2EUA,3GSE,3HWO,3OS6


Conserved Protein Domain Family
MenF

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COG1169: MenF 
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis
Statistics
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PSSM-Id: 440783
Aligned: 415 rows
Threshold Bit Score: 244.291
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2EUA_A        51 PQFYWqQRNGdeEAVVL-GAITRFT--------SLDQAQRFLRQ------------HPEHADLRIWGLNAFDPSQ----G 105
WP_011096030  30 WDFVYcTHST--MMRTQ-GRVLKINldsysaeaRFEAAESLINEihtki--qytseNLNpIGLIVLFGFTFSPYSar-pS 103
WP_002530655   5 DSVCFlHRNY--GMVGL-GEVTRFEt------dSPAAADVWWEAlcddlehetempDAEATGPVAFGSFTFDPDRsssrS 75 
WP_010079983  27 RAVLWaHGDD--AWRGEgGWTvlld-----gtdRLRRLSALWQAava-------grPDPTASLRGWISSTFADDSpe-pA 91 
YP_003155795  42 VSGAWlRHGQ--GVVAR-GTAWSVRsag---phRFAGAGAAFRQladrar-vddevRVRTSGLIALGSFSYADASqr-pS 113
WP_015071312  31 RSMCLvHGGQ--GVIGL-GEVARFEt------dSPDAADVWWETfsaeiedetempGVHGTGPIAFGSFAFDPDRsaspS 101
WP_065248683  39 PSTLWlHESG--GLIGI-GEAARLEatg---pdRFDALANAFRDleastd-vedlaNLRGSGLVAFASFSYSPESsr-pS 110
WP_069599704  54 AFSCWvRDTS--GLIGF-GRTLRIRarg---rdRFTELSKAWKAitdaas-iedevDLLGSGLMCFATVAYSGESev-dS 125
WP_084637251  43 SALVWlRNSE--GMIGL-GEVFSVAaqg---tdRFHELRQAWNEllsak-------assdAELFAFVAVAFSHTSah-aS 108
WP_114593465  10 AGYAFvQQQQ--GWIGN-GVTDRFEppt--ildRFTRSAEWlsd----------rlAPDG---VAFASFTFDAGSd--gS 69 
2EUA_A       106 NLLLPRLEWRRcggkatlrltlfsesslqhdaiq--------------akefiatlvsikplpglhltttREQHWPDKTG 171
WP_011096030 104 FLAIPEQMFFWsdgvawkidatichn-----------------------------lsepsrifkwpksisFKMGDFRQED 154
WP_002530655  76 VMILPKTIIGRwpgyswltqlswdsitd--------------------------dsphqqsvprppgavtVRDGVVSERS 129
WP_010079983  92 VLRIPADLRRAtpsgvrdvaqhvdadalaaa-------------------vaadrgarlladgavplpadVADRAwDDVG 152
YP_003155795 114 TLMVPRALLGVhdgeafltvvgvdeepvlpa-------------------swqelfpstpvpaecaepleI-TAGHTPDE 173
WP_015071312 102 VMIVPETVIGHraghswvtqmsydvvda--------------------------dppriqapprrapitsVAPGVIGEQR 155
WP_065248683 111 RLVIPRYLLGSvegrafvtcvnsdseesvgktl----------------tepeeilalfsagrvptvaprTMQPAHSGEA 174
WP_069599704 126 LIHVPEFVLGRrggrvwmtsiitegatp-------------------------vppvlkseplrrvtsatSSPGDLDSSS 180
WP_084637251 109 RLVVPEMVIRKkggdayltwlfdpesgiapeadhetlreralerlavlqhessvghldfpdvadvptedrLLVGHVSDEQ 188
WP_114593465  70 AIAIPEQLVRVdgpgsngrae----------------------------------------lvngvnkvrYAGASVSEVD 109
2EUA_A       172 WTQLIELATKTI-------------AEGELDKVVLARATDLH---FASPVNAAA-------MMAASRRLNLNCYHFYMAf 228
WP_011096030 155 YKHAITNVVNKL-------------LNADISKVVLARDIIAE---IHDDFDPEAhaidldeAIQRLMNT-ANGTVFV--- 214
WP_002530655 130 WRQVARLVQDIM-------------SPGELDQIVLMRDVEAK---ASSSIDPRW-------IVETLRRQFPNAYTYLVE- 185
WP_010079983 153 YAAGVRELLTRMa-----------dSGGELAKVVISRTMTVP----ADDADLWR-------AIGALRREYPQTWVFAV-- 208
YP_003155795 174 YQALVQEAIAGI-------------RAGRAEKVVLSERTTVR---TPAPLPPAV-------MLARLARAYPSTWVYHL-- 228
WP_015071312 156 WRELAGQVQEIL-------------GEADLERVLLMRDTMVR---TAQPIDPRW-------IVETLIRRQPDAWTYLVE- 211
WP_065248683 175 YRGLVKQAVQEI-------------DDGVAEKIVLSERFEIDlgtLEARCLVPA-------LAAQLNHRYPTAWTFAL-- 232
WP_069599704 181 WADLVAKVSQMLtpvgdsaevdpftEDSTLRKIVLARDELVT---SDDDIDVRS-------VLGELNRSYPSCWTFDV-- 248
WP_084637251 189 YVESIKRGVERI-------------NSGELTKLVLARDAVAE---LAQPVQVSR-------ILKELSVRYRDCWTYSM-- 243
WP_114593465 110 WMEAVATATAQI-------------REGRYDKVVLARDLQVW---ADDVLDPIG-------LAEKLAARFPSCMTFVH-- 164
2EUA_A       229 dgENAFLGSSPERLWRRRDK-ALRTEALAGTVANNP--------DDKQA-QQLGEWLMADDKNQRENMLVVEDICQRLQA 298
WP_011096030 215 --FDGLFGASPEVLLRTDGNsGFEVSILAGSMSANHpkhvihncAASPP-YKALDETYLDEKLRLEHSFALNPTLERLST 291
WP_002530655 186 ----GSVGTTSKLTVGVSKS-LITSRVLTHSPAT----------DA-NH-QTLLTALQGKGPLAAYHDEIVGRTCARLEQ 248
WP_010079983 209 ---GGLLGATPEVLATRHAG-LVGSRVLAGSMPRGA--------DEVED-AALRERLASDPRLAEEHRWAARSVLDALAP 275
YP_003155795 229 ---EDVVGASPEMLAQTEDG-RVYSRVLAGSRPVAD--------DGELD-EVDRRAFRTDAKERSEHAFAVDSVIERLEG 295
WP_015071312 212 ----GAVGVTSKLMVGDLDG-LLRTRALTHGPTG-D--------DP-TG-SQIFDALRGRGPIAAEHRRTVDWSAERIAP 275
WP_065248683 233 ---DDIVGASPEMLVRTDGP-KVFSRVLAGSRPVSG--------DDELS-AEERHAFLNDPKERAEHDFAARSVREPLMR 299
WP_069599704 249 ---AGLIGSTPELLIGVENA-RVTSRVLAGTYRVEN--------DPTSE-MPAARKLLSAHKDSTEHAFAIASLQRSLSS 315
WP_084637251 244 ---RGLIGATPEMLIQVING-TARARVLAGTLDRKS--------APVADpDYAKRALSEDEKQRHEHQLAIDSLTSQLLP 311
WP_114593465 165 ---EGFVGATPELLVRRIGN-RVESVVLAGTTT--------------PD-DAAGRALLASEKDREEHGYAKESARAALAP 225
2EUA_A       299 DTQTLDVLp-PQVLRLRKVQHLRRCIWTSL-NKAD--DVI-CLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAG 373
WP_011096030 292 LMNTAPTVnsYKIRRFTHITHVASFISGTF-KPNI--SPLrALSHIHPTGAIAGEPRERALEIIKEIEPFDRELYGGAIG 368
WP_002530655 249 FCDTVHVPdcPGCVYNDASTYLVTDVTGIH-SPDQg-SCLaLVQALCPPAFVTGLPPHCALSVLAEIEHVDRGRVSGPTG 326
WP_010079983 276 VVDLADDDpvPTVLTLPNVHHLATSVRGRLrDGRG--TVLdVVAALHPTAAVGGTPTPDAVRVIAEVEPVDRGRYAGPVG 353
YP_003155795 296 VAEELEVSpePFVLRLPGLEHLASDVSARLr-EGT--TSLdVASRLHPSAAVSGTPREDADEIIADLEPHDRGGYASPVG 372
WP_015071312 276 FCSAVRHSpyPGLVWAAEDRLLATDVTGAV-LPDT--RSLaVVGALHPAPFVSGLPPWKAADTLAEVEEVDRGRITGPLG 352
WP_065248683 300 LGVSLPPSegPFVLHLPGIEHLATDIRGVA-PDGL--GILeIAGALHPSAAVSGTPRTAANEVIAQLERVDRAGYASPVG 376
WP_069599704 316 VADDVSVDerPHLLPLANVIHSASDASAHL-PEDSclNALdIAAAVHPTAAVGGYPQASAVAHVDELEPLDRGRYSGPVG 394
WP_084637251 312 YVTHMDAHiePFVLELPNVWHLASDVTAKL-PSKDapNALdLAEILHPTAAVCGTPTVAAASAILELEGMDRGRYAGPVG 390
WP_114593465 226 LCDDLEVDadPWLLRLDNLQHLATRLTGTL-REPT--HVLeLVGALHPTAAVGGTPREVAVPLIGSLEGMDRARYAGPVG 302
2EUA_A       374 YLSLQ-QSEFCVSLRSAKI-SG---N-VVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLL-QME 431
WP_011096030 369 WIGQDsSCEFTLPIRCAQL-NR---G-HIKAFAGCGIVKSSIPQKELEESTLKFKTIIDAI-S-- 425
WP_002530655 327 WVDSLgNGQWVTDCRGGQI-DAtdpS-LVHIFSGHPVGHDDDADVLSAEAEHRIDVLRDLFlT-- 387
WP_010079983 354 WLDQDgDGEIALALRCGQQ-VP---G-GVRLQAGGGMVPGAVPEEEVTEIRAKFLPMRRAL-GVA 412
YP_003155795 373 WMDGSgDGQWAIALRMAHVvDE---R-TVVLQAGGGLVAASDPVSEHAEALAKCRPMLRAL-RGE 432
WP_015071312 353 WVDRDgDGEWVTDWRGAQI-DGtdpN-LAHVFTGQAVSRDDDITALSEELEAKVRATLAVV-Gl- 413
WP_065248683 377 WIGADgNGELAIALRMAHV-HG---T-TLTVQAGGGLVRDSDPLTEHAEALAKTRPIVRAL-ASL 435
WP_069599704 395 WMDDRgNGQFGIALRCGQL-EDr--N-RIRLFAGAGIMPDSDPLAEVAETEAKFAPMRRAL-GLE 454
WP_084637251 391 WIDSHgNGEFGIALRGGIV-ES---AhRIRLFAGCGVVAASDPASELAESWAKMRPMQQAL-Nl- 449
WP_114593465 303 VVRGNgDGTFGIALRCAQL-TA---R-RARLFAGCGIVAGSLPEAELEETRLKLNTMQQAL-GAR 361
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