Conserved Protein Domain Family
PD-C2-AF1

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pfam09310: PD-C2-AF1 
POU domain, class 2, associating factor 1
Members of this family are transcriptional coactivators that specifically associate with either OCT1 or OCT2, through recognition of their POU domains. They are essential for the response of B-cells to antigens and required for the formation of germinal centers.
Statistics
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PSSM-Id: 430516
Aligned: 4 rows
Threshold Bit Score: 368.124
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_008119288   7 SAPEPPPpqpSPRPYQGVRVKEPVKELLKRKRGSLqnANGATAAATTVFFPHQSLPSYSPAGQVCADSEFVASPL--VDD 84 
Q90ZH6         7 SASEQQP---QPRPYQGVRVKEPVKELLKRKRGNV--HNATAAAATTVVLPHQPLPSYSPMGQPCIDVDAAAPALpgAEE 81  chicken
XP_001381387  31 SAPEQTPv--PPRPYQGVRVKEPVKELLRRKRGLA--SSGLTVAATTVVLPHQPLATYATMGPSCLDMEVPTSTV--TEE 104
1_pfamImport   1 TAPEQAPa--PPRPYQGVRVKEPVKELLRRKRGHA--SSGAAVTPTAVVLPHQPLATYTTVGPSCLDMEVSASTV--TEE 74 
XP_008119288  85 GTLYSGWLAQPSPATLQPLTQWAAYPDYVPHEAVSCPYTGEMYVQPVCPSYTLVGTSSVLTYASQPLITNLAARStSAPA 164
Q90ZH6        82 GALCSSWLSQPSPSSLQPLTQWTTYPDYVSHEAASCPYTADMYIQPMCPSYTLVGPSSVLTYASQPLITNFTPRS-STPA 160 chicken
XP_001381387 105 GALCTGWLSQPAPATLQPLTPWTPYPEYMPHEGVSCPYSTDMYVQPVCPSYTVVGPSSVLTYASQPLITNFTTRN-ATPT 183
1_pfamImport  75 GALCAGWLSQPGPATLQPLAPWTPYTEYVSHEAVSCPYSADMYVQPMCPSYTVVGPSSVLTYASQPLITNVTTRSaAAPA 154
XP_008119288 165 VMPHLDMMEQQGPLSYFPWTQPISTLPAPSLQYQAASSALPAPQFLPLPVSVPETVSQDLEDTRKDLGGLSMEKLLLQEE 244
Q90ZH6       161 VVPQLEVTEQQPPLTYFPWAQPLSALPAPTLQYQPASSTLPTPQFVPLPISIPEPAPQELEDARRVIGTLPIEKLLLEDE 240 chicken
XP_001381387 184 SGPQLEGTEHQAPLTYFSWPQPISALPSSTLQYQSPAPSLPGPQFLPLPISIPEPVPQDLEDTRRAINTLPIEKLLLEEE 263
1_pfamImport 155 VGPQLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDMEDPRRAISSLTIDKLLLEEE 234
XP_008119288 245 NHGIFDLSNSLPVEG 259
Q90ZH6       241 DNDTYVLNHALSVEG 255 chicken
XP_001381387 264 ESDTYGMNHTLSVEG 278
1_pfamImport 235 DGDAYALNHTLSVEG 249
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