146304662 3 FPENMVKVEIISPVNQKDKVTTEILKFGKMEVIEPAHPIsnSRYEDARRELTAIQEHVNKVKLIMEIagtpleprg--km 80 15921722 3 IPETMARVEILTPKQKINELITALLKFKEFEPEEPKTPIsnLRFEDARRNLGEVNEHINKMKILMELggliiepqg--km 80 238620009 3 LPENMVRLQIISDKSAVDPIVTKLLKLGMFQPEDPLYPLsnERIEDARRLITAVQDHVSKLKIIMELgglvieplg--si 80 227827836 3 LPENMVRLQIISDKSAVDPIVTKLLKLGMFQPEDPLYPLsnERIEDARRLITAVQDHVSKLKIIMELgglvieplg--si 80 229585106 3 LPENMVRLQIISDKSAVDPIVTKLLKLGMFQPEDPLYPLsnERIEDARRLITAVQDHVSKLKIIMELgglvieplg--si 80 70607281 1 ----MVRAEIITTKDNVNEVVSKLLKLGTFEPDDPKVPIsqNRLEDARRILGEINDKIARLILLMEAseiavepkgnlkq 76 15897481 3 LPENMVRLQIISDKSAIDPIITKLLKLGMFQPEDPLYPLgnERIEDARRLITAVQDHVSKLKIIMELgglvieplg--si 80 124027665 7 VAQATVEVIVGVPRGEYARTVKALAESSVFHPEPLEGIV----AHEVRRLRNELEAVAERLRQAATVagvaaggea--vv 80 156937402 8 FPDRMFKVRVVVPKDSADKLVEKIVNLGSYEPAEAKVEFg-APIEWARRDLLVIMDHINKLEQYFEFfelsvepemgepv 86 118431146 3 LPRMLEEVVLAVPARDYDRVVAGLAVEGIFHVDSPPQGVkgEVDRSYRALLTQASERSSRIRQYFDLagvepyrvsgvei 82
146304662 81 kvdstwTDvAKKLSEEASLEEFRYKELLEEIGKLKGEIDLYQAQLRELEPFSGITTDLSTLYSLE--TLDVALVVLTEDQ 158 15921722 81 kvndwiEA-SNQVFIEGSEIENKYKDLLEEIGKLRAELDTLNSQLQEVEPFKNIGIDLKVLYSST--NFEVALVVINEIQ 157 238620009 81 kvvnwiKA-AQDVSEEASKLEERYKELLEEIGRLRAEKDLYQQQLKELEPIKSITVELSKLYSLE--LFDVILAQVSEDK 157 227827836 81 kvvnwiKA-AQDVSEEASKLEERYKELLEEIGRLRAEKDLYQQQLKELEPIKSITVELSKLYSLE--LFDVILAQVSEDK 157 229585106 81 kvvnwiKA-AQDVSEEASKLEERYKELLEEIGRLRAEKDLYQQQLKELEPIKSITVELSKLYSLE--LFDVILAQVSEDK 157 70607281 77 dkqdwiEI-ARIYTSEASKIEEKYRELLEEIQKLKSERDSLKLKLDELEPFKDVDIDLKKIYANT--YFDVALAILNRQQ 153 15897481 81 kvsswiKA-AQDVSEEASKLEERYKELLEEIGRLRSEKDLYQQQLKELEPIKSITVELSKLYSLE--LFDVILAQVDEDK 157 124027665 81 riksssDAgLSELLRELSTLASSVSELVEKLAQLQNPESELSKKLRILQYYAFIDVDLERLTRSR--HVRAKVYRIPLGF 158 156937402 87 kvksweEA-AKVAAERAKKIEDEFEKYTSRIKEIEAKMFDVS-------------------------TLISKPAELPKDV 140 118431146 83 evggwgES-WKRYLEKYSGVEKFYSGLLEEYSEAEARLKELLDIEARIAPVAHLDVDIARLYRSGafDFAVYYGSYSEGL 161
146304662 159 LN------KVKSNKNVVVETTPLKDGKYASVLISRRNVVSLDQVLKELGVRRFETne--------gKSPYEVYKVLSERI 224 15921722 158 KK-------QLEDKGAVVIVEELGNNKYASLVLSRKGSNL-DEILKELGLRKFETpd--------fIAPQIYYSNLKERI 221 238620009 158 LRli---sQIIGDSGFAYYTRFEEGKYTVLIITEKN--ADIEKKLKETGVRRYELqe--------gKSPFQLYNEISERI 224 227827836 158 LRli---sQIIGDSGFAYYTRFEEGKYTVLIITEKN--ADIEKKLKETGVRRYELqe--------gKSPFQLYNEISERI 224 229585106 158 LRli---sQIIGDSGFAYYTRFEEGKYTVLIITEKN--ADIEKKLKETGVRRYELqe--------gKSPFQLYNEISERI 224 70607281 154 IE-------ELKKRGFEVISYQSNNFYPSLIIGLKG--TGLNETLKELGIKRLETqd--------lVSPSQQYKTIMDRI 216 15897481 158 LRli---nQIIGDSNFVYYTRFGEERYIVLIIAEKN--INVDKKLREAGVRRYELqe--------gKSPFQLYNEILERI 224 124027665 159 AEefiaelSRVEGVVVAYTDGIEPGYMTIVVVYPARLETEVGKVALRHRAEPLEIped------wpRIPARAVERARREL 232 156937402 141 VE---------------------KLKETFNLIISREIPAELRKDLAVVDLAAKEAl----------KISTEIVRKVALEL 189 118431146 162 ESrv---gEIVSRVGGLAAVEASGGSVVVAVAVPKGALSKISPEILR---LNLSIytppegvpgspREAMEYIRGEKARL 235
146304662 225 G-ELRKILEETRSSLIKKIRenerefselygkllTARDALSLLSKGRISDHFFQIEGYVPERDWKKLKSALDQVA----- 298 15921722 222 N-NIQTILTQRREELAKKIKedeknvkelygkllTIRDAMNILAKARKSEYYVQVEGYVPDKSLKKLSKMIENIG----- 295 238620009 225 N-QINTILERTREELAKKVKteenyiknvygkllTVRDALNIMNKARISEYYLQIEGYLPEKYVKRVQNEMKDLA----- 298 227827836 225 N-QINTILERTREELAKKVKteenyiknvygkllTVRDALNIMNKARISEYYLQIEGYLPEKYVKRVQNEMKDLA----- 298 229585106 225 N-QINTILERTREELAKKVKteenyiknvygkllTVRDALNIMNKARISEYYLQIEGYLPEKYVKRVQNEMKDLA----- 298 70607281 217 N-YIDGVLGAKRKELREKANedkewiqstygkllTLRDSMLVLSKAKISDYFIQIEGYVLEKSTKQLTNSLKDSA----- 290 15897481 225 N-QINIILERTREELAKKVKteenyiknvygkllTVRDALNIMNKARVSEYYLQIEGYFPEKHVKKVQNEINNLA----- 298 124027665 233 E-ELPRRIGEYRPQILRALTav-----------eAAVKLLRLLEATKFTRTAAFIHGYVDPSQLDRLEEQLQDIGvkg-f 299 156937402 190 LrLLEEEKKFLIEEAKAWASdyeieisntyalllSVKNALEVLSKGRESDYFVYLEGYVPESFFKNTLKALKDYVasvgf 269 118431146 236 GrRLVSIQEMASERLGELAEfyt--------vvtAFENIFKFLVSTLRRGETRIVRGFVDVRDSGRLRSIVDRMTrg--s 305
146304662 299 -VIESATPrrfgEE---------EEPPTYIR-LPKSISAIESVVEIYGTPSYWEISPLVFLVITFPLLFGLMFPDVGNAL 367 15921722 296 -FITYEYPkrygEEq--------EEPPTYVK-LPKSIIPLESVIEFYGTPSYWEISPTIFLIITFPFLFGLMFPDFGNAL 365 238620009 299 -HVDYIRPrrygEK---------EEPPTLVE-LPKSIKVLESLVEIYGSPSYWEISPIVFLVFTFPILFGLMFPDFGNAL 367 227827836 299 -HVDYIRPrrygEK---------EEPPTLVE-LPKSIKVLESLVEIYGSPSYWEISPIVFLVFTFPILFGLMFPDFGNAL 367 229585106 299 -HVDYIRPrrygEK---------EEPPTLVE-LPKSIKVLESLVEIYGSPSYWEISPIVFLVFTFPILFGLMFPDFGNAL 367 70607281 291 -VVVYEYPkrfgEQ---------EEPPTYVN-LPKSIRPLESIIELYGTPSYWEISPTLFLIITFPLIFGLMFPDLGNAI 359 15897481 299 -FMDYIRPrrygEK---------EEPPTLVE-LPKSIKVLESLVEIYGSPSYWEISPIVFLVFTFPILFGLMFPDFGNAL 367 124027665 300 vILVREEShrhgKPghgeeeheaKRTPSFYR-VTKLLAPFADLLSMSGHPRPGEVVPVVLMAITLPVIYGLMFPDLGHGL 378 156937402 270 aLVHMVDYd-------------sEKPPTYVKvESQSAKTAYDVENIYGPPDPREFVPAAIMAFTLPFIYMFMFPDWGHAL 336 118431146 306 yVLLSLGVrrggEA----------PIPSKVD-LPQFLKPFSRVVELYGYPEPNEIVPTVFLAITLPLTFALMFPDAGQGL 374
146304662 368 VLLI--FAIfFHRYGVKKGS----------------NNIKNLSLILGYSSVVAMITGFLARDFFGPLPVGGLKemgianv 429 15921722 366 VLLL--FSIwFYNYGKKRGS----------------ENTVKLSLVLIYSSIVAMVTGLLAREFFGPLPVGGLQellnnps 427 238620009 368 VLLL--FSIwFYRYGKKRGS----------------ENIPKLSIILIYSSIVAMITGLLARDFFGPLPVGGLReilnngn 429 227827836 368 VLLL--FSIwFYRYGKKRGS----------------ENIPKLSIILIYSSIVAMITGLLARDFFGPLPVGGLReilnngn 429 229585106 368 VLLL--FSIwFYRYGKKRGS----------------ENIPKLSIILIYSSIVAMITGLLARDFFGPLPVGGLReilnngn 429 70607281 360 ILLI--FAVwFHNYGKKRNS----------------ESIRYLSLVLIYSSIIAAITGILAREFFGPLAVGGLRellnnps 421 15897481 368 VLLL--FSIwFYRYGKKRGS----------------ENIPKLSIILIYSSIVAIITGLLARDFFGPLPVGGLReilnngn 429 124027665 379 VLLLagYYL-------FYKR----------------MGNVNLGRLVMYFGIAAMVTGFLAGEFFGPHPVVAGWlsegiwh 435 156937402 337 VLVLfgWGL-------VNRKgwalavfrpfglrrftRGTEFLGRIMMLVGTASIITGWLSAEFFGPLIGESAvdpamwlw 409 118431146 375 LVLL--FSL-------FYLR----------------RVSRDWAYVIAVMGGASVVSGLLAGEVFGPLVSKMLGlpelwyr 429
146304662 430 sgpldsvwp--vpvsvtealspllpfGEYSTSTSIEHT---------IILSILLGAIALFVSSLLGVINAVKKRdpeflV 498 15921722 428 apvgplyyawpipvsfyekisdiiptGANAIINT-------------ILLSLLLGSILLFVSTLLGVINAIKKKdkeflF 494 238620009 430 ysagplynlwpipasvseaikfllpfGEYSTSVSIENT---------MIFSVLLGAIALFVSSLLGIIDAIRKKdseflF 500 227827836 430 ysagplynlwpipasvseaikfllpfGEYSTSVSIENT---------MIFSVLLGAIALFVSSLLGIIDAIRKKdseflF 500 229585106 430 ysagplynlwpipasvseaikfllpfGEYSTSVSIENT---------MIFSVLLGAIALFVSSLLGIIDAIRKKdseflF 500 70607281 422 ypvgplyniwpisesvyekiapilptSGETGIVNT------------IIISLLLGSILLFVSSILGVINTIKKKdyeylV 489 15897481 430 ysagplynlwpipasvseaikfllpfGEYSTSVSIENT---------MIFSVLLGALALFVSSLLGVIDAIRKKdpeflF 500 124027665 436 ghpp-----------lasplhefvtkPAEEAAEAAVPLlf-----naIYLSLLIGALVMTVSSLISIVNGVLlgd-revL 498 156937402 410 -------------------galgmapPLSFGLEHLGDTvi-----kyVLLSITIGYFHLLIGFLIGILNELRFGrpwkaL 465 118431146 430 l-----------------gletppyaMPTYAIDHGEEElvpvlvyraLNVSLFMGAFMLSFGTFLGVVNGVIKRdwvglV 492
146304662 499 FEKLPLLVLYTVPLVIFGYGVtdpshyfstvgvllgdilqnllsgihpdlsnptSALAYGLIVWVEIGLIYNWISKAIIL 578 15921722 495 LDRLPLFIIYIVPLIVFLYGFinisnyqgeeamilgg-isyflfhsgtpappsvQILADILVIWVEIGLIYNWVAKAYLL 573 238620009 501 LEKLPLFLLYVVPIFIFMYGItdpanffivdqril-----gqilnavlmkslseNIIGYGIVWWTSFALLYNWVAHAILV 575 227827836 501 LEKLPLFLLYVVPIFIFMYGItdpanffivdqril-----gqilnavlmkslseNIIGYGIVWWTSFALLYNWVAHAILV 575 229585106 501 LEKLPLFLLYVVPIFIFMYGItdpanffivdqril-----gqilnavlmkslseNIIGYGIVWWTSFALLYNWVAHAILV 575 70607281 490 LDRLPLLLIYTPPLIVFSYGFtnisnytlqiqellgg-ieyfifhsgspapgttQILATSLVIWVELALIYNWIGKIIIL 568 15897481 501 LEKLPLFLLYVVPIFIFMYGItdpanfftvdqqil-----gqilnavlmksfseNIVGYGIVWWTSFALLYNWAAHAILV 575 124027665 499 VASIGKTLIFGSILLALTLGAaagagaavler------------aagiladagmSLVPETTLGMVVRLLFSIGLLTVLVA 566 156937402 466 HYVFPFMLMYATAGAPFAAGFiasgfgsdieqmmy-----ltglyfnewmfnlkTGHIGPLFVLFVIALLWRGYGIKLEL 540 118431146 493 ESRLPRFLLFASITGPFLVYMdageag----------------------svlrqALLELGGDSIAAKLVLAGSVLGLAWM 550
146304662 579 KRHDHASTGSALamg------fiEGGFEAAIlLLSNTISFIRILVFALAHYYLLYAFSYMAYLVVGHps-lLALGTNPAS 651 15921722 574 KKHEHASTGSAIifg------fiEGGFEAALlLLSNTISFIRVLVFAIAHYYILYAFSYMAYLAAGNpsslLSVFINPAG 647 238620009 576 KRHDNATWGSAIamg------fiEGGFEGALlLLSNTISFIRVLVFALSHYYILYAFSYMAYLVAPStt-tIGVLLNPIA 648 227827836 576 KRHDNATWGSAIamg------fiEGGFEGALlLLSNTISFIRVLVFALSHYYILYAFSYMAYLVAPStt-tIGVLLNPIA 648 229585106 576 KRHDNATWGSAIamg------fiEGGFEGALlLLSNTISFIRVLVFALSHYYILYAFSYMAYLVAPStt-tIGVLLNPIA 648 70607281 569 RKHEKVSIGNAIvtg------fiEGAFEAGIlLLSNVISFIRILIFAIAHYYILFAFSFMGYLAAGSpnslLAVFINPAS 642 15897481 576 KRHDNATWGSAIamg------fiEGGFEGALlLLSNTISFIRVLVFALSHYYILYAFSYMAYLVAPStt-tIGVLINPIA 648 124027665 567 PIVFGHGGLGEKiin------glMEAFDMLLmAIGNTASFMRIMGLMLAHSGLMFGFTILAMVAGPV-----------LG 629 156937402 541 EHEHGRAQASIVg----------MEMFDNFLlVISNIISYVRIMALALAHWGLVFAFQVIGEIGGPV-----------LL 599 118431146 551 LLAGPIIYMLEGhsplaglansfLEAYESLLmLVGNIPSFLRIMALALAHSSLMFVIYYLTVMIMQG-----GILADVVG 625
146304662 652 IVILIIGNLLAIGLEGLVVFIQDMRLHFYEMFSKFYEGRGKKFEPLVASVE 702 15921722 648 IVILIIGNLLAIALEGLIVFIQDMRLHFYEMFSKFYEGRGRKFEPVMTYVE 698 238620009 649 IVILIIGNLLAIGLEGLVVFIQDLRLHFYEMFSKFYEGRGRKFEPVMAYVS 699 227827836 649 IVILIIGNLLAIGLEGLVVFIQDLRLHFYEMFSKFYEGRGRKFEPVMAYVS 699 229585106 649 IVILIIGNLLAIGLEGLVVFIQDLRLHFYEMFSKFYEGRGRKFEPVMAYVS 699 70607281 643 IAIIIVGNLLAIALEGLVVFIQDMRLHFYEMFSKFYEGRGRKFNPVKTYVE 693 15897481 649 IIILIIGNLLAIGLEGLVVFIQDLRLHFYEMFSKFYEGRGRKFEPVMAYVS 699 124027665 630 AITYIFGNILTIGLEALVAYAHSLRLHLYEMFSKFYLDEGRPYQPLQLPAT 680 156937402 600 AILYVLANIMVIMLEGLVSFIHNLRLHFYEWFTKFYIDRGKLFEPAVQYTK 650 118431146 626 ALLYVGGNLAVAAMEGLLAFAHASRLHFYEWFSKFYSGTGVPYTPIKVEGV 676