Q57880 1 MDYYVTLSPGLEKISKNEIESFG-------GKIKEIRENKGRIFFSGDLK------------LIPKINYLSRTIERMNIL 61 Methanocaldo... WP_012819593 1 MDYYSTLSPGLEKVSQREIETLG-------GKIREIRNNKGRIFFKGDLE------------VIPKINYLSRTIERLNIL 61 Methanocaldo... WP_004590774 1 MKFYSTLSPGLEDIAANELESLG-------AKILEKREGKGRIFLEGNLE------------LIAKINYFSRTIERLNIL 61 Methanocaldo... WP_013100419 1 MELYSTLSPGLEKIAKEEIESLG-------GKVKEIREERGRVFFEGDLK------------VMAKLNYFSRTLERINIL 61 Methanocaldo... 1_ncbifamImport 1 FKYYATLPPGLEKISSDEIEELG-------GRIFRIKEGKGRIFFEGDFE------------LIPKVNYLSRTIERTIIL 61 WP_012940841 1 MRIYATTTPGLEDVSANEIELLG-------GKVEEVRFGKGRVFLTGDLE------------LVAKLNYLARTLERVMIL 61 Archaeoglobu... WP_013413732 1 MKFYVTFPPGLEEVVKQELQNCYk------VKIEK--AERGRVYFRGSEK------------LIPDLNYWGRYWERVVWL 60 Methanotherm... WP_125743047 1 MEFYATCTPGLEFISAKEIEGKGl------GRLIELREGRGRVIFESEYD------------MIPSLNCSLRSVERIVLL 62 Candidatus K... WP_012966032 1 MIFYSTTAPGLEDVAAEELKELGc-------RIKEERKGKGRVFFEAEIE------------DIPKLNCFSRCSERIVLL 61 Ferroglobus ... Q8U248 2 KFLLTTAQGIEDIAKREVSLLLKklgisfqIEEKPLGIEGRLLLEAEKAYyvdekgrkrelsISTYLNENSRLLHRVIIE 81 Pyrococcus f... WP_112093978 1 MEVYATTHKGLERITAEEIQELG-------GKIEK--YGNGRVYFKCDER------------LIKKLNYHARTCERIIVL 59 Methanotherm... 2_ncbifamImport 1 DVFYATCPPGLEFVAAGEIEGKRl------GRVVEIREGKGRVFFRSSWQ------------NVPRLNCLLRSVERIVFL 62
Q57880 62 LHREEIPNi-------ALDDIYKRVYNIDWTeWIKENQSFAIRPLRAGEHNFTSIDIGRVAGEAVIKSYQRDKNIRLKVN 134 Methanocaldo... WP_012819593 62 LHREEIPNi-------SLEDIYERVYSIDWSeWIKEDQAFAIRPLRVGTHNFTSIDIGRVAGEALINSYKRDKNVRLKVN 134 Methanocaldo... WP_004590774 62 LHREVLEDi-------SLDEIYKRVYEINWEdWIKEEQSFAVRPLRVGEHNFTSIDIGRVAGEAVIKRYLSEKGVRLKVN 134 Methanocaldo... WP_013100419 62 LYRGEVE---------SLEDIYEVIYNLDWT-FIDENKSFAIRPLRVGSHNFTSIDIGRVAGEALIKSYLRDKNVRLKVN 131 Methanocaldo... 1_ncbifamImport 62 LKLEEFENi-------TLDDIYKSVYEIDWTeWIREEQAFAIRPLRAGEHDFTSIDVGRVAGQAVIDAYKNAKGVRLKVN 134 WP_012940841 62 LRVEKFEK---------LDDIYRIVKEIDFS-FIKPNQSFAIRPLRVGNHDFTSLDVGRVAGQAVIDSYMESGGVRLKVN 131 Archaeoglobu... WP_013413732 61 LHKDEVKD---------LEEIYKKVRSIDFS-FIKPNQSFAIRSKRFGEHDFTSMDIARVAGQAVIDSYLSSKNKRLEVN 130 Methanotherm... WP_125743047 63 LARERTSE---------LDGIYRAVKGIDFS-FMRPEWSFAVRSNRLGEHDFTSVDIGRVAGQAVIDSYMEARGVRLKVN 132 Candidatus K... WP_012966032 62 LGRFKVEK---------LEDVYKAVKSIDFS-FIKPEQSFAIRANRVGEHGFTSIDIAREAGQAVIDRYKEDFGVRLRVN 131 Ferroglobus ... Q8U248 82 IASEKFNGiekdeseeALKRIKDFVSSLPVEqFVKVSETFAVRSFRKGDHNITSIDIARTVGEAIFERLSRFG--TPLVN 159 Pyrococcus f... WP_112093978 60 LKSAKITQ---------LEDIYKEVKDIDFS-FIRPSESFAVRSKRVGVHDFNSMDIARVAGDAIIKSYQSSRKKRLKVN 129 Methanotherm... 2_ncbifamImport 63 LGRERAEG---------LEDIYRIVRSIDFS-FIRPEWSFAVRATRVGEHDFTSIDIGRVAGKAVIDSYIEEKGVRLRVN 132
Q57880 135 LDEPDVIVRVEVIFDELIVGIDTTGDIALDKRGYRVFNHPAHLNATIASSLVYLSDWKDDEMLLDPMCGSGTIPIEGALM 214 Methanocaldo... WP_012819593 135 LNEPDIIVRVEVIFDEVIVGLDTTGDIALDKRGYRVFNHPAHLNATIASSLIYLSDWKDEETLLDPMCGSGTIPIEGALI 214 Methanocaldo... WP_004590774 135 LDEPDIIVRVELIFNELLVAIDTTGDEGLHKRGYRVYNHPAHLNATIAASLIYLSGWKDEEFLLDPMCGSGTIPIEGALI 214 Methanocaldo... WP_013100419 132 LDEPDVIVRVELIHNELLVGLDTTGDIALDKRGYRVYNHLAHLNSTIAASLIYLGNFREYESLLDPMCGSATILIEGALI 211 Methanocaldo... 1_ncbifamImport 135 LDNPDVIIRVDVIFNELIIGIDTTGDEGLHRRGYRAYNHPAHLNASIASALVKLSNWKDDEILLDPMCGSGTILVEAAMI 214 WP_012940841 132 LDEPDVIIRVDVINDEVYVGLDTTGDIALHRRGYRVYDHPAPLNPAIASALVMLSGWKCDEILLDPMCGSGTILIESAMM 211 Archaeoglobu... WP_013413732 131 LDEPDVIVRVELIDNLLLVGIDTTGDDGLHKRGYRIYQHPAPLNPVIAASMVKISSWKINETLVDPMCGSGTILVEAAFI 210 Methanotherm... WP_125743047 133 LDSPDVIVRCDLIKDELLVGIDMTGDEGLHKRNYRVYQHPAPLNPTLASSLIYLSEWSHEHSLLDPFCGSGTILFEAGMI 212 Candidatus K... WP_012966032 132 LDEPDVIIRCDLVDDDFVVGVDTTGDEALHKRNYRIYQHPAPLNPTIASSLVRLSGWSHNYSLLDPMCGSGTILIEAGMI 211 Ferroglobus ... Q8U248 160 LDHPAVIFRAELIKDVFFLGIDTTGDSSLHKRPWRVYDHPAHLKASIANAMIELAELDGG-SVLDPMCGSGTILIELALR 238 Pyrococcus f... WP_112093978 130 LDSPDNIIRVELIHDLLLVGVDTTGDKGLHRRGYRVYQHPAPLNPTIAAALLRISNWRPEKILVDPMCGSGTILVEAALM 209 Methanotherm... 2_ncbifamImport 133 LDEPDVIVRCDLIDDDFMVGIETTGDEGLHRRRYRVYQHPAPLNPVLAASLVYLSGWSSTKSLLDPFCGSGTILFEAGMI 212
Q57880 215 KRNIPPGKFRENkygFKFIDIFGYELLDKIKKEIVenkniYKIIGLDKNQKYLDGAKDNAKNAEVLDTIEFICGDATKLH 294 Methanocaldo... WP_012819593 215 KRNIPPGKFREKkygFKFVNIFGYGLLEEIKKSILeneelYSIYGIDKNEKYILGAVENARSAGVFDTISLSIGDATKME 294 Methanocaldo... WP_004590774 215 KRNIPIGKFRERrygFSFVKIFGHELLDKIKNCYNenyrsYKIVGMDINSEYLEGAKKNAINANVIDTVKFLNGSAEELD 294 Methanocaldo... WP_013100419 212 RRNIPPGIFRERkygFSFLNLFGRELLEDVKREVNinyekYLIYGIDKNPKFLEGAKRNLESAMVDDTVNLILGDATKID 291 Methanocaldo... 1_ncbifamImport 215 KRNIPPGKFRDD---FAFIKIFGREALDEIKSQIVenkkmLKLYGVEKFKKHISGAVKNAENVGVVDTIKFIEGDATELE 291 WP_012940841 212 GRNIPPQKLRDD---FQFVKIWGKEILEDVKKYVTesdvdLNLVGIERFRKHLKGAKINSEVAGVADTIDYVQGDATKLC 288 Archaeoglobu... WP_013413732 211 GKNIPPGHLR-D---FAYKKLFDMEPTQKKIREVD-----LNLIGIEKFKKHVEGCKKIVKNLGLD--IKIFQGEAERMH 279 Methanotherm... WP_125743047 213 ARGTPVCKFRRD---FAFLKFFG-ELPSFEERDVE-----LKLYGVEKFRKHIEGAELIARYVGIY--PEFIQGHAERIG 281 Candidatus K... WP_012966032 212 AKNIPVCKFREN---YAYKKLFKLPEPEWEEKDVE-----LKLYGMEKFKKHVEGARKIAEYVGIP--VTYIQGDARKLD 281 Ferroglobus ... Q8U248 239 RYSG-------------------------------------EIIGIEKYRKHLIGAEMNALAAGVLDKIKFIQGDATQLS 281 Pyrococcus f... WP_112093978 210 GSNIPPGRIR-E---GG-KLTFNHK---------------LKIIGIEKFRKHVKGCQETLSRLGIDF-IKVIQGDAEHLD 268 Methanotherm... 2_ncbifamImport 213 ARQIPICRFRKD---FAFTRFFD-SLPEVEEKDVE-----LRLYGIERFRKHLEGARTIADYTGIH--PVFLEGLAERIE 281
Q57880 295 EKF---NESDVIIANPPYGIRIGSKRSVKKLYDEFLSSAKEIMHGSSRLIVITAEDKMFKDAIAKNNFEVKEEFNVMFGG 371 Methanocaldo... WP_012819593 295 ENF---KDIDVIIANPPYGIRMGSKRGVKKLYEKFLLSAKKIMHDSSRMVVITAEDKLFREAVVRQNFNIMDEFAVMFGG 371 Methanocaldo... WP_004590774 295 KFF---NSLDVIVTNPPYGIRMGKKRLIGKLYNNFLSSAKNLMHGDSRIVVITAESKLFKDAVIKNNFNIIKHFDVMFGG 371 Methanocaldo... WP_013100419 292 KIF---NEVDLVVVNPPYGIRLGKKRLLRELYNNFLLSVKRVMHGNSRVICITAETKLFEEAIAKADLTVKEKFNVKFGG 368 Methanocaldo... 1_ncbifamImport 292 KIDylkDGVDVVITNPPYGIRIGGKKMVRNLYNNFLNSLKKITHDDSRIIIITAEDKILRNAAINNNYKIKEEFRVMYGG 371 WP_012940841 289 LKT-----ADVVVTNPPYGLRIARKGMIEELYEGFLRSAKGIVD---RIVVITAEYRILKEKAEALGYVIEEERLVKYGG 360 Archaeoglobu... WP_013413732 280 EYV---ENVDVIVTNPPYGLRIGRKYITKKLYKDFLKEAYNILPSHGRIVFITPMKRFMRKIANKIGYDINKEIKIEYGK 356 Methanotherm... WP_125743047 282 KYF---DSVDFIVTNPPYGLRIGKKGIIEKIYAGFLRAASSILKKR--MVVITSETSIFEKHARDN-FEKIEKLEVMYGG 355 Candidatus K... WP_012966032 282 EYF---DSIDFIVTNPPYGLRIARKGIIEDLYSKFLESASKVLEKK--LVMITAEKNIARHYAEKF-FEIKEERNVMYGG 355 Ferroglobus ... Q8U248 282 QYV---DSVDFAISNLPYGLKIGKKSMIPDLYMKFFNELAKVLEKRG--VFITTEKKAIEEAIAENGFEIIHHRVIGHGG 356 Pyrococcus f... WP_112093978 269 KYV---QEADLIVTNPPYGIRVGRKSIIKKLYHNLLRTAKNILTENGSITLLTPQEKILKSTATKLDYKWT-ETPIVYGN 344 Methanotherm... 2_ncbifamImport 282 EHL---ERVDFIITNPPYGLRIGKKKIIEDLYSGFLHSASKVLEEK--AVVITAEREIFERYAEEC-FPDFLRYDVKYGG 355
Q57880 372 LMTRVFYLT 380 Methanocaldococcus jannaschii DSM 2661 WP_012819593 372 LLTKVFIIS 380 Methanocaldococcus vulcanius WP_004590774 372 LLTKVYYIK 380 Methanocaldococcus villosus WP_013100419 369 LSTKVYYLT 377 Methanocaldococcus infernus 1_ncbifamImport 372 LDTVVFVLK 380 WP_012940841 361 LDTKVFVLR 369 Archaeoglobus profundus WP_013413732 357 LPASIFLLK 365 Methanothermus fervidus WP_125743047 356 LRTGVYIVR 364 Candidatus Korarchaeum cryptofilum WP_012966032 356 LNCSVFVLE 364 Ferroglobus placidus Q8U248 357 LMVHLYVVK 365 Pyrococcus furiosus DSM 3638 WP_112093978 345 LPVKIFKLT 353 Methanothermobacter tenebrarum 2_ncbifamImport 356 LLTGVYVLK 364
Jiyao W et al.(2023). "The conserved domain database in 2023.",