Conserved Protein Domain Family
galactar-dH20

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TIGR03248: galactar-dH20 
galactarate dehydratase
Galactarate dehydratase converts D-galactarate to 5-dehydro-4-deoxyglucarate which is subsequently acted on by GarL, tartronate semialdehyde reductase and glycerate kinase (GenProp0714).
Statistics
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PSSM-Id: 274491
Aligned: 7 rows
Threshold Bit Score: 940.365
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_029240523  18 LTIRVHDSDNVAIVVNARGLPAGTALADGTVLAEGVPQGHKVALADLAEGDAVVRYGEVIGYAVKALPRGSWVNEHAVRL 97  Ralstonia solan...
WP_011105052  11 RYIRLHPLDNVVVVVNDQGVPAGTEFDNGLVTVDNVPQSHKVSTVDLAVGEAIIRYGHTIGYALQPIPRGSWVREDQLRM 90  Pseudomonas syr...
WP_008651306  19 LYIRIHANDNVAIVANDGGLPAGSVFPCGLTLVERVPQGHKVALVDLKKGDAVTRYNVTIGYALQDLPRGAWVNERVIEM 98  Cupriavidus
WP_011038343  11 LSLQAHPQDNVAIVVNDGGAPPGATFQDGMTAIEHIPQGHKIALQALHKGTAVRRLGAVIGTAADDIARGAWVSEQLLEM 90  Xanthomonas cam...
WP_011199874  13 LYIKVNPTDNVAIVVNSNGLPAGSQFEDGVTLIEHIPQGHKVALVDIPKDSEIIRYGEIIGYAVKDIKQGSWIDESLVTL 92  Mannheimia succ...
WP_013056592  12 LYIKVNENDNVATIVNSKGLSKGTVFPSGLELKEYIPQGHKVSLKNFEKGDKIIRYGEVIGAASSAISQGTWVKESYVTL 91  Bacillus megate...
WP_011683504   1 MYIRVNDQDNVGIIVEPEGV---------VTARERIPQAHKMALCDIDAGTPIIRYGQTIGIANRAIANGSWVREELMDM 71  Candidatus Soli...
WP_029240523  98 PSAPALDDLPLATRPDPGLPPLQGYTFEGYRNADGTVGTKNVLGIMTSVQCVAGVTDHVVARIKRELLPRYPNVDDVVAL 177 Ralstonia solan...
WP_011105052  91 PSAPALDSLPMSDAVPEKQAALEGYTFEGYRNADGTVGTRNILGITTTVQCVTGVLDHAVKRIRDELLPKYPNVDDVVAL 170 Pseudomonas syr...
WP_008651306  99 PTAPGLTDLPIGTRVPEPLPPLEGYTFEGFRNPDGSVGTRNILAITTTVQCVSGVVEHAVHRIKTELLPRYPNVDDVIGL 178 Cupriavidus
WP_011038343  91 PTAPELAALDLTPQPPAAAAPLDGYTFQGYRNRDGSVGTRNILGIMTSVQCVVGVLGHAVARIRAELLPKYPNVDDVVAI 170 Xanthomonas cam...
WP_011199874  93 PKAPPLETLPLATRKAPKLEPLEGYTFEGYRNKDGSVGTKNMLGITTSVHCVAGVVDYVVNIIEKELLPQYPNVDGVVGL 172 Mannheimia succ...
WP_013056592  92 PDPPILEKLPLATKVSAPLSPLEGYTFEGYKNTNGSVGTKNILGITTSVQCVVGVLDYAVKKIKTELLPSYPNVDDVVAL 171 Bacillus megate...
WP_011683504  72 PAAPPLEELALATEIPVKLPPLDGYTFEGYRNSDGSVGTKNILGIATTVQCVAPTVDYAVRRIQAELLPRFPNVDGAVAV 151 Candidatus Soli...
WP_029240523 178 NHAYGCGVAINAPAAIVPIRTLQNLALNPNFGGEVMVIGLGCEKLVPERLVPETLAPggripievaGTADSPVLRLQDEA 257 Ralstonia solan...
WP_011105052 171 THSYGCGVAITATDAYIPIRTVRNLARNPNLGGEALVIGLGCEKLQAGQVMHEDDSSv--------DLSEPWLYRLQDSS 242 Pseudomonas syr...
WP_008651306 179 EHTYGCGVAIDAPDAIVPIRTLRNIALNPNFGGTAMMVSLGCEKLQPERLMPPGTIPiqt----gaGEVQVGVVCLQDDK 254 Cupriavidus
WP_011038343 171 NHVYGCGVAITAPEAIIPIRTLRNIARSPNFGGQALIVGLGCEKLAPERLLPDDASA-----------DDSGIYRLQEAS 239 Xanthomonas cam...
WP_011199874 173 NHLYGCGVAINAPAAIVPIRTIHNIALNPNFGGEIMVIGLGCEKLQPQRLL-EGTVDty-----piELKDATIMSLQDER 246 Mannheimia succ...
WP_013056592 172 THNYGCGVAINAPDAIIPIRTLQNLSIHPNFGGEVLVVGLGCEKLLPERLSPQEISG--------------NITRLQDHA 237 Bacillus megate...
WP_011683504 152 THSYGCGVAIDAPGAAVPIQTLKHIGLHANMGGAPMIVSLGCEKLQPARLFGSELPI----------LGEANVIRLQDER 221 Candidatus Soli...
WP_029240523 258 FdGFTGMVEAILEMAERRLAQLNTRRRETCPASDLVVGVQCGGSDAFSGVTANPAVGFAADLIVRAGGTVMFSEVTEVRD 337 Ralstonia solan...
WP_011105052 243 H-GFNEMIEQIMELAETRLKKLDVRRRETVPASELILGMQCGGSDAFSGITANPALGYASDLLLRAGATVMFSEVTEVRD 321 Pseudomonas syr...
WP_008651306 255 HvGFASMIDSIMAMAETHLQTLNARKRETVPVSELVVGVQCGGSDAFSGVTANPAVGFATDLLVRAGATVMFSEVTEVRD 334 Cupriavidus
WP_011038343 240 L-GFADMVGSIMQMAEERLRHLDTRRRETVPASELVVGMQCGGSDAFSGVTANPGLGIAADLLVRAGATVMFSENTEVRD 318 Xanthomonas cam...
WP_011199874 247 HvGFEAMIKEILETAKQHLEKLNRRKRETCPVSDLVVGGQCGGSDAFSGVTANPAVGFAADLLVRAGATFMFSEVTEVRD 326 Mannheimia succ...
WP_013056592 238 --GFKQMIAAIIEMAEEKLIKLNSRTRVTCPVSDLTLGLQCGGSDAFSGVTANPAVGYAADLLVRAGATVLFSEVTEVRD 315 Bacillus megate...
WP_011683504 222 --GFAASVSAIMEAAERRLAVLNRRQRQTVPASELVVGLQCGGSDAFSGVTCNPAVGFAADLLVRAGATVMFSEVTEVRD 299 Candidatus Soli...
WP_029240523 338 AIHLLTPRAIDADVGRALLREMAWYDSYLSGGQTDRSANPSPGNKKGGLSNVVEKALGSIVKSGSSPIVDVLGPGEKVRR 417 Ralstonia solan...
WP_011105052 322 AIYLLTSRAQDQDVAQALVREMDWYDRYLAKGEADRSANTTPGNKKGGLSNIVEKSLGSIVKSGSSAINGVLGPGERVNS 401 Pseudomonas syr...
WP_008651306 335 GIDQLTARAATPEVAEAMIREMDWYDRYLDRGRVDRSANTTPGNKKGGLSNIVEKAMGSIVKSGSAPISGVVSPGEKVKQ 414 Cupriavidus
WP_011038343 319 GIHLLVPRAANAEVAKALVREMAWYDAYLARGQADRSANTTPGNKKGGLANIVEKAMGSIAKSGSSPINGVVPPGERVKG 398 Xanthomonas cam...
WP_011199874 327 AIHLLTPRAETVEVGKRLLEEMKWYDDYLDMGQTDRSANPSPGNKKGGLANVVEKALGSIAKSGSSNIVEVLSPGQRPTK 406 Mannheimia succ...
WP_013056592 316 AIHLLTPRTINKEVGQSLIKEMKWYDQYLKRGEADRSANPSPGNKKGGLVNVVEKALGSIAKAGTTPIVEVLSPGEKPTK 395 Bacillus megate...
WP_011683504 300 AIHLLTPRAETTEVARALIREMRWYDEYLARGGADRSANTTPGNKRGGLNNIVEKALGSIVKSGSTAIRAVASHGEKVTA 379 Candidatus Soli...
WP_029240523 418 KGLIFAATPASDFVCGTLQLASGMNLQVFTTGRGTPYGLSMAPVIKVSTRKALSERWHDLIDLDAGRIATGEASIADIGW 497 Ralstonia solan...
WP_011105052 402 KGLIFCATPASDFVCGTLQLAAGMNLHVFTTGRGTPYGLAMAPVVKVSTRTELAQRWPDLIDIDAGRIATGRASIEDLGW 481 Pseudomonas syr...
WP_008651306 415 KGLIYAATPASDFICGTLQLAAGMNLHIFTTGRGTPYGLAEVPVIKVATRSDLARRWHDLMDVNAGRIATGEATIEDVGW 494 Cupriavidus
WP_011038343 399 RGLQYCATPASDFVCGTLQVAAGMNLHVFTTGRGTPYGLGMVPVIKVATRTELAQRWSDLMDIDAGGVASGAKTLDQLGW 478 Xanthomonas cam...
WP_011199874 407 KGLIYAATPASDFVCGTQQLASGITVQLFTTGRGTPYGLKAVPVIKLATRTDLANRWFDLIDIDTGTIATGKETIEQVGW 486 Mannheimia succ...
WP_013056592 396 KGLIYAATPASDFVCGTLQLASGMNMHIFTTGRGTPYGLAMAPVLKVSTRSSLTEQWHDLIDLDAGRIAQGEATIEEVGW 475 Bacillus megate...
WP_011683504 380 KGLVFAATPASDFICGTQQLAS-MNLHVFTTGEGSPYGLALVPVIKVSSRTALAEKWADLIDLDAGRIATGQATIAEVGW 458 Candidatus Soli...
WP_029240523 498 ELFRLILDVASGRKQVCADRLGLHNALTLFNPAPVT 533 Ralstonia solanacearum
WP_011105052 482 ELFHFYLDVASGKKKTWTEHYRLHNDITLFNPAPIT 517 Pseudomonas syringae group genomosp. 3
WP_008651306 495 ELFHLMIDVASGRKQTWAEHHKLHNALALFNPAPVT 530 Cupriavidus
WP_011038343 479 ELFQRYLDVASGQR-TWTEQHRLYNDLALFNPAPIT 513 Xanthomonas campestris
WP_011199874 487 RIFHEILDVASGRKQTWSDKWGLYNQLSVFNPAPVT 522 Mannheimia succiniciproducens
WP_013056592 476 ELFHLIIEIASGHKKTWSDYWGLHNDLCLFNPAPLT 511 Bacillus megaterium
WP_011683504 459 ELFRMMLEVASGRRKTWAEKWGLGNALAPFNPGPVT 494 Candidatus Solibacter usitatus
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