Conserved Protein Domain Family
F420_MSMEG_4141
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TIGR03620: F420_MSMEG_4141 
probable F420-dependent oxidoreductase, MSMEG_4141 family
Members of this protein family, related to F420-dependent oxidoreductases within the larger family of a bacterial luciferase (an FMN-dependent enzyme), occurs only within the small subset of species that synthesize F420. Most such proteins are from members of the Actinobacteria, but at least one species, Sphingomonas wittichii, belongs to the Alphaproteobacteria. [Unknown function, Enzymes of unknown specificity]
Links
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Statistics
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PSSM-Id: 274681
Aligned: 15 rows
Threshold Bit Score: 311.612
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_011434535  10 IGKVGIWSGqFDF--SPaav-vrEAVAELDDLGYPTLWTGEVKGRE-VLVTAALALAAtSRMTIATGIAQILARNPLTMT 85  Frankia
WP_011607410   5 VGKFGVWTSiARW--PDdrqaraDAVAELDELGYGAIWLGGAT-AS-LELPEALLDAS-RRLVAATGILNVWTEPAKVVA 79  Frankia alni
WP_003975951  12 VGRYGVWSVqLRAedPEgaaeraEAAAELERLGYGALWLGGNSAA---RHAAPLIRAT-ERIVVGTSIQSIWEHKPSEAA 87  Streptomyces
WP_011607660   5 VGRIGLWAAqRQW--PTdvrsraEVAAEVAAMGIPTVWIGAASGD--LELPAAILDGT-EGLVVGTSILNIWTEKADIVA 79  Frankia alni
WP_011595455  12 FGTHGVWAGwDKF--SP------EQARAIEELGYGTIWLGGSPKH--LRPIRKILDAT-EAITVAAGIVNIWNTDAAVIA 80  Rhodococcus jostii
WP_011723874   3 LTGVGIWSSqLRY---GdpaesaDAAAELDELGFPALWIPDVGGPV-FDAVGHLLGAT-KRTVIATGILNLWMHSPAEVA 77  Mycobacterium a...
WP_011207371  15 LGRFGVWRGyKGF--RP------EEAAELERLGYGALWLGGSPPAA-LPTVEPLLAAT-TTLTVGTSIVNIWTAPAAEVA 84  Nocardia farcinica
WP_011564055  12 gGEVGLWTSiLNH--LPaar-mrEAAALAEELGYGALWFGEAMGREvFASAAILLSAT-GRIKVATGIANIFVRDAWATN 87  Rubrobacter xyl...
WP_011727159  12 PSRIGVWWAsDTW--Smrd--aqEVAREIEALGFGSLFLPETVAKEcLTQSAAFLAAT-ERLVIGTGIANIHVRLPSAAE 86  Mycobacterium s...
WP_011597069   7 LGPVGIt---LNI--SPdet-ylDEAARLESLGYSAIWLRGGQIDS-LDRIPAVVRAT-DSIPVATGIIPVGVYDSDAVA 78  Rhodococcus jostii

WP_011434535  86 AGQLALAEAYPDRFLLGLGVSHAELMhi-rgA-----SYTRPLAQMAAYLDEMD--R------M---AVEQYRavpppgv 148 Frankia
WP_011607410  80 DSYARVSKSHPDRLLIGVGAGHAAFV-----Ge----RYWHPFRAVESYLDRLDlpQ------S---RVPRDA------- 134 Frankia alni
WP_003975951  88 AGFAELEVSHPGRFVLGLGVSHGPRV-----E-----GYRRPYSTMVGYLDELD--R------A---GMRSGH------- 139 Streptomyces
WP_011607660  80 DHYAMLAKAHPDRLLLGFGVGHRGPV-----EkltgrRWERPVEVLLDYLDTLD--E------L---GVPRSD------- 136 Frankia alni
WP_011595455  81 DEFVELEDDFPGRFYLGIGAGHREAI-----A-----GYQKPYTAVNHYLDILD--A------K---KVPTQR------- 132 Rhodococcus jostii
WP_011723874  78 ESYAALTAEHGDRFLLGIGVSHAPLIdagqpG-----RYRKPLAATARFLDGLDgaP------R---PVPIER------- 136 Mycobacterium a...
WP_011207371  85 ESFHRIDARYPGRFLLGIGVGHPEAV-----S-----AYRKPYDALVEYLDDLD--A------A---GVPRER------- 136 Nocardia farcinica
WP_011564055  88 AAAKTLAEAYPGRFVLGLGVSHRPLV-----Evr-ghDYRSPLSRMRSYLGEMR--R------AqfnAVKPERea----- 148 Rubrobacter xyl...
WP_011727159  87 AGARTLTALYPGRFVLGLGVSHGPLVergmgG-----VYQKPLATMRTYLERMA--AlpeqieP---GAGRPP------- 149 Mycobacterium s...
WP_011597069  79 QLFADLQTTAPDRFVVGLGGPQVP----------------RPLRALNEYLDRLDrsD------P---PVPAER------- 126 Rhodococcus jostii

WP_011434535 149 ppRVLAALGPKMLGLARDRADGAHTYFVPPEHTAAARDILGPGKLLVPEQAFVLHTDPEQARELARRHTG-SYLRLPNYT 227 Frankia
WP_011607410 135 --RLLAALGPRMLRLAGERTAGAHPYLVTPEHTWRARDILGLGPLLAPEQKVVLTTDATQARTIARRALA-VSLALPNYT 211 Frankia alni
WP_003975951 140 --RVLAALGPKMLDLSRDRAAGAIPYLVTPEHTAQARERLGEGPLLAPEFKVVLDADPSRARATARAYLA-MYLKLPNYT 216 Streptomyces
WP_011607660 137 --QALAALGPRMLDIAARRSAGALPYLATPEHTRRAREIMGPDALLAPEQKVVLDTDPDSARAVARKGIG-FYLGLPNYA 213 Frankia alni
WP_011595455 133 --RILAALGPRMLRLSADRALGAHPYLTQPTHTALARAELGDGVLLAPEHKVVIDIDPQKARAIGRPPVDqPYLHLTNYV 210 Rhodococcus jostii
WP_011723874 137 --RVLAALGPKMLKLSASRAGGAHPYLVTPDHTASARATLGHGPLLLPEQTVILTDSAEEARRIGTDWLR-AYLALPNYA 213 Mycobacterium a...
WP_011207371 137 --RAVAALGPRVLELARDRAAGALPYLTTPEHTRRARDVLGAASLLAVEQKLVVDDDAERARALGRPVVA-RYLGLRNYV 213 Nocardia farcinica
WP_011564055 149 -pVLIAALGPRMLELARELADGAHPYLVTPEHTGWARGILGRGPLLAVEQGAVLAGDRSEALRLARSHLS-RYLRLPNYR 226 Rubrobacter xyl...
WP_011727159 150 --RLLAALGPKMIELSGTHADGAHPYLVLPEQTRTTREILGEDKWIVSEQAVAVGGDDADQLRRAHQHLE-VYSGLPNYR 226 Mycobacterium s...
WP_011597069 127 --RILAALGPRKLELARDRAAGAVALLVTPDYTAKARRSLGPDATLVVSLMTVLGTDAAQARDTARVPLR-FLSGVGGYA 203 Rhodococcus jostii

WP_011434535 228 TNLRRFGFDDDDLAGSGSDRLVDTIVPWGDADVLLGRIKEHLDAGADQVAVQVLDFD-RRGLPRrqWRELAPVL 300 Frankia
WP_011607410 212 ENLLRLGFVEDDFVGSGSDHLVDSLVAWGSVATIRGRIEQHHNAGADHVAIQVLTAQaDAPLPTaqWRALAEGL 285 Frankia alni
WP_003975951 217 KNFLNLGFTDDDVTGGGSDRLIDAVFAWGDEATIRARIDAFHAAGADHVALQLVTDD-MARLPRegWRRLAALL 289 Streptomyces
WP_011607660 214 NNLRRLGFTEADLAGSGSDRLVDALVAWGDLDTVLARIAEHHQAGADHVAVQVLTPT-PSQLPLdqWGRLAGAI 286 Frankia alni
WP_011595455 211 SNLKRLGWADVDIADGGSDALIDALVAHGDAATVRGQVDKHLTAGADHVAIQVLGE----GDPVgpLAEIVKAa 280 Rhodococcus jostii
WP_011723874 214 NNLLRSGFSEDDLSQV-SDRLFNAIIAWGDEEAVMRRVAEHRSAGADHVCVQVLLAD-PTAFPReeWRRIAAAs 285 Mycobacterium avium
WP_011207371 214 ANLRRLGYSESDVAGQGSDRLVDALAVHGTPAQVADRLRAHRDAGADHVALQPLEDD-----YLapLRALAPLL 282 Nocardia farcinica
WP_011564055 227 NSWLRQGFTEEDLAGEGSDRLVEALVAWGSEEDVRARVREHLEAGADHVCVQVITDR-PERGLDeeWRALAPAL 299 Rubrobacter xylanophilus
WP_011727159 227 NSWLRQGFDESDLVRGGSDRLARAVVGMGSVDDAAKAVTAHLDAGADHVVVQVLGDT-PTSDPRpvLRELAGAF 299 Mycobacterium smegmatis
WP_011597069 204 TNFERMGFGADDISGL-SDRLVDDLVAWGDADAIVARVHSHLAAGADHVAVSELGER-----PGevARQLAGLL 271 Rhodococcus jostii
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