Conserved Protein Domain Family
PvdQ

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COG2366: PvdQ 
Acyl-homoserine lactone (AHL) acylase PvdQ [Secondary metabolites biosynthesis, transport and catabolism]
Statistics
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PSSM-Id: 441933
Aligned: 386 rows
Threshold Bit Score: 338.425
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_083458015   11 TDLVYSrrmrrVAL-CVSLfasFVVgcScdddpPatdagsdagpqtilhsvPETERFTIPCLSEEAQIVRTELNVPHIYA 89  
WP_011413253    2 lrIGGGv----LAL-VLVV---LVGlmTw---ePf---------------fARETAAPSTHRTYRAEILRSDYGVPHIYG 55  
WP_011542672    3 rrIFPGf----LLL-LLVV---AASlaLw---ePl---------------tAE-APQAPAFKPADVRIARDKFGVPHIFG 55  
WP_014785976    1 ----mplrrriLSLaTLTL---AIGtaV-----Ps---------------iAQAk-ASTYKPMKGSEILWDKWGVPHIFA 52  
WP_014785976    1 ----mplrrriLSLaTLTL---AIGtaV-----Ps---------------iAQAk-ASTYKPMKGSEILWDKWGVPHIFA 52  
WP_047857530    5 rrILFGl----GVL-ILAA---ALGltTw---ePl---------------lAA-RAAPPPAHPYDVTITRDNFGVPHIFG 57  
WP_010238987    6 GGLGLAv----LAI-VLIA---VIGlmTw---ePf---------------fAREGHAPDSDRTYTAQIVRDEFGVPHVYG 59  
WP_068350894    5 krGSFAl----LAV-AVLG---VAGlaTw---ePf---------------mAE-AAAPQSQRTYSAEIIRDEWGVPRITG 57  
WP_069050209    6 krIALGl----VAL-IVVV---AIAlaVw---ePl---------------vAE-EGKAPPVRSYDVEIVRDDFGVPHIFG 58  
WP_089134967    1 ----MGl----LAL-IVLL---AIGlaVw---ePm---------------sVA-ESAPPPEGSYEARIVRDEFGVPHIFG 49  
WP_083458015   90 ASREDAFCALGFVMARDRFFQMDLTRRLSQGRLSELLG----DAALATDIEERMKGGAFVTGMQTDALTDDEAREVDAFA 165 
WP_011413253   56 ETDADVAYGVAIAQSEDDFFTLQDVVAMSKGRYGAIAG----PDGAQVDYVYYLLDARGTAERQYGSLPADTRAIFDAYA 131 
WP_011542672   56 KTDADVAYGVAYAHAEDDFSTLQEVLAMTRGRAGAMLG----PEGAKVDYAEALLGVRATAKRDWPRLPADVRALFTAYA 131 
WP_014785976   53 KNTKDMFYLYGYAQTEAHGELLMHVMAGSRGRSSEIYGaganDRNLKTDRWVWLNEVPKRSALWLSQQIPEFRSYLDSFA 132 
WP_014785976   53 KNTKDMFYLYGYAQTEAHGELLMHVMAGSRGRSSEIYGaganDRNLKTDRWVWLNEVPKRSALWLSQQIPEFRSYLDSFA 132 
WP_047857530   58 KTDPDVAYGIAYAHAEDDFSTLQEVVAMTRGRLGALIG----QDGAKTDFVVHLLGARATVARDYMQQPADVRALLDGYA 133 
WP_010238987   60 TTDADVAYGVAIAHAEDDFTTLQDVVAMSRGRYGAIAG----QDGAAIDYAYHLTGARETAEREWPKLPADTRALLDAYA 135 
WP_068350894   58 KTDADTAYGVAIAHAEDDFFTLQDVVAMSRGRYGAIAG----EEGAKIDFAYHLIDARGTAEREYPRLPADTRALFEAYA 133 
WP_069050209   59 KTDPDVAYGVAFAHAEDDFATLQEVAAMTRMRSGAMTG----ADGAKVDFAAHLLDIRGTVDRKYAQLPADIRALLDAYA 134 
WP_089134967   50 KTDADVAYGVAYAHSEDDFSTLQEVTAMTRGRMATLNG----SESAPIDYIAALLDVRGTVNRKYDQLPADVRAVLDGYA 125 
WP_083458015  166 AGINAYVAAasNgdlpLpsEvRlgaallgagtrpwSLLheWDRRDVIAC-GVTVLystsfetgdvgrdrDHaqVdtlfEg 244 
WP_011413253  132 TGLNQYAEE--N-------P-Delk-------lagLFP--VNGEDVAAGfALRQPf-----------------Ff---Gl 172 
WP_011542672  132 AGLNHYAEK--H-------P-Devr-------lsaLFP--VTGEDVVAGfVLRSPf-----------------Ff---Gl 172 
WP_014785976  133 AGINAYAAA-------H--P-Dklsa-----eakqVLP--ITPLDVIEH-TQHF---------------VN--Fe----- 172 
WP_014785976  133 AGINAYAAA-------H--P-Dklsa-----eakqVLP--ITPLDVIEH-TQHF---------------VN--Fe----- 172 
WP_047857530  134 SGLNRYAET--H-------P-Gevr-------larLFP--VNGEDIATGfVVRSPf-----------------Ff---Gl 174 
WP_010238987  136 VGLNDYARD--H-------P-Geik-------lgkLFP--VNGIDIAAGfALRQPf-----------------Ff---Gl 176 
WP_068350894  134 AGLNQYASE--H-------P-Gevk-------lanLFP--VNGMDVAAGfALRQPf-----------------Ff---Gl 174 
WP_069050209  135 AGLNHYADK--H-------P-Devr-------ltgLFP--LNGQDIAAGfALRSPf-----------------Ff---Gl 175 
WP_089134967  126 SGLNAYAAE--H-------P-Devk-------lakLFP--VNGQDIAAGfVLRSPf-----------------Ff---Gl 166 
WP_083458015  245 MPdralrlagvRQD--VMErYAPprdtssaSGWgletasesARVTR--Rr-gRGrhh-asvETAVmdrltehlerIVA-- 316 
WP_011413253  173 AGv--------IGQ--LSD-NKPp------RREfg----pdIPGFPreGsggDEiev-erkPAQT----------A---- 216 
WP_011542672  173 DSv--------LGS--LVE-GTPi------GREgg----paLDATG------KLv-------------------pR---- 202 
WP_014785976  173 ----------fVAGraLME---Prn-----------------------------------aTRTA----------AASte 194 
WP_014785976  173 ----------fVAGraLME---Prn-----------------------------------aTRTA----------AASte 194 
WP_047857530  175 EGv--------LGA--LTG-DKPl------PIEsa----gaRPGAP---------------------------------- 199 
WP_010238987  177 DRy--------LGP--LVE-GKPl------PPEyg----psLSGTStiDdapRImddaapePRKT----------A---- 221 
WP_068350894  175 DAv--------IGP--LVA-GEDl------RREhg----pdIPGFPraPlpgAQepa-apaPQQ-----------A---- 217 
WP_069050209  176 DSv--------LGA--LVE-GNDl------PIEgg----pqLTGKEv--------------------------------- 201 
WP_089134967  167 NNp--------IEA--LVQ-NKPl------PREgg----prLSGEPvkSsihPLs-----pDKLI----------N---- 206 
WP_083458015  317 ----R-Mprt------pgeGYGSNVWAVAGSSTPDGRALLAGDGHLQLSVPALFWQVGIDTAFlsegaddTRLLGATIPG 385 
WP_011413253  217 ----RaMplpwg---emaaLSGSNAFAVAPEKSGEG-TILISNSHQPLEGGVAWYEMVVESGEg------WHFTGANFPG 282 
WP_011542672  203 ------Altpvg---rdpaDNGSNAMAVAPARSTDGATRLVSNSHQPWTGGVAWYELVVHSEEg------WDFAGATFPG 267 
WP_014785976  195 taslE-MpespfaptnmdmQDGSNGWAIAPSHSTSGNAMLLMNPHLAMAGEQTYFEAQLVAPG-------INLFGASQVG 266 
WP_014785976  195 taslE-MpespfaptnmdmQDGSNGWAIAPSHSTSGNAMLLMNPHLAMAGEQTYFEAQLVAPG-------INLFGASQVG 266 
WP_047857530  200 ------Aitplg---pepgQSGSNAFVVAPSRSADGFTRLVSNSHQPWRGGAAWYELVVHSQAg------WDFAGALLPG 264 
WP_010238987  222 ----DaGpipmg---edaeYAGSNAFAVAPEKS-GGPTILVSNSHQPWRGGVAWYELIVQSDEg------WHYAGANFPG 287 
WP_068350894  218 ----RtLvlplg---edaeHLGSNAFAIAP-RKGGGITTLVSNSHQPLRGGVAWYELVVESGEg------WHFAGANFPG 283 
WP_069050209  202 -----aRvtpig---pepdMNGSNAFAVAPARSTDNVTRLISNSHQPWRGGVAWYELVVHSEEg------WDFAGATFPG 267 
WP_089134967  207 ----DqTatpvg---pdpdENGSNAYALAPELSPEGKTRLISNSHQPLRGNVAWYELVVHSEEg------WDFAGANFPG 273 
WP_083458015  386 LPTIGVGTNGRVAWSQTAYFADVTDWYREEIVLGddgsprGSRFQGEERALVRVDEEYVIAdvpaldsegrtesiarftt 465 
WP_011413253  283 SPFPFLGHNRTLGWTNTVNRPDMVDIYELVLN-Edg---tQYRLDGEWRDLEAREVTLPVK------------------- 339 
WP_011542672  268 SPYPFLGHNKYLGWTNTVNRPDLIDVYRLVLD-Asg---eKYRFDGGWRPLEEKRIWLKVK------------------- 324 
WP_014785976  267 LPVMRFCFSDYLAITNTVNTNNGALQFDIKEQAG------GYLYDGKVLQYETSQYPFRVK------------------- 321 
WP_014785976  267 LPVMRFCFSDYLAITNTVNTNNGALQFDIKEQAG------GYLYDGKVLQYETSQYPFRVK------------------- 321 
WP_047857530  265 APYPLMGHNKTLGWTNTVNRPDLIDVYQLVTDg------eRYRYDGQWRRLEKQRVWLPVK------------------- 319 
WP_010238987  288 SPFPFLGHNETLGWTNTVNTPDMIDIYKLVLD-Dsg---tRYRLDGKWRDLEATDITLPVR------------------- 344 
WP_068350894  284 SPFPFLGHNEHLGWTNTVNTPDMIDVYQLELD-Dsg---tRYRLDGQWRDLESRMVTLPVK------------------- 340 
WP_069050209  268 SPYPFLGHNKTLGWTNTVNRPDLIDVYKLELS-Ddk---tQYKLDGKWRDLEARQVWLKVK------------------- 324 
WP_089134967  274 SPFPFLGHNKYLGWTNTVNRPDLVDIYKLTLN-Ddk---dAYRFDGEWKPLEKKRVWLKIK------------------- 330 
WP_083458015  466 fdgrwitsiEg-D----AVEdgaerpaSAVNM--MGEwIVPgdvdgdgVVSAISFDYGPFDGgvL-LRAFRLFGLAENVE 537 
WP_011413253  340 ---------Lg-Plv-lPIR-------ETVYRsvHGP-VIVn-----dNGA-FAMRYGGIDNi-DqLDAYYRLNKASTLE 393 
WP_011542672  325 ---------Vg-Pfv-lPVP-------RTIYRsvHGP-VVKn-----dKGA-FAIRYAGQDQa-KmVTQYYRLNKARDFA 378 
WP_014785976  322 ---------Qk-DgsftTEV-------VQVQKtvHGP-IIRr-----dKGVPVALLTAGLDKp-FfLEQYWKMDTAHNFA 377 
WP_014785976  322 ---------Qk-DgsftTEV-------VQVQKtvHGP-IIRr-----dKGVPVALLTAGLDKp-FfLEQYWKMDTAHNFA 377 
WP_047857530  320 ---------LwgPlv-lPVP-------RTVHRaeQGP-VLTn-----rSGS-YAIRYGGADQl-KmVEEYYRLNRATDFT 374 
WP_010238987  345 ---------Vg-Pft-lPIR-------RTVYRsvHGP-VVKn-----dNGA-FAIRYGGIGSi-GqLDAYYRLNKAKTYD 398 
WP_068350894  341 ---------Lg-Pvv-lPIR-------REILRsvHGP-VIRn-----aKGA-FAIRYGGIGQl-QqLDAYYRLNKAKTFA 394 
WP_069050209  325 ---------Vg-Pft-lPYP-------QTVYRsaHGP-VILn-----aKGA-FAIRYAGIDDl-KmLEQYFRINKARNFD 378 
WP_089134967  331 ---------Fg-Pfv-iPYP-------QVAYRsiHGP-VIIn-----dSGA-YALRYAGIDQl-DmLTQYYRINKASNFD 384 
WP_083458015  538 DYRQAMRHFIGYGGSMMASDTTGDVLYSAYHAVPCRSylprdgatnrwiAGa--DprRLIDG-TQYGGWSipltadgrvd 614 
WP_011413253  394 EWQAILSRMDVPSTNFIYGDAEGNIAMVYNAAIPDRP------------EGh--DwrGILPGdRSDLIWD---------- 449 
WP_011542672  379 QWRAAMAGQGVPATNFVYADAKGNIGLFYNAMFPDRP------------AGf--DwrGVLPGdTSAALWT---------- 434 
WP_014785976  378 EYQAQLRRLEVPMYNILYADRDGHIEYLFNANVPRRT-------------GdwaTwtKPVDGsTSATMPH---------- 434 
WP_014785976  378 EYQAQLRRLEVPMYNILYADRDGHIEYLFNANVPRRT-------------GdwaTwtKPVDGsTSATMPH---------- 434 
WP_047857530  375 QWQAALAMQGIPGTNFFYGDAAGNIAFFYNASFPNRK------------PGf--DysKVLPGdTSDAYAP---------- 430 
WP_010238987  399 EWYGILSRGQIPSTNFIYGDAEGNIAYVYNAAIPERQ------------AGp--DwrTVLPGdDSALIWQ---------- 454 
WP_068350894  395 EWEGQLSRLAIPSTNFIYADKTGTIAYVYNAAIPARP------------EGikaDwrSILPGnRSDLIWQ---------- 452 
WP_069050209  379 EWKAAMAIQGVPATNFIYADAAGNIAMAYNALFPARK------------PGa--DwrGVLPGnRSELIWQ---------- 434 
WP_089134967  385 EWQAAMAGQGVPATNFIYADADGNIGMYYNAMFPDRP------------EGh--DwrTVLPGdTSATLWQ---------- 440 
WP_083458015  615 etaaatdadgCAVPFDEWPQALSPARGYVQHANNDPGAI-----------ATdgdlfddpHYIGGPWIEGYRAARIAQRL 683 
WP_011413253  450 ----------GPVDYAAIPKYVNPASGWLMNANNTPFRAagpdsdlspdsVS--------PYLGVElKQTNRSRRAWKLM 511 
WP_011542672  435 ----------RTLPFDRVPALVNPRSGYVMNANNTPWVAagpgdeldaaaFS--------PLLGIEdDMTNRAVRLIELF 496 
WP_014785976  435 ----------GILSYDELPKQIDPASGYVQNSNEPPWDAawpnm-mdrsaYP--------AYISS-FFPlFRSDRALRML 494 
WP_014785976  435 ----------GILSYDELPKQIDPASGYVQNSNEPPWDAawpnm-mdrsaYP--------AYISS-FFPlFRSDRALRML 494 
WP_047857530  431 ----------GTVAWSLVPRNVNPASGFLVNGNNSPYQAagpgs--eippqP--------PLLGVEtDTTNRGDRALELM 490 
WP_010238987  455 ----------DTVDYASLPQYLNPASGWLMNANNTPFLAagegsdlspdsVS--------PLMGVElKMTNRGLRAWKLM 516 
WP_068350894  453 ----------GSVDYTALPRVVNPASGWLYNSNNTPFTAagagsdlvpaaFS--------PTLGIElKQTNRSRRAYKLL 514 
WP_069050209  435 ----------GHLPWGKVPLLVNPASGYIMNANNTPYVAagpgdelepeaFS--------PLMGIEsDMTNRARQAIKLF 496 
WP_089134967  441 ----------GALPFTRVPALVNPASGYVMNANNTPYIAagpgdelkrnnFS--------PLLGVEdDQTNRSRRSIALL 502 
WP_083458015  684 eeaiA----AERATIAEMQDIQGDHHSNLGEEWVPLFLDELERArtlaAGTPAegtsdariaAmwraeqaafedVEGRLR 759 
WP_011413253  512 ----Se---AGRLDNDTLRRIKYDTAYEREGYVADLWDALEQFEp--gDADLG---------E-----------ARRILL 562 
WP_011542672  497 ----Ea---SGPIDGARLKAIKYDTAYARTGYAKAWIDRLLALDtk-dDRALA---------Q-----------AQALLR 548 
WP_014785976  495 ----Se---DKKISFDMLLEKKFSTRMEMADRVLDELLADVDQYg---SPRAK---------E-----------AAAVLR 544 
WP_014785976  495 ----Se---DKKISFDMLLEKKFSTRMEMADRVLDELLADVDQYg---SPRAK---------E-----------AAAVLR 544 
WP_047857530  491 ----Sa---LPFISEGDLKRIKFDTGVAKGGYLEAWFKELLAVDph-gDKRVA---------Q-----------ARELLS 542 
WP_010238987  517 ----Se---ADRLDSDTLMRIKYDTAYENAGYIKRMMDDVRAIDpk-qHPDLA---------E-----------ARRLML 568 
WP_068350894  515 ----Se---AGVIDRAALEAIKYDTAYAREGYVARLFDALEGLKa---EGQTT---------K-----------ARDLLL 564 
WP_069050209  497 ----Ea---AGQIDAATLERIKYDVGYDKSDYATGWIAALLAVEpe-gDERIT---------Q-----------AQALLR 548 
WP_089134967  503 ----EranaDGKISDAELWAIKYDTGYEKAGYAKDWLDRIASLDlk-dSAKLL---------K-----------AQQLLA 557 
WP_083458015  760 AWrdaDYPTpsgvatfysepaaedRAHAIATTIFGTWfprFVRGTLDDeG-IP-------GGlspavtgdtyrmqtmlll 831 
WP_011413253  563 EW---DFTA---------------DNVGPGDALALLMirdFMSAEYQN-------------------------------- 592 
WP_011542672  549 KW---DWTL---------------DGRGKGDALALMVlrpANGRHYQR-------------------------------- 578 
WP_014785976  545 TW---DRQC---------------EANSRGALLFYTWaqkFISTSVGMtTvAAqknwaipYDy----------------- 589 
WP_014785976  545 TW---DRQC---------------EANSRGALLFYTWaqkFISTSVGMtTvAAqknwaipYDy----------------- 589 
WP_047857530  543 QW---DWNW---------------DGKGPADALAFSLlrlPHRFHYER-------------------------------- 572 
WP_010238987  569 EW---DLTA---------------DNIGRADAIALLMvreFMASSYQK-------------------------------- 598 
WP_068350894  565 SW---DFTA---------------DGKGAADAIAMLMlrdFMAADYNN-------------------------------- 594 
WP_069050209  549 AW---DWQM---------------DGKGKGDALALMLmrpAMRQSYRR-------------------------------- 578 
WP_089134967  558 QW---DWNL---------------DGKGPADALALMVlrpANKSHYNR-------------------------------- 587 
WP_083458015  832 vRgrgpgNpeslgsyepareesvffddVaTTe-iETSHEIVVRALRDALVFLRSEPsapgeggfgSD-D-PddwiWGLRH 908 
WP_011413253  593 -------Ka-------------------eAP--------DVATHLRKAVDHLQEHF---------GRlDpP----MSELL 625 
WP_011542672  579 -------Ra--------------------PP--------DPQEVLRDVVAHLQEHF---------GGlDpR----LGTVL 610 
WP_014785976  590 -N-----Qp------------------LtTPrgiKDPKL-AVQMLADAADETVKLY---------GAlDrP----WGDVM 631 
WP_014785976  590 -N-----Qp------------------LtTPrgiKDPKL-AVQMLADAADETVKLY---------GAlDrP----WGDVM 631 
WP_047857530  573 -------Kp--------------------KP--------DPLGVMAEAAGYLRKHF---------GKlDvP----LGELI 604 
WP_010238987  599 -------Sp--------------------WP--------DAAEELRRSKDHLQKYF---------GSlTpP----MSELL 630 
WP_068350894  595 -------Kp--------------------FP--------DVAQKLNAAADHLMTHF---------GRlDpP----QGDLV 626 
WP_069050209  579 -------Lp--------------------LP--------DAREELTAAIEHLTKHF---------QSlDpR----LGTVL 610 
WP_089134967  588 -------Gt--------------------MP--------DPRQILEDTVDHLSQYF---------GQiDpP----MLDVL 619 
WP_083458015  909 GVrfESllADFlgddpmfsifvdnfsitperielAegigegdpraGltfFPRPGDQ---FDVDA-ANpGls--gERFTHG 982 
WP_011413253  626 RL--RQ--DPGlh--------------------aV----------D---LPLDGGS---DTLRAsTTwQvd-pdGRLRLV 664 
WP_011542672  611 RL--RH--GEGpn--------------------rI----------D---LPLDGGN---DTVRAsTLwDee-pdGRLKVR 649 
WP_014785976  632 KI--EI--NGQsdgdikav--------rgpalngV----------S---LPGNGGYgnlGVFRV-FTwGpll-egKKTPI 684 
WP_014785976  632 KI--EI--NGQsdgdikav--------rgpalngV----------S---LPGNGGYgnlGVFRV-FTwGpll-egKKTPI 684 
WP_047857530  605 RL--RQ--GK------------------------V----------D---LPLDGGP---DSLRAaTTyDea-pdGRLAIR 639 
WP_010238987  631 RL--RQ--GD------------------------V----------D---LPLDGGS---DTLRAsTTwNvd-ddGRLSVK 665 
WP_068350894  627 RL--RQ--GN------------------------V----------D---LPVDGGS---DTLRAaTTwDvd-ddGRLSLK 661 
WP_069050209  611 RL--RQ--GT------------------------I----------D---LPMDGGS---DTLRAaTLwDvdekdGRFAVR 646 
WP_089134967  620 RM--RQ--GD------------------------V----------D---LPVDGGN---DTIRAsTLwDve-edGRLSVR 654 
WP_083458015  983 sGPVFRMVIALGGeqgvEGWNVIPGGQSG-ITQSEHFDDQVQLWLGNETIPMRWDVEDvVEgGigRE---VLVPM 1053
WP_011413253  665 hGDSFIQWVEWRPgervRSRSVQPFGAAItRPDSPHFTDQATLFVQKKLKPVHFWREDaLAnArsRK---IVTNQ 736 
WP_011542672  650 hGDSFIMFVTWDRggrvRSESIQPFGAATtRPDSPHYNDQAPLFVRHQLKPVLFDPAAlRAsGarFY-----RP- 718 
WP_014785976  685 hGDGFTIAVEFTKpa-vKAKSFVFYGESS-QPGSPFHTDELPLAEKKQWRDVWRTRPEiLAnLssRD---AF--- 751 
WP_014785976  685 hGDGFTIAVEFTKpa-vKAKSFVFYGESS-QPGSPFHTDELPLAEKKQWRDVWRTRPEiLAnLssRD---AF--- 751 
WP_047857530  640 hGDSFILFVTWDKagqvRSESVQPFGSAStRPDSPHYTDQARLFVRHQFKPVWFDPAElQAhAerSY-----RP- 708 
WP_010238987  666 hGDSFIQWVEWLPgqrvTSRSIQPYGAATtRPDSPHFVDQATLFIQHRLKPVHFWREDaLThAtsRK---TVSSQ 737 
WP_068350894  662 hGDSFIMWIEWAPgarvSSRSVQPFGAAStRPASPHYTDQMRLFVDHKLKPVHFWRDDlLAqAssRRkskTVTNA 736 
WP_069050209  647 hGDSFIQFVEWTAdgavSSRSIQPFGAATtRPDSPHYADQAKLFVEHKTKPVYFTRQQlMPhAkrRY-----RP- 715 
WP_089134967  655 hGDSFIMFIEWAKdgkvRSRSIQPFGAATtRPDSPHYTDQMQLFVDKKLKPVWFDPADlEKhKtsDK---VVRST 726 
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