6IJF


Conserved Protein Domain Family
Tae4

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pfam14113: Tae4 
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Type VI secretion system (T6SS), amidase effector protein 4
Tae4 is a new form of toxin-antitoxin system protein for a type VI secretion system, T6SS. T6SS has roles in interspecies interactions, as well as higher order host-infection, by injecting effector proteins into the periplasmic compartment of the recipient cells of closely related species. Pseudomonas aeruginosa produces at least three effector proteins to other cells and thus has three specific cognate immunity proteins to protect itself. Tae4, or type VI amidase effector 4, in Enterobacter cloacae has a cognate Tai4 or type VI amidase immunity 4 protein. The immunity protein is Tai4, pfam16695.
Statistics
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PSSM-Id: 433727
Aligned: 27 rows
Threshold Bit Score: 87.8112
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6IJF_C               45 HNTCAIRVSIAFVKS--GINIVPSS-Hr-----------iQKGPYAGKG------IEVNMRRLATLMKRT-SylgePDPY 103
XP_001745837         33 ANYCAIRLSHGLMAS--GHKITQPS---------------DFRDREGNK------YIIRVATMQSYLSKVlGt---PKEV 86 
XP_001628322         60 ANTCAIRLSYALIHS--GHEISIEKgQfnwseeratratgRYKDAK---------YIIRVATMRKYLEKVlGp---AKML 125
XP_002589642        148 KNTCAMRVSYAITKS--GMTMEVPDeCr-----------eNWAGVRDRNrn---pYFIRVATMCCYLQETiGa---PAIT 208
XP_002602596         82 KNTCTMRVSRALTHA--GKEIVPGSc--------------NWSGVRDSKnr---pYIIRVATMRCYLENQyGq---ADVT 139
jgi:Sta7437_2870    503 DNTCAIRMSKALNYSlpDKKIPFIN---------------KDVTIKGGDnl---rYIFRVKDFINYITGKfGk---PNIQ 561
BAM32784            117 SNTCAMQVSYALNYG--GMPLHTEIkVk------------EYNSMYGRGek--ylYILGADYMGRYLNDKwGka-eISIT 179
BAM32787            117 SNTCAMQVSYALNYG--GMPLHTEIkAk------------EYNSMYGRGek--ylYILGADYMGRYLNDKwGkaevAIEP 180
wkYale:SALWKB2_1086  66 KNTCAIRMSYILNRG--GLKIKYE----------------QDQTVSGFInekkfwFYYRVKDLINFLTNEwGk---PDIK 124
jgi:Fraau_1588       48 VNTCAIRMSYILAQA--GMPIPHL----------------SGKTIPGRGhh---qYFYRVKALRSFLQQRwGh---ADVQ 103
6IJF_C              104 TPATAR----NGIGARNGVVAFNNI------PGYTGGGHIDLVRG----------GS--EATQCA--SAcyyNSE----- 154
XP_001745837         87 TSk-------QAIAGRRGIVLFTI-------AYSDATGHVTLWNGsdl----rhpAG--TVDEQ---FR---KST----- 135
XP_001628322        126 SKNk------STYKGSKGIIVFQDCp-----KFTTATGHVDLYDG----------SR--CVNKCF--FD---QCN----- 172
XP_002589642        209 GKNq------ADYAGHQGIIVFKDC------DFETATGHVDLWDG----------AD--CCGQCY--FD---KCK----- 254
XP_002602596        140 GTSe------SAYRGHQGIIVFQDC------GFATATGHVDLWDG----------SG--CVGRCPgyFS---RCT----- 187
jgi:Sta7437_2870    562 VEIVNNvldkSSLKDKQGIIVFEVN------EWTNATGHATLWNG----------ID--CADKCY--FD---EAN----- 613
BAM32784            180 ATDSGKtaalEQIKDKKGIVVMKGNy-----------sHTTLWNGskfvdvengma--------------rnyyltnigt 234
BAM32787            181 KSNDERkltfNNLQGNTGIAVIKGRhfinqkFSSNFS-HTTLWNTndfvdvqnktnynylleliwndSF---GNThiyhs 256
wkYale:SALWKB2_1086 125 IDRPTe----KDVEGKKGIIIFET-------DFSDATGHATLIKGaqlidgtrtaAS--CYDHCY--FC---SQGyn--t 184
jgi:Fraau_1588      104 LNQPRNg---LGLSGKQGVIIFGVS------GWGDASGHASLFNG----------SS--CYDKCY--FN---SPGakyqt 157
6IJF_C              155 -TIWFW 159
XP_001745837        136 -KTFFW 140
XP_001628322        173 ---NIH 175
XP_002589642        255 -DISLY 259
XP_002602596        188 -DIRLF 192
jgi:Sta7437_2870    614 -KISLW 618
BAM32784            235 aKLELW 240
BAM32787            257 sNFQFW 262
wkYale:SALWKB2_1086 185 sKAHFW 190
jgi:Fraau_1588      158 rDAVLW 163
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