Conserved Protein Domain Family
ORF_2_N

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pfam18492: ORF_2_N 
Open reading frame 2 N-terminal domain
This is the N-terminal domain found in ORF 2 (open reading frame 2), a protein encoded just downstream of asp (A. sobria serine protease). The ORF 2 N-terminal domain is essential for proper ASP folding. This domain is intrinsically disordered but forms some degree of secondary structure upon binding ASP.
Statistics
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PSSM-Id: 408285
Aligned: 10 rows
Threshold Bit Score: 106.728
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_034835204   44 VTQNVVKL-NNRNFVVNAPAVRAAsfasATAAAPAKPSVTKGM-TLTSSLTGQPVKVTGRFTVLLDKGVDASEFATRHGL 121 Endozoicomonas...
jgi:Sama_2216  31 SDQYQQNA-TRADFLGLNDNFYVK----TDKGVQKAKRLIQGE-QLVTEEGEPFATLTGKFVVKVKPGVIPATFAADAGL 104
EKE87011       36 VVAEAKKLpQGVAKQRVYKNYR------LANGVAKNDALTSGA-RVFNEVTRELGTVSGNVTVLTNDGVNVGKIAQQFGL 108
EGM79199       67 ADTSNGTL-SGRAL--------------VKQTVVNTEGTVKTDaVVRNLLTGELGVVTGRLSILASDTAALQSLQQDFGL 131
KKA44339       17 VSAGTVQL-NGKDYVVVETDSN------ARNMSGEQMGVMVGD-KVAVSAQSTPLTVTGSILVKVSE-ASASQLAQKYGL 87 
tigr:AHA_2688  31 KQYRTIEV-NGQTYLTPDNGSKQRva-rSADGKAPRQTLRSGD-VLLQGVASPQLTASGTLLVEADDN-QASALASRHGL 106
WP_047872581   55 VPAGDVQI-AGEQFTKLAPAAQTRaa-rTFSVPGAPLTVQAGDrLLQAGSHQGPVEVSGGILVRLSPGVSAQQLAQDSQL 132 Photobacterium...
WP_047887526   38 HAAGEVEM-NGKRYTKLAPTAAAPg--mLRAAPTVSEGLFVGDrLLADGSTLGPVEVSGGIFVRLAPGVSAQQFAADNQL 114 Photobacterium...
WP_022551956   32 APGEKVLI-NGQTFFKEKEESFSLl---RFLGFDNPVEVYAGD-ALTDETGIETHKASGVILVRASQD-QAKALAKEYGL 105 Vibrio nigripu...
jgi:Swoo_4487  34 EASESVVV-NGQTFNKVIEPS-------ATADFADTVKLFAGD-LVTKGSFNLTSKATGLVFVTLIEGQDAKAVATDLDL 104
WP_034835204  122 SLYKQMGSSrlA-IFEAAESVDLLALDAQLREASELSSVKIELLENLNQP 170 Endozoicomonas numazuensis
jgi:Sama_2216 105 RLDWQNDTQ--LlILAASEGSDLLALLDKLKQNSQVERVKLDRAVLKQQP 152
EKE87011      109 SVVNQESRVglA-VLSAPANTDLTALVEQLKSSDLVKSARIEIVEALNQP 157
EGM79199      132 KLVKAVGDK--IaIMQAPAGANLTELVDSIRKSGLVKEARLDVVEKLNKP 179
KKA44339       88 DFVSYLDGV--A-LLEATPGTNVAELEKALNQELE-TPVNLELNPQNQRP 133
tigr:AHA_2688 107 RFKQSSGGI--A-LLEAKPGTDLNAVATALKQEG--VKVQIELAGALKQP 151
WP_047872581  133 TLVFSTPEI--A-VLKAPAGHNLLPVVADLDSDRRVEHVSLDLVSGANLP 179 Photobacterium aphoticum
WP_047887526  115 DVVFTGTDI--V-LFKAAAGGDLLPLLAELERDPRVSQAKLELVGQRNRP 161 Photobacterium ganghwense
WP_022551956  106 EVVSQAGSI--S-LLKASTSTELLNLASQLEAKG--VTLQVELVNSAEQP 150 Vibrio nigripulchritudo
jgi:Swoo_4487 105 KLVFANGNS--A-VYKAAENVDLLNLNDELFNDSRIKAVKIELANNKYNP 151
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