6VH5,2QMX,7AM0,4LUB


Conserved Protein Domain Family
PheA2

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COG0077: PheA2 
Prephenate dehydratase [Amino acid transport and metabolism]
Prephenate dehydratase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Statistics
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PSSM-Id: 439847
Aligned: 943 rows
Threshold Bit Score: 141.005
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6VH5_A        24 TNRISFQGEAGANSDTACRNMF----P-D---M---EPLPCPTFEDAFNAVETGAADLAMIPIENTLAGRVADIHYLLPL 92 
WP_015120568  33 ADELGYLGPTGTYSEQATKVYQs---Q-TpgfE---KVVPYKTITAVTTAIKSSEVKRGLIPIENSDSGFVAETYRLIFE 105
WP_038470792   1 -M-IGYLGPEGSYTFSAALSFN----TiE-------DLIPHNNIGRLFYALENHEVEGIIVPFENMKQGISFDVLGRVRK 67 
WP_100257451   4 SARLACLGPIGTYSSKAATQYLq---R-N---TqiqDVLYFDNVEDFLHQPLQ-TYDHIIVAIENTCEGFISPNIQGVIA 75 
WP_011233302   1 -MRIATLGPAGTFSEVAAGLYQp--eR-Q---H---QIQLLDSLVSCLDAIG-NDCDAAVVPIENLTEGFVSPVVDYLVQ 69 
WP_012242511   4 MAKLITLGSHLNFSSLSSTKFIkelnL-D---V---DISYEHSIDSAFKALL--GADYLVLPIENAIDGYIQRTLDLIYK 74 
WP_011769039   1 MPKIATLGPKETFSDLATQQYLqsqnR-A---Y---EIKYFNSLPETFAAIG-NDCEMGVLPIENLSEGYVQVVLDHLFD 72 
WP_013162671   1 MATIATIGPEGSHAWQAARQYD----P-A---A---ELLLLPSFTDVFAALAAGGATRALLPAHNTREGRNRDFFRLLSG 69 
NP_346859      1 MKKAAVLGPKGTFSEFAVKEYKnkidN-N---I---EMIFCSTISKVVKAAE-EECDIAIIPIENTLDGFVQVTLDLLSK 72 
WP_104936574   1 MSSLALVGTEASLAWQAARKFL----A-T---A---DIRTCPDMASLLAIFASGAVDFALFPVYNTREGEQKQQFRFFDR 69 
6VH5_A        93 ---ADMHIVGEYFLPIHFQLMV-L-PGVrrEEIKTVHSHIHALGQCRNVIRQN--GWKGVIAGDTAGAARLV-A-DVk-d 162
WP_015120568 106 kidPEWRIIDEVTIPITSSLLV-K-TGTkaSNIKQIISHPNALRGVATYLKQNfpEVPLIEVNSTAAAAKLV-S-Ng--d 179
WP_038470792  68 ---GHYHISREIVLEIILSVVS-K-EPn-sENIEQIFATTHSINECYNNLKKEfgKYQRFEVKTDKMALEKL-N-EEt-k 138
WP_100257451  76 ---SGFQVIDQLSLNIQFSFIY-NcPe--lNDIESLFVHPVARSQTSYFLSSMr-DAKVCLSYSNAHSYQLF-L-EKqhh 146
WP_011233302  70 ---RPLHIQAEIRIPVGFQCLA-N-S----AQPQQIWAQFVAAGQCNQCLNEL--GLPVIHTASNALSLDALlAtE---- 134
WP_012242511  75 ---YDYFITHVNELPVDFSLVT-N-E-VslDLVDTIYVQFKAKNQCLNFLESLp-KVKYIITDSNSESLNKL-L-THe-- 143
WP_011769039  73 ---TNLVVISEILLPIRFSFVA-S-C-AnlSELTDLYVQFVAHGQCSEFIDKLg-NIKVHNTQSNIESLLLA-Q-KHg-- 141
WP_013162671  70 h--PRIHWQDNVILPVHLSLGA---PSs-dGTINTVVGRPQFLRQCEEYLAARhpAADLLAAHDLNRTVNDL-L-SSg-r 140
NP_346859     73 ---TNLNIIYELVLPIQFAFAA-N---SkmEEVQRVYAQFKTQGQCCEFLEKHd-EFKIITTESNGQSLKKL-K-EGv-- 140
WP_104936574  70 i--TQGYWVDNVVLYSQISLGVfD-PSQppAELRSVLGTRDALSQSEEYLESHlpHATVITVADVQTALATF-G-REa-r 143
6VH5_A       163 RSMAALAPRLAAD-L--Y-GLDILEENVEDSENNVTRFVVLSKNKqwAA--RP-E-NDer--iVTTFVFRV--R-NVP-- 227
WP_015120568 180 GTTAAVASPNAAK-V--Y-GLQTIATNIQDNN-YETNFWIIARSN--LA--SF-D-PN-----SNHLIISI--K-A-Psg 239
WP_038470792 139 VKRGSVLS-NFEE-LgsY---NVVVSNIRDTKENTNKYAYITRSL--QV---N-GvHN-----KTLIACSP--KfNRT-- 198
WP_100257451 147 GAVGAVIPHYLAQ-A--AdG-HGLMPDVNNVRKNQTRFLILTRPN--ATtrPNiT-H------NVHLALf------RPav 207
WP_011233302 135 KPSAAVVPKHVNC-P--A-SLQILNSNIADNPRNETRFVVLSATS--ET--PEf---DksthwKSSLLLIDd-N-DHP-- 199
WP_012242511 144 KSSAAIIPKHLID-R--H--FLLTIHNIHDDELNHTRFAFIEKHP--TM--PK-D-KEh---lKALLSIQPk-K-DEV-- 205
WP_011769039 142 DGAGAIIPQHALNmA--K-NQTLIRGNVTNYKNNQTRFLVLTDKP--QP--RL-A-EQq---yKTTLVVKNe-K-DSP-- 205
WP_013162671 141 TDFGLIEAEEAIH-H--Y-GLVLREREISP--HNLTRFAILGDSL--PA--AS-G-YD-----ATAVITRPl-K-DRV-- 199
NP_346859    141 LGEGAIVPAYAVKgT--N-KFKCNINNVTDSEGNETRFIVLSKEK--VQ--YE-G-KGy---yKTGIIISDanA-DKP-- 205
WP_104936574 144 QSVAVLDSEERLR-G--M-GLHVLEREIAP--YNRTRFAVVGRTL--AA--PS-G-YD-----ATVFTTEPl-A-DRV-- 202
6VH5_A       228 --AALYKALGGFATNGVNMTKLESYQLGGRFIATQFYADIEG-HPEER----SVQLALEEL-R----FFTKEVRILGVY- 294
WP_015120568 240 -sRIFSETIAKLQKAGFYVVNVNSIPLGESIHSYRYLIRFES-KSQNFnnlkQVKTLLKAM-Q----NSDGEVILLGAY- 311
WP_038470792 199 --GSLYDIIHEFIIRGVNITKILSSPQKTSDDNIIIYIEVDG-NIEDK----LITEALNIV-K----LKSRFISILGSYf 266
WP_100257451 208 knHSPLNYFSAKQHCGINFRSIVPIPSGDGLGRYLYYTEIDA-QSAGQ------RHDLAALf-----EDS-QWTALGGYy 274
WP_011233302 200 --GLLVDSLQVFAKQQINLTSIVSRPAGSQFGDYHFFIDFDG-HLSEP----GVAAALQEL-A----KM-NNIHWLGSY- 265
WP_012242511 206 --GLLYNLLQHFKNLNINLSSIISRPKTDKTSPYHFFLEINT-KLDQ------LSALTTRLaS----DNQLNIKILGVY- 271
WP_011769039 206 --GVLGNIVAAFAEQKVNLTSIMSRPTKSEFGKYHFFIDIDG-HQEDP----DVDRALQQI-M----RQ-HPVTILGSY- 271
WP_013162671 200 --GLLYAMLGEFARRGINLLDMDSEIDP-QSRKLSFFIEMEG-HAEAG----EIRQALKHV-EeeviQEPGSIRIIGTF- 269
NP_346859    206 --GTLWRVLNEFSVRDINLTSIISRPTKKGLGQYYFFIEVDGcYFKDN----RLNEAVEAI-K----HH-SVVKVVGTY- 272
WP_104936574 203 --GVLVDILGEFSRRGISIQDLRTENDV-KTQKLRIYLEVEG-HIQDP----GIAAAVEYI-EnrviQQKGAMRLLGSF- 272
6VH5_A       295 --K----GSDI 299
WP_015120568 312 --Q----R--- 313
WP_038470792 267 --S----K--- 268
WP_100257451 275 qkPtphlRVgr 285
WP_011233302 266 --P----AAAI 270
WP_012242511     -----------    
WP_011769039 272 --I----KASK 276
WP_013162671 270 --P----RVDI 274
NP_346859    273 --Y----KI-- 275
WP_104936574 273 --P----RVDM 277
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