Conserved Protein Domain Family
DUF4670

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pfam15709: DUF4670 
Domain of unknown function (DUF4670)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Statistics
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PSSM-Id: 464815
Aligned: 7 rows
Threshold Bit Score: 404.719
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ELK04846      397 NETSPLTQRPEKQGAQQSLEAAAQKTGEPQSCINKEL-ICSNRKEFYTRKLHIDMMPFLKESGNELDYH-EPGG-PLGEN 473 
XP_023366151  618 HETSRLTQTTEKQGAQQSLEAAAQKTGEPQSCINKKL-ICSNGKEFYPRKLHIDMTPFLKDSEDALDYHeEPEE-SPRES 695 
XP_014343564  308 KHRKPYTGNHEESESEKDYENSTE-TGEYYNRTKKGLgSVARRRKMGAGQHHEHLSGFAED--EILSSGeEAGQdPLFQQ 384 
EHB15491      463 asERPL------PGSLQPLETAAQKTGEPQSCINKEL-MCSNRNEFSTSKLHIDMTPFLKESGEELDSQeEPEE-TSGEN 534 
A7YY35        585 NETSPLTQKPENQGAQQSLEAAAQKTGEPQSCINKGL-ICSNRKEFYTRKLHLDMTPFLKASREEMDDHeEGGE--LREN 661  cattle
XP_008257204  621 FETSPLTQTTEEQGAQQSLEAAAQKTGEPQSCTNKGP-ICSNRKEFSTRMLHIDMTPFLK-GGDALDSSeEPGG-PLGGA 697  rabbit
XP_017829133  600 YETSPLTQTTEKQGAQQSLEAAAQKTGEPQSCINKGL-ICSNRKEFYTRKLHIDMTPFLKESREALDYQeEAGR-SLRET 677  white-tufted-...
ELK04846      474 HRD-TQDQEPRSVTLGPLSATPADHIRTPEADAVGKV-GKDYNVHHLHRGLPGCEPESPERLSPIDTSLLPKEREGKTEP 551 
XP_023366151  696 HQD-SQDPEPRSVSISTLSAPLAEHIQTPEADTVQNG-GENYDAHHLHREIPGHGPESPQKLGAVDTSVFPREREGKAEP 773 
XP_014343564  385 YSDsSLKRRMRQRSPSVLGPAAGSHSRQGLRGVTESGnNEEVDENYENGSGPRRRRRRRRKFTASWKDEL-LANYARNEP 463 
EHB15491      535 DEDsSQDPEPRSVILKPLSAPLGKHIQILEADTVKNMdGDD-RAHGFHTVLPGPASESPENLGVVDVSSLPRAKKEKTES 613 
A7YY35        662 HPD-AQDPVRRNMTLDPLCASLAKHMQTPEADTVQKA-SKDYNVHHRHRGLSGHGPDSPEGLDPIDTSFLPRGKEGKTEP 739  cattle
XP_008257204  698 DQD-GQ--EPGMATLVPLSTSLPECIQTPEADSVKETdGEH---SAPPRGLPRHRPDSPESPAAVATSL----------P 761  rabbit
XP_017829133  678 HHD-DQDPEPRSMTLDSLSASQTEHIQTPDADTVQNV-GRDYDVHHLHRGLLRHRPESPERLSAVYTSLLPREREGKAEP 755  white-tufted-...
ELK04846      552 RLFNQQTPVSISHe---------------------EMELIDKVKRKKKTKTDKS--------KMPE--------GEREGK 594 
XP_023366151  774 SPFGQQTSGSISH----------------------ERELNNKAKGRKRTKTDKI--------KAPK--------REQEGR 815 
XP_014343564  464 --LTEEEEESLSNels----------------kqaENLSAESVSRGKGRKKNSTkertsgsvKTTK--------DSERDK 517 
EHB15491      614 RLLNQHAPASIHP----------------------ERELIDKTKRKKKTKIDKT--------TTPT--------RQREGR 655 
A7YY35        740 RLFNQKTSNNISN----------------------EMELIEKAKSRKRAKTDKS--------KAPK--------REKEGK 781  cattle
XP_008257204  762 GWFSQRPPASLGHvnentdelhlkslpgthrghqeEEESIDKANRRKGTKTDKT--------KGTKtdktkapgREREGK 833  rabbit
XP_017829133  756 RLFSQET-ASISH----------------------ERDLIDKAKRKKKPKTDKT--------KALK--------REREGK 796  white-tufted-...
ELK04846      595 AHVEAKAAVGKARELKAKKKSElipkgKKTGAKRKKTQKERNLEI-AAE--LDGPDVINSKETEDTSDRGFFPLGSVAED 671 
XP_023366151  816 VFREAEAAVGKSKDSNTKQKLG-----KKTGAKRKRTQKARNLAIgGAE--LSGPDVINSKETEDASDRGLFPSDSVVED 888 
XP_014343564  518 RHGRAEFVVGKPREKRDDEK-----------PKKKRLQQASGAAVeGGEevLSGEEEVWSSGDEGRFEVGAMSNRS---- 582 
EHB15491      656 VPGEAETAGGKSKDSKAEKKSEpipkrRDPRSKRKRTQKEVNVEM-AAG--LSGPDITSSKETEGASTGGSLPEHPSAED 732 
A7YY35        782 LHEEAEAAVGKSKESKAEKKSQliskgKKTGAKGKRTRKEGNLET-AAE--LSGPDGINSKETKDRSGGGFFRSGSGVED 858  cattle
XP_008257204  834 VLGAAEAAGGKSRHSKPERKAEliskaKRPVVKRNRPRKGRNREL--AE--LTGPDV-HSTRTEDASARGCFSADS-VEG 907  rabbit
XP_017829133  797 IYREAEAAVGKSKDSXAKNNLE-----KKSGAQRKRTQKERNLEK-AAE--QTGPDVIHSEETEDTSNRGSFASDSFVED 868  white-tufted-...
ELK04846      672 PWLSPRYDAEESQVSIDGRSSP--TQIVPVTENMDSKEERSYEDPSK---------------------ALLAKREQe--- 725 
XP_023366151  889 PWLSPKYDAQDSQVVIDGKSSPsqTQTITVTGNTGSEEERSYDDPSK---------------------ALLFKREQ---- 943 
XP_014343564  583 ---ASPSQAEGRQFTAKERSNSrlSVVFVVT-------PVSEELPKS---------------------TLIENLSKngql 631 
EHB15491      733 PWPPAMYNAQDIHLSIDARSSP--IQTTVVTGSIEAEEERCRAAPSQ---------------------ALLTQREQe--- 786 
A7YY35        859 PWVSSKVEAPESQVSIDGRSSP--TQTAAVPGNMEPEEDRSHEDPSK---------------------AFLVKREQe--- 912  cattle
XP_008257204  908 PWLSHKDEFPETQVSIDSRLSP--TQAVTAAGDLEPEEEESQEDPSK---------------------GLIPNREQe--- 961  rabbit
XP_017829133  869 PWLSPKYDAQETQVSLDGRSSP--SQIATVTGNMESKEERSCEDPSKvksdvlsltegvlsslgtsaeALLTKREQe--- 943  white-tufted-...
ELK04846      726 -NASRDRLRAERAEMRRLEVERKRREQEEQRRL-WQEQLERAEKMKEELELEQRSRAEEIRLRKQRREDERQRQEEEERK 803 
XP_023366151  944 -KDSRDRLRAERAKMRQLEVERKRKEHEEQRRL-KQEQLERAKKMEEELELEQQRRTEENRLRKQRLEEEQQQQEEEERK 1021
XP_014343564  632 tKSARQVVREEQAKQRRMEVERKRQEREEQKRQeQQEKQEREDQMRKELEREQRKIFEAIRLRKQQQEDERLRQEEEEAN 711 
EHB15491      787 -KEARDRLRAQRAEMRLLEVERKRREQEEQRRL-QQEQQERAKKMREELELEQQRRSEEIRLRKQRLEEEREQQEESERK 864 
A7YY35        913 -KASRDRLRAERAEMRRLEVERKRREQEEQRRL-QQEQLERAERMKEELELEQQRRVEEIRLRKQRLEEERQWQEEEERR 990  cattle
XP_008257204  962 -QASRDRLRAQRAEKRLLEVERKRREQAEQRRR-QQEELETAEQMKAELELEQQRRKEEMRLRKQRLEEEEQRRAEEERK 1039 rabbit
XP_017829133  944 -KASQDRLRTERAEMRRLEVERKRREQEEQRQL-QQEQLERAKKMEEELEQEQQRRAEEIRLRKQRLQEEQQRQEEEERK 1021 white-tufted-...
ELK04846      804 QWLQLQAAQERARQQQEEFRRKLQEIQRKKQQEEAERAEAEKQRQKELEIQLAEEHKRLMEMAEEERLEYKRQKQEAEEK 883 
XP_023366151 1022 QRLQRQAAQEKARWQQEAFRRKLQELQRKKQQEEAKKAEAEKERQKELEMQLAEEQKRLMEMAEEERLEYQRQKQKAEEK 1101
XP_014343564  712 RARQEQMERERAHRQQQEYHRKLLQLQQQRQQEELQRAAENERRRKEEEERLAEECKLLAGMSEEERVEYLRKKQEEEER 791 
EHB15491      865 QHLQWQAAQERARQQQEELRRTLQERQRKKQQEEAEKAEAEKQRQKELEMQLAEEHKRLMEMAEEERLEYQRQKQEAEKK 944 
A7YY35        991 QWLQLQMAQERARQQQEEFRRKCQELQRKKQQEEAERAEAEKQRLKELEMQLAEEQKHLMEMAEEERLEYQRRKQEAEEK 1070 cattle
XP_008257204 1040 QRLLMQAAQQRARLQQEEFRKKLRELQRKQQQEAAERAEAEKQRQKELEMQLAAEQKRLMEMAEEERLEYLRQKQEAAAK 1119 rabbit
XP_017829133 1022 QQLRLKAAQERARQQQEEFRRKLQELQREKQQKEAERAEAEKQRQKELEMQLAEEQKRLMEMAEEERLEYQQQKQEAEEK 1101 white-tufted-...
ELK04846      884 ARLEAEERRQKEEeAARLALEEAMKQTQELARQ 916 
XP_023366151 1102 AQLEAEERRLKEE-AIRVAQEEAMKQAQEQARQ 1133
XP_014343564  792 RRQEMEERRRRAEeQAKLVFANIKWQAELSARE 824 
EHB15491      945 ALLEAEERRQKEEaTAKLALEEAMKQAQEQASE 977 
A7YY35       1071 TRWEAEDRRQKEKeAARLAQEEAMKQAQDQARQ 1103 cattle
XP_008257204 1120 AQWEAEERRQQEEeAARLALEEATQLAQEQARQ 1152 rabbit
XP_017829133 1102 AQLEAKERRQKEEeAARLALEEATKQAQEKARq 1134 white-tufted-ear marmoset
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