4LFY,1XGE,5VGM


Conserved Protein Domain Family
PyrC

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COG0418: PyrC 
Dihydroorotase [Nucleotide transport and metabolism]
Dihydroorotase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Statistics
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PSSM-Id: 440187
Aligned: 239 rows
Threshold Bit Score: 468.808
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4LFY_A        26 SPATLSLARPDDWHLHLRDGDMLAAVLPHTARQFGRAIVMPNLKPPVTTTAQAQAYRERILAALPA---GMTFEPLMTLY 102
WP_011650283   1 -MQSITIRRPDDWHLHLRDGAMLEGVIADTSRTFARAIIMPNLVPPVVTSADAKAYRERILKALPD---SHRFQPLMTLY 76 
WP_011580814   1 -MKTLTIRQPDDWHLHLRDGSVLQAVAEHSAAHFARAIIMPNLVPPVVTTRDAAAYRERILAALSE---GSAFTPLMTLY 76 
WP_007091884   5 SVNRITLRRPDDWHLHLRDGAMLEGVIGETSEHFARAIIMPNLVPPVVKTEDAIAYRDRINAVIPQ---GHDFTPLMTLY 81 
WP_015273070   1 -MQSLIISFPDDWHLHLRDGEILRSVITDSSQHFKRALIMPNLIPPIITISDAKAYKKRIIDCLPD---NHHFEPLLTLY 76 
WP_018064379   1 -MNSLTIRRPDDWHLHLRDGAMMEGVIGDSARHFARAIIMPNLVPPVVTALDAEAYRNRIREAVPA---GMSFTPLMTLY 76 
WP_088917821   1 --MQITLTQPDDWHLHLRDDDMLSAVIGSTAQHFGRALVMPNLVPPVITGHDARQYRTRIEQALQErapGSSFNPLMTLY 78 
WP_113156113   1 -MKSLTIRRPDDWHLHLRDGAVLEAVLPHSSDDFARAIIMPNLVPPVVTVKDALAYRERIMAAKPE---GHDFTPLMTLY 76 
WP_117413552   3 AVTELEIRRPDDWHLHLRAGAMLDGITPSTTADFARAIIMPNLVPPVVTTADAEAYRTRIMAAVPQ---GDTFEPLMTLY 79 
WP_109759769   1 MTDRLTLRRPDDWHLHLRDGAMLDGVLPWSARHFARAIVMPNLVPPVVTGRDAAAYRDRILNALPE---GMTFEPLMTLY 77 
4LFY_A       103 LTDNTPPDEIRRARESGFVHGVXLYPAGATTNSDHGVTDLAKCAKTLEAMQETGMPLLVHGEVTDASIDLFDREKVFIDR 182
WP_011650283  77 LTEHTSPDDVEEGKNSGLITAVKLYPAGATTNSHGGVRDMEKAMPVLERMAKIGLPLCVHGEVTTPEVDIFDREAVFIDT 156
WP_011580814  77 LTESSCADDIEAGFRSGLIKAVKLYPAGATTNSQSGVRNIEAVYPVLERMAKIGLPLCVHGEVTDPAVDIFDREAVFIER 156
WP_007091884  82 LTEGTNPDDVEEGYKSGVITALKLYPAGATTNSASGVRDFDKAMPVLERMASLGIPLCVHGEVTDPEIDIFDREAVFIDR 161
WP_015273070  77 LTEETNPDDMEEGARAGVIHAIKLYPANSTTNSFHGIHNIDKIMHLLERMEKIGLPLCIHGEIVNTDVDIFDRETVFIET 156
WP_018064379  77 LTETTEPADVASAFSEGLIKAVKLYPAGATTNSASGVRNIDNAMPVLEKMAEIGLNLCVHGEVTDKDVDIFDREAVFIET 156
WP_088917821  79 LTDTTDAADVVQAAADGTILAVKLYPAGATTNSASGVTDLQKVMPVLEAMAANNIVLCVHGEVTHADVDIFDREARFIET 158
WP_113156113  77 LTEQTDAEDVAAGYRDGHITAVKLYPAGATTNSQSGVRDLLKVQPVLERMAEIGLPLCVHGEVTDASIDIFDREAVFIET 156
WP_117413552  80 LTGVTDPDDVAAGAASGLIKALKLYPAGATTNSESGIRDIETAYPVLERMSEIGLPLCMHGEVTDPDIDIFDREAVFIDR 159
WP_109759769  78 LTEDTDPADVAKAAETGLVKAVKLYPAGATTNSASGVRDFDRVRPVLERMAATGLPLCVHGEVTRPEIDIFDREAVFIDE 157
4LFY_A       183 VMTPLRRDFPGLKVVFEHITTKDAADYVRdadAAPGLLGATITAHHLLYNRNALFVGGIRPHYYCLPVLKRETHRVALVE 262
WP_011650283 157 VLDPLRQRLPELKVTMEHVTTSDGVDYIK---AARGNLAGSITTHHLIINRNAILVGGIRPHYYCLPVAKRENHRLALRA 233
WP_011580814 157 VLQPLRRRLPELRIVMEHVTTKDGVDFAL---SQDENVGATITTHHLIINRNAILAGGIRPHYYCLPVAKRESHRLALRA 233
WP_007091884 162 VLDPLRKRLPELRVIMEHITTEDGVEYVK---ANDRNLGATITTHHLIINRNAILVGGIHPHFYCLPVAKREKHRLALRK 238
WP_015273070 157 VLDPLRKRFPGLKITLEHLTTSNSIDYIL---NSKENLAGSITAHHLIINRNALFINGINPHYYCLPIAKREKDRLALRK 233
WP_018064379 157 VLDKIRWRLPELKITMEHVTTRDGVDYIK---GARKNLAGSLTTHHLIINRNDILVGGIRPHYYCLPVAKREEHRKALVA 233
WP_088917821 159 VLEPLRKSLPELRIVMEHVTTRDGVDYVS---ANPKNLAATLTTHHLMINRNHLLVGGIRPHYYCLPIAKREEHRLALVK 235
WP_113156113 157 VLQPLRERLPELKVIMEHVTTKNGVDYVQ---GAEKNLAASLTTHHLIINRNAILAGGIRPHYYCLPVAKREEHRLALRK 233
WP_117413552 160 VLIPLRARFPDLRIVMEHVTSRQGVDYVR---SQEKNLGATLTVHHLIINRNAYLVGGIKPHFYCLPVAKRETHRLALRE 236
WP_109759769 158 VLDPIRRATPGLRVVMEHITTSEAAAYAA---SGGDDLAATITVQHLMLDRNDMLVGGLRPHFYCLPILKRGTHRPKLLE 234
4LFY_A       263 AATSGNPRFFLGTDSAPHARDAKETACGCAGCYTALHALELYAEAFDTAGALDKLEGFASFFGADFYGLPRSAETVTLRR 342
WP_011650283 234 AAVSGDPRFFLGTDSAPHVDPLKECACGCAGIYTSVNTMSCLAHVFEQEGALERLEAFVSLNGPAWYGLQPNEERITLSR 313
WP_011580814 234 AAISGEGRFFLGTDSAPHLDPLKECACGCAGVFNAPNTMACLAHVFEEEGALDRLEAFTSLNGPAFYRLPPNEKRITLRR 313
WP_007091884 239 AATSGDVRFFLGTDSAPHTDDRKESACGCAGIFTANNTVQLLAHVFEEEGALDKLEGFASVNGPQFYGLPLNGDKITLEK 318
WP_015273070 234 AAVSGDSRFFFGSDSAPHIDSMKECSSGCAGIYTAINALSCLAQVFEQENKLENLEAFISSNGASWYKMPLNTEKITLVR 313
WP_018064379 234 AATSGDKRFFLGTDSAPHVDPAKECGCGCAGIYTAPNTMSCLAHVFENEDALDKLEAFASLNGPAWYGLKPNEETITLVK 313
WP_088917821 236 AATSGDARFFLGTDSAPHTRSSKESDCGCAGVFNAANTMVCLASVFEEAGALDKLEAFASLNGPQWYGLQPNSATMTLGK 315
WP_113156113 234 AATSGDSRFFLGTDSAPHLDPAKESACGCAGIYTSINTMSCLAHVFEEEGALDRLEAFASLNGPAYYGLPANEDTITLER 313
WP_117413552 237 AATSGDSRFFLGTDSAPHADPAKESACGCAGIFTAPTAMSCLAHVFEQENALDKLEAFVSLNGPAYYGLPVNEERLRLVR 316
WP_109759769 235 AATSGSPRFFLGTDSAPHPTDRKEAECCAAGCFTAPVALSCLAEVFDEAGALDRLEAFVSENGARFYGLPRNEGTVTLEK 314
4LFY_A       343 --EPWELPREIFAGETPVVPLRGGETIGWKLA 372
WP_011650283 314 qaEPVVFPARIETGAGPVTVFDPMFPLHWQVV 345
WP_011580814 314 ydEPLEMERKVSVGDEAITVFDPMFPIHWKVE 345
WP_007091884 319 rdAAATFPARIETGEGPVTVFDPGFPIYWHYA 350
WP_015273070 314 hhSPIDFPSKKQTNMGSITVFNPNMPLYWKVK 345
WP_018064379 314 rdEPVEYPEKRETGAGPVTVFDPKFPLYWDVE 345
WP_088917821 316 teSAMPVPAPVAIGDEWVMPFDPARPIYWQVL 347
WP_113156113 314 rdEPVEFPHSVYSSDGTITVFDPMFPIHWAVV 345
WP_117413552 317 geAPLEWPKRVSTGAGPVTVFDPGFPLFWRVE 348
WP_109759769 315 g-DPLEIPVAVETGAGSVTVFDPGRPLHWRVV 345
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