Conserved Protein Domain Family
Sororin

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pfam09666: Sororin 
Sororin protein
Sororin is an essential, cell cycle-dependent mediator of sister chromatid cohesion. The protein is nuclear in interphase cells, dispersed from the chromatin in mitosis, and interacts with the cohesin complex.
Statistics
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PSSM-Id: 401560
Aligned: 9 rows
Threshold Bit Score: 86.8749
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002001522 566 ENVP-----PSAAATETstgpQSLTTIEPVDNNENVTNLVQLPNPRRALKYRSPLKDINILDVVVLPSWKKNVQQKNn-- 638
XP_002058484 488 ENMP-----PPAAAVAQ----ATPIKPSEDQENENFENYVQLPNPRRTLQHRSPLKDINILEVVVLPSWKKNAQPDK--- 555
XP_001993831 331 ENVP-----PAKETIVel--pMTSMVPSEGQENENLENFVQLPNPRRTLQHRSPLKDINILEVVMLPSWKKNV-PDPk-- 400
XP_002070529 414 ENMP-----P----------------VATPAGNENMENLVHLPNPRRTLQNRMPLKDINILEVVHLPPWKKNPLGQAtpl 472
XP_002031849 309 ENRP-----PPTIS--------KSMSINDQESEENAENFVHLPNPRRTLQKRTPFKDINILEVVTLPSWKKNVTTNVsk- 374
Q9CPY3        88 ENNP-----PLKVP-TKedlfKTCSVPGTPSSTPVLYTQNVEPDSGEAELDS---RDLEMSQKVRRSYSRLQSL------ 152 house mouse
NP_001094417  74 ENVErisevSTKRSKVLtsspAISAEPKTSVLSPILPSSSPPPQPTESE------QDSVWSKKVRRSYSRLSMGDKSfe- 146
1_pfamImport   1 ENAI-----SEKSQMVPkeatSKPSAPEIDVLSPIPVNIQMSSNQDN--------RDIVMSQKVRRSYSRLEMSLNSssf 67 
XP_001965923 410 ENVP-----PPITNTS-----QVSSYQVNDTSAEDVENYVHLPNPRRTLQKRTPFKDINILDVVVLPSWKKNVQTTPsk- 478
XP_002001522 639 ---TPTKESLssnqqqefnsnipgqqtsknptkesqtryeqQELNSYSPEHQcard--------kqeQQRQGCDLFGFED 707
XP_002058484 556 ---TPTKVSTar---------------------------nqNNVTISSPRQQsg------------rAQQSSSNLFGFED 593
XP_001993831 401 ---TPTRESMvrnq-----------------------vhfeHSIENISPGNLssrp--------allQRQKNSNLFGFED 446
XP_002070529 473 kdeSALRDAI-------------------------------SPITQRSSSDH---------------SRRESRNLFGFEE 506
XP_002031849 375 -evTPTRVAP-------------------------------RPMATSSPAQ----------------RSQTRSNLFGFDD 406
Q9CPY3       153 -----------------------------------------GCASTSTP---------------------GRRSFFGFEG 170 house mouse
NP_001094417 147 ---------------------------------------spRPARSSSPN--------------------NRESLFGFER 167
1_pfamImport  68 -lySPTRKT--------------------------------DSSDTSTPNAV---------------PKSGRRSLFGFDK 99 
XP_001965923 479 -evTPSRQSQsta--------------------------ieRATVQASPSRTqtrvnlfgspnekspRQTEKRNLFGFEE 531
XP_002001522 708 FLSEEDEicvRepNQSVTKSCTDTTLHEKLQ--------RLKNLRP-------AQQELPQVSQAPMRH 760
XP_002058484 594 FLDEEDE---E--IANARAASQNVTLHEKLQ--------RLKDLRP-------ANEKLPQINREPLRH 641
XP_001993831 447 FLDDDDE---Q--PTSSHGQNQDVTLYEKLQ--------RLNRLRP-------ADKELPQVSKTPMHY 494
XP_002070529 507 FLDPNEH---SqhEVQATALSQDQTLNDKLQ--------RMKRLRP-------VDRDFPQVASTPLRY 556
XP_002031849 407 DLACEDI---L--TKSTTPSKGIAATSVSFN--------REVTPAL-------ANRSQMEVNTSECNE 454
Q9CPY3       171 ---PDD-------LPGVSPVVCSKLIETPKVpakdlvpaRTKDLVPdstkdlvPARTLPGISPPVVKE 228 house mouse
NP_001094417 168 LQTPEVM---KktEGSRSAPLGFMSLSLGSF--------NLSAADEsasnppeVDPNIPGV--CLGKK 222
1_pfamImport 100 LLNSEMP---EgeLRKSGSGTREKTANEKTLg-------TILPEEP--------DHNIPGV--VLAKQ 147
XP_001965923 532 FLNDSVA---A--TDRSPSRSQDVTLHDKLQ--------RLAELRP---------SNLPQVSSSPLRR 577
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