GSSQ 85  Agrobacterium...
Q1QEX3           9 LHLRRIDpaRNMRRFYLLSIqptlfGGVSLIRNWGRIGTN--GQTMMQTFDDSTDAGDALGRLERAKRRRGYGDA-SAER 85  Nitrobacter h...
jgi:BBta_p0010  21 LHLRRIDaaRNMRRFYALSTqptlfGEMSLIRNWGRIGTS--GKIMVQTFDGSAKAVEAFERLERAKRRRGY-AV-ADGN 96
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