Conserved Protein Domain Family
CE4_DAC_u4_5s

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cd10973: CE4_DAC_u4_5s 
Putative catalytic NodB homology domain of uncharacterized bacterial polysaccharide deacetylases which consist of a 5-stranded beta/alpha barrel
This family contains many uncharacterized bacterial polysaccharide deacetylases. Although their biological functions remain unknown, all members of the family are predicted to contain a conserved domain with a 5-stranded beta/alpha barrel, which is similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, belonging to the larger carbohydrate esterase 4 (CE4) superfamily.
Statistics
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PSSM-Id: 213028
Aligned: 26 rows
Threshold Bit Score: 140.485
Created: 14-Jul-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative activeputative metal
Feature 1:putative active site [active site]
Evidence:
  • Comment:based on similarity to other CE4 superfamily members

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1               ##                                                       #   #           
NP_720132     76 KTVAITFDDGYrSIATTAHPILKEFGFPYTLFVAIEPIkqkfteMMTWEELIQLSKe-GADIANHSWAHEHLirrldne- 153 Shewanella onei...
ABK83373      61 NWLVLTIDDGYkSFYKNGFPIFKEFGYPFTLFVYVEASqkkygdYMSFDDIKDVQNw-GAEIGYHSYSHKYMtyl----- 134 Campylobacter f...
ADU96695      68 KTVVITIDDGY-RTTYKAFKLLKKYRIPATVFLYMEAVgry-pdFLTEKQIEEMKRsgLIEFENHLYSHPNLgllrlkl- 144 Thermovibrio am...
YP_001470535  74 DAVVFTVDDGYrSVYDYAYKIFKKHEVPFTVFIQVGAIgy--pdYLTWEMIKEMLKd-GVEFANHSYTHTDFpalltkm- 149 Thermotoga lett...
YP_001357303  80 NWVILTIDDGF-KSFLNALPLFLKFHYPFTLFLATKPIenrypdYLSWKDLKKIAQ--YGEIAFHSHTHPHLvdl----- 151 Nitratiruptor s...
ZP_01871873   72 KIVVFTIDDNYkSFYKNGLPLFKKYNFPFTLFVYTKATtqkwgdFMRWNEVKECAK--YGELGVHSYAHPHLakl----- 144 Caminibacter me...
ZP_03129751  152 KSCIVTIDDGWvSAYNNAWPILKEFKYPFTLFIYINYVgtg-gkSMSWDQLAEMRDa-GVDIESHTYSHSDLkkpgnlvd 229 Chthoniobacter ...
YP_001878217 187 KCVMITIDDGWkSVYTDAYPILKETGFPFTIFPYTKFItgr-gsAMSPAQIQEMLNn-GATLGSHSVSHLYPrswraaqr 264 Akkermansia muc...
ZP_02927960  156 ESVVITMDDGWlGVHEYCFPILKEFNYPFTVYLYKNYVnrg-grSLTLDQIREMMKy-GAELGSHSVSHQALtarhgkt- 232 Verrucomicrobiu...
XP_002538490  66 HAVIITIDDGW-KSALTAKSKLNAYGYPYTLALYTQMQdigsalYLSKADIKEFAQdpSCTIANHSYSHSAPvmrg---- 140 castor bean
Feature 1                                                     ###                                
NP_720132    154 -----------sqiqwlpRIKANILATENAIREATGq-nFNMLAYPYGEYnqAVQDMLTENGfVAFGQQSGAAgp----y 217 Shewanella onei...
ABK83373     135 ---------------nesEIKDDFEKGIQIFEHNLGy-kPQYFSYPYGEYnqTITNMAKEYGlEASFNQNSGAvsasssi 198 Campylobacter f...
ADU96695     145 -----------pkeeylrVLRREERLSRQRFKKLIGr-ePRFLAFPYGDYdrLSVEFFLEKGyKLLFTQDRGSy-----g 207 Thermovibrio am...
YP_001470535 150 -----------tlkemldYFKQDFEKAQQVFLNNTGk-eMRYYAYPYGYYipEMIDVLRNEGvKLAFSQNPGPyi---ss 214 Thermotoga lett...
YP_001357303 152 ---------------snqEIRNDTKKGLELFIKRLGy-iPKYYAYPYGEYneRVKRVIKSFGfTAICNQNTGAis---kk 212 Nitratiruptor s...
ZP_01871873  145 ---------------sneEIINDTKKAISEFKKHIGf-vPNIYSYPYGEYneRVKKIIKKFF-SYIANQNPGAid---lt 204 Caminibacter me...
ZP_03129751  230 kkaaegirkdvaalgldgWLRKEIIGSKQVLEKQLGi-kCNVFAYPFGRWtpKAVEIVKEAGyEAAFTVYGQQlh---ps 305 Chthoniobacter ...
YP_001878217 265 ----------kgtqavldLATAEIGNSRKILQEKFPgssVEAYCYPGGFIlpEMISKAEDAGfQAAFTVIPKKvt---kd 331 Akkermansia muc...
ZP_02927960  233 ------------deqyhkWLEVEIVESKKFLEETFGv-pCRTFAYPYGNKsdEIAQMCLDAGyEAAVTVNPQKtt---wd 296 Verrucomicrobiu...
XP_002538490 141 ---------------spqKARVDLERAQTDIENMTGr-rPELFVYPYGIVnrPLRGVVASLGfTGAFGIEPEKplg--pg 202 castor bean
Feature 1                       
NP_720132    218 SPLTALPRFPVAGQY 232 Shewanella oneidensis MR-1
ABK83373     199 GDLDRIPSMDGTNLK 213 Campylobacter fetus subsp. fetus 82-40
ADU96695     208 GRGKLVPRMAIVGSQ 222 Thermovibrio ammonificans HB-1
YP_001470535 215 YGAFEIPREPLLEDW 229 Thermotoga lettingae TMO
YP_001357303 213 SDIYDLDRIALVGKV 227 Nitratiruptor sp. SB155-2
ZP_01871873  205 TPLDDIDRIALTGKV 219 Caminibacter mediatlanticus TB-2
ZP_03129751  306 SQAELLGRYAVEQDK 320 Chthoniobacter flavus Ellin428
YP_001878217 332 TDRWRIHRYMVFGKD 346 Akkermansia muciniphila ATCC BAA-835
ZP_02927960  297 TPNGKLPRFVQIGDK 311 Verrucomicrobium spinosum DSM 4136
XP_002538490 203 TDPLNIPRYTVITMA 217 castor bean

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