Conserved Protein Domain Family
CoxL

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COG1529: CoxL 
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Statistics
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PSSM-Id: 441138
Aligned: 696 rows
Threshold Bit Score: 193.909
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_124692218   1 MsrrgflkaiavggvtvwiaplysaafgalfeerilrgaqWNpaDGHTRFRIDGHEKVVGGKVFARDI-RaadM-PHwpk 78  
WP_014784746   1 Mfpape-----------------------------lsansTTp-VGRNVVRKEGMGKVLGRAQYIDDL-V---L-PD--- 42  
WP_011218648   1 M---------------------------------------------DTVNTRFKLAEATGEAKYIADR-H---Y-EG--- 27  
WP_013386593   1 -----------------------------------------Md-ISKKIIRVDAEDKLLGKSKYIGDI-E---F-EN--- 30  
WP_014488376   1 Met------------------------------------lIKe-LKNSVARVDALDKITGKTKYLNDI-D---FgKE--- 36  
WP_110138662   1 Mhndd--------------------------------rfgTTl-LKDAPLRKDGTEKVRGTARYVADI-G---Y-PG--- 39  
WP_066747123   1 Mse------------------------------------eFRi-IGKSLPRFDGPVKVAGEVKFLEDI-E---I-PG--- 35  
WP_050434681   1 Mats---------------------------------ptpTPt-VGVSVPRTDGAAKVTGAARYVDDLpP---M-PG--- 39  
WP_006928879   1 Mk--------------------------------------pNp---KD-FRVDARSKLRAEARYIRDE-Q---I-AG--- 30  
WP_011640549   1 ----------------------------------------MGn-ISNPVKRFDFDEKVDGRAQYCADI-K---L-EQ--- 31  
WP_124692218  79 qQSHALILRATQADRTYAGFDLASLGDDLKPDRVVTAEDLARDKlafpgfyGDDMLLPAGKTPAYLGHAVAILIFHDFAR 158 
WP_014784746  43 -MLHGATVRSTIARGRITNIIFSPTIDWSEFV-IVTARDIPGKNtiv--hlAEDHPCLADGFVNHPEEPILLIAHANKAV 118 
WP_011218648  28 -LLEGRFFRSSCSRGVIKAVYVPE---LPEGYHLFGAKDVPGHNvlp--ivEIDWPAFAEKEVRYIGQVIFLLVGPVPDV 101 
WP_013386593  31 -MLFAKTVRSDRVRAKIKSIKY-P--KLPKGYFIVDKNDVPGLNkvk--aiENDQPFFADGVVNYIGEPIALVIGESKYK 104 
WP_014488376  37 -VLHAKIVHSTKARAKILKINIPE---LPEGYSIIDYRDVPGKNaat--miISDWRPFADDNVRYIGETILLIVGPDKNV 110 
WP_110138662  40 -MLHAATLRTCLPGGTVVSISFDDHVPWSEYVVV-TAADIPGINavk--miETDQPVLVETRYRHAGEPVVLVAHPDPQA 115 
WP_066747123  36 -CWLGGVVRSEVPRGVVRKIETLPAFAETGAV-LVTAEDIPGENyva--ivRSDYPALAAPAVNYATQAVALVAAPDAES 111 
WP_050434681  40 -EIFGRTIRSTLPHGILRGIRLDPDFDWSDV-TVVTAADVP-VNvvy--viAEDQPVLAADKILHAYEPVALIACPDRLK 114 
WP_006928879  31 -LWCGVTLRSPHPRARILSIDLDPQFDWNSV-TVVTAKDVPH-Nyva--iiEKDMPVLAKDMVNYVGEPVALFAAPTQEL 105 
WP_011640549  32 -MLYAKTLRSEKARAKIASIEIPH---LPPGYFIVDQNDIPGKNivp--ivYEDQPFLAPNRVNYIGEPILLVVGPDKPT 105 
WP_124692218 159 YQLARGRLRaardvIRYG--AaTgP--LDrePwGVFryvRvgGAsPddedaysslKDsplfpteKktlIwpsTKpEdSld 234 
WP_014784746 119 LHHAIASIQ-----IDYE--A-M-PavFT--IeESE---Aq-KTii--------wGDd------N---Tf-kSY-LmE-- 162 
WP_011218648 102 IEQLLQQIK-----VEYS--P-L-TpaYT--IeQSK---AliDGai--------hSTd------N---Vf-dTH-AlT-- 146 
WP_013386593 105 ILDLISQIE-----IEYE--D-L-EaiYT--IeDGL---Kt-SN-Pi-------fGVd------N---Cf-aDY-HyS-- 148 
WP_014488376 111 VYDIAEKVT-----IEYE--D-L-EpvLN--IeDSK---KllGG-Pi-------yGDd------N---If-iSF-KaG-- 155 
WP_110138662 116 LARALAAIH-----IEERpcA-A-PpvFT--IdEAL---Rl-DT-Rri------aPD-------N---Vy-rDY-LmE-- 161 
WP_066747123 112 LKRAMAAVV-----VEIE--P-L-PpiFT--VeESA---Ar-KEli--------wGEd------N---Ci-dHY-HtE-- 155 
WP_050434681 115 LDRAARAIT-----LDVE--P-L-PpvLE--IaDAL---Aa-KQvi--------wGEd------N---Vf-kRY-LiT-- 158 
WP_006928879 106 AEEALKHVT-----VKYE--P-L-PfiDD--PlKAE---Hs-EIkl--------yGSn------N---Vf-kEI-HiE-- 149 
WP_011640549 106 ILDILKKIK-----VNYE--E-L-KpvLS--IaEAQ---El-QE-Eyi------fANk------P---Cf-vEY-AyS-- 150 
WP_124692218 235 aRGmr---aaEq----IGAELA-AppaDwLVMKRRYTTQSIDTAALEPDNANCWYDPatRSLHMVLATQSPQEVAEAAAK 306 
WP_014784746 163 -KG-------D-----VDAAFAaA---D-YIVEAEYRTGAQEQLYIENNGCIAEWSDt-DGITVHGSMQCPYYLHHALML 224 
WP_011218648 147 -KG-------D-----IDEGFAqA---V-TIIEETCSTGYQEHIYLETQGVVGYPQd--GKVVIEGSMQCPWYVHHCMAV 207 
WP_013386593 149 -KN-------S-----LEEVKSkA---K-YVISGEYKTGYQEQMYLEPQGVVGIYKn--GKVEVHGSMQCPYYIKGAVEQ 209 
WP_014488376 156 -YG-------D-----VDEAFKkA---K-TIIEETYHTPYQEHLYMEVNGTVGVWEn--DGVTLYSSTQCPYYVQKAVAP 216 
WP_110138662 162 -KG-------S-----VMDAENgP---C-HVFEGEYRTGAQEHLYIEPQGMIARVEd--GVLTVEGSLQCPYYVHAALVY 222 
WP_066747123 156 -RG-------D-----LRKGFAeA---D-VVVEGEWETGLQEQMYLETQGMAAWRAg--DGIELLGSLQCPFYVVNAVAA 216 
WP_050434681 159 -KGcaelperDaseaaIDAVIEaC---D-VVVSGHYDTHHQEQLYIEPQGFVTWWDd--DGVHVTGSLQCPYYIHKVLKR 231 
WP_006928879 150 -RG-------H-----LQEARQaA---F-RAIELETQTGFQEHMYLEPQGMVAIPQe--EKIIIKGSLQCPYYIKNALGE 210 
WP_011640549 151 -KG-------N-----IAEAIKnS---K-FFIEDEFRTGYQEQAYLETQSMIGVYEd--NRVTVYGSMQCPYYVKEALIQ 211 
WP_124692218 307 MVadsGFPLEHLFVHP-CYTVGYGSKDHC--NVPFYGLVAAlYGD-GHPVRFAVDRFEHFQTSLKRHAFDMQYTMAVdRK 382 
WP_014784746 225 AF---DLPADKCRVIQtETGGAFGGKEDFpsVIGTHAALLA-KKA-GRPVKIVYDRGEDMAATTKRHPSRTRHRTAV-SK 298 
WP_011218648 208 VL---G--HDHVRAIQcPTGGGFGGKEDYpdVLAGPLAVAV-EKL-QQPIRIVLERSEDIAFTSKRHPVAFHYRTGI-DK 279 
WP_013386593 210 CM---GFDPENVRIVQtTTGGAFGGKEDYpsLIAGHVAVAA-YKA-KQPVQLIFSREEDVEVTPKRHPSIIHLTSYI-DQ 283 
WP_014488376 217 VL---GVEDSKVRVISpTIGGGFGGKEHYpdILSAAVAVAV-HKL-KKTVKLILDRQFDLAYSVKRQPAQITTKIAL-DE 290 
WP_110138662 223 AT---GLPEEQVRVLQcATGGAFGGKEEYpsHIACHAALLT-LKAgGRPVALIYGRGEDMAVTPKRHPSRSRVRLGA-SR 297 
WP_066747123 217 AL---GLPHEKVTVRQsATGGAFGGKEDYpsILGVYAALLA-WKS-GKKVKIVYDRSEDLLVSPKRHPSKSRYRMGL-TK 290 
WP_050434681 232 AL---DLASERVHVTQaVTGGGFGGKEEYpsIIALHAALLA-KKS-GRPVRMIYDRTEDIEATTKRHPATIEITSGC-DR 305 
WP_006928879 211 IFk--G--LREITVVQsTTGGAFGGKEDFpsLLAAHAALLA-YKS-GHPVAIFYDRAEDVLVTTKRHPSFSRNRVFV-DR 283 
WP_011640549 212 AL---GWPEDGIRVIQlPTGGGFGGKEDYpsIIGVHAGLAA-IKA-QKPVQLVLDRQEDISCSTKRHPAIIKIRSYI-DD 285 
WP_124692218 383 TGKLQSFQGTFTGNGGGRSNFSPsvvmVAATAAQSVYYFPKNDLIAVAEATRAIDAGSARGYGTLQSMAATEMMIDEMAE 462 
WP_014784746 299 DGRLLGCEIDFAIDGGAYMTLSPvvlsRGTIHAAGCYHWPAVRVRAKAMATNVPPHGAFRGFGAPQSLFALERHMDKIAK 378 
WP_011218648 280 HGNIVAMDVTFDVNSGAYLSLSGivlqRSITTVTNVYDIPNVRVEGHAWATNTVPTGAFRGFGSPQTCFCIETHLNHVAK 359 
WP_013386593 284 NHKIMGMEADIKLEGGAYLTLSAivlqRSMFAAIGVYNVENVFVRGQAIATNTVPSGAFRGFGAPQSIFALETHMEKCAK 363 
WP_014488376 291 NNNIIALDVVSDMDAGAYESSSRvimqRCTYTAANVYHFPNVRVLGRLYCTNNVPSCAFRGFGGPQAIFAIERTMDNVAN 370 
WP_110138662 298 DGRLRFIDIDFAIDGGAYLTLSPvvlsRGVIHAAGPYRCDNIRVRGRAVATSHPPFGAFRGFGAPQSIFALEAALDGLAR 377 
WP_066747123 291 DGKITALDAEIKLDAGAYTTLTRvvlqRTHLHAAGCYYVPNVRVRSSAWATNTPPNGAFRGFGAPQAIFAIERTMDLAAE 370 
WP_050434681 306 DGTLRALKARIRMDGGAYMTLTPvvlsRGTLHAAGAYRWRDVWIDSVAVATNTPPNGAFRGFGAPQTIWAIERHMDRIAR 385 
WP_006928879 284 NGKILGLDIEFYLDSGAYCTLSPvvlaRAALTVTGCYFIPHVRIVAKAVATNTVPSGAFRGFGGPQAIFTMEMIVEEIAR 363 
WP_011640549 286 QDQITAQEIDIKTDAGAYAGLSSvvlqRLMYSASGVYNIKNLKVQARAYATNQVVSGAFRGFGGPQAFFAIEMHMENIAQ 365 
WP_124692218 463 ELGIDPIEFRVRNALLSGMKNtqGAIAgGALRADEVLERARRHPLWTERAQRKRDYe------aAHpN---------ERY 527 
WP_014784746 379 VVGITPEELRRRNFLHTGDQTatCQVVkDPIDLDAMLTKTLTAADFHAKQARFATEn-------KT-Sp--------IKR 442 
WP_011218648 360 QLGQDPAAFKQRHFLQSDSTTltGAKIfGDLVLDQMMARITDLSDYSQKTRSYLDQa-------pNtA---------TRK 423 
WP_013386593 364 EMGVDALDFKLKNLMKQNDRSstNGIMrDPIILPEMVERTDELSKFRKKKAEFSKYn------kTN-Pe--------KLK 428 
WP_014488376 371 KINVDPIELKRKYFVKQNDPTitGGIFhDNIILPKMLDLALKESDYENKVKKY------------K-Dd--------MYK 429 
WP_110138662 378 DLGMAPDVLRRRNILAPGDISpaGQSIeGPLDMRRVIDQALEVCGYHAKVEAYRRWn------vQG-Ga--------TRK 442 
WP_066747123 371 RLEMDPLDIRLLNTIKTGDLFpyGQVLrEGNNAEGVLLKAAELSDYRRRREILSQQ--------SE-Gr--------FRK 433 
WP_050434681 386 ALGVDPVALRAQNLLHSGDTTatGQTLgLSVGGAACLEAALAESGYKEKRAAGp---------vRQ-Gr--------TAR 447 
WP_006928879 364 QLNLAPHTVRAVNLIDVGQTTatEQVLrYSVSNKQTFNDVLERSGYQRKYAQFKEHnapilqrlRD-GkfpksrpddVLK 442 
WP_011640549 366 QLNQDSLELKRKYFFQQGDTSstSGLFqYPIKLDEIATEIAKMSSYRRKRQLYSSQ--------KE-----------RLR 426 
WP_124692218 528 GVGFGCVQKDFgtg------geaAFVRVALTPEG-RIVLHHTGVEIGTGMSTSQAVMCAEWFGRPADEVRTAVTDwsdlp 600 
WP_014784746 443 GMGFASFFHGAgftgsg-errlnSLVKLEVDHEG-RVVLLVSSTEFGQGTNTILCQVAAQSLNIPYEQVLIAQPD----- 515 
WP_011218648 424 GIGMAIFQHGCgfagdledtlvrAKIRLIKEPDG-NVYILASNTDIGQGLSLTFCKIVADSLCKPLESVHLAIPD----- 497 
WP_013386593 429 GIGMSIFFHGGgftgsgeqdhikAKIKLHKSSEG-KINLLLANVEMGQGVHTTMKKIAAKTLDLPIESIAYNNPD----- 502 
WP_014488376 430 GIGISCFLHGCaftgs--gerdiIKAKLKLKKKGnKVTILTSNTEIGQGLHTTFRKIAAYNLNIPLENIDISVYD----- 502 
WP_110138662 443 GIGLATFYHGAgftgng-elalrSRAGLRVGATG-LVEILTSTTEMGQGMQTTLSRIVAEALSIPYEGVAVARPD----- 515 
WP_066747123 434 GIGISLALHGGgftgag-eanmgTTAKMTF--DGkRFRIYTSSTEMGQGASTVLPMVAAEALGVELEDVLYVEPD----- 505 
WP_050434681 448 GIGAAVFMHGAgftgsg-ermlkGKVAIDLLPGG-KLQIRTGSTDIGQGTETVFRQIAADAAGIALDHVDFAVPS----- 520 
WP_006928879 443 GIGLSVFLHGAgftggg-enrikGKIRIEIDEDG-HPVIYSAQTEMGQGQQTAFRKILADVLNIDREQVLLAPVN----- 515 
WP_011640549 427 GIGCSVFSHGCgftgdneeklikPKVRLKKYSYN-CVQIFVSSTEIGQGALTTLRKIVAQALEIPIEWVKHEYPD----- 500 
WP_124692218 601 mvGNVdTYtvkqeeqdrlaadpmwtpvhASPSSASNSVYFFGHATKETARVVFEHglwpaamaiwTrgigggqA-APlvv 679 
WP_014784746 516 --THRvPN--------------------SGPTVASRTAMIVGKLVENACANLLATlrtap-nnlrEh-------yTP--- 562 
WP_011218648 498 --TGVvPD--------------------SGPTVASRSIVIVGYLLEKAAEKLKSCwv----------------------- 532 
WP_013386593 503 --TDYtMD--------------------SGPTAASRTIMVVGKLVQEACEELKANwidd--------------------- 539 
WP_014488376 503 --TNLiPN--------------------TGPTVASRSVMIVGYLIQEACKKLKDRwnes--------------------- 539 
WP_110138662 516 --TRDvPN--------------------SGPTVASRTCMVVGGILTQAARDLIARlrad--amlpS-------AyNY--- 561 
WP_066747123 506 --TKYtPN--------------------TGPTVASRTTMYAGKAVQDACENLKKAieng------------gaplS---- 547 
WP_050434681 521 --TTVvPD--------------------SGPTVASRTVMVVGSIVESASREVAARvtae--qaaaG-------------- 562 
WP_006928879 516 --TDLvPN--------------------SGPTVASRTTMVVGSLIADIGQQIIERlsnel-qkeyD-------I--Pfey 563 
WP_011640549 501 --TDFcPN--------------------SGPTVASRTIMIIGKLLYDCALEMKDRwne---------------------- 536 
WP_124692218 680 rrE-DarwterGltangleplplerlvktayeanfvtaavghtfnrwqwaeadfdvggqkvrrplDg--lAVrygdgsrs 756 
WP_014784746 563 --Q-Efc---aAalhhrn------------------------------------------ehgtlE----AE-------- 582 
WP_011218648 533 egEhQ------------------------------------------------------------E----LE-------- 540 
WP_013386593 540 --------------------------------------------------------------keqT----II-------- 545 
WP_014488376 540 --------------------------------------------------------------eeiE----IT-------- 545 
WP_110138662 562 --D-Efr---aAcarlha------------------------------------------sggvtT----VI-------- 581 
WP_066747123 548 -----------Gkalvea------------------------------------------akrylEkegrAEa------- 567 
WP_050434681 563 -----------Gtfaeagdr-------------------------------------llargeavG----CL-------- 582 
WP_006928879 564 ---------rtGyfyggqhilsf--------------------------------skvakkfaglR----FE-------- 590 
WP_011640549 537 --------------------------------------------------------------eefD----IT-------- 542 
WP_124692218 757 pQPYdvirrSnvfyPPaqrn-------nagVTYYSANAALAELAVNPTSGKVRLLSHHSVLECGKPVVEELVSGQLQGGI 829 
WP_014784746 583 -ARY-----Qs---PGdifwddd-kykgeaYPAFGWAIYVAEVAVDTRTYQATCTNFWAMQEVGKVLHPVLAAGQIEGGV 652 
WP_011218648 541 -EVY-----Rk---PDyhvwdqn-tyqgnaYQVTSYGVNVVEVDVDMATGETQITGAWAVYDIGRAIDAQVFKGQIDGGL 610 
WP_013386593 546 -TNY-----Rq---PKgfnwddk-nfigdvYNSYSWGVNVVEVSVDPITFQVDVDHIWAIYDIGKAIDEMVVRGQIEGGI 615 
WP_014488376 546 -EDY-----Kh---PShlvdwdstnlrgdaYPTYGLGINVVEVEIDKFTLEVKIVGVWAVFDCGYAIDEKIVEGQIKGGV 616 
WP_110138662 582 -ADY-----Rh---PAgsewdes-tfqgspYASFAWACYVAEVEIEVVTGEARILDFTAVQEVGRVVHPTVAAGQIEGGV 651 
WP_066747123 568 -LGY-----Ni--fTDgqswdee-kfagdaYHGYAWIANAVEVELDMDTYEATPLSAAVAAEVGRAINPMQAKAQLTGGV 638 
WP_050434681 583 -KQY-----Ep---PAfvqwddt-tykgdaYPCFAWACDIAEVEVDLDTFEVSVTNFWSATDVGKAIHPVMCKGQIEGGT 652 
WP_006928879 591 -KEY-----Kh---PPfikfsee-nwkgdaYPVYSWAAAVAETEVDPITFNIKVTRYYTTHEIGKAINYDQSIAQIQGGS 660 
WP_011640549 543 -HEY-----Vy---PKnlkwdne-kfqgnaYPEYSWGANVVEVEIDPITYTLNILGIWAVYDIGTPIDEKIVKGQIEGGI 612 
WP_124692218 830 AMGIGHALHEYLPLY-EDgPGNGTWNFDRYHLPRAHDVAvwSQTGDIL--P-PiSDT-DPPKGIAEVVMIPIVAAIVNGI 904 
WP_014784746 653 AQGIGYAIYEKCEWR--D-GALKNNQMTNYIMPTSADLP--NIHVLFEeiPsI-HGA-FGAKGIGELPMDGPAPAILNAI 725 
WP_011218648 611 VQALGYGSCEKMELT-SD-GVFAQKTMADYVIPTALDVP--SIESDLVdnPyP-YGP-NGAKGGGELTHNGGAAAFAAAV 684 
WP_013386593 616 IQGLGYGGLEVMEV--KK-GKIQQKSITDYIISTSKDVP--KITSELMnvPyI-HGP-YGAKGLGELTLIGTAPAYSLAV 688 
WP_014488376 617 AQALGWGALENIVNK--D-GRFLQVKMSDYMIPTSLDLP--EIKTYIMgePyQ-YGP-SGAKGIGEITFDGAASAYASAM 689 
WP_110138662 652 VQGIGYALFEDVHFG-AD-GQMANNRVTNYIIPTSADIP--PIRVLFQesRhG-AGP-GGAAGIGELPMDGPAPAIINAI 725 
WP_066747123 639 LQAFGWAHIEDLKTD-AK-GRYTAAHMNAYLVPTTLDTP--EWKVELLedPcP-AGC-YGAKGLGELPCDAGAAAFVAAI 712 
WP_050434681 653 LQAIGWALCEEVVWK--D-GLIKNPRMTNYIIPTSLDAP--PFHTLLVeePwP-YGPgGGAKGIGELPMDGGAPALAAAI 726 
WP_006928879 661 LQGIAYAVFEKMERH--N-GRLDVRGFSDYIIPTTVDMP--LMDIKILenPyP-FGP-FGAKGLGEMPLVGAAPAVVSSL 733 
WP_011640549 613 VQGLGFGCMEVL--NsKN-GQLLQSSLTDYLIPTAVDFP--EIESKLIhnPyE-NGP-FGARGLGELSLVGAAPALALAI 685 
WP_124692218 905 AHAIGHRFTDLPVTPEKI--RE 924 
WP_014784746 726 EDALGIAFNQCPLLPEDV--FE 745 
WP_011218648 685 ELAIGKPFSSIPVTPEKV--CE 704 
WP_013386593 689 SNALDMEINKIPIKPEEL--IK 708 
WP_014488376 690 ENALKHHFTKIPILPENI--AE 709 
WP_110138662 726 NAALGTEIRHVPAMPEHI--LA 745 
WP_066747123 713 DHAAQIFSHCAPMTGERI--FE 732 
WP_050434681 727 EHAVGLIADSLPMTPERLhrIA 748 
WP_006928879 734 RMIFGRPINKIPVMPEDL--FA 753 
WP_011640549 686 QNAIGQKVTQIPVTPEYI--ME 705 
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