Conserved Protein Domain Family
YcaO_for_S12

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NF040716: YcaO_for_S12 
30S ribosomal protein S12 methylthiotransferase accessory factor YcaO
YcaO acts as a partner for RimO to achieve the modification of ribosomal protein S12. Homologs of YcaO are involved a wide variety of RiPP (ribosomally translated, post-translationally modified peptide) natural product biosynthesis pathways. Some members of this family have an additional N-terminal OsmC-like domain.
Statistics
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PSSM-Id: 468680
Aligned: 34 rows
Threshold Bit Score: 850.338
Created: 24-Apr-2023
Updated: 4-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_005298132   3 TFIPGKDAALEESIERFQTQLKNLGFNIEEASWLNPVPNVWSVHIRDVDAPMNFTNGKGATKKAALASALGEYFERLSTN 82  Photobacterium ...
WP_008284141 150 TYIEGKDLPLEDTIAHMTGILESLGMKIEVASWRNIVPHVWSLHIRDAASPMCFTNGKGSTKESALCSALGEFIERLSCN 229 gamma proteobac...
WP_010380427 150 TFILGKDLPLEQTIANMTGILSDLGMKIEVASWRNIVPNVWSLHIRDAASPMCFTNGKGATKESALCSALGEFIERLNCN 229 Pseudoalteromon...
WP_019952487 150 TWIEGKDLPLEQTVANMTAILERLGMKIEVTSWRNIVPNVWSLNIRDAASPMCFTNGKGASREAALCSALGEFIERLSCN 229 Kushneria aurantia
WP_020592424 147 TVVLGKDLPLEQTIANMTSILSDIGIKIEIASWRNIVPNVWSLHIRDAASPMCFTNGKGATRESALCSALGEYIERMSCN 226 Kiloniella lami...
WP_014243831 152 TMILGKDCSLEETIENMTALLKDLGINIEIVSWRNPVPHVWSVHIRDADSPICYTNGKGSTKDSALCSALGEYLERISNN 231 Halobacteriovor...
WP_008484855   4 TFIPGKDAALEDSIARIGGAIEALGFTIEEARWLNPAPYIWSVHIRDKDCPQVFSNGKGATREASLASAYGELIERLSTR 83  Gallaecimonas x...
WP_017430411   4 TFIPGKDAALETSLDTLKGHIEGLGFNIVEARWLNPAPHIWSVHIRDRDCPQVFANGKGANRKAALASAYGEMLERLATR 83  Halomonas jeotgali
WP_011370688   5 TFIKGKDACLEDSINKMQTLLTTAGFEIEEASWLNPVPNVYSVHIRDKNCPALFTNGKGASRKATLASALGEFFERLETN 84  Hydrogenovibrio...
WP_019896379   5 TQIIGKDACLEDSIARMQSSLTELGFDIDQAKAANPVDNVYWLHIRDRFCPALFTNGKGASRKATLASALGEYLERLQTN 84  Hydrogenovibrio...
WP_005298132  83 YFYADYYLGQDIANS----EF----VHYPNEKWFPIDFEENLpPEGILDERLTQFYDPTME-LLGTDLVDLQSGNMERGV 153 Photobacterium ...
WP_008284141 230 FFYNDQYFGEEIAHS----EF----VHYPSERWFQPGPDDAL-PEGLLDEHCLSLYNPDGE-LQASHLIDTNSGRADRGI 299 gamma proteobac...
WP_010380427 230 FFYNDQFFGEEIANA----EF----VHYPNEQWFKPGDNDEL-PAEILDGYTREIYDPEGE-LRGSNLIDTNSGNIERGI 299 Pseudoalteromon...
WP_019952487 230 FFYNDQFFGREIANS----DF----VHYPDERWFKPGADDAV-PEGLLDDHCRAIFDPDGE-LRGSHLIDTNSGRRDRGI 299 Kushneria aurantia
WP_020592424 227 FFYNDHYFGEEIANR----EF----VHYPNEKWFKAGADDAL-PEGLMDERCLELYNPDGE-LRASHLIDTNSGQIERGI 296 Kiloniella lami...
WP_014243831 232 YFYNDYYLGADNAQA----EF----AHYPDEKWFKLQANGQM-PEGLMDDYLKDIYSVDGE-LRAHHLVDTNTGNKERGV 301 Halobacteriovor...
WP_008484855  84 YLWADFRLTSALNEF----GH----VHQSDERWYDV--DGQW-PEELLDEHCRAIYDPEGD-LELSDLIDHNGGDSGKGV 151 Gallaecimonas x...
WP_017430411  84 YLWADFYLTPAQKDF----PF----IHQAEEKWWSP--DTPL--DQVLDP---VFYQRYGEdLTLAELRDMNGGDADHSV 148 Halomonas jeotgali
WP_011370688  85 YFFSDFYLEEALVNReddvSWnergLYFPDEKVFELSD-----FRQCLSPELWEIYDPEGE-MVAEDLLSLN--DAEPKI 156 Hydrogenovibrio...
WP_019896379  85 YFFSDYFLCAHKTAPta-sDW----LYFPDEKRFPLEA-----FRDTLTPELWALYDPEDE-LVGEDLLSLN--DQADAI 151 Hydrogenovibrio...
WP_005298132 154 CCLPFERQSDNETVYIPMNIIGNLYVSNGMSAGNTKMETRVQGMSEIFERAVKNRIIAERISLPEIPAEVIAQYPSIKES 233 Photobacterium ...
WP_008284141 300 VALPFVRQSDQTTVYIPSNLIENLFLSNGMSAGNTLAEAQVQCLSEIFERAVKREILEQEIALPDVPAEVLAKYPQIVEG 379 gamma proteobac...
WP_010380427 300 CSIPYTRHSDGETVYFPSNLIENLFLSNGMSAGNNLFEAKVQCLSEIFERAVKKQIIEQEIVLPDVPEDVLAKFPGIVAG 379 Pseudoalteromon...
WP_019952487 300 VALPFVRHSDGETVWFPSNLIENLYLSNGMSAGNSVAEAQVQCLSEIFERAVKKQIIEQELALPEVPAAVLDRYPALVEG 379 Kushneria aurantia
WP_020592424 297 CALPFTRSSDQKTVYFPSNLIENLFVSNGMSAGNTLYEAKVQCLSEIFERAIKRQIIEQEIVLPDVPKEILAKYPRVLAG 376 Kiloniella lami...
WP_014243831 302 CAIPFTRNSDKETVYIPVNLIGNLFVSNGMSAGNTIYEARVQCLSEIFERAVKNDIISNEMALPDVPMEIIEKYPTILEG 381 Halobacteriovor...
WP_008484855 152 CALPYVRQSDGQTVYVPVNLIGNIFVSNGMSAGNTQAEAQVQGLSEIFERAIKNRIIVEDIALPLVPQSVLDRYPHIDAG 231 Gallaecimonas x...
WP_017430411 149 CTLPYVRQRDGATVDVPVNLIGNMYVSNGMSAGNTRDEGQVQGLAEIFERAIKERIIRDAITLPEVPAAVLARYPRIQAG 228 Halomonas jeotgali
WP_011370688 157 RCLPLTNASSHDTVYFPMNLFSNLYASNGLSAGNTPEEALVQGLSEVFERWVKRKILTENLCLPEVPEAIVQRYPTVVKA 236 Hydrogenovibrio...
WP_019896379 152 RCLPLQAVSRQKTVYFPANLLSNFYASNGLSAGNSFEEAETQGLSEVLERWVKARILRENLCLPEVPETVLEEYPVVARA 231 Hydrogenovibrio...
WP_005298132 234 IDCLEAEGFPIFCFDASLGGQYPVICVVLMNQDNNTCFASFGAHPSFEVSFERTVTELLQGRGLKDLDVFPEPSFDDEEV 313 Photobacterium ...
WP_008284141 380 IEALEAQGFPILVKDASLGGQFPVMCVTLMNPRNGGVFASFGAHPNFEVALERSLTELLQGRSFEGLNDVPAPTFNSHEV 459 gamma proteobac...
WP_010380427 380 IKGLEEQGFPVVVKDASLGGQFPVMCVTLMNPKTGGVFASFGAHPSLEVALERSLTELLQGRSFEGLNDVPKPTFNSMAV 459 Pseudoalteromon...
WP_019952487 380 IKALEAQGYPLLVRDASLGGRFPVACITLMNPRTGGVFASFGAHPNMGVALERSLTELLQGRSFEGLNDLPQPTFSSEAV 459 Kushneria aurantia
WP_020592424 377 IEELENKGFPIVVKDASLGGKFPVMSVTLMNPKTGGVFASFGAHPSFEVALERSLTELLQGRSFEGLNDVPPPTFNSPAV 456 Kiloniella lami...
WP_014243831 382 IKKLEEQGFPILVKDASLGGKFPVMCVTLMNPRTGGVFASFGAHPKFEVALERSLTELLQGRSFEGMNDIALPTFNEFAV 461 Halobacteriovor...
WP_008484855 232 IKALQAEGFGIRALDASLGGRYPVMCVVLQHPKDGGIYASFGAHPKFGVALERALTELLQGRALDELEGFPAPTTDMEQV 311 Gallaecimonas x...
WP_017430411 229 MAALEANGFQLRALDASLGGQYPVMSIVLLHPDDGGLYACFGAHPRFEVALERALTELVQGRALDELGGFPPPTADLDLV 308 Halomonas jeotgali
WP_011370688 237 RKALQEQGIDVSIRDSSLGGHFPVMNVTLFEQKTGRCFASFGAHPIFEVALERTLTESLQGRSLDMLDGFQLPVFDEGLV 316 Hydrogenovibrio...
WP_019896379 232 LAAMREQGVAVSVRDASLGGRFPVINVTLFDQKNGRCFASFGAHPLFEVALERSMTEALQGRSLNDLDGFDLPIFDETLV 311 Hydrogenovibrio...
WP_005298132 314 GDHHNLETHFIDSSGLISWDLFKQEADFEFVHWDFS---------GTTEQEFTRLLGMFHQE-GTDVYISDYNHLGVDCC 383 Photobacterium ...
WP_008284141 460 SEPNNFVEHFIDSTGVVSWRFFSASADVAFCEWDFS---------GTTEEEARTLFGILDDL-GKEAYMMVHDDLGAPVC 529 gamma proteobac...
WP_010380427 460 SEPENFVEHFIDSTGVISWRFFSAKHDYEFVEWDFT---------GTNEEECDKLFAILKDL-GKEAYIAEFTDMGT-AC 528 Pseudoalteromon...
WP_019952487 460 TEPNNFVEHFIDSSGLVSWRFFSDRADVEFYDWDFS---------ATTEEEQQRLFAILQAM-NLEAYVAVHEELGAPAC 529 Kushneria aurantia
WP_020592424 457 TEPGNFVEHFIDSTGVISWKFFSAKQDFEFCEWDFS---------GTTEEENECLMEILAGL-GKEVYIATYDDFGGTAC 526 Kiloniella lami...
WP_014243831 462 KEHNNLVDHFIDSTGVVSWKFFSSKSDFEFVHWDLK---------GSTEEEYHYLMSILKDL-DKEVYIADYQELGACAC 531 Halobacteriovor...
WP_008484855 312 TDPHNLELHFIDSSGYVGWGFLSDKPDFEFADWDDQ---------HDNAFERQALIELLHDE-GHQVYIAEHTALGAYAC 381 Gallaecimonas x...
WP_017430411 309 TDPHNLELHFIDASGYVSWALIGETPDVDFCDWDDT---------RGNAEQRDSLIELLHQE-GHDVYIAEHRELGAYAS 378 Halomonas jeotgali
WP_011370688 317 ADDENIENHFIDSSGLIHAKFISHQYDFEFNEWDFD---------GDTQAQYDLLIKKVHEQ-GAEVYFAHYDHFGINAC 386 Hydrogenovibrio...
WP_019896379 312 ASDENIENHFIDSSGWLHARFISHQPDFDFVYWQVTqamprledvSTSAAQRAGLIDLIEKElSAEVFIARYQFAGLPAC 391 Hydrogenovibrio...
WP_005298132 384 RIIVPGWSEIYPVEELIEANNNVAMELRETFLALPsvEWDSEQYAEMYSILEEEGFDDFNRLYEIIGLVPDAGSAWQTLR 463 Photobacterium ...
WP_008284141 530 RILVPDYSEVYPAEDLVWDNTNMALDYREDILNLH--RLSDEALADLYDRLEDSQIDNYTTIITLIGIEFDENTVWGQLT 607 gamma proteobac...
WP_010380427 529 RILVPGYSEVYPAEDLIWDNTNKALQYREDILNIH--SLEDEALADLVNRLEESQLDNYIDIITLIGVEFDENTVWGQLT 606 Pseudoalteromon...
WP_019952487 530 RILVPGYSEVYPIEDLVWDNTNMALDFRADILDLH--RLDDAQLSALLERLEESELDEQMKVLNLIGIEFDDNSVWAELT 607 Kushneria aurantia
WP_020592424 527 RILVPDYSEVYPVEDLIWDNTNKALMFREDILNIH--SLSDAQLEGLLERFEEFELDPYTVIANLIGIEFDENTVWGKLD 604 Kiloniella lami...
WP_014243831 532 RILVPDYSEIYQAEDLVWDNHNKGNDFRERILSVH--SLSEEKLQELLEDLEEYELDDHQPVSELIGVAFDEVSNWGQLV 609 Halobacteriovor...
WP_008484855 382 RILVPGFSDIYPADELVWHNNNQALDFRPVLFDLN--GATEEDHRELLEALDQYSVNDQLRVLEWAGIVGDKGTPWARLR 459 Gallaecimonas x...
WP_017430411 379 RILVPGFSDIYLPDELKWHNNNQAVPHRATLFALP--DAGADAWQALLDGLEDDNVNDQMSVLEWAGIVPDPETAWERLR 456 Halomonas jeotgali
WP_011370688 387 RIVVPEMSEVFPMHELVDNNQNRGRVLREILLELSl-SDKADRFENALEQIEMMGFSEHQGVANLIGLLPDPNSYWKKFK 465 Hydrogenovibrio...
WP_019896379 392 RIVVPGVSEVFPLTELLDNNQNRGRQLREALFDLA----DTQDYAQCYHELESLAFADHQGVANLVGLLPDPDTIWKKMT 467 Hydrogenovibrio...
WP_005298132 464 IGELKCLLALAGGDLELALEHASWCVDYNVStySKERARFFRCLVASLKLaldeeRDPAQYKHAF-ERQFGTETVAAAWG 542 Photobacterium ...
WP_008284141 608 ILELKIMLCLALQQHEDALDWVEMFLQFNDN--TVERNLFYRAVNAVLEItlddeLVLDDFRFNL-GRMYGEETMESVVG 684 gamma proteobac...
WP_010380427 607 ILELKILIYLALGDIEAAIELVETFLQYNDN--TVERGLFYQAMHATLEValdeeLEIEDYIHSF-TRMFGKEVMDAVIG 683 Pseudoalteromon...
WP_019952487 608 LLELKLLIQLALGQLEDALDRVEMFLQFHDN--SVARELFYRAVHALLEIeldnsLVRDDFLRNL-RRMYGEEMTAAAVG 684 Kushneria aurantia
WP_020592424 605 VGELKILIYLALKQYEEAKEAVGDFLNFNEN--TVARVLFYRAMDAVLDItlddeLDIDDYVPNL-TRMFGPAVMNDVVG 681 Kiloniella lami...
WP_014243831 610 VGELKAMINLALQNLEEAKFNVDILNQFNEY--APDRKKYYQILNIVLDIaideeLDMEDYTENL-TKMYGEVLVREALE 686 Halobacteriovor...
WP_008484855 460 IGELRLWLLLALSEQEEAYEQLGSVLASGHL--TDDERLLYRAIFAVLELtv-egKDLSDFEPSL-VNYFGADKLALAKG 535 Gallaecimonas x...
WP_017430411 457 VGELKLWLLLALGEQEAAFEQLALVRASGNL--VEDDIRCFDALASVLELtl-agESPDDYARAL-QFYHG-DALARATA 531 Halomonas jeotgali
WP_011370688 466 IVELQMWLLLAVKDYEMAYERLQECHYFVD---DEAMALFYKALGFALDVlle--dsLTEYPLSVqAQLFGEKIIEKVWR 540 Hydrogenovibrio...
WP_019896379 468 ISDLRVFLLLKLQAVEEALEAVEIASIYQQ---DPDWQRFYQALAFALEAql-epRAGVNQKALQ-ATLFGQQRVDEVWA 542 Hydrogenovibrio...
WP_005298132 543 SIEGTVRFYGLTAGDLSMSQFSAHQKLLASYQKLQA 578 Photobacterium damselae
WP_008284141 685 LVAGTQRFHGLTPTNTQLEGLEKHQRLIESYKKLHA 720 gamma proteobacterium HTCC5015
WP_010380427 684 SINGDVKFYGLTPTNMQLEGLDKHLRLIDSYKKLHA 719 Pseudoalteromonas rubra
WP_019952487 685 SVDGNVRFHGLTPTSMALEGIERHQRLIESYQKLHQ 720 Kushneria aurantia
WP_020592424 682 AVTGDVQFPGLTKTSMKLEGLDKHLRLIESYKKLHK 717 Kiloniella laminariae
WP_014243831 687 TVSAEVKFFGLEETSIELTNIDKHQRLVESYNKLQV 722 Halobacteriovorax marinus
WP_008484855 536 LVAGTERFPELGKLDPD-TPTQGHRRLMEAYAKVLK 570 Gallaecimonas xiamenensis
WP_017430411 532 LASGMAVFPGLDAMHPDAPTL-AHRRLLEGYAKVLK 566 Halomonas jeotgali
WP_011370688 541 NINGEEVFGGLDIGMKAFENSQNHQALMTVYQKVQR 576 Hydrogenovibrio crunogenus
WP_019896379 543 HLDGTQFLFDAPIGEAMFAQSQAHQALCAVHERLRP 578 Hydrogenovibrio halophilus
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