Conserved Protein Domain Family
BREX_3_BrxF

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NF033453: BREX_3_BrxF 
BREX-3 system P-loop-containing protein BrxF
This family of proteins that are about 150 amino acids in length includes BrxF from type 3 BREX (bacteriophage exclusion) systems. Most members have the P-loop motif GxxGxGKT, but the region is surprisingly poorly conserved in a sizable fraction of otherwise strongly similar proteins.
Statistics
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PSSM-Id: 468038
Aligned: 48 rows
Threshold Bit Score: 146.1
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
microTFA:SGRAN_2871   3 ERLQQLVADATQLN-SKLVLVVANSGGgKTALLAEFAKThDLQIINVGSELSNLLLPIPSSQRSFEVLGVLRDMLshHRD 81 
WP_068882977          1 MDLETLLEQNRNNY-YKMLVIVDNSKQ-QEKITWTLAAK-GWQAYNVTDHILELIEQIPEKERKLRIGRIIKEWV--KDL 75  Dehaloba...
WP_082816648          4 QRIVKFVHDTKTLD-EKLVLIVGQPGSgKSNIMRELSAMrGWEYIDSRILVTEELLELMPKVRPVEAPQIMDSVLt-KLE 81  Anaerosp...
WP_068347594          7 YELKYFIRELTNSNpTILYLIVGKHGAgKSKALKKISEQlNEFVVNLNMELSKALLEVPIMDRPYRAMKFFDKFP--EME 84  Kosmotog...
WP_043745917          3 EQLDRIVDEVEALQ-SKLVLLIAEGGMsKSSLLHELAQRrASTVMNIGSELGARLAAPPFKQRALAVPEALRELAdrHAA 81  Zoogloea...
WP_062194137          3 TRLDRLVDEIAALH-SKLILLVGRPGCgKSALLAELANQrGMKVMNVGAVLGKRLAALPQRQRALQANVALRELAdeYAS 81  Pseudomo...
WP_051534279          5 DEILGCINKLDSHY-YKLILLVGKTGSgKTRMLKALAAAtDGAVADLNVELSKMLKNLPKMERCHYVQDFLDVVLr-QSS 82  Desulfit...
WP_004621787          5 NEVKKMSNSMLDKY-YKLILLIGKNGSgKTSLINELCAAnTYSYINLNLALSEKLKDVPIGDRCYCVQDFIDEIIr-NAS 82  Ruminicl...
WP_044663769          5 NEFKKSVLTLPDMY-YKLLLLVGSSGAgKTAIIKKICIDnKYRYVNFNHALSKKLKDIPIGDRCYSIHDCIDEIAe-DNV 82  Syntroph...
WP_014759121          5 ENIRDALAILQNEY-HKLILVLTLL-DdKAEVVEKISNKyAYDVLNVNLRLSEKLISVPISERWLHVDEFFSRLLn-DYK 81  Thermoan...
microTFA:SGRAN_2871  82 RGVVVLDNIEVMFDAEL-KINPFDTIKRLAHAMTVVVAWPGNFKDGRLLYAKVGHPEH-CDVAVDGAIVLEL 151
WP_068882977         76 PDKVVLYDTSILYSPELgRLNPVGAFKYKSREKEIIVILNGQIYGERIRYSEYGREDF-CEMDISELIHAKI 146 Dehalobacter sp....
WP_082816648         82 AEVILLDGIQALFAPVL-QLDPLSMLRRLSRKHTIVSAWPGQFENGKLVFNQDGRLPY-REYDAEGLSLVQV 151 Anaerosporomusa ...
WP_068347594         85 NNFLLLDNIELLFEPEL-KLHALSALRNIARKKSVIATWPGEVIRNKLLHAKRGHSEYfEGYLEDEIILMCS 155 Kosmotoga arenic...
WP_043745917         82 HGVVLLDNIELLFDRSL-RLDPLDLLKQLARARRVVAVWPGQLREGRLIYAEMGHPEH-QDYSIDGLVPFEI 151 Zoogloeaceae
WP_062194137         82 GDLLLLDNIELLFDQSL-KLDPLDLLKRHAHARRVVAVWPGELRDGRLIYAEMGHPEY-QDYGLDGLVPFEI 151 Pseudomonadota
WP_051534279         83 GQPLFLDNTEILFSSHL-KVDPIGMLKNASRYQPLVVTINGVIDNNKLTYAEPNHPDF-IVYKVSELGCRYY 152 Desulfitibacter ...
WP_004621787         83 GDFIVLDNIELIFSKHL-QLEPLGVLKNIAKYRKTIVAWQGSITNGYLTYAEPTHEDY-VKYKMDELECLYI 152 Ruminiclostridiu...
WP_044663769         83 SDFLVFDNIEIIFSKHL-QIEPLRTLKNIAKYRNIIAAWSGSIKDGYLTYAEPWHDDY-VRYSLSDLECIYI 152 Syntrophaceticus...
WP_014759121         82 TDVIVLNSIEMLFETHL-KVDPLRLLKSVSRYRKIIAIWTGDYTDGVLTYAEPSHPEY-RRYKNDDLDFIMV 151 Thermoanaerobact...
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