Conserved Protein Domain Family
BrkB

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COG1295: BrkB 
Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase) [Function unknown]
Statistics
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PSSM-Id: 440906
Aligned: 942 rows
Threshold Bit Score: 72.9772
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_076928335  49 NilY----D-----AIKTVMLTVRNVQELDIAASARSLTYRTLLSIVPLLAIIFAI----ARGFGIen-----iMESSIF 110
WP_083525859  33 KliRqlssRvftlpLVGVLLSAVRNYVLHQSANQAGSMAFSTVLAMFPLVLLLSAG----AAFIGSp------gDAAALV 102
WP_082938475  11 RwvRrvavRt---pVLGVLLLAIRNYVLHQSANQAGSMAFSMVLSMFPLLLLLSAG----AAYIGSp------gDAAALA 77 
WP_108881317   1 --mV----Q-----IAKTLWRATTKFVDDGGSAIASNVALSLLLSLFPFLMLVTSL----VRIWGNp------aLVDEVF 59 
WP_011450602   5 Kv-L----T-----FFKCICKAVIDFRDHDGMEYAGYLSFIVLLSMFPFFVFFNAL----TSSIVSvldk-dqfLYTRLF 69 
WP_013951083   6 Ki-I----T-----FIKIIYQSLINTINHDGIEHAGYLSFLLMLAIFPFLVFFTAI----IGTLSSlvd---ipLVTTLT 68 
WP_005611294   5 qnlM----Q-----AIRILRRALGRFGRKNAWVLSSHIAMSMMMALFPFVLFTVALsgaiASLFSHr------vVVDDVV 69 
WP_046477412   2 Q-------------QHQPFLKAIYELYEHSGFSMAGAVAFSFVVSLFPFCIFLTGL----AGLIGSp------eLAGKAV 58 
WP_011451788   1 --mK----R-----TFAVLKISLYNMLYHGGSEYAGYLSFLLLLSIFPFLFFFTAV----AGYTANivgassyeITRKLL 65 
WP_052646329   4 Rl-K----T-----LLRCFYKAIYNTVYHEGVEHAGYMAFLLMLTIFPTLVFFVAL----VGFFGKq------nLSELLV 63 
WP_076928335 111 NfMLGS--RP-AdeivvatpepgtdstititagigavdtiyqaseeitvnsalspagageeevsaegrtrefLNLLFQII 187
WP_083525859 103 S-RVVDyaPPlV------------------------------------------------------------RSAMQPVI 121
WP_082938475  78 G-RVVEyaPPlV------------------------------------------------------------RSALQPVV 96 
WP_108881317  60 N-LVLEhwPAdS------------------------------------------------------------EKAITDQV 78 
WP_011450602  70 D-VLSGelPHdT------------------------------------------------------------MDALLPRI 88 
WP_013951083  69 N-LIINspWAsF------------------------------------------------------------IDSLKPRI 87 
WP_005611294  70 D-LVFGswPQsV------------------------------------------------------------AEPITREV 88 
WP_046477412  59 T-QLFQvlPRdV------------------------------------------------------------AQALAPQV 77 
WP_011451788  66 S-VFIEnvPEnI------------------------------------------------------------IEGIMPYI 84 
WP_052646329  64 N-LILEssWAnF------------------------------------------------------------IEALKPRI 82 
WP_076928335 188 DNSLEEaKgGGVFAGIGILLFLYTILVLFNDIERNLNKIWQINKG---RAIGRKVTDYTAMVLFMPVFFILVNALN---- 260
WP_083525859 122 NQVLAQ-R-SQALLAIGLFVTLWTASSGMQAVRTALNRAYGIERG---LPFWRARLKVTLFTVVVGGGILATFSSVivmp 196
WP_082938475  97 NQVLAQ-R-SQALLAIGLFVTLWTASSGMQAVRTALNRAYAIERG---APFWRARLKVILFTLIVGGAILAIFSSVivmp 171
WP_108881317  79 KVMVAQ-T-PNEFFSVSTLVALVLATNGIENARDGLNRAYRVTET---RPFWWRRLQGAVFVIIGAFGLILAAITLigtp 153
WP_011450602  89 EEILSG-P-PQSLLTVAIGGVIWTASSVIEGIRHVLNKALRVSAP---PPYILGRMFSILQFLIIVAVMMLSVLFAvlvp 163
WP_013951083  88 IEITTL-P-PQSFLTIAIISAIWTASSIFEGIRTTLNRAYHVKNP---PAYLLRRLFSILEFIIVIIILAVAICTLiiip 162
WP_005611294  89 YAVLET-S-GTGLMTLGGVLALYFASNGVDAIRIAMLRAYGQEET---RPFWKHRLISLGLVIMGGAGLLLTAVFElflp 163
WP_046477412  78 VSIMSS-T-RIDLLTVGGGIALFFATSAIETLRAALNGAYRVRET---LTYPLCLLRSMLFVLILALSMLVLTWAVivgp 152
WP_011451788  85 KEILEG-P-THGLLTLTILGAIWTASSIVEGLKAAVNKAYNFGTEtlvSEYILRRFVSVIQFLLISIIILIFLLFp---- 158
WP_052646329  83 IEITSS-P-PQSLLTIAIISALWTASSIFEGLRTILNKAYKITTT---ATYLKRRLISFLEFAGLMMITIILLVTLlivp 157
WP_076928335 261 ILSYP-QND-T--LKiiYILYPF----IPRLLDIVPFVVMILLFTALYKF-LPNTKVKFMNALIAGVVAGIAFQFFQMLY 331
WP_083525859 197 YVWQA-LEQnMg-VG--RETVWL----RNSVRYGSAFAVLVVLYALLYGW-LPDIRQRLGTVLPGAVVGAALWVGAAATL 267
WP_082938475 172 YVWEA-LEKsVg-KG--RETLWL----RNSVRYGVAFPVLVVLYALLYGW-LPDIRQRIRTVLPGAVVGAALWVGSAATL 242
WP_108881317 154 LVWSY-LVNkLawL---EPFSFT----VAVTKYALAIAVLTLTLFAFHRF-LPDGKRTIRTTFPGIALTISGIIVGSQLF 224
WP_011450602 164 IIFEV-Vgr-----------------hWEFLRFVVSKVVLFIAVSWIYFM-VPNVRQNILVVLPGAAVVTATWTLTSMAF 224
WP_013951083 163 AMWDF-LEKhIv-IPd-aQIISLidkdLEVLRSTILYLFSIVFVSYLYYS-LPNKKQKFTKILPGAVLVLFCWAAFSKIF 238
WP_005611294 164 LGARF-VARfFpdL---DFLRGW----EHGANGLVVAVIPVAAVFLYHLVlLP-RRETVRHILPGAVVTLLLWWAAGTGF 234
WP_046477412 153 AVAARfEPSwVksL---LDSTWL----AVGFRYGLAAIVIATQLLALHLW-LVAGERSLADVLPGILLSTLLWIGAGAMY 224
WP_011451788 159 TVYPL-LTKnV-------SFLHLlkrpSWLPYSTVTTCCIFCFVSALYIF-FPKEKQKFTDVVPGSIMVVSLWILTSIAF 229
WP_052646329 158 WIWNY-VYMfVe-IYd-nPLINFigkpTHMLRYLILILFGFILVSGLYYY-LPNRKMKFTLTFPGTVSVLLGWAISSALF 233
WP_076928335 332 LSGQMWITRYNAIYGTFAAIPLMLLWIQMSWFIVLIGAEVSY---AAQNVRKFSFE 384
WP_083525859 268 SYTLRSAGKLALLYGSFAGVVATLVFLYVTASTLIYGAEVNA---VIRERTDGNPE 320
WP_082938475 243 SYTLRSAGKLALLYGSFAGVVATLVFLYISATTLIYGAEVNG---VMRQRLTAESE 295
WP_108881317 225 ALYLQTIANYTALYAGLAGTMIAIVYLYGLSALILFGAEFNT---ALTERERAPD- 276
WP_011450602 225 SWYLSTFQVLKTIYGNLTGIIAAMLFFYILSIFFIYGAELNY---RLSNRHS-SVH 276
WP_013951083 239 KYYISYFPQINMIYGSIAGIIISLLFFYFCSLILIYGAEFNY---LVELEFkekk- 290
WP_005611294 235 ALYVSSFASYSATYAGLAGAMAALIFLYLNAAILILGAEING---VLQTDRLAEEE 287
WP_046477412 225 SYYL-EFSDYSRFYAGLSQLMVAMIFFQVTAVIIILGAELNR---GLIELRKLSAN 276
WP_011451788 230 SFYLHSFAQMNIIYGSIAGIIVVMLYFYLLNLCFIYGAEINAlnkRISQK------ 279
WP_052646329 234 RLYLSYFPSINIIYGSIAGVIIALLYFYICSLIFIFGAEFNY---QVEKNFGLNVN 286
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