Conserved Protein Domain Family
DUF2188

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pfam09954: DUF2188 
Uncharacterized protein conserved in bacteria (DUF2188)
This domain represents a ribosome-associating protein predicted to mediate translation inhibition alongside repair of DNA damage or restriction in conflict contexts. A subset of this family contains a conserved histidine residue, raising the possibility that it directly acts as a RNase or in RNA end-processing.
Statistics
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PSSM-Id: 378323
Aligned: 99 rows
Threshold Bit Score: 34.9578
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_008735328    8 YHVS--PssEHAAaag-vkWQVEGREGRRLlHEPHRTQKDAIDGARRHA-KE----HqPAQVIVHAR-D-GHIRSAYTY 76  Streptomyces
WP_010025636    6 YQVV--P--HDNG------WAYKLGDTL---SETYATADEAIVRAKDAA-SRqkigDgDALLAYPSP-DgGWAFQELET 69  Rhizobium
KPH08790        6 YEVV--P--HDGG------WAYRLGGVY---SEAFPTHAEALEAARIVA-AEqqvgGdSAEISWQDE-N-GKWHEEYAE 68 
Q1YJW9         74 YYVLk----DGDG------WKVRHNDKDTP----YDTQAEAMEAARDAA-HKmhdsGtDSQVLVQGS-D-GQWQTEWTY 135 Aurantimonas ma...
CAN91649        7 YHVM--PdpDGWG------WVVAAEGYVTR-SLPYGTMQEAIESTEELV-RQ----HpGSALVIDEQ-PpPLTPIEIEH 70 
jgi:Slin_0755   4 WLYNlhPiiM---------WTVNHFPAAMR-SLNPSTRAKAIEVANRLLeQGqldgQrVVAISIEEArRwARLEASHAE 72 
WP_008239232   13 GEII--P------------WSKGDYPSSYK-NQPKYLREKAVEIANEVL-KEsgdkGiAIATGLKKArEyFKHHPEETK 75  Pedobacter sp. ...
jgi:Tmel_1092   5 YFVE--WnsNNQK------WQLKQEKGSKA-IKNFDTKAKAIIYSRNVA-KN----NaPSQLVIKKK-N-GKIEKEWTY 67 
WP_012242473  130 YHVS--Qn-KDEKsefknqWRVRKQGSQKT-IKYFKTQAEAIAFAETLA-EN----N-DTSIVIHKR-D-GSIRKQ-DY 195 Acholeplasma la...
Q8EVE5         26 YYLS--ArkDKDGkk--egWEVKMENCERI-SALVATKEEAIEKAKSLA-GK----K-SATIIIRRL-D-GSIQDTIKY 91  Mycoplasma pene...
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