4GRC,4GT2


Conserved Protein Domain Family
tat_substr_1

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TIGR01412: tat_substr_1 
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Tat-translocated enzyme
This model represents a small family of proteins with a typical Tat (twin-arginine translocation) signal sequence, suggesting that the family is exported in a folded state, perhaps with a bound redox cofactor. Members of this family show homology to Dyp, a dye-decolorizing peroxidase from Geotrichum candidum that lacks any typical heme-binding site.
Statistics
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PSSM-Id: 273606
Aligned: 8 rows
Threshold Bit Score: 584.056
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4GRC_A        26 SPAPAPSPSRRSLIGWG-GAGLALGAAAAaG--GaVAMDRAGADADPAga----dAGSAVPFHGAHQAGIATPVQDRLHF 98  Streptomyces co...
CAA22235      29 AATAPQGVSRRRLLGTAgATGLVLGAAGA-AagYaAAPSSAATPLTSL-------GSERAMFHGKHQPGITTPMQARGHL 100 Streptomyces co...
CAB61722       6 SPAPAPSPSRRSLIGWGgAGLALGAAAAA-GgaVaMDRAGADADPAGAd------AGSAVPFHGAHQAGIATPVQDRLHF 78  Streptomyces co...
WP_001199176   5 DKNGVNEPSRRRLLKGIgALALAGS----------CPVAHAQKTQSAPgtlspvaRNEKQPFYGEHQAGILTPQQAAMML 74  Escherichia coli
WP_003753644   2 STNNPTQPTRRTLFKTAiAAGAVGAIGGYlG--GkKQGETAERTAESQh------SPQAYPCYGEHQAGIVTPQQAFSIM 73  Neisseria polys...
WP_000186217   6 QVNDSTQFSRRTFLKMLgIG---GAGVAIgA--SgVGSMWSFKSMFNTpe---dpEKDAYEFYGKVQPGITTPTQKTCNF 77  Staphylococcus ...
P39597         4 EQKKPEQIHRRDILKWGaMAGAAVAIGASgLggLaPLVQTAAKPSKKDek----eEEQIVPFYGKHQAGITTAHQTYVYF 79  Bacillus subtil...
4GT2_B        49 AATAPQGVSRRRLLGTAgATGLVLGAAGAaA--GyAAAPSSAATP--Lts----lGSERAMFHGKHQPGITTPMQARGHL 120 Streptomyces co...
4GRC_A        99 AAFDVTT-EDRAAFVALLKEWTAAARRLTAGHAvgegaygglpeAPPDDTGEALGLKPSRLTLTIGFGPSLFT-R----- 171 Streptomyces co...
CAA22235     101 VAFDLAAgAGRKEAAALLRRWSDTARRLMAGEP-----------AGSRDTDVARDAGPSSLTVTFGFGHSFFG-R----- 163 Streptomyces co...
CAB61722      79 AAFDVTT-EDRAAFVALLKEWTAAARRLTAGHAvgegaygglpeAPPDDTGEALGLKPSRLTLTIGFGPSLFT-R----- 151 Streptomyces co...
WP_001199176  75 VAFDVLA-SDKADLERLFRLLTQRFAFLTQGGAapetp--nprlPPLDSGILGGYIAPDNLTITLSVGHSLFDeR----- 146 Escherichia coli
WP_003753644  74 CAFDVTA-QSAKQLENLFRTLTARIEFLTQGGEyqdg---ddklPPAGSGILGKAFNPDGLTVTVGVGSSLFDgR----- 144 Neisseria polys...
WP_000186217  78 VALDLKS-KDRDAIKAMFKKWTVMADRMMDGDTvgkps--nnplMPPVDTGESIGLGASKLTITFGISKSLMK-K----- 148 Staphylococcus ...
P39597        80 AALDVTA-KDKSDIITLFRNWTSLTQMLTSGKKmsaeq--rnqyLPPQDTGESADLSPSNLTVTFGFGPGFFE-Kdgkdr 155 Bacillus subtil...
4GT2_B       121 VAFDLAAgAGRKEAAALLRRWSDTARRLMAGEPa-----------gSRDTDVARDAGPSSLTVTFGFGHSFFG-R----- 183 Streptomyces co...
4GRC_A       172 FGLADLRPEALADLPKFPGDNLDRARSGGDLCVQACADDPQVAVHAIRNLARIGFGKVVVRWSQLGFGktSs---tTPDE 248 Streptomyces co...
CAA22235     164 TGLEEQRPVALDPLPDFSSDHLDKNRSNGDLWVQIGADDALVAFHALRAIQRDAGAAARVRWQMNGFN--Rsp-gaTAHP 240 Streptomyces co...
CAB61722     152 FGLADLRPEALADLPKFPGDNLDRARSGGDLCVQACADDPQVAVHAIRNLARIGFGKVVVRWSQLGFG--Kts-stTPDE 228 Streptomyces co...
WP_001199176 147 FGLAPQMPKKLQKMTRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFI--SdhaarSKGK 224 Escherichia coli
WP_003753644 145 FGLKDKKPVHLQEMRDFSNDKLQKNWCDGDLSLQICAFTPETCQAALRDIIKHTAQTAVIRWSIDGWQ--Pk---sEPGA 219 Neisseria polys...
WP_000186217 149 IGLSSKIPDAFKDLPHFPNDQLIDDYSDGDIMIQACSNDSQVSFHAVHNLVRPFRDIVKVRWAQSGFI--S-----AKGK 221 Staphylococcus ...
P39597       156 FGLKSKKPKHLAALPAMPNDNLDEKQGGGDICIQVCADDEQVAFHALRNLLNQAVGTCEVRFVNKGFL--Sg----GKNG 229 Bacillus subtil...
4GT2_B       184 TGLEEQRPVALDPLPDFSSDHLDKNRSNGDLWVQIGADDALVAFHALRAIQRDAGAAARVRWQMNGFNrsPg---aTAHP 260 Streptomyces co...
4GRC_A       249 QTPRNLLGFKDGTRNIAGTEKDrLDRFVWA--AEk-----DGTPWMTGGSYLVARRIRMHIETWDRASLQEQEDVFGRDK 321 Streptomyces co...
CAA22235     241 MTARNLMGQVDGTRNPKPGEAD-FDRRIFV--PEepeagkGGPAWMANGSYVVVRRIRMLLDDWEELSLKAQEDVIGRRK 317 Streptomyces co...
CAB61722     229 QTPRNLLGFKDGTRNIAGTEKDrLDRFVWA--AEk-----DGTPWMTGGSYLVARRIRMHIETWDRASLQEQEDVFGRDK 301 Streptomyces co...
WP_001199176 225 ETPINLLGFKDGTANPDSQNDKlMQKVVWVtaDQ------QEPAWTIGGSYQAVRLIQFRVEFWDRTPLKEQQTIFGRDK 298 Escherichia coli
WP_003753644 220 MAARNLLGFRDGTGNPKVSDPKtADEVLWT--GVaan-slDEPEWAKNGSYQAVRLIRHFVEFWDRTPLQEQTDIFGRRK 296 Neisseria polys...
WP_000186217 222 ETPRNLMAFKDGTINPR--KNNqLKDYVFI--DD------G---WAKHGTYCVVRRIQIHIETWDRTALEEQEATFGRKR 288 Staphylococcus ...
P39597       230 ETPRNLFGFKDGTGNQSTKDDTlMNSIVWI--QS------GEPDWMTGGTYMAFRKIKMFLEVWDRSSLKDQEDTFGRRK 301 Bacillus subtil...
4GT2_B       261 MTARNLMGQVDGTRNPKPGEAD-FDRRIFV--PEepeagkGGPAWMANGSYVVVRRIRMLLDDWEELSLKAQEDVIGRRK 337 Streptomyces co...
4GRC_A       322 GEGAPVGK---AKERDEPFL-------K-AMKPDAHVRLAHPDsn---gGATLLRRGYSFTDGTDG-LGRLDAGLFFLAY 386 Streptomyces co...
CAA22235     318 SDGAPLSGgsgATESTEMDLektdgsgElVVPINAHARITRPDqn---gGAAMVRRPFSYHDGFDA-DGVPDAGLLFVCW 393 Streptomyces co...
CAB61722     302 GEGAPVGK---AKERDEPFL-------K-AMKPDAHVRLAHPDsn---gGATLLRRGYSFTDGTDG-LGRLDAGLFFLAY 366 Streptomyces co...
WP_001199176 299 QTGAPLGM---QHEHDVPDYasd-pegK-GIALDSHIRLANPRtae-seSSLMLRRGYSYSLGVTN-SGQLDMGLLFVCY 371 Escherichia coli
WP_003753644 297 YSGAPMDG---KKEADQPDFakd-pegN-TTPKDSHIRLANPRdpeflkKHRLFRRAYSYSRGLAS-SGQLDVGLVFVCY 370 Neisseria polys...
WP_000186217 289 HSGAPLTG---GKEFDEIDLkakdshgEyIIDKDAHTRLAKEA------NTSILRRAFNYVDGTDDrTGNFETGLLFIAF 359 Staphylococcus ...
P39597       302 SSGAPFGQ---KKETDPVKL-------N-QIPSNSHVSLAKST------GKQILRRAFSYTEGLDPkTGYMDAGLLFISF 364 Bacillus subtil...
4GT2_B       338 SDGAPLSGgsgATESTEMDLektdgsgElVVPINAHARITRPDqn---gGAAMVRRPFSYHDGFDA-DGVPDAGLLFVCW 413 Streptomyces co...
4GRC_A       387 QRDIRTGFVPVQRNLa-TDALNEYIQHVGSAVFAVPPGVRDAdD-WWGSTLFG 437 Streptomyces coelicolor A3(2)
CAA22235     394 QADPLRGFVPVQRKLdrGDALSQFIRHEASGLFAVPGGAAEG-E-YVGQRLLE 444 Streptomyces coelicolor A3(2)
CAB61722     367 QRDIRTGFVPVQRNLa-TDALNEYIQHVGSAVFAVPPGVRDA-DdWWGSTLFG 417 Streptomyces coelicolor A3(2)
WP_001199176 372 QHDLEKGFLTVQKRLn-GEALEEYVKPIGGGYFFALPGVKDA-NdYLGSALLR 422 Escherichia coli
WP_003753644 371 QANLADGFIFVQNLLn-GEPLEEYISPFGGGYFFVLPGVEKG-G-FLGQGLLD 420 Neisseria polysaccharea
WP_000186217 360 QK-ATKQFIDIQNNLgsNDKLNEYITHRGSASFLVLPGVSKG-G-YLGETLFD 409 Staphylococcus aureus
P39597       365 QKNPDNQFIPMLKALsaKDALNEYTQTIGSALYACPGGCKKG-E-YIAQRLLE 415 Bacillus subtilis subsp. subtilis str. 168
4GT2_B       414 QADPLRGFVPVQRKLdrGDALSQFIRHEASGLFAVPGGAAEG-E-YVGQRLLE 464 Streptomyces coelicolor A3(2)
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