Conserved Protein Domain Family
DUF4693

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pfam15764: DUF4693 
Domain of unknown function (DUF4693)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 238 and 436 amino acids in length.
Statistics
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PSSM-Id: 464854
Aligned: 13 rows
Threshold Bit Score: 334.861
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGW09751     152 PSRSAdPECRRRSRGDRTQERTEAQV-TGSG----------PGLRGQQM----------------AP---GAVPPSTELF 201
XP_001163226 148 PAKGH-PERRLLSVGDRTRVGMGART-PRPG----------AGLRDQQM----------------AP---SAAPQAPEAF 196
XP_023413274 115 PARSL-PEHRLLSTRERTSLGRGARA-TRPS----------LG--DQQV----------------TP---SVTPLVPEAF 161
Q3ZBU3       146 PAKDL-PGHRLLLVGDGAHMGQGAGA-NKPE----------AGLRDQQI----------------VP---QAASQVPEAF 194 cattle
ELK10770     139 HAKGL-PDRRLLAVGDHSCLGRGAQA-AKTG----------PGPREQQT----------------FP---SVAPQAPEAF 187
XP_003478535 151 PTKGH-AEHRLPLVRNRSHVGLGAQA-TRLE----------LN-HGKKM----------------TL---SPAHHTAETF 198
Q6GQV0       150 PPKDY-PEHRLRSKGDKTHVRTQDQT-TGYG----------PDLRDQQM----------------TP---SSAHHTTELF 198 house mouse
ELW67827     365 PAKVC-PEHKLLSAGKRTHAGIGAQA---PG----------PGLRNQQV----------------AS---SAAAQVPETF 411
XP_031451047 282 PA------------GEGSSV--CGQQqLSDGrkrccdalglPGGAEEHThrgaeehthrgaeehtAG---AGS-ASPRAA 343 Ring-necked phe...
XP_013032230 250 RD-SS-GERNLVAAGRQLIDAGKKSC-GSRG----------ESGRKENP----------------TAegiSGGSTSPQTV 300 Anser cygnoides...
XP_023620256 140 PAKGL-PKPRLLSAADQTCTGRGPLA-AKPG----------PDLRNPQI----------------AP---SAAPQAPKAF 188 little brown bat
XP_020942422 147 PAKNL-PEHRLLSVADATCKRRGAQA-VKPE----------PGLRDQQM----------------VP---SAAAQAPEAF 195 pig
XP_002926585 147 PARGL-PECRLPSVGDHTAMGRGSRA-TKPG----------PGLRDQQI----------------PP---SAAPQAPEAF 195 giant panda
EGW09751     202 TLKEKGTLLQLPVAFRKAASQNSR-------LWAQ-----LSSIQASDSTDv-TRAAKTEFLHKLQMAS--GSSSHRPSA 266
XP_001163226 197 TLKEKGHLLRLPAAFRKAASQNSS-------LWAQ-----LSSTQTSDSTD--AAAAKTQFLQNMQTAS--GGPQPRLSA 260
XP_023413274 162 TLKEKGTLLRLPMAFWKAASQNAH-------LWAQ-----IDSTQASDSAN---ATARTRFLLKMQAAS--GWPGVGLSA 224
Q3ZBU3       195 TLKDKGALLRLPEAFRKAASRNARlpmcassLWAQ-----LSSMQTRDSVDaaAATAKTQFLQKMQTAA--GLPSSMLSA 267 cattle
ELK10770     188 TLREKGTLLRLPMAFRKAASQNSR-------LWAQ-----LSTAQTSDSMDa-AMTSKTQFLQKMQTRS--GWPCSGLSA 252
XP_003478535 199 TLKEKGTLLKLPLAFRKAASRNSC-------LWTQ-----LNSTQTNDSTDa-TSAAKTQFLQKMQISS--STSSSKFSA 263
Q6GQV0       199 ALKEKGTLLQLPEDFRKAVSRNSC-------LWAQ-----LNSARTNDSTDa-TRAAKTQFLHKLQMAS--GCSSHRPSA 263 house mouse
ELW67827     412 TLQEKGSMLQLPVAFSKAASRNSRg------AWSRsleisLTCVQ-----------------------P--GQPSAGLSA 460
XP_031451047 344 VLQEQGCQLELPLPYRKAHTRNSR-------AWEK-------CRLCHTSAD--AAAARMHFTERTQSTF--RSPTPALSP 405 Ring-necked phe...
XP_013032230 301 TVQQQGCQLKLPHPYRKAYSRNCR-------AWEK-------SRLCQTSAD--AAAARKRFTERIQTTFefCSPTPALSP 364 Anser cygnoides...
XP_023620256 189 TLKEKGTLLQLPMAFRKAASQNSC-------LWAQ-----LSSTQTSDSTDa-TTSSKTQFLQKMQvtS--GWPSSGLSA 253 little brown bat
XP_020942422 196 MLKDKG-------------------------LWAQ-----LSSAQTSDSADa-AATAKAQFLQKMQTAS--GWP----SA 238 pig
XP_002926585 196 TLKEKGTLLKLPMAYRKAASQNSR-------LWAQ-----LSSTRTSDCGDa-ATTAKTQFLQKMKMTS--GSPGSGLSA 260 giant panda
EGW09751     267 AEVEAHVQSLRKARTLLRLHMQKELST-----------------------------APTDWMQEYRGLLILEGLQTIVGQ 317
XP_001163226 261 VEVEAEAGRLRKACSLLRLRMREELSA-----------------------------APMDWMQEYRCLLTLEGLQAMVGQ 311
XP_023413274 225 AVVEAEVGRLRKACLRLRLRMGTELAA-----------------------------APTDCVQEYRCLLLLEGLQATVGQ 275
Q3ZBU3       268 ----AEVGRLQKACSMLRLRMREELTA-----------------------------DPKDWTQEYRSLLTLEGLQALAGQ 314 cattle
ELK10770     253 PEMEAEVGSLWKACSLLRLRMGQELAA-----------------------------DFTDWMQEYRCLLTLEGLQAIVGQ 303
XP_003478535 264 VEIEMETQRLQKACALLRRRMQEELSA-----------------------------APVDWMQEYQCLLILEGLQTMAQQ 314
Q6GQV0       264 TEVEAHARILRKACMLLRLRMQKELAI-----------------------------APTDWMQEYRCLLTLEGLQTVVGQ 314 house mouse
ELW67827     461 TEVQEETQRLRRACSRLRLHMLEELSA-----------------------------APADWMQEYRCLLTLEGLQALAGR 511
XP_031451047 406 AEIEEELKALQDVPSRLSLYVEAESAD-----------------------------HPT-LQREYESLLTLEGLQSTVSQ 455 Ring-necked phe...
XP_013032230 365 AEIEEELKVLQDVPSLLSRYVEAEPAD-----------------------------HPT-LQREYESLVTLEGLQTTVSQ 414 Anser cygnoides...
XP_023620256 254 AEVEAEVGRLQKACLLLRLRMEEELTR-----------------------------DPTDWMQEYRGLLTLEGLQAIVGQ 304 little brown bat
XP_020942422 239 TEVEAEVGRLQKACSLLRLRMEEELMA-----------------------------DPEDWAQEHRCLLTLQGLQDMVGQ 289 pig
XP_002926585 261 AQVEAEVGLLRKACSLLRQRMEEELSAepadwmqeyhclltleglqxlhrmqelraAVA--------------------- 319 giant panda
EGW09751     318 CLHR---VQVLQA----------A---------------------VTEQL---------PGLHLVEKPTQASSLGGGEMD 354
XP_001163226 312 CLHR---LQELRA----------A---------------------VAEQP---------PRPCPVGRPPGASPSCGGRAE 348
XP_023413274 276 CLHW---LQELRK----------V---------------------VAKHH---------LELCPSGMPARASCLCEGGAD 312
Q3ZBU3       315 CLHRlqeLQELRS----------A---------------------VVEQP---------QGPWPEG-PPRAALPCGGGAD 353 cattle
ELK10770     304 CLHR---LQELQT----------V---------------------VVEQQ---------QGLWPEERLPRTSLPCGGGTV 340
XP_003478535 315 YLHK---VQELCT----------A---------------------LTEQL---------PGSNLMGRPLQASLPSGGHVC 351
Q6GQV0       315 CLHR---IQVLQA----------A---------------------VTEQL---------PGECLAETRTQASSVCGGEVD 351 house mouse
ELW67827     512 CLHQ---LQELRA----------A---------------------TEGQ------------PCPVERPPRAPLPCEGRVD 545
XP_031451047 456 CLHK---LQLLRAavesqrrlhpD---------------------CTGD----------QGDCCAAH-AAGGRVCGSAGT 500 Ring-necked phe...
XP_013032230 415 CLHK---LQLLQA----------A---------------------VESQMrlhpdcagdVGNCCPSCVPARGRACGSAGT 460 Anser cygnoides...
XP_023620256 305 CLHR---LRELQA----------EesgkevpgchprrphspvlteVVEPQ---------LGPWPEERLPMASLPCGGGAD 362 little brown bat
XP_020942422 290 CLHR---LRELHPa-------------------------------VGEQL---------LRPWPEGRLPRASSPCGGGAD 326 pig
XP_002926585 320 -----------------------------------------------GQQ---------LGPWPEGRCPSASMPHGGSTD 343 giant panda
EGW09751     355 TSWSPELLLYSSTEELQTLATLKLRVAMLDQQIHLEKVLMAELFPLINTQEAGGSPQLALCRAAYSLLCEGGEQFLTVLR 434
XP_001163226 349 PAWSPQLLVYSSTQELQTLAALKLRVAVLDQQIHLEKVLMAELLPLVSAAQPQGPPWLALCRAVHSLLCEGGARVLTILR 428
XP_023413274 313 AAWSPQPLLYSSTQELQTLAALRLRVAMLDQQLHLEKVLMDELLPLVRTQRPC---CVAVCRAVHSLLCNGGQHFPTVLQ 389
Q3ZBU3       354 PVWSPQLLLYSSTQELQTLAALRLRVAMLDQQVHLEKVLMAELLPLLSEQEPLGRPWLALCRAAHCLLCEGGQRFLTVLQ 433 cattle
ELK10770     341 PTRNPQLLLYSSTHELQTLAALKLRVAMLDQQIHLEKVLMTELLPLVTTQEQLGLPQLALCRAVHSLLCEGGERFLTVLR 420
XP_003478535 352 TSWGPQLLLYSSTQQLKTLGTLRLRVAMLEQQIHLEKVLMAELLPIVSTQEPQGQPWLALCRAAHSLLCEGGERFLTVLR 431
Q6GQV0       352 SACSPELLLYASTEELQTLATLKLQVALLHQQIHLEKVLMAELLPLINTQDPGGPPWLALCRAAYSLLCEGGERFLTVLR 431 house mouse
ELW67827     546 PSWRPWLLLYSSTQELQTLAALRLRVAMLGQQLHLEKVLMAELLPLVCTLEPRGPPWLALCRAVHSLLCEGGERFLTILR 625
XP_031451047 501 LAVP--LLCYSRLQELRDLFALKLQVSMLHQEIALQKLTMTELLPVLDSRPFSGPSAAQLYRAMYTQLCEGGGRFPVLVR 578 Ring-necked phe...
XP_013032230 461 LAVP--LLWYSSFQELRDLFALKLQVSVLHQEIALQKLTMTELLPVLESKAYPEASAAQLYRAIYTQLCEGGERFPVLVR 538 Anser cygnoides...
XP_023620256 363 PTWSPQLLLYSSTQELQTLAALRLRVDMLDQQIHLEKVLMAELLPLVSMQEPLGPPQLALCRAVHSLLCEGGQRFLTILR 442 little brown bat
XP_020942422 327 PVWSPQLLLYSSPQELQTLAALRLRVAMLDQQIHLEKVLLAELLPAVSKPEALGPRWPALCRAVHSLLCEGGKHFLTVLR 406 pig
XP_002926585 344 PAWSPQLLLYSSTKELQTLAALRLRVAMLDQQIHLEKVLMAELLPLVSKQDPQGPPWLALCRAVHSLLCEGGERFLTILR 423 giant panda
EGW09751     435 DDP 437
XP_001163226 429 DEP 431
XP_023413274 390 DEP 392
Q3ZBU3       434 DEP 436 cattle
ELK10770     421 DEP 423
XP_003478535 432 EDP 434
Q6GQV0       432 DDP 434 house mouse
ELW67827     626 EDP 628
XP_031451047 579 DEL 581 Ring-necked pheasant
XP_013032230 539 DEL 541 Anser cygnoides domesticus
XP_023620256 443 DEP 445 little brown bat
XP_020942422 407 EDA 409 pig
XP_002926585 424 DEP 426 giant panda
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