Conserved Protein Domain Family
PRK07768

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PRK07768: PRK07768 
long-chain-fatty-acid--CoA ligase; Validated
Statistics
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PSSM-Id: 236091
Aligned: 44 rows
Threshold Bit Score: 667.084
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
300790052   1 MSRFVDTLVATATk-rGQQRGMVTG--------EPKEPVRRTWAEVHEEARRIAGGLVAGGFERGTAVGVLAAAPVLIAP 71 
111225874  17 RASTMVYLLDRMRrasTGPNTVTFL--------APDGGRRVGWAELYGDARRVAAGLQSHGVGPGRPVAILADTSRQTIT 88 
118619948   1 MNTIMRRLCDSQG---ATQHGLTTApvgadgrsHLDQLTNTPWSDIHHLGRRAAGALQRDGVTPGDVVAVLAGAPGEIAP 77 
118619238   1 MSRFTDAIATTAS---NSPRGLHFG--------AAGGLRFASWRDIHQTAVRVAGRLSAEGVTRGSRVTVLAAGPEDVAP 69 
169628782  11 SNPVIDRLLAGAG---ITGRGLTSApigpdgasQLDELSTTAWADVHRTGLRIAGALQAAGVRPGDAVAVLAGAPGEIAP 87 
183980208   1 ----MRRLCDSQG---ATQHGLTTApvgadgrsHLDQLTNTPWSDIHHLGRRAAGALQRDGVTPGDVVAVLAGAPGEIAP 73 
183983262   2 SSRLVREIGAAAE---SSPNALYVG--------SVDAPREITWRAVEEQAHGMSNSLAARGIGRGDTVAVLAAEACDVAP 70 
183984938   1 MSRFTDAIATTAS---NSPRGLHFG--------AAGGLRFASWRDIHQTAVRVAGRLSAEGVTRGSRVTVLAAGPEDVAP 69 
256374801   1 MSRFVDTVVATATgeqGSRRGMTTG--------EPSTPEHRTWAQVHARATRVAGALVEAGVTPGAAVAVLAGDPAEIAP 72 
258654664   1 MSAFSDALCTAAQ----GPTGMTTG--------EPHEPVRTSWADVHAKACAGARVLAAHGIGPGDAVAVLAAKPFEVAP 68 
300790052  72 TVQAVWLAGGSVTMLHQPTPRTDLAEWAEDTVRVLGMIGSDqdalggpgglaprpgsgagprnvTVLLGEPFDQLAPVLE 151
111225874  89 AAMATWLAGGSLTMAPTPARTVDLARYLADTRDRFDALGEP-----------------------LVLVGAPWEDAVPALS 145
118619948  78 LVQGAWMCGAAVTMLHQPTHRSDLQAWAADTKKTLSMVGAS-----------------------TAVVGSPFQSAAQEFA 134
118619238  70 VVQGIWRLGAAMTMLQQPTSQADLAGWHAGTLRAPALLDTR-----------------------WVVIGEPFLAAAETLR 126
169628782  88 LVQGIWFSGASVTMLHQPTHRSDMRLWVEDTGRALAAVGSS-----------------------TVVVGDPFMAAASQFG 144
183980208  74 LVQGAWMCGAAVTMLHQPTHRSDLQAWAADTKKTLSMVGAS-----------------------TVVVGSPFQSAAQEFA 130
183983262  71 LAQALWLRGAALTMLQQPTPRSDLAVWIADTVRACRMLGAA-----------------------LVVVGDPFEMAADALA 127
183984938  70 VVQGIWRLGAAMTMLQQPTSQADLAGWHAGTLRALALLDTR-----------------------WVVIGEPFLAAAETLR 126
256374801  73 AVQGAWLAGASTTMLHQPTARTDLAEWAEDTVRVLGMIDSG-----------------------LVLLGAPFDALSPVLV 129
258654664  69 IAQAAWLAGASVTMLHQPTARTNLMTYAQDTAAVLSLVGAK-----------------------AAVLGDPFTEFAELLD 125
300790052 152 QKGIGFQLITELAA--AEPLpDVVVTDEGDTALLQLTSGSTADPKAVRITYGNLYSNVKAMVERAEFDFDVDVMVSWLPT 229
111225874 146 GGAGRVIPLAEAVGdpPAAPwRPPLLTADAPAILQLTSGTTGAPKIARISHGNLAANVEGIRVATSHEAVHGRMLSWLPL 225
118619948 135 KVGLRGLELSELLT--ADEG-RIVVAEEDSPAFLQLTSGSTGHPKAVSITYRNIEANGRALMAAASADVASDVVVSWLPL 211
118619238 127 AAGYRVIEIGESWP--ELAA-TEEPTGEDDVALYQLTSGSTGDPKAVAITHGNLFADVAAMTAEVHLDPEVDITASWVPL 203
169628782 145 AVAAQVLEMSALLD--GPPG-EIVQSDQDAIAFLQLTSGSTGTPKAVSISYRNIEANLRAMVSASGADPETDVVVSWLPL 221
183980208 131 KVGLRGLELSELLT--ADEG-RIVVAEEDSPAFLQLTSGSTGHPKAVSITYRNIEANGRALMAAASADVASDVVVSWLPL 207
183983262 128 AEGLIVCAVGSLRG--TGPA-AVVDTNDNDIAMRQLTSGSTGIPKAVEISHGNLVANIDASCQAVGITVDT-VMASWLPL 203
183984938 127 AAGYRIIEIGESWP--ELAA-TEEPTGEDDVALYQLTSGSTGDPKAVAITHGNLFADVAAMTAEVHLDPEVDITASWLPL 203
256374801 130 ERGITHHRITDL-D--ADPLtTPVEVPESATALLQLTSGSTAHPKAVRITHGNLWSNMEGMREAVHLDPEVDRMVSWLPL 206
258654664 126 GSGVLALTVDDLLAepGGPA-PDVEIGEDLPALLQLTSGSTSTPKAVRITHRNLWANIEAMCQAAQIRPG-EVMVSWLPL 203
300790052 230 FHDMGMVGFLTVPMTFG-VELVKITPVEFLSGPLIWPELITKYHGTTTAAPNFAYAIVGRRMARVDEDD-AYDLSKLRIA 307
111225874 226 SHDMGLIGGFILPMACGrCDALLSSPADYLARPASWMQLVSHHRATNTVGPGSAYAVAARLLRAGP----RLDLSCLAYA 301
118619948 212 FHDMGMMGLLIIPMYEG-MDAVHITPADFLNDPLLWAELITKHRGSITAAPNFAYSLLARRLRRAQDHA--FDLSSLRFA 288
118619238 204 SHDMALIAYLISPMFAG-NGAVYITPTEFVVSPLKWMQILTERRATITAAPNFAYSIISRRL-SAIEDG-TYDLGALRCV 280
169628782 222 FHDMGMMGFLIVPMCRA-MSTVSVTPMDFLGDPLLWAKLISTYRGSMTAGPNFAYSLLARRL-RKAPDG-AYDLSSLQFA 298
183980208 208 FHDMGMMGLLIIPMYEG-MDAVHITPADFLNDPLLWAELITKHRGSITAAPNFAYSLLARRLRRAQDHA--FDLSSLRFA 284
183983262 204 CHDMGMVGFICIPMKTG-NTVVVIRTDEFLRRPIVWAEMLSKFRANVTAGPNFAYSVLARVLERADPE--SINLSALRVA 280
183984938 204 SHDMGLIAYLISPMFAG-NGAVYITPTEFVVSPLKWMQILTERRATITAAPNFAYSIISRRL-SAVEDG-TYDLSALRCV 280
256374801 207 FHDMGMVGFLTLPMLYG-VDLVKVTPVDFLGRPVLWPELISRHRGTITAAPNFAYAVVAKRMRGLADG--ELDLSSLRIA 283
258654664 204 FHDMGMVGFLTLPMCRG-IELVTVTPTDFLASPLIWPTLISKYRGTITAAPNFAFALTARVLARPTTRElGLDLSCMRFA 282
300790052 308 LNGAEPIDETAVQTFVDAGARFKMPAECVFPAYGMAEATLAVSFAPLFTGLTLDVVEADALEA-ENRAVP--VPEGDprr 384
111225874 302 LCGGEPIDPAVVDDFLDAAGGHGFHPASFMPAYGLAEATVAVTFSAVGRGPRYDTVDADALAAgTTRFVP--PDPAVr-- 377
118619948 289 LNGAEGIDVATLERLATEGARFGLRRDAIVPAYGMAEATLAISVVRPGEGFRVCPPHPDLVAA-QGEAAA---------- 357
118619238 281 VTGAEPIDPATMAEFARQAGRFGLRHTALGAAYGLAEATVAVSFSPVDNPLTTESVCVEELEN-RGLALPacSCGGP--- 356
169628782 299 LSGAEAIDVATLERFVAEGARFGMRADAVVPAYGMAEATLAVSFVRRGEGYRVCPPHPDLVAA---QGTQ---------- 365
183980208 285 LNGAEGIDVATLERLATEGARFGLRRDAIVPAYGMAEATLAISVVRPGEGFRVCPPHPDLVAA-QGEAAA---------- 353
183983262 281 VNGAEPIDHRDLENLATVGARFGMGSGVPTPFYGLAEAALTVSAGAFGAPAVVDYVSRQRLSE-DHFAEP--VAADAq-- 355
183984938 281 VTGAEPIDPATMAEFARQAGRFGLRHTALGAAYGLAEATVAVSFSPVDNPLTTESVCVEELEN-RGLALPacSCGGP--- 356
256374801 284 LNGAEPIDPEAVRSFTAEGARFGLPPESVLCAYGMAETTLGVTFAPVFTGMAVDVVDADLLEA-ERRAEP--SAEPG--- 357
258654664 283 LNGAEPIDVAAVRAFLAAGAPFGLPETAVVCAYGMAEASLAVSFHPWGTPLKVDTVDAQALEI-ARRAVP--AESGR--- 356
300790052 385 gtdgVRSFALLGRPLDGLEAEIVD-DAGKRVDEREVGEIRLRGEAVTPGYLTMDGPLATQDEDGWLNTGDLGYLVD-GQI 462
111225874 378 ----TRRLALLGEPIPGLSVRVVDpDSGRVLPERKVGEVQVRGTSVAAYHDDPDSAAALRARDGWLATGDLGYLTG-GEL 452
118619948 358 ------PRVMLGPPVPGCDVRVVS-EDRTVLAPSEIGELEIRGDNVTAGYRTEAGFEPAVDAGGWLATGDVGYLAEnGQP 430
118619238 357 ----TKQFVTLGPPMSGVEVRIVA-ADGSNLPPRRMGEIAIAGDAVARHYLTTDGEVAAVDPDGWLFTGDLGYLTEgGEI 431
169628782 366 ----ASARVPLGLPLPGCEVRVVT-EDRQVLAPESIGELEIRGDNVTAGYRTASGFESMLDAQGWLSTGDIGYLTAdGQP 440
183980208 354 ------PRVMLGPPVPGCDVRVVS-EDRTVLAPSEIGELEIRGDNVTAGYRTEAGFEPAVDAGGWLATGDVGYLTEnGQP 426
183983262 356 ---gAQPVVCVGLPIPDMQIRIT--RDGQLQDARKVGVIELCSPSIGKRYVTVDGTIPLVDDAGWFDTGDLGYLDElGRL 430
183984938 357 ----TKQFVTLGPPMSGVEVRIVA-ADGSNLPPRRMGEIAIAGDAVARHYLTMDGEVAAVDPDGWLFTGDLGYLTEgGEI 431
256374801 358 ----ARSFALLGPPLPGLEIRVVD-DAGTLLGDRRVGRLQVRGEAVTPGYLTVDGPVPTTGPGGWLDTGDQGYLVG-EQV 431
258654664 357 ------SFPVLGPPLDGIEVAVRG-RDGAVLGDREVGVLHLRGECITEQYLTVDGPVATQDADKWLDTGDLGYLVD-GEV 428
300790052 463 VICGRRKDVIIMGGRNLYPTDIERAATSVEGVRAGNAVAVRLDAG--SRRERFAVVLESKLAGDAEAEKNLMKQVSARVR 540
111225874 453 VVCGRRKDVIILGGRNIYPEEVERAAARAEGARAGNTVAFGYPRPgqLGGEGLAVAVETRGADPAA----LRSAVTEEVR 528
118619948 431 VICGRKKDILIISGRNVHPEDIERSVVGIAGIRSGGVAAVRLATA--SASEGFVMVAESALHADDAESNRIRTEVADRVF 508
118619238 432 VVCGRRKNVIIVAGRNIFPADIERLAASVHGIRRGGVVAFGVTLA--DRREEIRIVAETVADPSIEDGRELRRQIAQNVR 509
169628782 441 VICGRKKDILIISGRNVHPEDIERSVAGISGVRSGGVAAVRLHTA--SAGEGFAMVAESALHADIAESERIRAEVADRVY 518
183980208 427 VICGRKKDILIISGRNVHPEDIERSVVGIAGIRSGGVAAVRLATA--SASEGFVMVAESALHADDAESNRIRTEVADRVF 504
183983262 431 YVCGRAKDMIVLAGRNLYPHDIERAAASVEGVRKGCVAALRLDTD----REGFAVLAEVYDRFDESELTQLRRAIAARVS 506
183984938 432 VVCGRRKNVIIVAGRNIFPADIERLAASVHGIRRGGVVAFGVTLA--DRREEIRIVAETVADPSIEDGRELRRQIAQNVR 509
256374801 432 VVCGRLKDVIIMGGRNIYPTDVERAATAVDGVRAGNAVAVRLDAG--TRRERFAVVVESRFASEEEEVKRLTKAITAKVV 509
258654664 429 VVCGRVKDVIIMGGRNIYPTDIERVAQSIDGVRAGNAVAVRWTTP--SGRESFAVAVESREAGDQDAAERIRQAVRSAVT 506
300790052 541 DAVDMRPYAVVVLPAGSLPKTPSGKVKRAATAQQFA 576
111225874 529 AALGVSPHVVLVLEPGSVPKTPSGKLQRAEARRRFA 564
118619948 509 VNLGVSPRAVHVVPAGWLPKTSSGKLRRRQTSERLR 544
118619238 510 GATGLRP-TVLLVGKGNVPKTASGKIRHVMARELFG 544
169628782 519 RTLGVSPRDVHVVPAGWIPKTSSGKLRRRATSERLK 554
183980208 505 VNLGVSPRAVHVVPAGWLPKTSSGKLRRRQTSERLR 540
183983262 507 SHVGHAPREVRLLAPGSLPKTTSGKLRREGARALM- 541
183984938 510 GATGLSP-TVLLVGKGKVPKTASGKIRHVMARELFG 544
256374801 510 DAVGVRPFSVVVLPPGSVPKTPSGKLRRTSAAALVT 545
258654664 507 AEIGARPATVSVLPVGSLPKTPSGKLQRSAAARLIT 542
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