1WJ9


Conserved Protein Domain Family
Cas6_I-E

?
cd09727: Cas6_I-E 
Click on image for an interactive view with Cn3D
CRISPR/Cas system-associated RAMP superfamily protein Cas6e
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family
Statistics
?
PSSM-Id: 187858
Aligned: 50 rows
Threshold Bit Score: 120.876
Created: 23-Nov-2009
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
1WJ9_A         1 MWLTKLVLNPAsraar---------rdlaNPYEMHRTLSKAVSrale------egrERLLWRLEparg--leppVVLVQT 63  Thermus thermop...
Q6NEQ5         5 IHLVKLPVHIAlsvpaknk--prkgweltDPSFRHRAVMALFPdtdsp---lprksVDILFRFEqlag---qppFFLIQS 76  Corynebacterium...
Q47PJ5         2 TWLTKIVPDLRyrqtr---------adfrTAGNLHRKLIRLSSdlgeerianprqqSGLLFRIEetr----nelYLLVQS 68  Thermobifida fu...
Q1EQT0         3 IWLTRIVPDLRsrdarr------dltgtaTAVGLHRRLMALFPqdagp---dpraqFGVLFRIEdtt----tgpHVLLQS 69  Streptomyces ka...
Q825C0         3 VWLTRIVPDPRsrdarr------dlggndSAMGLHRRLMSLYPcdagp---dprarFGVLFRIEdtp----agaHILLQS 69  Streptomyces av...
Q8KB24         1 MIATMLTLSRKdvka----------lritDSYSLHRVIYSLFEdvrseaekrssvpSGFLFADKggda---kgrKILILS 67  Chlorobaculum t...
Q60AD3         5 LYMIELRPDPAalirfaqdqglnthqdqdLGYATHAWLKALCGe-----------lAPKPFRLLqdgrn-lrppRLLGFS 72  Methylococcus c...
Q2RXJ4         4 LYLISLPLDMVsfhrwag----qrgigtdEGRALHHLLGESFG-------------KGVLQPFRlmvapngatgTLYAYT 66  Rhodospirillum ...
YP_001218551   4 LFASALHLDRRavka----------lkitDAYSLHRVVYSLFPdvrspeekgghtqSGIVYADQggdf---hgrKVLVVS 70  Vibrio cholerae...
YP_001536852   3 AWLTRIALDLRhsaar---------rdlrDTTALHRRVMSLVPdglge---qprhhAGVLFRLDhtt----tgpMLLVQT 66  Salinispora are...
1WJ9_A        64 Lt-EPDWSvldeg------------yaqvFPPKPFHpal---kpGQRLRFRLRANPAKRlaatgk--------------- 112 Thermus thermop...
Q6NEQ5        77 Tv-APKQVdnl---------------dseVQHRTVSlrr--fspKSAVRFRISINGIRRqttehngrkritts------- 131 Corynebacterium...
Q47PJ5        69 H--SPLRVdrlgp------------gyhgVQMRNLDpflarldkGSRVRYRIVASPTKRlgrsenntqrlglk------- 127 Thermobifida fu...
Q1EQT0        70 Th-EPDLTrlpd-------------gygtSLSRPLDplldalepGLTVRYRCVASPVRKpgattrevy------------ 123 Streptomyces ka...
Q825C0        70 Ah-EPDLTrlpd-------------gygqAITRPLDplldalkpGLTIRYRCTASPVRKpgantraly------------ 123 Streptomyces av...
Q8KB24        68 D--RPPLQpah----------------geLVSRPVPeef---lqHRFYKFEVTLNPTRKenksgk--------------- 111 Chlorobaculum t...
Q60AD3        73 AhdGTRLTeharafaspl-aaqvcsladgIAFKPMPesw---pnGRKLGFEVMACPISRlgrneddvyrrhl-------- 140 Methylococcus c...
Q2RXJ4        67 R--ADRTAlvqttrdfglpdalavcdparLAAKAMPedw---reGRRLAFDLRARPVRRllkpagvfpkgaevdafllea 141 Rhodospirillum ...
YP_001218551  71 Dr-MPNASvdgv--------------hgeVVSKTISeaf---lhHQTYRFKVQVNPVRKdkqsgk--------------- 117 Vibrio cholerae...
YP_001536852  67 Tl-PPDPNrlpd-------------gyaaVDTRDVSpllkaltnGMAMHYRIAANASKRawkgnsa-------------- 118 Salinispora are...
1WJ9_A       113 --------------rvalktPAEKVAWLERRLEEGGf--RLLEGErgpwvqilqdtflevrrkkdgeeagklLQVQAVLF 176 Thermus thermop...
Q6NEQ5       132 -------pvpfdsdekapshITRMTPWVQKKLNGAL---RNVEILnhqrevigt---------khrggkaasMTIQIDTV 192 Corynebacterium...
Q47PJ5       128 ------eppkkpreytwalrGAAAEEWWHSRAAANGl--ELLSTYaqtlddvrd---------pgtadrsrkIRHPAVRF 190 Thermobifida fu...
Q1EQT0       124 -----------nlpavvplsGAAADEWWLRQADTAGl--KSLTHHaqpldpaqgtr------gphtpgkeqrVRHARTRF 184 Streptomyces ka...
Q825C0       124 -----------nlpavvplnGAAADEWWTRQADAAGl--KPLALHphpldaaqgv--------ragngdkqrIRHNRIRF 182 Streptomyces av...
Q8KB24       112 --------------rvpiktREEVAAWFGGKSQTSW---GFSVDParldvrmlpv-------mqfskqgdrtVTHGAARV 167 Chlorobaculum t...
Q60AD3       141 -------rdcdaraqspdsrEMVYRRWLTRQFGSAAtldDFSLDGfrylrllr-----------kargtrsgFLAPQALF 202 Methylococcus c...
Q2RXJ4       142 lrrfpegrpaegvagapitrEGVYFQWLAERLSGAArveEVRLARferrav---------------lrgsksIEGPDAVF 206 Rhodospirillum ...
YP_001218551 118 --------------riavkgRQDIAQWFIERAAKSWg-fEVHPQHlqidsievq---------qfndkhgrkITLGKAHI 173 Vibrio cholerae...
YP_001536852 119 -------------gkvvalsGQQAEQWWQRKAEATGl--DLRHLRaqpqpaa--------------rgraipVRHAITLF 169 Salinispora are...
1WJ9_A       177 EGRLEVVDPERALATLRRGVGPGKALGLGLLSVAP 211 Thermus thermophilus
Q6NEQ5       193 DGFGIVEDPELLNELILHGVGRAKAYGCGLLSVSE 227 Corynebacterium diphtheriae
Q47PJ5       191 DGEAVISDVDAVRHAVLNGIGRGKSYGCGLLSLAL 225 Thermobifida fusca YX
Q1EQT0       185 DGSAIINDPDLLRQKITEGIGRGKAYGCGLLSIAP 219 Streptomyces kanamyceticus
Q825C0       183 DGSATITDPDLLRQKITEGIGRGKAYGCGLLSIAP 217 Streptomyces avermitilis
Q8KB24       168 SGMLRVENRDLFIESFNKGIGRGRAFGFGLLQIEP 202 Chlorobaculum tepidum
Q60AD3       203 RGTLSVRDGAGFGALLARGIGRHRAFGFGMLLLRP 237 Methylococcus capsulatus
Q2RXJ4       207 HGELVILDGAKFAGHLASGLGRHTAYGYGMMLLRP 241 Rhodospirillum rubrum ATCC 11170
YP_001218551 174 QGQLRVTNEPQFHHSFKHGIGKGRAFGCGLLQIVP 208 Vibrio cholerae O395
YP_001536852 170 EGQAVITDADQVRAAVLAGIGRGRSFGCGLLSLAP 204 Salinispora arenicola CNS-205
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap